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Pulmonary Infections
Pneumonia and Tuberculosis
http://www.youtube.com/watch?v=h6z7Af-ssxw
http://www.youtube.com/watch?v=2vGuCK_HOLQ
https://www.youtube.com/watch?v=SEhAFmtaOCY
https://www.youtube.com/watch?v=lhMCFGPqvJg
http://videocast.nih.gov/Summary.asp?File=15873&bhcp=1
Pneumonia and tbc
Pneumonia and tbc
Pneumonia and tbc
From most prevalent to least.
Pneumonia and tbc
http://www.medscape.com/viewarticle/850138?nlid=88129_801&src=wnl_edit_medp_infd&uac=53576BK&spo
n=3&impID=817799&faf=1
Does this change everything?
…or is it just a bad study?
Pneumonia and tbc
http://www.medscape.com/viewarticle/825416?nlid=58208_801&src=wnl_edit_medp_infd&uac=53576BK&spon=3
New Diagnostics + New Vaccines = New Way of Thinking?
Pneumonia and tbc
Pneumonia and tbc
Pneumonia and tbc
Pneumonia and tbc
Pneumonia and tbc
Pneumonia and tbc
Pneumonia and tbc
Pneumonia and tbc
Pneumonia and tbc
Pneumonia and tbc
Seen most often in HAP and HCAP
Pneumonia and tbc
Treat the stain, modify when sensitivity results are available
Pneumonia and tbc
Typical with aspiration. Treat the stain regardless of the culture
results!
Pneumonia and tbc
http://videocast.nih.gov/Summary.asp?File=15873&bhcp=1
Aspiration is probably the major cause of VAP
Pneumonia and tbc
What is Ventilator Associated Pneumonia?
…it’s where drug resistant organisms have their holidays!
Pneumonia and tbc
Severe pneumonia + pre-existing severe illness + drug resistant pathogen = poor prognosis
Pneumonia and tbc
Is VAP as preventable as catheter associated UTIs and central line
infections?
Pneumonia and tbc
The risk of aspiration increases with age.
Pneumonia and tbc
Streptococcus pneumoniae and aspiration cause at least half of the pneumonia cases in the elderly.
Pneumonia and tbc
Pneumonia and tbc
Much of the damage in viral pneumonia is due to the host response.
Pneumonia and tbc
Pneumonia and tbc
Pneumonia and tbc
Pneumonia and tbc
Pneumonia and tbc
Pneumonia and tbc
Pneumonia and tbc
Pneumonia and tbc
Pneumonia and tbc
Bacteremic staphylococcal pneumonia typically has multiple, diffuse, cavitating,
round lesions.
Pneumonia and tbc
Pneumonia and tbc
Pleural fluid can be demonstrated on a lateral decubitus
film
Pneumonia and tbc
Pneumonia and tbc
http://videocast.nih.gov/summary.asp?Live=10827
http://www.youtube.com/watch?v=bR86G-itrTQ
http://www.cdc.gov/tb/publications/factsheets/testing/igra.ht
m
Pneumonia and tbc
http://www.medscape.com/viewar
ticle/766529
http://www.medpagetoday.com/
MeetingCoverage/ERS/41477
Pneumonia and tbc
Pneumonia and tbc
http://www.idsociety.org/Install_and_use_the_a
pp/
Pneumonia and tbc
Summary of Testing Guidelines
Pneumonia and tbc
CURB-65 and PSSI Help Guide Treatment Decisions
Pneumonia and tbc
Treatment Summary
Pneumonia and tbc
Age is the most significant risk factor for pneumonia
Pneumonia and tbc
Pneumonia and tbc
The problem of pneumonia in the elderly is as old as medicine.
Pneumonia and tbc
So what can we do?
Pneumonia and tbc
ww.medpagetoday.com/InfectiousDisease/Pneumonia/53017?xid=nl_mpt_special_reports_2015-09-08&eun=g519
…and a meta-analysis supports steroid use.
Pneumonia and tbc
So what can we do...?
Pneumonia and tbc
Pneumococcal vaccine decreases pneumococci in children.
Pneumonia and tbc
...even in non-immunized children!
Pneumonia and tbc
Less carriage by kids means less disease in kids...
Pneumonia and tbc
...and in the elderly!
Pneumonia and tbc
In fact, the effect may be most dramatic for pneumonia in the elderly!
Pneumonia and tbc
There is little evidence that pneumococcal vaccine given to the elderly has any value.
Pneumonia and tbc
The best way to prevent pneumonia in adults may be to vaccinate kids against strep pneumoniae and influenza!
Pneumonia and tbc
http://health.usnews.com/health-news/articles/2015/09/10/other-peoples-flu-vaccines-help-shield-seniors-too-study
Influenza vaccination of non-elderly adults limits influenza in the elderly.
Pneumonia and tbc
Consider:
Pneumonia and tbc
If tuberculosis is suspected-get Infectious
Diseases involved immediately. The public
health and infection control implications are
gigantic!Insist on performing tuberculosis stains as
early as possible, the cost and bother are
always justifiable.
A day or two of excessive respiratory
isolation is far preferable to unnecessary
exposure of scores of people to tuberculosis.
http://en.wikipedia.org/wiki/Tuberculosis_management

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Hemostasis Physiology and Clinical correlations by Dr Faiza.pdfHemostasis Physiology and Clinical correlations by Dr Faiza.pdf
Hemostasis Physiology and Clinical correlations by Dr Faiza.pdf
 

Pulmonary Infections Guide

Editor's Notes

  1. Productive mucoid cough and fever. Elderly often do not present with fever> bad immune response. Congestive heart failure and kidney failure patients also do no present with fever. Elderly are a high risk group for pneumonia. Pleuritic chest pain> one sided. Pleura rubs against each other> need surfactant. “hurts when I breathe” Pneumonia> productive cough. Mycoplasma> fever and infiltrated dry cough. Common in people between 15 and 40. To dx pneumonia: need to see infiltrates on CXR. Pneumonia might be present for a couple weeks before infiltrates are seen on X-ray. (Atypical pneumonia)
  2. Atypical pneumonia: mycoplasma is most common (late appearance of infiltrates)
  3. Lists are from most common infectious agent to least. Children most often get viral pneumonia. Adults: streptococcus is typical. Everything else is atypical. Adenovirus causes colds. Some strains are potent and can cause viral pneumonia. Occurs in “mini outbreaks” within dorms, military barracks etc.
  4. Smokers typically get hemophilus influenzae CAP