This is powerpoint presentation of deep brain stimulators.

1. Deep brain stimulators
Prepared by-
Amreen. Abdul kadar.wadgama.
B-PHARM (FINAL)
S.N.I.O.PHARMACY PUSAD

2. CONTENTS
 INTRODUCTION
 IN TREATMENT OF
 COMPONENTS
 NEUROSURGICAL PROCEDURE
 BENIFITS
 COMPLICATION
 SURGERY AT UCLA

3. INTRODUCTION
• Deep brain stimulation (DBS) is a neurosurgical
procedure involving the implantation of
medical device called a Brain pacemaker.
• DBS sends electric impulses ,through implanted
electrodes ,to specific targets in the brain
which needs to be stimulated.
• DBS is not a cure, can stop the disease from
progressing, and even reverse it.

4. f
• Electrical probe implanted in brain
• Approved by FDA in mid 1990’s
• Hidden under skin (Differs depending
upon disorder being treated)
• Does not damage healthy tissue
• Improves motor function

5. DBS IN SELECTED BRAIN REGION FOR
TREATMENT OF-
• MOVEMENT AND NEUROPSYCHIATRIC
DISORDERS LIKE-
Parkinson’s disease.
Essential tremor.
Dystonia.
Chronic pain .
Major Depression.
Obsessive-compulsive disorder.

6. DEEP BRAIN STIMULATORS COMPONENT
Mainly consist of 3 component
• The Electrode-
Small tip shaped device.
Surface of electrode has 4 metal pads used to
transmit pulse of electricity.
Allows electrical stimulation to target only
brain (tissue) where electrodes are implanted.

7. THE-PULSE GENERATOR
• Also called as stimulator
• Small, box shaped
,generates electrical signals
sent to electrodes.
• Implanted under
skin(collar bone)
• It includes a battery (2to7
years)
• High frequencies gen (100
times/sec)

8. THE EXTENSION
• An insulated
cable carries
electric signal
from pulse
generator to
electrodes .

9. Implanted
pacemaker
Implanted wire
Electrode
Motor control brain
region

10. NEUROSURGICAL PROCEDURE
– Head frame is attached to skull
– Magnetic resonance imaging
(MRI) is done
– Burr hole is drilled in scalp
under local anaesthesia
– Electrode is inserted in brain .
– Implantable pulse generator
(IPG) is placed in collar bone .
– Connecting wire is attached .

11. ASLEEP DEEP BRAIN STIMUALATION
• Surgeries are performed with the patient
asleep.
AWAKE DEEP BRAIN STIMUALATION
• Surgeries are performed with the patient awake

12. BENEFITS
 Reduction in dyskinesia
 Suppression of medication-refractory tremor
 Simplification of medication regimen
 Reduction in medication dosage
 Improvement in performance of activities of
daily living
 Improvement in quality of life
 No lesions
 No destruction of the tissue

13. COMPLICATIONS
• RELATED TO THE SURGICAL PROCEDURE
Haemorrhage, ischemic lesions and
seizures
• ASSOCIATED WITH THE DEVICE
Electrode displacement, infection and
mechanical problems
• RELATED TO STIMULATION
Paraesthesia, muscle contraction, pain,
and abnormal eye movements, Worsening
dyskinesia

14. A NEUROSURGERY WITH GUITARIST !!!
• By neurosurgeon at
University of California at
Loss Angeles.
• Dated -10 JULY 2013
• & “stimulation helps to
restore a more normal
activity”
• To calm the tremors
associated with PD.

15. CONCLUSION
• Deep brain stimulation (DBS) is a
neurosurgical procedure.
• New hope for patients.
• Not a cure, can stop the disease from
progressing, and even reverse it.