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Cardiopulmonary Bypass
Content Outline
• History
• Definition
• Cardiopulmonary Bypass goals
• Indications
• Cardiopulmonary Bypass Machine
• Oxygenator
• Cardioplegia Delivery
• Cardiopulmonary Bypass Circulation
• Cardiopulmonary Bypass Physiology
• Risk of Cardiopulmonary Bypass
• Organs affected by Cardiopulmonary Bypass
History
• With the advent of vascular techniques and refined tools, quite a few
advances had been made—repair of coarctation, the Blalock-Taussig
shunt for Tetralogy of Fallot, mitral valve fracture and many others.
• September of 1952, Lewis and his colleagues at the University of
Minnesota closed an atrial septal defect on a 5-year-old patient with
Hypothermia and inflow occlusion were the mainstay of operating inside
the heart for a few minutes
• May of 1953 when Dr. John Gibbon corrected an atrial septal defect in a
young woman at Jefferson Hospital in Philadelphia with the assistance of
a true heart-lung machine.
History
• In 1955, using some modifications, Dr. John Kirklin operated on a series
of 8 congenital cases with survival of 50%. at the Mayo Clinic.
• Dr. C. Walton Lillehei was developing the technique of "controlled cross-
circulation. This was a method by which a child was connected to his
parent as a "biologic heart machine." Over a 2-year period, Lillehei was
able to operate on 45 children, with 28 surviving. (limitations to this
methodology, as only small children could be supported this way and for
only a short period of time.)
• Soon thereafter, Richard DeWall, from Lillehei's laboratory, developed
the bubble oxygenator. A third type of oxygenator, was developed by
Kay and Cross in Cleveland and was being mass produced.
History
Definition
Cardiopulmonary bypass is a procedure to
circulate and oxygenate the blood while
surgery is performed on the heart. It
involves diverting blood from the heart and
lungs through a heart/lung machine and
returning oxygenated blood to the aorta.
(AHA Encyclopedia)
Cardiopulmonary Bypass Goals
• Oxygination and carbon dioxide elimination
• Circulation of blood
• Systemic cooling and re-warming
• To facilitate a surgical intervention
• Provide a motionless field
• Provide a bloodless field
Indications
• Coronary artery Disease
• Congenital Heart Disease
• Valvular Heart Disease
• Vascular Disease (AA,DA)
• Heart Transplant
Cardiopulmonary Bypass Machine
Oxygenator
Cardioplegia Delivery
Cardioplegia Delivery
Cardiopulmonary Bypass Circulation
Cardiopulmonary Bypass Physiology
• Hemodilution
• Anticoagulation
• Hypothermia
• Flow rate & Blood Pressure
• Blood gas Control
Risk of Cardiopulmonary Bypass
• Duration of Bypass
• Age
• Cardiac function
Organs affected by Cardiopulmonary Bypass
• Heart
• Brain
• Kidneys
• Gastrointestinal tract
• Endocrine systems
Thank you

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Cardiopulmonary Bypass.pptx

  • 2. Content Outline • History • Definition • Cardiopulmonary Bypass goals • Indications • Cardiopulmonary Bypass Machine • Oxygenator • Cardioplegia Delivery • Cardiopulmonary Bypass Circulation • Cardiopulmonary Bypass Physiology • Risk of Cardiopulmonary Bypass • Organs affected by Cardiopulmonary Bypass
  • 3. History • With the advent of vascular techniques and refined tools, quite a few advances had been made—repair of coarctation, the Blalock-Taussig shunt for Tetralogy of Fallot, mitral valve fracture and many others. • September of 1952, Lewis and his colleagues at the University of Minnesota closed an atrial septal defect on a 5-year-old patient with Hypothermia and inflow occlusion were the mainstay of operating inside the heart for a few minutes • May of 1953 when Dr. John Gibbon corrected an atrial septal defect in a young woman at Jefferson Hospital in Philadelphia with the assistance of a true heart-lung machine.
  • 4. History • In 1955, using some modifications, Dr. John Kirklin operated on a series of 8 congenital cases with survival of 50%. at the Mayo Clinic. • Dr. C. Walton Lillehei was developing the technique of "controlled cross- circulation. This was a method by which a child was connected to his parent as a "biologic heart machine." Over a 2-year period, Lillehei was able to operate on 45 children, with 28 surviving. (limitations to this methodology, as only small children could be supported this way and for only a short period of time.) • Soon thereafter, Richard DeWall, from Lillehei's laboratory, developed the bubble oxygenator. A third type of oxygenator, was developed by Kay and Cross in Cleveland and was being mass produced.
  • 6. Definition Cardiopulmonary bypass is a procedure to circulate and oxygenate the blood while surgery is performed on the heart. It involves diverting blood from the heart and lungs through a heart/lung machine and returning oxygenated blood to the aorta. (AHA Encyclopedia)
  • 7. Cardiopulmonary Bypass Goals • Oxygination and carbon dioxide elimination • Circulation of blood • Systemic cooling and re-warming • To facilitate a surgical intervention • Provide a motionless field • Provide a bloodless field
  • 8. Indications • Coronary artery Disease • Congenital Heart Disease • Valvular Heart Disease • Vascular Disease (AA,DA) • Heart Transplant
  • 14. Cardiopulmonary Bypass Physiology • Hemodilution • Anticoagulation • Hypothermia • Flow rate & Blood Pressure • Blood gas Control
  • 15. Risk of Cardiopulmonary Bypass • Duration of Bypass • Age • Cardiac function
  • 16. Organs affected by Cardiopulmonary Bypass • Heart • Brain • Kidneys • Gastrointestinal tract • Endocrine systems

Editor's Notes

  1. Through a series of experiments in dogs, Gibbon and his team were able to develop an oxygenator with multiple series of stainless-steel screens.
  2. Through a series of experiments in dogs, Gibbon and his team were able to develop an oxygenator with multiple series of stainless-steel screens. Gibbon and his team first attempted using the heart-lung machine on a child with a presumed atrial septal defect. But the diagnosis was wrong, and the patient succumbed to a patent ductus arteriosus. The second attempt came on May 6, 1953 on an 18-year-old, Cecilia Bavolek. An atrial septal defect was repaired with a continuous suture while the patient was completely supported by the heart-lung machine for 26 minutes.
  3. Through a series of experiments in dogs, Gibbon and his team were able to develop an oxygenator with multiple series of stainless-steel screens. Gibbon and his team first attempted using the heart-lung machine on a child with a presumed atrial septal defect. But the diagnosis was wrong, and the patient succumbed to a patent ductus arteriosus. The second attempt came on May 6, 1953 on an 18-year-old, Cecilia Bavolek. An atrial septal defect was repaired with a continuous suture while the patient was completely supported by the heart-lung machine for 26 minutes.