Liquid based cytology is a method to collect and prepare cervical cell samples for microscopic examination. The sample is collected from the cervix using a spatula or broom and transferred to a preservative solution. The cells are then dispersed in the fluid and either centrifuged or filtered onto a slide to form a thin monolayer for staining and examination under a microscope. The two most widely used liquid based cytology systems are Sure Path and Thin Prep. Liquid based cytology offers advantages like immediate cell fixation, evaluation of all collected material, and preparation of representative samples, but it can alter smear patterns and dispersion of abnormal cells.