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Flap Delay
Dr Okpako Isaac Oghenero
Senior Registrar Plastic and Reconstructive Surgery
UATH
15/06/2023
outline
• Introduction
• Definition
• Delay
• Flap
• Epidemiology
• Historical perspective
• Goal of delay
• Types
• Theories
• Mechanism of flap delay
• Preparation
• History
• Examination
• Investigation
• Monitoring
• Complications
• Prevention of complication
• Local experience
• Current trend
• References
Introduction
• Definition of terms
• Delay
• This is the phenomenon where random pattern flap survival is enhanced
• Flap
• This is a unit of tissue transferred from a donor site to a recipient site while
maintaining its innate blood supply
• Random pattern flap
• These are flaps that are raised without a named vessel they survive on the bases
of its subdermal plexus
Historical perspective
• The delay procedure has been used for several hundred years,
• However it was not until the early 1900s that the concept was recognized.
• Blair introduced the term “delayed transfer” in 1921
• In the 16th century Tagliacozzi delayed his upper arm flaps by making parallel
incisions through the skin and subcutaneous tissue overlying the biceps muscle.
• In 1965, using the pig model, Milton investigated the effectiveness of four
different methods of delaying a flap. He found that in developing a bipedicled
flap, the best form of delay was by making two incisions and undermining the
skin between the incisions.
Goal of delay
• The goal of a delayed flap is to
• enhance flap circulation,
• There by ensuring flap survival after
advancement, transposition, or
transplantation to a defect
• To increase the area of a flap
Types
• Medical and
• surgical
• Medical delay
• The use of drugs have been tried for
delays
• Their role has been quite questionable
with variable results
• Some examples of mediations used for
medical delay includes
• The use of
• angiogenic agents such as VEGF PDGF and
FGF
• Antispasmodic
• Alpha adregenic agents
• Beta agonist direct vasodilators
• Calcium channel blockers
• Anticoagulants
• Thrombolytics
• Antispasmodics
• Leukocyte aggregation and adhesion
inhibitors such as montelucast
Types of delay
• Surgical delay
• Standard delay
• Strategic delay
• Standard delay
• This is partial flap elevation achieved by
incision at the margins of the cutaneous
territory
• Strategic delay
• This is achieved by making incisions at
the border of the planned flap cutaneous
territory.
• The dissection is either deep to muscle
or fascia, depending on the flap type, to
reach pedicles entering the flap territory.
• These pedicles are divided and the
incision is closed
• Radiologic vessels embolization
Theories of delay
• Ischaemic theory
• This theory postulates that delay causes adaptive metabolic changes at the cellular level
making the delayed tissue to survive on less nutrient blood flow than required thereby
improving its adaptability and hence its survival after flap movement
• Increased vascularity theory
• This theory believes that delay improves blood vascularity to delayed tissues by opening
preexisting blood vessels and reorganization of blood flow to ischaemic areas (choke
vessels)
Mechanism of flap delay
1. Sympathectomy
2. Vascular reorganization
3. Reactive hyperemia
4. Acclimatization to hypoxia
5. Nonspecific inflammatory
reaction
Mechanism of flap delay
• After 10-24 hours ---- Decreased arterial supply;
congestion and edema; dilation of arterioles and
capillaries
• 1-3 days ----- Increased number and quality of
anastomoses
increased number of small vessels in pedicle
• 3-7 days ---- Reorientation of vessels along the long
axis of the flap; anastomoses created at 1-3 days now
functionally significant
• After 1 week ---- Circulation well established between
• After 2 weeks ---- Continuous maturation of
anastomoses
• FLAP DEVISION CAN THEN BE DONE AT DAY 10 TO 14
Preparation
• History
• Examination
• Investigation
• History
• Indication for the surgery
• Hx of comobodities such as smoking
peripheral vascular diseases,
diabetes mellitus, bleeding
dyscrasias,
• Hx of previous delay and outcomes
• Hx of drug allergies
Preparation
• Examination
• Anatomy of the defect needing
cover
• Anatomy of the flap
• Territories of angiosomes to be
incorporated (anatomic potential
and dynamic)
• Flap design
Preparation
• Investigation
• To confirm flap dimension
• Doppler
• Use of dye (fluorescene dye etc)
• Angiogram
• To prepare patient for surgery
• FBC, eucr, LFT, U/A, FBS,
Flap Monitoring
 Subjective and Physical Criteria:
• Clinical observation remains the
most effective method of flap
monitoring
Colour-
Capillary blanching and
Warmth can be unreliable
Surface temperature and
differential thermometry
 Photoelectric Assessment
Ultrasound Doppler
Laser Doppler
 Metabolic
• Transcutaneous oxygen tension
• Photoplethysmography
Complications
• Preliminary operation
• Increase cost
• Increased hospital stay
• Injury to the desired pedicle
• Flap necrosis
• May impair subsequent manipulation and flap insert
Prevention
• Adequate preoperative planning
• Proper flap design
• Proper identification of pedicles
• Good grasp of the anatomy
Local experience
• We have quite a number of
surgical delay done in this
hospital
• Most recent was a delay for
cross leg flap
Current trend
• More modern forms of flap
transfers have been developed
such as free flap among others
making delay phenomenon less
practiced where all expertise and
equipment are available
Conclusion
• Flap delay is a technique
developed for random pattern
flap to enhance flap size and
survival
Thank you
References
• Iranpour M, Khodarahmi A, Khodarahmi N, Shafiee M, Malekpourafshar R, Nakhaee N.
Montelukast for Medical Delay in Flap Surgery. World J Plast Surg. 2020 Jan;9(1):48-54. doi:
10.29252/wjps.9.1.48. PMID: 32190592; PMCID: PMC7068180.
• ynn L, Chiu- Collins M.D, Surgical delay: vascular delay. Encyclopedia of Otolaryngology, head and
neck surgery.2013
• Essentials of plastic surgery, 2nd edition
• Keynotes in plastic surgery
• Neligans volume 4: flaps pathophysiology and pharmacology
• Caitlin S., Thompson-Torgerson, Lacy A. et al. Altered mechanism of thermoregulatory
vasoconstriction in aged human skin. Pubmed 2008
• Daniel N, Rajan S, David P, et al. salvage of failed free flaps used in head and neck reconstruction.
Pubmed 2009
• image003-300x121.jpg (300×121) (cellulite-endermologie-center.com)

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Flap delay.pptx

  • 1. Flap Delay Dr Okpako Isaac Oghenero Senior Registrar Plastic and Reconstructive Surgery UATH 15/06/2023
  • 2. outline • Introduction • Definition • Delay • Flap • Epidemiology • Historical perspective • Goal of delay • Types • Theories • Mechanism of flap delay • Preparation • History • Examination • Investigation • Monitoring • Complications • Prevention of complication • Local experience • Current trend • References
  • 3. Introduction • Definition of terms • Delay • This is the phenomenon where random pattern flap survival is enhanced • Flap • This is a unit of tissue transferred from a donor site to a recipient site while maintaining its innate blood supply • Random pattern flap • These are flaps that are raised without a named vessel they survive on the bases of its subdermal plexus
  • 4. Historical perspective • The delay procedure has been used for several hundred years, • However it was not until the early 1900s that the concept was recognized. • Blair introduced the term “delayed transfer” in 1921 • In the 16th century Tagliacozzi delayed his upper arm flaps by making parallel incisions through the skin and subcutaneous tissue overlying the biceps muscle. • In 1965, using the pig model, Milton investigated the effectiveness of four different methods of delaying a flap. He found that in developing a bipedicled flap, the best form of delay was by making two incisions and undermining the skin between the incisions.
  • 5. Goal of delay • The goal of a delayed flap is to • enhance flap circulation, • There by ensuring flap survival after advancement, transposition, or transplantation to a defect • To increase the area of a flap
  • 6. Types • Medical and • surgical • Medical delay • The use of drugs have been tried for delays • Their role has been quite questionable with variable results • Some examples of mediations used for medical delay includes • The use of • angiogenic agents such as VEGF PDGF and FGF • Antispasmodic • Alpha adregenic agents • Beta agonist direct vasodilators • Calcium channel blockers • Anticoagulants • Thrombolytics • Antispasmodics • Leukocyte aggregation and adhesion inhibitors such as montelucast
  • 7. Types of delay • Surgical delay • Standard delay • Strategic delay • Standard delay • This is partial flap elevation achieved by incision at the margins of the cutaneous territory • Strategic delay • This is achieved by making incisions at the border of the planned flap cutaneous territory. • The dissection is either deep to muscle or fascia, depending on the flap type, to reach pedicles entering the flap territory. • These pedicles are divided and the incision is closed • Radiologic vessels embolization
  • 8. Theories of delay • Ischaemic theory • This theory postulates that delay causes adaptive metabolic changes at the cellular level making the delayed tissue to survive on less nutrient blood flow than required thereby improving its adaptability and hence its survival after flap movement • Increased vascularity theory • This theory believes that delay improves blood vascularity to delayed tissues by opening preexisting blood vessels and reorganization of blood flow to ischaemic areas (choke vessels)
  • 9. Mechanism of flap delay 1. Sympathectomy 2. Vascular reorganization 3. Reactive hyperemia 4. Acclimatization to hypoxia 5. Nonspecific inflammatory reaction
  • 10. Mechanism of flap delay • After 10-24 hours ---- Decreased arterial supply; congestion and edema; dilation of arterioles and capillaries • 1-3 days ----- Increased number and quality of anastomoses increased number of small vessels in pedicle • 3-7 days ---- Reorientation of vessels along the long axis of the flap; anastomoses created at 1-3 days now functionally significant • After 1 week ---- Circulation well established between • After 2 weeks ---- Continuous maturation of anastomoses • FLAP DEVISION CAN THEN BE DONE AT DAY 10 TO 14
  • 11. Preparation • History • Examination • Investigation • History • Indication for the surgery • Hx of comobodities such as smoking peripheral vascular diseases, diabetes mellitus, bleeding dyscrasias, • Hx of previous delay and outcomes • Hx of drug allergies
  • 12. Preparation • Examination • Anatomy of the defect needing cover • Anatomy of the flap • Territories of angiosomes to be incorporated (anatomic potential and dynamic) • Flap design
  • 13. Preparation • Investigation • To confirm flap dimension • Doppler • Use of dye (fluorescene dye etc) • Angiogram • To prepare patient for surgery • FBC, eucr, LFT, U/A, FBS,
  • 14. Flap Monitoring  Subjective and Physical Criteria: • Clinical observation remains the most effective method of flap monitoring Colour- Capillary blanching and Warmth can be unreliable Surface temperature and differential thermometry  Photoelectric Assessment Ultrasound Doppler Laser Doppler  Metabolic • Transcutaneous oxygen tension • Photoplethysmography
  • 15. Complications • Preliminary operation • Increase cost • Increased hospital stay • Injury to the desired pedicle • Flap necrosis • May impair subsequent manipulation and flap insert
  • 16. Prevention • Adequate preoperative planning • Proper flap design • Proper identification of pedicles • Good grasp of the anatomy
  • 17. Local experience • We have quite a number of surgical delay done in this hospital • Most recent was a delay for cross leg flap
  • 18. Current trend • More modern forms of flap transfers have been developed such as free flap among others making delay phenomenon less practiced where all expertise and equipment are available
  • 19. Conclusion • Flap delay is a technique developed for random pattern flap to enhance flap size and survival
  • 21. References • Iranpour M, Khodarahmi A, Khodarahmi N, Shafiee M, Malekpourafshar R, Nakhaee N. Montelukast for Medical Delay in Flap Surgery. World J Plast Surg. 2020 Jan;9(1):48-54. doi: 10.29252/wjps.9.1.48. PMID: 32190592; PMCID: PMC7068180. • ynn L, Chiu- Collins M.D, Surgical delay: vascular delay. Encyclopedia of Otolaryngology, head and neck surgery.2013 • Essentials of plastic surgery, 2nd edition • Keynotes in plastic surgery • Neligans volume 4: flaps pathophysiology and pharmacology • Caitlin S., Thompson-Torgerson, Lacy A. et al. Altered mechanism of thermoregulatory vasoconstriction in aged human skin. Pubmed 2008 • Daniel N, Rajan S, David P, et al. salvage of failed free flaps used in head and neck reconstruction. Pubmed 2009 • image003-300x121.jpg (300×121) (cellulite-endermologie-center.com)

Editor's Notes

  1. Vital Dye Measurements: Fluorescein, Indocyanine green (may be essential during planning)