Drugs acting on_CNS

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Aditi Kaushik

drugs acting on Central nervous system

Health & Medicine

Introduction
Drugs acting on CNS
Prepared By:
Aditi Kaushik
Assistant Professor
School of Pharmacy
MMU, Ambala

TYPES OF Drugs acting on CNS
CNS Stimulants
CNS Depressants

CNS STIMULANTS
The drugs which stimulate the motor and sensory
activities in the CNS.
Causes the potentiation and enhancement of excitatory
neurotransmission in CNS.
Inhibition of the inhibitory neurotransmission.
These drugs decrease the feeling of fatigue and causes
excitement.

Examples: A. Analeptics/ respiratory stimulants
B. Psychomotor stimulants
C. Methyl xanthines

CNS Depressants
The drugs which inhibit/ depress the motor and sensory
activities in the CNS.
Causes potentiation and enhancement of inhibitory
neurotransmission in CNS.
Inhibition of the excitatory neurotransmission.
These drugs calm CNS either by inducing sleep or without
inducing sleep.

Examples: A. Sedatives & Hypnotics
B. General anesthetics/ Local anesthetics
C. Anticonvulsants
D. Antiparkinsonism agents
E. Antipsychotics
F. Antidepressants
G. Opoid analgesics

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CNS Drugs CNS Drugs The drugs which act on the CNS(Central Nervous System) are known as CNS drugs The CNS consists of cerebrum, cerebellum, medulla and the spinal cord. CNS depressants The drugs which have a depressant action on the CNS Non selective depressants: which produce a generalised depressant action on the CNS. Eg. Hypnotic and sedative, central muscle relaxants Selective depressants: it selectively depress certain region or portion of the CNS. They include tranquillizers, Analgesics and anti-convalsants B. CNS stimulants the drugs which stimulate and reactivate CNS used for variety of purposes like treatment of depressive state, maintenance of wakefulness restoration of respiration and blood and restoration of normal reflexes. C. CNS modifiers(Tranquillizers) used in treatment of mental disorders. they produce improvement in the mood and behaviour of the patient Major tranquillizers: reduce the agitation and disturbed behaviour which are associated with delusion and hallucinations in schizophrenia Minor tranquillizers: there are antianxiety agents which gives calming effect in patients in anxiety state associated with neurotic personality This slide contains the definition of CNS drugs. Their classification based on chemical structure and PHARMACOLOGICAL ACTIVITY

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