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Role of Cell in the Body QUALITATIVE AND QUANTITATIVE ABNORMALITIES
CELL LINE MATURATION/DISEASES AT EACH STAGE
Abnormal Cells
• Alberts B, J. A. (2002). Lymphocytes and the Cellular
Basis of Adaptive Immunity. In J. A. Alberts B, Molecular
Biology of the Cell. 4th edition. (pp. 497-523). New York:
Garland Science. Retrieved from www.ncbi.nlm.nih.gov
• Mayo Clinic Staff. ( 2012, September 15). Mayo Clinic.
Retrieved from Acute lymphocytic leukemia:
http://www.mayoclinic.org/diseases-conditions/acute-
lymphocytic-leukemia/basics/tests-diagnosis/con-
20042915
• Territo, M. (2013, January 1). Lymphocytic Leukocytosis.
Retrieved from www.merckmanuals.com:
http://www.merckmanuals.com/home/blood_disorders/
white_blood_cell_disorders/lymphocytic_leukocytosis.h
tml
• Zhang, D. &. (2012, DECEMBER 8).
www.asheducationbook.org. Retrieved from Hematology
: http://.hematologylibrary.org/content/2012/1/652.full
Bibliography
Cytokines and Growth Factors
The cytokines used in
the T cell line includes,
GM-CSF, IL-2, IL-4, IL-6
and IL-7. These are
used from the
pluripotent stem cell
until the cell reaches
the T Lymphoblast
stage, then cell
development is antigen
driven.
Acute Lymphoblastic
Leukemia: increase of
the lymphoblast cells
in a peripheral smear.
Infectious
mononucleosis:
viral infection,
presence of 50%
lymphocytes with at
least 10% atypical
lymphocytes
Prolymphocytic
Leukemia: A type of
chronic lymphocytic
leukemia.
Bone Marrow Aspiration: Increase of mature
small lymphocytes indicates chronic lymphocytic
leukemia.
Peripheral Smear: Reactive Lymphocytes are a
clear indication of infections (particularly viral
and rickettsia infections, whooping-cough
(pertussis), bacterial infections in infants and
young children. infections in infants and young
CBC: If the number of T cells is abnormally
decreased, this is an indication of AIDS. In
conditions, such as infections and blood diseases,
there is an abnormal increase in T cells.
Neoplastic Chemistries:
Chronic lymphocytic leukemia
Other lymphoid leukemia’s
Lymphomas in leukemic phase
March 27, 2015

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T Lymph Poster

  • 1. Role of Cell in the Body QUALITATIVE AND QUANTITATIVE ABNORMALITIES CELL LINE MATURATION/DISEASES AT EACH STAGE Abnormal Cells • Alberts B, J. A. (2002). Lymphocytes and the Cellular Basis of Adaptive Immunity. In J. A. Alberts B, Molecular Biology of the Cell. 4th edition. (pp. 497-523). New York: Garland Science. Retrieved from www.ncbi.nlm.nih.gov • Mayo Clinic Staff. ( 2012, September 15). Mayo Clinic. Retrieved from Acute lymphocytic leukemia: http://www.mayoclinic.org/diseases-conditions/acute- lymphocytic-leukemia/basics/tests-diagnosis/con- 20042915 • Territo, M. (2013, January 1). Lymphocytic Leukocytosis. Retrieved from www.merckmanuals.com: http://www.merckmanuals.com/home/blood_disorders/ white_blood_cell_disorders/lymphocytic_leukocytosis.h tml • Zhang, D. &. (2012, DECEMBER 8). www.asheducationbook.org. Retrieved from Hematology : http://.hematologylibrary.org/content/2012/1/652.full Bibliography Cytokines and Growth Factors The cytokines used in the T cell line includes, GM-CSF, IL-2, IL-4, IL-6 and IL-7. These are used from the pluripotent stem cell until the cell reaches the T Lymphoblast stage, then cell development is antigen driven. Acute Lymphoblastic Leukemia: increase of the lymphoblast cells in a peripheral smear. Infectious mononucleosis: viral infection, presence of 50% lymphocytes with at least 10% atypical lymphocytes Prolymphocytic Leukemia: A type of chronic lymphocytic leukemia. Bone Marrow Aspiration: Increase of mature small lymphocytes indicates chronic lymphocytic leukemia. Peripheral Smear: Reactive Lymphocytes are a clear indication of infections (particularly viral and rickettsia infections, whooping-cough (pertussis), bacterial infections in infants and young children. infections in infants and young CBC: If the number of T cells is abnormally decreased, this is an indication of AIDS. In conditions, such as infections and blood diseases, there is an abnormal increase in T cells. Neoplastic Chemistries: Chronic lymphocytic leukemia Other lymphoid leukemia’s Lymphomas in leukemic phase March 27, 2015