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Guangsheng Xu*, Huaixiao Luo, Zhanying Zhang, Liping Song and BingBing Yang
Department of Material Science and Engineering, China
*Corresponding author: Guangsheng Xu, Department of Material Science and Engineering, Xianyang, Shaanxi, China
Submission: January 31, 2018; Published: February 09, 2018
Study on Design, Fabrication and Properties
of Biomedical Porous Titanium
Mini Review
It has been shown that introducing porous structure in titanium
and its alloys implant material is an effective way to reduce the
“stress shielding” effect [1,2]. Interconnected pores in titanium and
its alloys not only can decrease Young’s modulus through tailoring
porosity but also can enhance bone ingrowth and improve fixation
[3,4]. Therefore, design, fabrication, mechanical behavior and
biocompatibility of porous titanium and its alloys have become a
research focus in this field. Development of fabrication methods,
together with studies of mechanical behavior and biocompatibility
is beneficial to improve the performance of porous titanium and its
alloys for implant applications.
First, effect of pore size, pore shape, pore topology and strut
material on mechanical properties of porous titanium and its
alloys has been studied by using computer simulation methods.
The results show that porosity increases as the pore size increases
from 200µm to 500µm, which also leads to the decrease in Young’s
modulus and yield strength of porous titanium. Porous titanium
with square pores has a low Young’s modulus and relatively high
yield strength compared with the circle and hexagonal pores.
Porous titanium has a good match of elastic modulus and high
yield strength when pore topology is changed from regular array
to staggered array. In addition, yield strength increases as the strut
material changed from CP-Ti to Ti-6Al-4V alloy. Therefore, Young’s
modulus and yield stress of porous titanium and its alloys can be
adjusted through designing pore size, pore shape, pore topological
arrangement and strut material.
Based on the results of the above simulation, porous titanium
is prepared by titanium mesh stacked-forced-sintering method
(TMSS) [5]. Structure and mechanical properties of the prepared
porous titanium are studied by tailoring pore structure parameters,
strut material and process parameters [6,7]. The results show that
porous titanium fabricated by TMSS has square pore structure.
There are no cracks and inclusions on the strut. Mechanical
behavior of porous titanium is anisotropic and sensitive to strain
rate. The flow curves are smooth, stable and no obvious serration
yield process. The strain for plastic platform region reaches up to
64%. It can obtain a fine match of low elastic modulus and high
yield strength by regulating the pore topology at the same porosity
[8]. Porous titanium prepared by Ti-6Al-4V alloys owns Young’s
modulus and tensile strength in the range of 9.5~12.2GPa and
360~505MPa, respectively. Fatigue fracture intensity level is about
40MPa at the testing condition of R =-1, f =10Hz and N=5*106. Heat
treatment has much more influence in the tensile stress but minor
influence in the Young’s modulus [9] (Figure 1).
Mini Review
263
Copyright © All rights are reserved by Guangsheng Xu.
Volume 3 - Issue - 3
Figure 1a: Schematic diagram of porous titanium.
1b: Microstructure model of porous titanium,
1c: Mechanical properties of porous titanium, bulk titanium and natural bone.
Research & Development in
Material Science
C CRIMSON PUBLISHERS
Wings to the Research
ISSN: 2576-8840
Res Dev Material Sci Copyright © Guangsheng Xu
264
How to cite this article: Guangsheng X, Huaixiao L, Zhanying Z, Liping S, Bing B Y. Study on Design, Fabrication and Properties of Biomedical Porous
Titanium. Res Dev Material Sci. 3(3). RDMS.000564.2018. DOI: 10.31031/RDMS.2018.03.000564
Volume 3 - Issue - 3
References
1.	 Long M, Rack HJ (1998) Titanium alloys in total joint replacement--a
materials science perspective. Biomaterials 19(18): 1621-1639.
2.	 St-Pierre JP, Gauthier M, Lefebvre LP, Tabrizian M (2005)Three-
dimensional growth of differentiating MC3T3-E1 pre-osteoblasts on
porous titanium scaffolds. Biomaterials 26(35): 7319-7328.
3.	 Takemoto M, Fujibayashi S, Neo M, Suzuki J, Kokubo T, et al. (2005)
Mechanical properties and osteoconductivity of porous bioactive
titanium. Biomaterials 26(30): 6014-6023.
4.	 Gepreel MA, Niinomi M (2013) Biocompatibility of Ti-alloys for long-
term implantation. Journal of the Mechanical Behavior of Biomedical
Materials 20: 407-415.
5.	 Xu GS (2013) The Chinese Journal of Nonferrous Metals 23(S1): 343.
6.	 Xu GS (2014) Rare Metal Materials and Engineering 43(11): 2778.
7.	 Li FP, Li J, Xu G, Liu G, Kou H, et al. Fabrication, pore structure and
compressive behavior of anisotropic porous titanium for human
trabecular bone implant applications. Journal of the Mechanical
Behavior of Biomedical Materials 46: 104-114.
8.	 Xu GS, Kou HC, Liu XH, Li F, Li J, et a l. (2017) Microstructure and
mechanical properties of porous titanium based on controlling young’s
modulus. Rare Metal Materials and Engineering 46(8): 2041-2048.
9.	 Xu GS (2017) Rare Metal Materials and Engineering 46(S1): 478.
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Study on Design, Fabrication and Properties of Biomedical Porous Titanium - Crimson Publishers

  • 1. Guangsheng Xu*, Huaixiao Luo, Zhanying Zhang, Liping Song and BingBing Yang Department of Material Science and Engineering, China *Corresponding author: Guangsheng Xu, Department of Material Science and Engineering, Xianyang, Shaanxi, China Submission: January 31, 2018; Published: February 09, 2018 Study on Design, Fabrication and Properties of Biomedical Porous Titanium Mini Review It has been shown that introducing porous structure in titanium and its alloys implant material is an effective way to reduce the “stress shielding” effect [1,2]. Interconnected pores in titanium and its alloys not only can decrease Young’s modulus through tailoring porosity but also can enhance bone ingrowth and improve fixation [3,4]. Therefore, design, fabrication, mechanical behavior and biocompatibility of porous titanium and its alloys have become a research focus in this field. Development of fabrication methods, together with studies of mechanical behavior and biocompatibility is beneficial to improve the performance of porous titanium and its alloys for implant applications. First, effect of pore size, pore shape, pore topology and strut material on mechanical properties of porous titanium and its alloys has been studied by using computer simulation methods. The results show that porosity increases as the pore size increases from 200µm to 500µm, which also leads to the decrease in Young’s modulus and yield strength of porous titanium. Porous titanium with square pores has a low Young’s modulus and relatively high yield strength compared with the circle and hexagonal pores. Porous titanium has a good match of elastic modulus and high yield strength when pore topology is changed from regular array to staggered array. In addition, yield strength increases as the strut material changed from CP-Ti to Ti-6Al-4V alloy. Therefore, Young’s modulus and yield stress of porous titanium and its alloys can be adjusted through designing pore size, pore shape, pore topological arrangement and strut material. Based on the results of the above simulation, porous titanium is prepared by titanium mesh stacked-forced-sintering method (TMSS) [5]. Structure and mechanical properties of the prepared porous titanium are studied by tailoring pore structure parameters, strut material and process parameters [6,7]. The results show that porous titanium fabricated by TMSS has square pore structure. There are no cracks and inclusions on the strut. Mechanical behavior of porous titanium is anisotropic and sensitive to strain rate. The flow curves are smooth, stable and no obvious serration yield process. The strain for plastic platform region reaches up to 64%. It can obtain a fine match of low elastic modulus and high yield strength by regulating the pore topology at the same porosity [8]. Porous titanium prepared by Ti-6Al-4V alloys owns Young’s modulus and tensile strength in the range of 9.5~12.2GPa and 360~505MPa, respectively. Fatigue fracture intensity level is about 40MPa at the testing condition of R =-1, f =10Hz and N=5*106. Heat treatment has much more influence in the tensile stress but minor influence in the Young’s modulus [9] (Figure 1). Mini Review 263 Copyright © All rights are reserved by Guangsheng Xu. Volume 3 - Issue - 3 Figure 1a: Schematic diagram of porous titanium. 1b: Microstructure model of porous titanium, 1c: Mechanical properties of porous titanium, bulk titanium and natural bone. Research & Development in Material Science C CRIMSON PUBLISHERS Wings to the Research ISSN: 2576-8840
  • 2. Res Dev Material Sci Copyright © Guangsheng Xu 264 How to cite this article: Guangsheng X, Huaixiao L, Zhanying Z, Liping S, Bing B Y. Study on Design, Fabrication and Properties of Biomedical Porous Titanium. Res Dev Material Sci. 3(3). RDMS.000564.2018. DOI: 10.31031/RDMS.2018.03.000564 Volume 3 - Issue - 3 References 1. Long M, Rack HJ (1998) Titanium alloys in total joint replacement--a materials science perspective. Biomaterials 19(18): 1621-1639. 2. St-Pierre JP, Gauthier M, Lefebvre LP, Tabrizian M (2005)Three- dimensional growth of differentiating MC3T3-E1 pre-osteoblasts on porous titanium scaffolds. Biomaterials 26(35): 7319-7328. 3. Takemoto M, Fujibayashi S, Neo M, Suzuki J, Kokubo T, et al. (2005) Mechanical properties and osteoconductivity of porous bioactive titanium. Biomaterials 26(30): 6014-6023. 4. Gepreel MA, Niinomi M (2013) Biocompatibility of Ti-alloys for long- term implantation. Journal of the Mechanical Behavior of Biomedical Materials 20: 407-415. 5. Xu GS (2013) The Chinese Journal of Nonferrous Metals 23(S1): 343. 6. Xu GS (2014) Rare Metal Materials and Engineering 43(11): 2778. 7. Li FP, Li J, Xu G, Liu G, Kou H, et al. Fabrication, pore structure and compressive behavior of anisotropic porous titanium for human trabecular bone implant applications. Journal of the Mechanical Behavior of Biomedical Materials 46: 104-114. 8. Xu GS, Kou HC, Liu XH, Li F, Li J, et a l. (2017) Microstructure and mechanical properties of porous titanium based on controlling young’s modulus. Rare Metal Materials and Engineering 46(8): 2041-2048. 9. Xu GS (2017) Rare Metal Materials and Engineering 46(S1): 478. Your subsequent submission with Crimson Publishers will attain the below benefits • High-level peer review and editorial services • Freely accessible online immediately upon publication • Authors retain the copyright to their work • Licensing it under a Creative Commons license • Visibility through different online platforms • Global attainment for your research • Article availability in different formats (Pdf, E-pub, Full Text) • Endless customer service • Reasonable Membership services • Reprints availability upon request • One step article tracking system For possible submission use the below is the URL Submit Article Creative Commons Attribution 4.0 International License