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www.bcmj.org VOL. 52 NO. 9, NOVEMBER 2010 BC MEDICAL JOURNAL 447
ABSTRACT: While osteoarthritis re-
mains the most common indication
for total knee replacement, the num-
ber of primary total knee arthroplas-
ties performed annually has increas-
ed exponentially over the last 55
years. Outcomes have improved
with the use of careful preoperative
assessment, a range of component
options, and operative technique
guided by clear surgical goals.
Informed consent of any patient con-
templating total knee arthroplasty
must be obtained by discussing the
risks and benefits and explaining that
between 80% and 85% of patients
are satisfied after the procedure.
M
ajor joint arthroplasty is
undoubtedly one of the
surgical success stories
of modern times. The
number of primary knee arthroplas-
ties performed annually increased
exponentially over the last half of the
20th century and increased between
16% and 44% during the first 5 years
of the 21st century.1,2 The history of
total knee arthroplasty began back
in 1860, when the German surgeon
Themistocles Gluck implanted the
first primitive hinge joints made of
ivory. Development really took off
following the introduction of the
Walldius hinge joint in 1951: initially
manufactured from acrylic and later,
in 1958, from cobalt and chrome.3
Unfortunately, this hinge joint suffer-
ed from early failure.
Intheearly1960s,JohnCharnley’s
cementedmetal-on-polyethylenetotal
hip arthroplasty inspired the develop-
ment of the modern total knee replace-
ment.4 Gunston, from the same centre
as Charnley, went on to design an
unhinged knee that replaced both the
medial and lateral sides of the joint
with separate condylar components.
Improvedbiomechanicsresultedfrom
the preserved intact cruciate and col-
lateral ligaments, which maintained
the stability of unlinked femoral and
tibial components, and a design that
allowedthecentreofrotationtochange
with flexion of the knee.5 The metal-
on-polyethylene condylar design—
completely replacing the femoral and
tibial articulating surfaces—was pur-
sued throughout the early 1970s at
centres across the world.6-11 The result
was an implant relying on component
geometry and soft tissue balance to
provide stability, with a large articu-
lating surface area to spread load and
minimize polyethylene wear. Incre-
mental improvements in component
materials, geometry, and fixation
continued throughout the 1970s and
1980s. More accurate sizing, the
option of patellafemoral replacement,
better instrumentation, and compo-
nents that allowed an increased range
of motion and a lower wear rate have
since been developed.
Unicompartmental knee arthro-
plasty developed in parallel with total
kneereplacementfromtheearlyefforts
Total knee arthroplasty:
Techniques and results
Providing a patient with a pain-free, stable knee joint that will last a
long time can be achieved by focusing on five surgical goals.
Daniel H. Williams, MSc, FRCS (Tr & Orth), Donald S. Garbuz, MD, MPH, FRCSC, B.A.
Masri, MD, FRCSC
Dr Williams is a fellow in the Division of
Lower Limb Reconstruction and Oncology
in the Department of Orthopaedics at
the University of British Columbia. Dr Gar-
buz is an associate professor and head of
the Division of Lower Limb Reconstruction
and Oncology in the Department of Ortho-
paedics at UBC. Dr Masri is a professor and
head of the Department of Orthopaedics at
UBC.
BC MEDICAL JOURNAL VOL. 52 NO. 9, NOVEMBER 2010 www.bcmj.org448
of McKeever and Elliott in 1952.12
However, because the unicompartmen-
tal procedure replaces only the dis-
eased part of the joint with more nat-
uralkinematicsorjointmovement,13,14
the indications for its use are more
limited.
Indications and
preoperative assessment
Osteoarthritis, whether primary, post-
traumatic, or secondary to avascular
necrosis, osteochondritis, or sepsis, is
by far the most common indication for
total knee replacement. Inflammatory
arthritides make up the bulk of the
remaining indications. Diagnosis of
the underlying condition allows appli-
cation of appropriate nonoperative
treatment, while the functional impact
of disease upon the everyday life of
the patient determines the appropriate
timing of surgery. Mechanical symp-
toms—locking or giving way—may
be amenable to arthroscopic assess-
ment and treatment. The severity of
symptoms are assessed by noting
reduced walking distance, analgesic
use, and sleep disturbance. Ability to
climb stairs or inclines, use of walk-
ing aids or other orthotics, and exac-
erbating or relieving factors all build a
more detailed picture of disability.
Knee examination should include
assessment of gait, surgical scars, loc-
alized tenderness, active and passive
range of motion, limb alignment, co-
ronal and sagittal plane ligament sta-
bility, and neurovascular status of the
limb. Other pathology contributing to
symptoms should be excluded by
examination of the back, hip, foot, and
ankle of the same limb.
Up-to-date and serial (if available)
radiographs of the knee should in-
clude an anteroposterior view as well
as true lateral and skyline patello-
femoral views of the involved knee
together with full long leg views if
there is significant deformity, previ-
ous fracture, or previous osteotomy of
the femur or tibia. An anteroposterior
pelvis and lateral radiograph of the
ipsilateralhipshouldbesoughtifthere
are symptoms of groin pain or signs of
stiffness or pain on rotation of the hip.
Magnetic resonance imaging can be
used to assess for meniscal or liga-
mentous injury in appropriate cases,
but is generally not required for the
routine assessment of the painful
arthritic knee. Radiographs should
always be performed before MRI is
ordered; in many cases, the plain rad-
iographic findings will make MRI
unnecessary.
The option of total knee arthro-
plasty is typically discussed with pa-
tients at the point in their lives when
knee pain from arthritis is significant-
ly interfering with activities of daily
living. Informed consent requires a
full discussion of the risks and bene-
fits of surgery to ensure that patient
expectations are realistic. Generally,
between 80% and 85% of patients are
satisfied with their knee arthroplasty.
The most significant complication is
deep infection, which complicates
between 1% and 2% of operations and
mayrequirefurtherandrepeatedmajor
joint surgery. Arterial injury compli-
cates between 0.03% and 0.17% of
cases15 and peroneal nerve injury has
been reported in between 0.3% and
2.0% of patients.16 The 20-day post-
operative mortality rate of 0.2% is
increased above the age-matched pop-
ulation and is the same as that meas-
ured for total hip arthroplasty. The
mortality rate normalizes with the
age-matched population after the 70th
postoperative day.17 Mortality at 1
year following knee arthroplasty is
1.6%, which is half the mortality rate
oftheage-matchedpopulation,demon-
strating that total knee arthroplasty
patients are a highly select group.18
Operative technique
Preoperative radiographic templating
for knee arthroplasty, while not as cru-
cial as for hip arthroplasty, does indi-
cate the size and shape of the tibial
bone to be removed and the compo-
nent type and size that is likely to be
required. It is particularly important
in cases requiring the extremes of
implant size to ensure that all likely
sizes are available, in cases of severe
deformity, and in cases where there is
severe bone loss.
Components
Most orthopaedic supply companies
manufacture a range of implant de-
signs, from cruciate ligament retain-
ing ( ) and posterior stabilized
( ) implants that usually pro-
vide sufficient stability in the primary
setting, through to megaprotheses for
replacing tumor or bone.
The level of built-in constraint, or
stability,requiredbyakneeprostheses
depends upon whether the posterior
cruciate and collateral ligaments are
intact. If the posterior cruciate liga-
ment is compromised, as it is in most
rheumatoid knees, or there is fixed
Figure 2
Figure 1
Total knee arthroplasty: Techniques and results
Radiographs should
always be performed
before MRI is ordered;
in many cases, the
plain radiographic
findings will make
MRI unnecessary.
www.bcmj.org VOL. 52 NO. 9, NOVEMBER 2010 BC MEDICAL JOURNAL 449
Total knee arthroplasty: Techniques and results
coronal plane or significant flexion
deformity, then the PCL is replaced
by a cam and post, the design of which
controls sagittal plane kinematics.
A larger post can provide additional
side-to-side/coronal plane stability
( ). If the medial collateral lig-
ament is compromised, a hinged pros-
thesis is chosen to further improve
coronal plane stability ( ). In-
evitably this puts greater strain upon
the hinge itself and produces increas-
ed shear stresses at the implant inter-
face with the bone. A rotating hinge
allows movement in the axial plane
between the polyethylene and tibial
surface, decreasing these stresses but
producing a secondary surface for the
generation of wear debris. Modular
femoral and tibial stems are added to
the resurfacing implants in this scen-
ario to increase the area of fixation,
spreading load and decreasing stress-
es at the implant bone interface.
Femoral or tibial stems of varying
lengths may also be added if there are
significant uncontained bone defects.
Generally, a contained bony defect
with an intact cortical rim or an uncon-
tained defect of less than 5 mm can be
filled with cement upon implantation.
Contained defects greater than 5 mm
with an intact cortical rim can be treat-
ed with morcelized impaction bone
allografting. Uncontained defects re-
quire shaping to accommodate the
metal wedges that are added to the
implant. Larger defects are not com-
monly encountered in the primary set-
ting, but when present may require
bulk bone allograft. The addition of a
femoral or tibial stem provides addi-
tional stability and protects supple-
mented defects, minimizing the risk
of long-term implant subsidence.
Surgical goals
The clinical aims of knee arthroplasty
are to provide the patient with a pain-
free, stable joint that will last a long
Figure 4
Figure 3
Figure 1. Cruciate ligament retaining
implant.
Figure 2. Posterior stabilized implant. The
presence of a post (arrow) distinguishes this
design from the cruciate ligament retaining
design in Figure 1, which has no such post.
Figure 3. Posterior stabilized implant
with larger post (arrow) for improving
coronal plane stability.
Figure 4. Hinged implant for improving
coronal plane stability. The hinge is linked
into the femoral component as indicated by
the arrow.
BC MEDICAL JOURNAL VOL. 52 NO. 9, NOVEMBER 2010 www.bcmj.org450
time.Toachievethis,thesurgicalteam
focuses on five surgical goals:
• Mechanical alignment of the limb.
The proximal tibia and the distal
femur are cut so that the mechanical
axis of the limb—from the centre of
the hip to the centre of the ankle
joint—passes through the centre of
the knee arthroplasty. This ensures
that forces are transmitted equally
through each side of the new joint,
optimizing the lifetime of the joint.19
Aligning the limb correctly also pro-
vides the correct starting platform
for achieving subsequent surgical
goals.
• Joint line preservation. The depth of
bone removed from the tibia and the
femur should be equal to the height
of the respective components that
are implanted. By taking out what is
to be put back in, the position of the
original joint line is preserved. This
optimizes the function of the liga-
ments and muscles acting upon the
knee.
• Soft tissue balance in the coronal
plane. Balancing the knee to varus
and valgus stress maintains equal
load transmission through each side
of the knee. Following many years
of disease, deformity in the coronal
plane can become fixed by contrac-
ture of soft tissues. Osteoarthritis
most commonly leads to a varus
deformity and tight medial soft tis-
sues, which are released in the fol-
lowing order to attain satisfactory
balance:
1. Medial osteophyte removal.
2. Proximal subperiosteal stripping
of the deep medial collateral lig-
ament.
3. Posteromedial capsular release.
4. PCLsacrifice requiring the use of
a posterior stabilized component.
5. Distal tibial periosteal stripping
of the MCL (avoiding complete
release and subsequent valgus
instability).
Rheumatoid arthritis or lateral
femoral condyle hypoplasia can lead
to a valgus deformity that requires the
following releases to attain satisfac-
tory balance:
1. Lateral osteophyte removal.
2. Subperiosteal dissection of the lat-
eral joint capsule.
3. Lateral patellofemoral ligament
release.
4. “Pie crusting” of the iliotibial band
if tight in extension.
5. Popliteus release if tight in flexion.
6. PCL sacrifice requiring the use of a
posterior stabilized component.
7. Lateral collateral ligament release
from its femoral insertion (avoid-
ing complete release and subse-
quent varus instability).
• Balance of the flexion and extension
gaps in the sagittal plane. This re-
sults in the knee maintaining stabil-
ity throughout its full range of mo-
tion.Flexioninstabilityoccurswhen
the gap between the tibia and the
femur is wider in flexion than in
extension and must be corrected to
ensure the patient is asymptomatic.
Recurvatum or extension beyond
0 degrees may result from a “loose”
extension gap. A “tight” flexion or
extension gap may restrict the full
range of flexion or extension. Loss
of full range of motion at either
extreme can be disabling. Loss of
full flexion can make stair and hill
climbing difficult. Loss of full ex-
tension makes complete lockout of
the knee impossible and requires
prolonged quadriceps muscle en-
gagement—which is tiring for the
patient—when standing in one spot.
A tibiofemoral gap consistent
throughout a full range of motion
can be achieved by using an appro-
priately sized tibial insert combined
with a femoral component implant-
ed in the correct position.
• Q angle correction. This is the angle
between the quadriceps and the
patella tendon and is a function of
the positioning of the tibial, femoral,
and, if used, patella component. In
particular the femoral component
requires appropriate positioning in
all three planes to allow the patella
to track correctly.
Each of these goals may not nec-
essarily be addressed in strict order
during surgery. Indeed, some of the
steps involved during the procedure
may address more than one goal at the
same time. For instance, sizing and
positioning the femur ensures balance
of the flexion and extension gaps as
well as creating a Q angle that affords
correct patella tracking. What is vital
is that every goal be considered in
order to produce a pain-free, stable
joint that will last a long time.
The operation
Following complete preoperative
assessment and planning to ensure
correct implant availability, a typical
total knee arthroplasty would proceed
as follows:
• Intravenous antibiotics are given
well before inflation of a proximal
thigh tourniquet to 300 mm Hg.
• The skin is prepped and draped to
allow an adequate midline longitu-
dinal incision to access the knee
joint, usually via a medial parapatel-
lar approach.
• Part of the anterior fat pad, remnants
of the medial and lateral menisci,
the anterior cruciate ligament and
the PCL (if a posterior stabilized
implant is to be used) are excised.
Osteophytes are excised and the
proximal medial soft tissues are
released to allow visualization of the
edge of the medial tibial plateau and
forward subluxation of the tibia in
full flexion and external rotation.
Further preliminary soft tissue re-
leases are performed at this stage as
appropriate.
• The tibia is cut at 90 degrees to its
Total knee arthroplasty: Techniques and results
www.bcmj.org VOL. 52 NO. 9, NOVEMBER 2010 BC MEDICAL JOURNAL 451
mechanical axis using an extra-
medullary or intramedullary jig.
Tibial bone is removed from the
normal side of the joint to the same
depth—usually 10 mm—as the
height of the tibial component to be
implanted, with the aim of preserv-
ing the position of the original joint
line.
• The femoral intrameduallary canal
is entered and the appropriate jig
is used to cut the distal femur in
between 5 and 7 degrees of valgus
relative to the anatomical axis. This
ensures the bone is cut at 90 degrees
to the mechanical axis of the femur,
thus satisfying the first surgical
goal of knee arthroplasty. Femoral
boneisremovedtothesamedepth—
again, usually 10 mm—as the height
of the femoral component to be im-
planted, with the aim of preserving
the position of the original joint line.
• The extension gap is checked to
ensurea10-mmspacercanbeinsert-
ed. If it cannot, the tibia or femur, as
appropriate, are recut by an appro-
priate amount—usually 2 to 4 mm.
Overall alignment of the bony cuts
is checked to ensure the limb is
straight and the soft tissues balance
to varus and valgus stress. Further
adjustments of the bony cuts and
further soft tissue releases proceed
if required.
• The femoral size is measured (in
the anteroposterior and mediolateral
plane) and correct position of
the femoral cutting block in the
sagittal (anteroposterior transla-
tion), the coronal (mediolateral
translation), and axial plane (rota-
tion) is ensured.
• The posterior femoral condylar cut
is made to enable trialing of the 10-
mm spacer block at 90 degrees of
flexion to confirm that the flexion
gap matches the extension gap be-
tween the tibia and the femur.
• The remaining femoral bony cuts
are made to match the inside of the
femoral component, and a drill hole
is made in each condyle to accom-
modate the two femoral pegs.The
trial components are inserted with
the appropriate tibial spacer. The
patella is prepared if it requires
replacement, and is rechecked prior
to final implantation. The optimum
position of the tibial component is
marked and preparation of the tibial
keel is completed.
• The cancellous bone surface is clean-
ed and the real components cement-
ed with antibiotic-loaded cement.
Compressionisappliedwiththeknee
in extension through a trial insert.
Once the cement has hardened any
loose cement is removed and the
appropriate real polyethylene insert
is implanted.
• The tourniquet is released to con-
firm hemostasis. A single drain is
used and the retinacular-tendinous
layer is closed with interrupted sut-
ures.The subdermal tissues and skin
are closed and dressings applied.
Postoperative care
Two further intravenous doses of anti-
biotics are given to cover the first 24
hours. Low molecular weight heparin
or a similar suitable anticoagulant is
prescribed—according to patient risk
assessment—usually up until the 10th
day postoperatively to ensure optimal
thromboprophylaxis. The patient is
mobilized, fully weight bearing in the
majority of cases, as soon as the gross
effectsoftheanesthetichavewornoff.
Patients are encouraged to maximize
knee extension and flexion at every
stage of their recovery to ensure opti-
mal outcome. Exercises are commen-
ced to ensure full recovery of quadri-
ceps tone and strength and analgesia
is provided to ensure the best possible
results from physiotherapy. Discharge
from hospital is allowed when the
wound is dry and the patient is safe
ascending and descending stairs.
Sutures or skin clips are removed at
10 to 14 days. A walking aid may be
required for several weeks following
surgery. The literature supports driv-
ing from 8 weeks, so long as the pa-
tient is clear of opiod analgesia and
can perform an emergency stop.20 Fol-
low-up appointments are scheduled at
6 to 8 weeks, 1 year, 5 years, and every
subsequent fifth year thereafter. Earli-
er follow-up should be requested if
there is any sign of infection or other
significant concern. Over 85% of total
knee arthroplasty patients will recover
knee function following a general
rehabilitation protocol. The remain-
ing 15% of patients will have difficul-
Total knee arthroplasty: Techniques and results
The patient is mobilized, fully weight
bearing in the majority of cases, as
soon as the gross effects of the
anesthetic have worn off.
BC MEDICAL JOURNAL VOL. 52 NO. 9, NOVEMBER 2010 www.bcmj.org452
ty obtaining proper knee function sec-
ondarytosignificantpain,limitedpre-
operative motion, or the development
of arthrofibrosis. This subset of
patients will require a more specific
prolonged rehabilitation program that
may involve ongoing oral analgesia,
continued physical therapy, additional
diagnostic studies, and occasionally
manipulation. Controlling pain is the
mainstay of any such treatment plan.21
Results
The survivorship rate is the percent-
age of total knee arthroplasties that
have not been revised in any given
series of patients. It is generally the
most often quoted outcome in the joint
arthroplasty literature. Survivorship
is arguably the most useful outcome
when distinguishing between differ-
ent prosthetic designs and also helps
answer the patient question, “How
long will the knee last?”
The pioneers of total knee arthro-
plasty saw early failures that quickly
led to the use of more durable materi-
als, better fixation, and improved de-
sign.5-11 Published longer-term results
have shown markedly differing sur-
vivorship rates between more subtle
differences in arthroplasty design. In
a recent study looking at 3234 knee
arthroplasties performed between
survivorship rates of 100% at 10 years
are seen with the Miller-Galante II
knee, which was redesigned to solve
the high rate of patellofemoral compli-
cations seen with the Miller-Galante I
(which still had an 84.1% survivorship
rate at 10 years).28 Studies comparing
the results of different design options
manufactured by the same company
are now also available: the 10-year
Genesis knee results for the (posteri-
or) cruciate retaining knee reveal 97%
survival compared with the Genesis
posterior stabilized knee, which has
96%survival—aninsignificantdiffer-
ence.29 The results of unicompartmen-
tal knee arthroplasty have been as
good as total knee arthroplasty in pub-
lished individual series, with sur-
vivorship rates of 98% at 10 years.30,31
It is arguably the recent registry
data for newer generation knee im-
plants that apply most readily to the
average patient considering total knee
arthroplasty. The 8-year survivorship
rate for the eight most common knee
joints in current use in Norway is
between 89% and 95%1 and the 7-year
rate in Australia is 95.7%.2 Of note,
purely in terms of survival, these reg-
istries have found inferior results for
even the best-performing unicompart-
mental knee arthroplasties when these
are compared with total knee arthro-
plasty. The cumulative survival at 7
years for unicompartmental knees in
Australia is only 88.1% compared
with95.7%fortotalknees.1,2 Thismay
relate to issues of patient selection or
reflect the increased technical expert-
ise required for this procedure. Con-
version of unicompartmental knee
arthroplasty to total knee replacement
isrelativelystraightforward,soappro-
priate patients seeking a partial knee
replacement should not be discour-
aged by the slightly lower long-term
survivorship seen in registry data.
Several knee scores have been
developed to assess outcome follow-
Total knee arthroplasty: Techniques and results
1969 and 1995, 89% of the condylar
designs had survived 10 years and
between 78% and 89% had survived
15years.22 Survivorshiprates,however,
varied considerably among different
implant designs. The corresponding
rates for some, now discontinued,
designs in this same study were
between 43% and 63% at 10 years
and between 28% and 59% at 15
years.22 Further studies have confirm-
ed clinical survival of the total condy-
lar knee design of 94% at 15 years23
and between 77% and 91% at 21 to 23
years.24,25 For this reason the total
condylar design has endured. Perhaps
the best long-term published results
are for the Anatomic Graduated Con-
dylar (AGC) knee arthroplasty, the
success of which is attributed to a
straightforward design that utilizes
carefullymanufacturedmaterials.The
AGC knee has a published survivor-
ship rate of 98.9% in 4583 knees at 15
years26 and a rate of 97.8% in 7760
knees at 20 years—quite impressive
survivorship. The number of knees
that reach long-term follow-up in such
series are, however, often small; only
36 of the 7760 knees in this study
made it to the 20-year point.27
Medium-term follow-up is becom-
ing available on updated versions of
the total condylar design. Improved
Improved survivorship rates of 100% at
10 years are seen with the Miller-Galante II
knee, which was redesigned to solve the
high rate of patellofemoral complications
seen with the Miller-Galante I.
www.bcmj.org VOL. 52 NO. 9, NOVEMBER 2010 BC MEDICAL JOURNAL 453
ingtotalkneearthroplasty.Thesetools
produce numbers that correspond to
excellent, good, fair, or poor outcome.
For example 92% of knees were as-
sessed as good or excellent in one
study, with 1.6% fair and 6.5% poor.23
Between 96% and 98% of knees were
assessed as good or excellent in anoth-
er study.29 However, more recently it
has been shown that the views of sur-
geons and their patients regarding the
outcome of surgical interventions do
not always correlate well—especially
with respect to function and pain.
Patient questionnaires are thought to
better assess patient outcome, and in a
recent study 81.8% of 8095 patients
were satisfied, 11.2% (906 of 8095)
were unsure, and 7.0% (566 of 8095)
were not satisfied with their new knee
joint.32
With regard to younger patients
under the age of 55 years, a survivor-
ship rate of 96% of 93 knees was
observed at 10 years,33 and of 90% of
108 knees at 18 years;34 94% of pa-
tients in the latter study had good or
excellent function and all but two
patients had improvement in their
activity score postoperatively. Fur-
thermore, 24% regularly participated
in activities such as tennis, skiing,
bicycling, or strenuous farm or con-
struction work.34 This suggests that
the traditional practice of withholding
knee replacement until patients are
over 65 or over is not warranted, and
replacement should proceed when
clinically appropriate.
It was traditionally thought that
obese patients do not fare as well as
normal-weight patients following
joint replacement. Postoperative out-
come scores for obese patients, how-
ever, were found to be comparable to
scores for patients who were not obese
in one recent study. Furthermore,
given the lower preoperative scores
measured in the obese group, the over-
all improvement was actually greater
than in the normal-weight group.
Additionally, survivorship rates in
obese patients were not significantly
lower than in patients who were not
obese at 10 years follow-up.35 There
was, however, a greater proportion of
lucent lines seen on the radiographs
around the implants of the obese
patients23,35 and in the morbidly obese
the complication rates are higher and
the implant survivorship rate is lower.
The final objective measure of
outcome perhaps most relevant to the
individual patient is range of flexion.
This has gradually improved from a
mean of 99 degrees23 to between 114
and 117 degrees with newer genera-
tion designs.29 Postoperative range of
motion largely depends on the preop-
erative range of motion. Generally,
what the patient has before the opera-
tion is what the patient can expect to
achieve after surgery and rehabilita-
tion.36 Patients seeking knee replace-
ment should be counseled that their
postoperative knee will not be “nor-
mal,” but it will feel and function
much better than their preoperative
arthritic knee.
Conclusions
Osteoarthritis remains the most com-
mon indication for total knee arthro-
plasty. Fortunately, technical devel-
opments over the last half century
have resulted in 10-year survivorship
rates of 90% and higher, and between
80% and 85% of patients have been
satisfied with their total knee replace-
ment. Further incremental improve-
ments in knee arthroplasty engineer-
ing, implant design, and material
science will continue to improve bear-
ing surface tribology, implant fixa-
tion, and implant longevity. These
advances will all help meet the main
surgical goals of total knee arthro-
plasty: to correct limb alignment, pre-
serve joint line position, balance the
soft tissues in the coronal plane, bal-
ance the flexion/extension gap in the
sagittal plan, and create a Q angle that
facilitates satisfactory patella track-
ing. Preoperative assessment and
planning will also help meet these
goals by ensuring patient expectations
are realistic and informed consent has
been obtained after a full discussion
of the risks and benefits of surgery.
Competing interests
None declared.
References
1. The Norwegian Arthroplasty Register.
Report 2006. www.haukeland.no/nrl/
eng (accessed 15 August 2009).
2. The Australian National Joint Replace-
Total knee arthroplasty: Techniques and results
Survivorship rates in obese patients
were not significantly lower than in
patients who were not obese at
10 years follow-up.
BC MEDICAL JOURNAL VOL. 52 NO. 9, NOVEMBER 2010 www.bcmj.org454
mentRegistry.Annualreport2008.www
.dmac.adelaide.edu.au/aoanjrr (acces-
sed 15 August 2009).
3. Walldius B. Arthroplasty of the knee joint
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British Columbia Medical Journal - November 2010: Knee Arthroplasty

  • 1. www.bcmj.org VOL. 52 NO. 9, NOVEMBER 2010 BC MEDICAL JOURNAL 447 ABSTRACT: While osteoarthritis re- mains the most common indication for total knee replacement, the num- ber of primary total knee arthroplas- ties performed annually has increas- ed exponentially over the last 55 years. Outcomes have improved with the use of careful preoperative assessment, a range of component options, and operative technique guided by clear surgical goals. Informed consent of any patient con- templating total knee arthroplasty must be obtained by discussing the risks and benefits and explaining that between 80% and 85% of patients are satisfied after the procedure. M ajor joint arthroplasty is undoubtedly one of the surgical success stories of modern times. The number of primary knee arthroplas- ties performed annually increased exponentially over the last half of the 20th century and increased between 16% and 44% during the first 5 years of the 21st century.1,2 The history of total knee arthroplasty began back in 1860, when the German surgeon Themistocles Gluck implanted the first primitive hinge joints made of ivory. Development really took off following the introduction of the Walldius hinge joint in 1951: initially manufactured from acrylic and later, in 1958, from cobalt and chrome.3 Unfortunately, this hinge joint suffer- ed from early failure. Intheearly1960s,JohnCharnley’s cementedmetal-on-polyethylenetotal hip arthroplasty inspired the develop- ment of the modern total knee replace- ment.4 Gunston, from the same centre as Charnley, went on to design an unhinged knee that replaced both the medial and lateral sides of the joint with separate condylar components. Improvedbiomechanicsresultedfrom the preserved intact cruciate and col- lateral ligaments, which maintained the stability of unlinked femoral and tibial components, and a design that allowedthecentreofrotationtochange with flexion of the knee.5 The metal- on-polyethylene condylar design— completely replacing the femoral and tibial articulating surfaces—was pur- sued throughout the early 1970s at centres across the world.6-11 The result was an implant relying on component geometry and soft tissue balance to provide stability, with a large articu- lating surface area to spread load and minimize polyethylene wear. Incre- mental improvements in component materials, geometry, and fixation continued throughout the 1970s and 1980s. More accurate sizing, the option of patellafemoral replacement, better instrumentation, and compo- nents that allowed an increased range of motion and a lower wear rate have since been developed. Unicompartmental knee arthro- plasty developed in parallel with total kneereplacementfromtheearlyefforts Total knee arthroplasty: Techniques and results Providing a patient with a pain-free, stable knee joint that will last a long time can be achieved by focusing on five surgical goals. Daniel H. Williams, MSc, FRCS (Tr & Orth), Donald S. Garbuz, MD, MPH, FRCSC, B.A. Masri, MD, FRCSC Dr Williams is a fellow in the Division of Lower Limb Reconstruction and Oncology in the Department of Orthopaedics at the University of British Columbia. Dr Gar- buz is an associate professor and head of the Division of Lower Limb Reconstruction and Oncology in the Department of Ortho- paedics at UBC. Dr Masri is a professor and head of the Department of Orthopaedics at UBC.
  • 2. BC MEDICAL JOURNAL VOL. 52 NO. 9, NOVEMBER 2010 www.bcmj.org448 of McKeever and Elliott in 1952.12 However, because the unicompartmen- tal procedure replaces only the dis- eased part of the joint with more nat- uralkinematicsorjointmovement,13,14 the indications for its use are more limited. Indications and preoperative assessment Osteoarthritis, whether primary, post- traumatic, or secondary to avascular necrosis, osteochondritis, or sepsis, is by far the most common indication for total knee replacement. Inflammatory arthritides make up the bulk of the remaining indications. Diagnosis of the underlying condition allows appli- cation of appropriate nonoperative treatment, while the functional impact of disease upon the everyday life of the patient determines the appropriate timing of surgery. Mechanical symp- toms—locking or giving way—may be amenable to arthroscopic assess- ment and treatment. The severity of symptoms are assessed by noting reduced walking distance, analgesic use, and sleep disturbance. Ability to climb stairs or inclines, use of walk- ing aids or other orthotics, and exac- erbating or relieving factors all build a more detailed picture of disability. Knee examination should include assessment of gait, surgical scars, loc- alized tenderness, active and passive range of motion, limb alignment, co- ronal and sagittal plane ligament sta- bility, and neurovascular status of the limb. Other pathology contributing to symptoms should be excluded by examination of the back, hip, foot, and ankle of the same limb. Up-to-date and serial (if available) radiographs of the knee should in- clude an anteroposterior view as well as true lateral and skyline patello- femoral views of the involved knee together with full long leg views if there is significant deformity, previ- ous fracture, or previous osteotomy of the femur or tibia. An anteroposterior pelvis and lateral radiograph of the ipsilateralhipshouldbesoughtifthere are symptoms of groin pain or signs of stiffness or pain on rotation of the hip. Magnetic resonance imaging can be used to assess for meniscal or liga- mentous injury in appropriate cases, but is generally not required for the routine assessment of the painful arthritic knee. Radiographs should always be performed before MRI is ordered; in many cases, the plain rad- iographic findings will make MRI unnecessary. The option of total knee arthro- plasty is typically discussed with pa- tients at the point in their lives when knee pain from arthritis is significant- ly interfering with activities of daily living. Informed consent requires a full discussion of the risks and bene- fits of surgery to ensure that patient expectations are realistic. Generally, between 80% and 85% of patients are satisfied with their knee arthroplasty. The most significant complication is deep infection, which complicates between 1% and 2% of operations and mayrequirefurtherandrepeatedmajor joint surgery. Arterial injury compli- cates between 0.03% and 0.17% of cases15 and peroneal nerve injury has been reported in between 0.3% and 2.0% of patients.16 The 20-day post- operative mortality rate of 0.2% is increased above the age-matched pop- ulation and is the same as that meas- ured for total hip arthroplasty. The mortality rate normalizes with the age-matched population after the 70th postoperative day.17 Mortality at 1 year following knee arthroplasty is 1.6%, which is half the mortality rate oftheage-matchedpopulation,demon- strating that total knee arthroplasty patients are a highly select group.18 Operative technique Preoperative radiographic templating for knee arthroplasty, while not as cru- cial as for hip arthroplasty, does indi- cate the size and shape of the tibial bone to be removed and the compo- nent type and size that is likely to be required. It is particularly important in cases requiring the extremes of implant size to ensure that all likely sizes are available, in cases of severe deformity, and in cases where there is severe bone loss. Components Most orthopaedic supply companies manufacture a range of implant de- signs, from cruciate ligament retain- ing ( ) and posterior stabilized ( ) implants that usually pro- vide sufficient stability in the primary setting, through to megaprotheses for replacing tumor or bone. The level of built-in constraint, or stability,requiredbyakneeprostheses depends upon whether the posterior cruciate and collateral ligaments are intact. If the posterior cruciate liga- ment is compromised, as it is in most rheumatoid knees, or there is fixed Figure 2 Figure 1 Total knee arthroplasty: Techniques and results Radiographs should always be performed before MRI is ordered; in many cases, the plain radiographic findings will make MRI unnecessary.
  • 3. www.bcmj.org VOL. 52 NO. 9, NOVEMBER 2010 BC MEDICAL JOURNAL 449 Total knee arthroplasty: Techniques and results coronal plane or significant flexion deformity, then the PCL is replaced by a cam and post, the design of which controls sagittal plane kinematics. A larger post can provide additional side-to-side/coronal plane stability ( ). If the medial collateral lig- ament is compromised, a hinged pros- thesis is chosen to further improve coronal plane stability ( ). In- evitably this puts greater strain upon the hinge itself and produces increas- ed shear stresses at the implant inter- face with the bone. A rotating hinge allows movement in the axial plane between the polyethylene and tibial surface, decreasing these stresses but producing a secondary surface for the generation of wear debris. Modular femoral and tibial stems are added to the resurfacing implants in this scen- ario to increase the area of fixation, spreading load and decreasing stress- es at the implant bone interface. Femoral or tibial stems of varying lengths may also be added if there are significant uncontained bone defects. Generally, a contained bony defect with an intact cortical rim or an uncon- tained defect of less than 5 mm can be filled with cement upon implantation. Contained defects greater than 5 mm with an intact cortical rim can be treat- ed with morcelized impaction bone allografting. Uncontained defects re- quire shaping to accommodate the metal wedges that are added to the implant. Larger defects are not com- monly encountered in the primary set- ting, but when present may require bulk bone allograft. The addition of a femoral or tibial stem provides addi- tional stability and protects supple- mented defects, minimizing the risk of long-term implant subsidence. Surgical goals The clinical aims of knee arthroplasty are to provide the patient with a pain- free, stable joint that will last a long Figure 4 Figure 3 Figure 1. Cruciate ligament retaining implant. Figure 2. Posterior stabilized implant. The presence of a post (arrow) distinguishes this design from the cruciate ligament retaining design in Figure 1, which has no such post. Figure 3. Posterior stabilized implant with larger post (arrow) for improving coronal plane stability. Figure 4. Hinged implant for improving coronal plane stability. The hinge is linked into the femoral component as indicated by the arrow.
  • 4. BC MEDICAL JOURNAL VOL. 52 NO. 9, NOVEMBER 2010 www.bcmj.org450 time.Toachievethis,thesurgicalteam focuses on five surgical goals: • Mechanical alignment of the limb. The proximal tibia and the distal femur are cut so that the mechanical axis of the limb—from the centre of the hip to the centre of the ankle joint—passes through the centre of the knee arthroplasty. This ensures that forces are transmitted equally through each side of the new joint, optimizing the lifetime of the joint.19 Aligning the limb correctly also pro- vides the correct starting platform for achieving subsequent surgical goals. • Joint line preservation. The depth of bone removed from the tibia and the femur should be equal to the height of the respective components that are implanted. By taking out what is to be put back in, the position of the original joint line is preserved. This optimizes the function of the liga- ments and muscles acting upon the knee. • Soft tissue balance in the coronal plane. Balancing the knee to varus and valgus stress maintains equal load transmission through each side of the knee. Following many years of disease, deformity in the coronal plane can become fixed by contrac- ture of soft tissues. Osteoarthritis most commonly leads to a varus deformity and tight medial soft tis- sues, which are released in the fol- lowing order to attain satisfactory balance: 1. Medial osteophyte removal. 2. Proximal subperiosteal stripping of the deep medial collateral lig- ament. 3. Posteromedial capsular release. 4. PCLsacrifice requiring the use of a posterior stabilized component. 5. Distal tibial periosteal stripping of the MCL (avoiding complete release and subsequent valgus instability). Rheumatoid arthritis or lateral femoral condyle hypoplasia can lead to a valgus deformity that requires the following releases to attain satisfac- tory balance: 1. Lateral osteophyte removal. 2. Subperiosteal dissection of the lat- eral joint capsule. 3. Lateral patellofemoral ligament release. 4. “Pie crusting” of the iliotibial band if tight in extension. 5. Popliteus release if tight in flexion. 6. PCL sacrifice requiring the use of a posterior stabilized component. 7. Lateral collateral ligament release from its femoral insertion (avoid- ing complete release and subse- quent varus instability). • Balance of the flexion and extension gaps in the sagittal plane. This re- sults in the knee maintaining stabil- ity throughout its full range of mo- tion.Flexioninstabilityoccurswhen the gap between the tibia and the femur is wider in flexion than in extension and must be corrected to ensure the patient is asymptomatic. Recurvatum or extension beyond 0 degrees may result from a “loose” extension gap. A “tight” flexion or extension gap may restrict the full range of flexion or extension. Loss of full range of motion at either extreme can be disabling. Loss of full flexion can make stair and hill climbing difficult. Loss of full ex- tension makes complete lockout of the knee impossible and requires prolonged quadriceps muscle en- gagement—which is tiring for the patient—when standing in one spot. A tibiofemoral gap consistent throughout a full range of motion can be achieved by using an appro- priately sized tibial insert combined with a femoral component implant- ed in the correct position. • Q angle correction. This is the angle between the quadriceps and the patella tendon and is a function of the positioning of the tibial, femoral, and, if used, patella component. In particular the femoral component requires appropriate positioning in all three planes to allow the patella to track correctly. Each of these goals may not nec- essarily be addressed in strict order during surgery. Indeed, some of the steps involved during the procedure may address more than one goal at the same time. For instance, sizing and positioning the femur ensures balance of the flexion and extension gaps as well as creating a Q angle that affords correct patella tracking. What is vital is that every goal be considered in order to produce a pain-free, stable joint that will last a long time. The operation Following complete preoperative assessment and planning to ensure correct implant availability, a typical total knee arthroplasty would proceed as follows: • Intravenous antibiotics are given well before inflation of a proximal thigh tourniquet to 300 mm Hg. • The skin is prepped and draped to allow an adequate midline longitu- dinal incision to access the knee joint, usually via a medial parapatel- lar approach. • Part of the anterior fat pad, remnants of the medial and lateral menisci, the anterior cruciate ligament and the PCL (if a posterior stabilized implant is to be used) are excised. Osteophytes are excised and the proximal medial soft tissues are released to allow visualization of the edge of the medial tibial plateau and forward subluxation of the tibia in full flexion and external rotation. Further preliminary soft tissue re- leases are performed at this stage as appropriate. • The tibia is cut at 90 degrees to its Total knee arthroplasty: Techniques and results
  • 5. www.bcmj.org VOL. 52 NO. 9, NOVEMBER 2010 BC MEDICAL JOURNAL 451 mechanical axis using an extra- medullary or intramedullary jig. Tibial bone is removed from the normal side of the joint to the same depth—usually 10 mm—as the height of the tibial component to be implanted, with the aim of preserv- ing the position of the original joint line. • The femoral intrameduallary canal is entered and the appropriate jig is used to cut the distal femur in between 5 and 7 degrees of valgus relative to the anatomical axis. This ensures the bone is cut at 90 degrees to the mechanical axis of the femur, thus satisfying the first surgical goal of knee arthroplasty. Femoral boneisremovedtothesamedepth— again, usually 10 mm—as the height of the femoral component to be im- planted, with the aim of preserving the position of the original joint line. • The extension gap is checked to ensurea10-mmspacercanbeinsert- ed. If it cannot, the tibia or femur, as appropriate, are recut by an appro- priate amount—usually 2 to 4 mm. Overall alignment of the bony cuts is checked to ensure the limb is straight and the soft tissues balance to varus and valgus stress. Further adjustments of the bony cuts and further soft tissue releases proceed if required. • The femoral size is measured (in the anteroposterior and mediolateral plane) and correct position of the femoral cutting block in the sagittal (anteroposterior transla- tion), the coronal (mediolateral translation), and axial plane (rota- tion) is ensured. • The posterior femoral condylar cut is made to enable trialing of the 10- mm spacer block at 90 degrees of flexion to confirm that the flexion gap matches the extension gap be- tween the tibia and the femur. • The remaining femoral bony cuts are made to match the inside of the femoral component, and a drill hole is made in each condyle to accom- modate the two femoral pegs.The trial components are inserted with the appropriate tibial spacer. The patella is prepared if it requires replacement, and is rechecked prior to final implantation. The optimum position of the tibial component is marked and preparation of the tibial keel is completed. • The cancellous bone surface is clean- ed and the real components cement- ed with antibiotic-loaded cement. Compressionisappliedwiththeknee in extension through a trial insert. Once the cement has hardened any loose cement is removed and the appropriate real polyethylene insert is implanted. • The tourniquet is released to con- firm hemostasis. A single drain is used and the retinacular-tendinous layer is closed with interrupted sut- ures.The subdermal tissues and skin are closed and dressings applied. Postoperative care Two further intravenous doses of anti- biotics are given to cover the first 24 hours. Low molecular weight heparin or a similar suitable anticoagulant is prescribed—according to patient risk assessment—usually up until the 10th day postoperatively to ensure optimal thromboprophylaxis. The patient is mobilized, fully weight bearing in the majority of cases, as soon as the gross effectsoftheanesthetichavewornoff. Patients are encouraged to maximize knee extension and flexion at every stage of their recovery to ensure opti- mal outcome. Exercises are commen- ced to ensure full recovery of quadri- ceps tone and strength and analgesia is provided to ensure the best possible results from physiotherapy. Discharge from hospital is allowed when the wound is dry and the patient is safe ascending and descending stairs. Sutures or skin clips are removed at 10 to 14 days. A walking aid may be required for several weeks following surgery. The literature supports driv- ing from 8 weeks, so long as the pa- tient is clear of opiod analgesia and can perform an emergency stop.20 Fol- low-up appointments are scheduled at 6 to 8 weeks, 1 year, 5 years, and every subsequent fifth year thereafter. Earli- er follow-up should be requested if there is any sign of infection or other significant concern. Over 85% of total knee arthroplasty patients will recover knee function following a general rehabilitation protocol. The remain- ing 15% of patients will have difficul- Total knee arthroplasty: Techniques and results The patient is mobilized, fully weight bearing in the majority of cases, as soon as the gross effects of the anesthetic have worn off.
  • 6. BC MEDICAL JOURNAL VOL. 52 NO. 9, NOVEMBER 2010 www.bcmj.org452 ty obtaining proper knee function sec- ondarytosignificantpain,limitedpre- operative motion, or the development of arthrofibrosis. This subset of patients will require a more specific prolonged rehabilitation program that may involve ongoing oral analgesia, continued physical therapy, additional diagnostic studies, and occasionally manipulation. Controlling pain is the mainstay of any such treatment plan.21 Results The survivorship rate is the percent- age of total knee arthroplasties that have not been revised in any given series of patients. It is generally the most often quoted outcome in the joint arthroplasty literature. Survivorship is arguably the most useful outcome when distinguishing between differ- ent prosthetic designs and also helps answer the patient question, “How long will the knee last?” The pioneers of total knee arthro- plasty saw early failures that quickly led to the use of more durable materi- als, better fixation, and improved de- sign.5-11 Published longer-term results have shown markedly differing sur- vivorship rates between more subtle differences in arthroplasty design. In a recent study looking at 3234 knee arthroplasties performed between survivorship rates of 100% at 10 years are seen with the Miller-Galante II knee, which was redesigned to solve the high rate of patellofemoral compli- cations seen with the Miller-Galante I (which still had an 84.1% survivorship rate at 10 years).28 Studies comparing the results of different design options manufactured by the same company are now also available: the 10-year Genesis knee results for the (posteri- or) cruciate retaining knee reveal 97% survival compared with the Genesis posterior stabilized knee, which has 96%survival—aninsignificantdiffer- ence.29 The results of unicompartmen- tal knee arthroplasty have been as good as total knee arthroplasty in pub- lished individual series, with sur- vivorship rates of 98% at 10 years.30,31 It is arguably the recent registry data for newer generation knee im- plants that apply most readily to the average patient considering total knee arthroplasty. The 8-year survivorship rate for the eight most common knee joints in current use in Norway is between 89% and 95%1 and the 7-year rate in Australia is 95.7%.2 Of note, purely in terms of survival, these reg- istries have found inferior results for even the best-performing unicompart- mental knee arthroplasties when these are compared with total knee arthro- plasty. The cumulative survival at 7 years for unicompartmental knees in Australia is only 88.1% compared with95.7%fortotalknees.1,2 Thismay relate to issues of patient selection or reflect the increased technical expert- ise required for this procedure. Con- version of unicompartmental knee arthroplasty to total knee replacement isrelativelystraightforward,soappro- priate patients seeking a partial knee replacement should not be discour- aged by the slightly lower long-term survivorship seen in registry data. Several knee scores have been developed to assess outcome follow- Total knee arthroplasty: Techniques and results 1969 and 1995, 89% of the condylar designs had survived 10 years and between 78% and 89% had survived 15years.22 Survivorshiprates,however, varied considerably among different implant designs. The corresponding rates for some, now discontinued, designs in this same study were between 43% and 63% at 10 years and between 28% and 59% at 15 years.22 Further studies have confirm- ed clinical survival of the total condy- lar knee design of 94% at 15 years23 and between 77% and 91% at 21 to 23 years.24,25 For this reason the total condylar design has endured. Perhaps the best long-term published results are for the Anatomic Graduated Con- dylar (AGC) knee arthroplasty, the success of which is attributed to a straightforward design that utilizes carefullymanufacturedmaterials.The AGC knee has a published survivor- ship rate of 98.9% in 4583 knees at 15 years26 and a rate of 97.8% in 7760 knees at 20 years—quite impressive survivorship. The number of knees that reach long-term follow-up in such series are, however, often small; only 36 of the 7760 knees in this study made it to the 20-year point.27 Medium-term follow-up is becom- ing available on updated versions of the total condylar design. Improved Improved survivorship rates of 100% at 10 years are seen with the Miller-Galante II knee, which was redesigned to solve the high rate of patellofemoral complications seen with the Miller-Galante I.
  • 7. www.bcmj.org VOL. 52 NO. 9, NOVEMBER 2010 BC MEDICAL JOURNAL 453 ingtotalkneearthroplasty.Thesetools produce numbers that correspond to excellent, good, fair, or poor outcome. For example 92% of knees were as- sessed as good or excellent in one study, with 1.6% fair and 6.5% poor.23 Between 96% and 98% of knees were assessed as good or excellent in anoth- er study.29 However, more recently it has been shown that the views of sur- geons and their patients regarding the outcome of surgical interventions do not always correlate well—especially with respect to function and pain. Patient questionnaires are thought to better assess patient outcome, and in a recent study 81.8% of 8095 patients were satisfied, 11.2% (906 of 8095) were unsure, and 7.0% (566 of 8095) were not satisfied with their new knee joint.32 With regard to younger patients under the age of 55 years, a survivor- ship rate of 96% of 93 knees was observed at 10 years,33 and of 90% of 108 knees at 18 years;34 94% of pa- tients in the latter study had good or excellent function and all but two patients had improvement in their activity score postoperatively. Fur- thermore, 24% regularly participated in activities such as tennis, skiing, bicycling, or strenuous farm or con- struction work.34 This suggests that the traditional practice of withholding knee replacement until patients are over 65 or over is not warranted, and replacement should proceed when clinically appropriate. It was traditionally thought that obese patients do not fare as well as normal-weight patients following joint replacement. Postoperative out- come scores for obese patients, how- ever, were found to be comparable to scores for patients who were not obese in one recent study. Furthermore, given the lower preoperative scores measured in the obese group, the over- all improvement was actually greater than in the normal-weight group. Additionally, survivorship rates in obese patients were not significantly lower than in patients who were not obese at 10 years follow-up.35 There was, however, a greater proportion of lucent lines seen on the radiographs around the implants of the obese patients23,35 and in the morbidly obese the complication rates are higher and the implant survivorship rate is lower. The final objective measure of outcome perhaps most relevant to the individual patient is range of flexion. This has gradually improved from a mean of 99 degrees23 to between 114 and 117 degrees with newer genera- tion designs.29 Postoperative range of motion largely depends on the preop- erative range of motion. Generally, what the patient has before the opera- tion is what the patient can expect to achieve after surgery and rehabilita- tion.36 Patients seeking knee replace- ment should be counseled that their postoperative knee will not be “nor- mal,” but it will feel and function much better than their preoperative arthritic knee. Conclusions Osteoarthritis remains the most com- mon indication for total knee arthro- plasty. Fortunately, technical devel- opments over the last half century have resulted in 10-year survivorship rates of 90% and higher, and between 80% and 85% of patients have been satisfied with their total knee replace- ment. Further incremental improve- ments in knee arthroplasty engineer- ing, implant design, and material science will continue to improve bear- ing surface tribology, implant fixa- tion, and implant longevity. These advances will all help meet the main surgical goals of total knee arthro- plasty: to correct limb alignment, pre- serve joint line position, balance the soft tissues in the coronal plane, bal- ance the flexion/extension gap in the sagittal plan, and create a Q angle that facilitates satisfactory patella track- ing. Preoperative assessment and planning will also help meet these goals by ensuring patient expectations are realistic and informed consent has been obtained after a full discussion of the risks and benefits of surgery. Competing interests None declared. References 1. The Norwegian Arthroplasty Register. Report 2006. www.haukeland.no/nrl/ eng (accessed 15 August 2009). 2. The Australian National Joint Replace- Total knee arthroplasty: Techniques and results Survivorship rates in obese patients were not significantly lower than in patients who were not obese at 10 years follow-up.
  • 8. BC MEDICAL JOURNAL VOL. 52 NO. 9, NOVEMBER 2010 www.bcmj.org454 mentRegistry.Annualreport2008.www .dmac.adelaide.edu.au/aoanjrr (acces- sed 15 August 2009). 3. Walldius B. Arthroplasty of the knee joint using an acrylic prosthesis. Acta Orthop Scand 1953;23:121-131. 4. CharnleyJ.Arthroplastyofthehip.Anew operation. Lancet 1961;1(7187):1129- 1132. 5. Gunston FH. Polycentric knee arthro- plasty. Prosthetic simulation of normal knee movement. J Bone Joint Surg Br 1971;53:272-277. 6. Ranawat CS. History of total knee replacement. J South Orthop Assoc 2002;11:218-226. 7. Coventry MB, Finerman GA, Riley LH, et al. A new geometric knee for total knee arthroplasty. Clin Orthop Relat Res 1972; 83:157-162. 8. Freeman MA, Swanson SA, Todd RC. Total replacement of the knee using the Freeman-Swanson knee prosthesis. Clin Orthop Relat Res 1973;(94):153-170. 9. Insall JF, Ranawat CS, Scott WN, et al. Total condylar knee replacment: Prelimi- nary report. Clin Orthop Relat Res 1976;149-154. 10. Ranawat CS, Shine JJ. Duo-condylar total knee arthroplasty. Clin Orthop Relat Res 1973;(94):185-195. 11. Townley C, Hill L. Total knee replace- ment. Am J Nurs 1974;74:1612-1617. 12. McKeever DC. The classic: Tibial plateau prosthesis 1960. Clin Orthop Relat Res 2005;440:4-8. 13. Goodfellow J, O’Connor J. The mechan- ics of the knee and prosthesis design. J Bone Joint Surg Br 1978;60-B:358-369. 14.Marmor L. The modular knee. Clin Orthop Relat Res 1973;(94)242-248. 15. Smith DF, McGraw RW, Taylor DC, et al. Arterial complications and total knee arthroplasty. J Am Acad Orthop Surg 2001;9:253-257. 16. Lonner JH, Lotke PA. Aseptic complica- tions after total knee arthroplasty. J Am Acad Orthop Surg 1999;7:311-324. 17. Lie SA, Engesaeter LB, Havelin LI, et al. Early postoperative mortality after 67,548 total hip replacements: Causes of death and thromboprophylaxis in 68 hos- pitals in Norway from 1987 to 1999. Acta Orthop Scand 2002;73:392-399. 18. National Joint Registry [for England and Wales 2007]. www.njrcentre.org.uk (ac- cessed 13 September 2010). 19. Fang DM, Ritter MA, Davis KE. Coronal alignment in total knee arthroplasty: Just how important is it? J Arthroplasty 2009; 24:39-43. 20. Spalding TJ, Kiss J, Kyberd P, et al. Driv- er reaction times after total knee replace- ment. J Bone Joint Surg Br 1994;76:754- 756. 21. RanawatCS,RanawatAS,MehtaA.Total knee arthroplasty rehabilitation protocol: What makes the difference? J Arthro- plasty 2003;18:27-30. 22. PradhanNR,GambhirAF,PorterML.Sur- vivorship analysis of 3234 primary knee arthroplasties implanted over a 26-year period: A study of eight different implant designs. Knee 2006;13:7-11. 23. Ranawat CS, Flynn WF Jr, Saddler S, et al. Long-term results of the total condy- lar knee arthroplasty. A 15-year survivor- ship study. Clin Orthop Relat Res 1993; (286)94-102. 24. Rodriguez JA, Bhende HF, Ranawat CS. Total condylar knee replacement: A 20- year followup study. Clin Orthop Relat Res 2001;(388)10-17. 25. Pavone VM, Boettner FM, Fickert SM, et al. Total condylar knee arthroplasty: A long-term followup. Clin Orthop Relat Res 2001;(388):18-25. 26. Ritter MA, Berend ME, Meding JB, et al. Long-term followup of anatomic gradu- ated components posterior cruciate- retaining total knee replacement. Clin Orthop Relat Res 2001;(388):51-57. 27. Ritter MA. The Anatomical Graduated Component total knee replacement: A long-term evaluation with 20-year sur- vival analysis. J Bone Joint Surg Br 2009;91:745-749. 28. Berger RA, Rosenberg AG, Barden RM, et al. Long-term followup of the Miller- Galante total knee replacement. Clin Total knee arthroplasty: Techniques and results Orthop Relat Res 2001;(388):58-67. 29. Laskin RS. The Genesis total knee pros- thesis: A 10-year followup study. Clin Orthop Relat Res 2001;(388):95-102. 30. Berger RA, Meneghini RM, Jacobs JJ, et al. Results of unicompartmental knee arthroplasty at a minimum of ten years of follow-up. J Bone Joint Surg Am 2005;87:999-1006. 31. Murray DW, Goodfellow JW, O’Connor JJ. The Oxford medial unicompartmen- tal arthroplasty: A ten-year survival study. J Bone Joint Surg Br 1998;80:983-989. 32. Baker PN, van der Meulen JH, Lewsey JF, et al. The role of pain and function in determining patient satisfaction after total knee replacement. Data from the National Joint Registry for England and Wales. J Bone Joint Surg Br 2007; 89:893-900. 33. Ranawat CS, Padgett DF, Ohashi Y. Total knee arthroplasty for patients younger than 55 years. Clin Orthop Relat Res 1989;(248)27-33. 34. Diduch DR, Insall JN, Scott WN, et al. Total knee replacement in young, active patients. Long-term follow-up and func- tional outcome. J Bone Joint Surg Am 1997;79:575-582. 35. Griffin FM, Scuderi GR, Insall JN, et al. Total knee arthroplasty in patients who were obese with 10 years followup. Clin Orthop Relat Res 1998;(356)28-33. 36. Gatha NM, Clarke HD, Fuchs RF, et al. 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