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SUBMITTED TO:
Dr. FEROZA WATTOO
SUBMITTED BY:
WAQAS NAWAZ 11-arid-975
ZAHID NAZIR 11-arid-976
ZEESHAN AHMED 11-arid-978
BIOCHEMISTRY-101
 Large polar molecules such as
glucose and amino acids, cannot
diffuse across the phospholipid
bilayer. Also ions such as Na+ or
Cl- cannot pass.
 These molecules pass through
protein channels instead.
Diffusion through these
channels is called
FACILITATED DIFFUSION.
 Movement of molecules is still
PASSIVE just like ordinary
diffusion, the only difference is,
the molecules go through a
protein channel instead of
passing between the
phospholipids.
AS Biology, Cell membranes and Transport 4
 Gas exchange at the alveoli — oxygen from air to
blood, carbon dioxide from blood to air.
 Gas exchange for photosynthesis — carbon
dioxide from air to leaf, oxygen from leaf to air.
 Gas exchange for respiration — oxygen from
blood to tissue cells, carbon dioxide in opposite
direction.
 Transfer of transmitter substance —
acetylcholine from presynaptic to postsynaptic
membrane at a synapse.
 Osmosis — diffusion of water through a
semipermeable membrane.
AS Biology, Cell membranes and
Transport 6
AS Biology, Cell membranes and
Transport 7
Cell membrane
Inside cell Outside cell
Protein channel
AS Biology, Cell membranes and
Transport 8
Cell membrane
Inside cell Outside cell
Protein channel
diffusion
AS Biology, Cell membranes and
Transport 9
Cell membrane
Inside cell Outside cell
Protein channel
diffusion
EQUILIBRIUM
AS Biology, Cell membranes and
Transport 10
AS Biology, Cell membranes and
Transport 11
Two major groups of integral membrane
proteins are involved in facilitated
diffusion;
 Carrier proteins
 Ion Channels
Ion channels allow currents to be carried
across the membrane and are thus of
particular importance in the physiology of
excitable cells like neurons
 Bind a specific type of solute
 Discharges the solute
Certain of the hexose transporters, which transport
glucose and similar monosaccharides into and out of
cells
 Not really bind the solute
 Faster than by carrier proteins
 Contain a "gate" which is functions to control
the channel's permiability
facilitateddiffusion-121126035122-phpapp02 (1).pdf
facilitateddiffusion-121126035122-phpapp02 (1).pdf

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facilitateddiffusion-121126035122-phpapp02 (1).pdf

  • 1.
  • 2. SUBMITTED TO: Dr. FEROZA WATTOO SUBMITTED BY: WAQAS NAWAZ 11-arid-975 ZAHID NAZIR 11-arid-976 ZEESHAN AHMED 11-arid-978
  • 4.  Large polar molecules such as glucose and amino acids, cannot diffuse across the phospholipid bilayer. Also ions such as Na+ or Cl- cannot pass.  These molecules pass through protein channels instead. Diffusion through these channels is called FACILITATED DIFFUSION.  Movement of molecules is still PASSIVE just like ordinary diffusion, the only difference is, the molecules go through a protein channel instead of passing between the phospholipids. AS Biology, Cell membranes and Transport 4
  • 5.  Gas exchange at the alveoli — oxygen from air to blood, carbon dioxide from blood to air.  Gas exchange for photosynthesis — carbon dioxide from air to leaf, oxygen from leaf to air.  Gas exchange for respiration — oxygen from blood to tissue cells, carbon dioxide in opposite direction.  Transfer of transmitter substance — acetylcholine from presynaptic to postsynaptic membrane at a synapse.  Osmosis — diffusion of water through a semipermeable membrane.
  • 6. AS Biology, Cell membranes and Transport 6
  • 7. AS Biology, Cell membranes and Transport 7 Cell membrane Inside cell Outside cell Protein channel
  • 8. AS Biology, Cell membranes and Transport 8 Cell membrane Inside cell Outside cell Protein channel diffusion
  • 9. AS Biology, Cell membranes and Transport 9 Cell membrane Inside cell Outside cell Protein channel diffusion EQUILIBRIUM
  • 10. AS Biology, Cell membranes and Transport 10
  • 11. AS Biology, Cell membranes and Transport 11
  • 12. Two major groups of integral membrane proteins are involved in facilitated diffusion;  Carrier proteins  Ion Channels Ion channels allow currents to be carried across the membrane and are thus of particular importance in the physiology of excitable cells like neurons
  • 13.  Bind a specific type of solute  Discharges the solute Certain of the hexose transporters, which transport glucose and similar monosaccharides into and out of cells
  • 14.  Not really bind the solute  Faster than by carrier proteins  Contain a "gate" which is functions to control the channel's permiability