This lecture is about the basics of communicable diseases,like definitions,chain of infection or dynamics of diseases transmission and prevention and control measures about infectious diseases .
2. LEARNING OBJECTIVES:
ā¢ Definition of terminology related with communicable diseases.
ā¢ Classifications of communicable diseases.
ā¢ Surveillance and its types.
ā¢ Mechanism of disease transmission.
ā¢ Prevention and control of communicable diseases.
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3. COMMUNICABLE DISEASE
It may be defined as an:-
ļ āillness due to a specific infectious agent as its toxic products &
effects capable of being directly or indirectly transmitted from man to
man, animal to animal or from the environmentā i.e.(from
air,dust,soil,water,food etc)
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4. ļDISEASE:
o It is a physiological/psychological dysfunction. It is a condition in which body
health is impaired. This is an objective pathology of the body, such as an
infection.
ļILLNESS:
oA condition in which the equilibrium of the body is distrubed.The subjective
sense; the individual does not feel well & can not function as usual.
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ā¢IMPORTANT DEFINITIONS
5. ļFOLK ILLNESS:
o Syndromes from which members of a particular group claim to suffer;& for
which their culture provide their etiology, a diagnosis, preventive measures,&
regimens of healing.
ļSICKNESS:
oIt is a state of social dysfuntion.It is the condition of those who are socially
recognized as unwell.
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ā¢IMPORTANT DEFINITIONS
6. ā¢IMPORTANT DEFINITIONS
ļ¶INFECTION:
oThe process of introduction of microorganisms into human host followed by
their multiplication within the body at the expense of the host is called
infection.
ļ¶INFESTATION:
oIt is a state of having a parasite in or on the body which includes arthropods
or animal parasites.
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8. IMPORTANT DEFINITIONS(contā¦)
ļ¶EPIDEMIC: (epi=upon ,demos=people)
oAny disease injury or other health related events occurring suddenly in
members clearly in excess of normal expectancy
ā¢ E.g. cholera.
ļ¶ENDEMIC:(en=in, demos=people).
oIt refers to the constant presence of a disease or infectious agent within
a geographic area or population group without importation from
outside.
ā¢ E.g. common cold
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9. IMPORTANT DEFINITIONS(contā¦)
ļ¶SPORADIC: (means scattered about).
oThe cases occur irregurally,haphazardly from time to time & generally
infrequently showing little or no connection with each other nor a
recognizable common source of infection.
ā¢ e.g.polio,tatnus,herpes zooster & meningococcal meningitis etc.
ļ¶PANDEMIC:
oAn epidemic usually affecting a large proportion of the population &
occurring over a wide geographic area such as a section of a nation, the entire
nation, a continent or the world.
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10. IMPORTANT DEFINITIONS(cont..)
ļ¶EXOTIC:
ā¢ Diseases which are imported into a country in which they do not otherwise occur.
ā¢ E.g. Rabies in UK.
ļ¶ZOONOSIS:
ā¢ An infection or infectious disease transmissible under natural condition from
vertebrate animals to man.
ā¢ E.g. Rabies,Plague,Hydatid diseases,Anthrax etc.
ļAnthropozoonosois:
ā¢ Infections transmitted to man from vertebrate animals.
ā¢ (Rabies,Plague,Hydatid disease, Anthrax etc).
ļZooanthroponoses:
ā¢ Infections transmitted from man to vertebrate animals.
ā¢ (Human TB in cattle).
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11. IMPORTANT DEFINITIONS(cont..)
ļ¶HOST:
ā¢ A person or other animal including birds & arthropods, that affords logement to
an infectious agent under natural condition is called Host.
ļPrimary (or) Definitive Host:
ā¢ Host in which parasite attains maturity or passes its sexual stage.
ā¢ E.g. mosquito in malaria, man in Filariasis.
ļSecondary(or)Intermediate Host:
ā¢ Host in which parasite is in a larval or asexual state.
ā¢ E.g. man in malaria, mosquito in Filariasis.
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12. ļObligate Host:
ā¢ It means the only host.
ā¢ E.g. man in measles & Typhoid fever.
ļDead End Host:
ā¢ The host is infected, but does not become functionally infectious,& thus does
not transmit on the infection.
ā¢ E.g. Rabies, Bubonic Plague, Tetanus.
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IMPORTANT DEFINITIONS(cont..)
13. IMPORTANT DEFINITIONS(cont..)
ļ±INCUBATION PERIOD:
ā¢ The time interval b/w invasion by an infectious agent & appearance of the
first sign or symptom of the disease.
ļ±INFECTIVE PERIOD:
ā¢ The time interval during which an infectious agent can be transmitted from a
reservoir (patient) to the susceptible host.
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14. ļ±WINDOW PERIOD:
ā¢ The time b/w initial infection & the development of detectable antibodies
against the infection.
ļ±LATENCY PERIOD:
ā¢ The time from receiving the infection to the onset of infectiousness,i.e.the
ability to transmit infection.
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IMPORTANT DEFINITIONS(cont..)
15. IMPORTANT DEFINITIONS(cont..)
ļ¶EXPOSURE PERIOD:
ā¢ The time during which an individual or a group is exposed to a source of
infection.
ļ¶GENERATION TIME:
ā¢ The interval of time b/w receipt of infection by a host & maximal
infectivity/communicability of that host.
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16. ļ¶INFECTIVITY:
ā¢ Capacity of organisms to multiply in or around the host.
ļ¶PATHOGENICITY:
ā¢ Capacity to cause disease in an infected host.
ļ¶VIRULENCE:
ā¢ The ability of a microorganism to produce disease in a shorter period of time
with a very low dose even.
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IMPORTANT DEFINITIONS(cont..)
17. COMMUNICABLE DISEASE(contā¦)
ļ¶ INFECTIOUS DISEASE:
ā¢ A clinically manifest disease of man or animals resulting from an infection
ā¢ E.g.cholera,measles,T.B,chickenpox etc.
ļ¶ CONTAGIOUS DISEASE:
ā¢ A disease that is transmitted through contact.
ā¢ E.g. Scabies,Leprosy,STDs,Trachoma.
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18. COMMUNICABLE DISEASE(contā¦)
ļ¶IATROGENIC DISEASE:
ā¢ Any untoward or adverse consequence of a preventive, diagnostic or
therapeutic regimen or procedure, that comes imairment,handicap,disability
or death resulting from a physicianās professional activity or from the activity
of other health professionals.
ā¢ E.g.
I. Reactions to penicillin & immunizing agents.
II. Hepatitis B following blood transfusion.
III. Childhood leukemia due to prenatal X-Rays.
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19. COMMUNICABLE DISEASE(contā¦)
ļ¶NOSOCOMIAL INFECTION:
ā¢ It is a hospital acquired infection originating in a pt. while in a
hospital denoting a new disorder (unrelated to the ptās primary
condition).
ā¢ E.g.=Infection of surgical wounds,Hep:B & UTI .
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20. ļ¶CROSS INFECTION:
ā¢ When pts suffering from a particular disease are admitted in
hospital, they may acquire fresh infection from their neighbors
who may suffering from other disease.
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COMMUNICABLE DISEASE(contā¦)
21. ļ¶OPPORTUNISTIC INFECTION:
ļ§ This is infection by an organism(s) that takes the opportunity
provided by low resistance in host defense(e.g AIDS) to infect the
host &hence cause disease.
ā¢ E.g. Herpes simplex,CMV,Toxoplasma,TB.etc
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COMMUNICABLE DISEASE(contā¦)
28. CLASSIFICATION (contā¦)
CLASSIFICATION=2
I. Water washed Diseases.
II. Feco-oral diseases.
III. Soil mediated infections.
IV. Water contact diseases.
V. Skin infections
VI. Respiratory Infections.
VII. Diseases via body fluids.
VIII.Insect-Born Diseases.
IX. Ectoparasite Zoonosis.
X. Domestic Zoonosis.
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39. SURVELLANCE
ļ¶SURVELLANCE:
ā¢ āIt is the continuous & systemic collection, analysis & interpretation of health dataā
ā¢ āThe continuous scrutiny of the factors that determine the occurrence & distribution of
the disease & other conditions of ill-health ā
ā¢ It may be:
ļ 1.ACTIVE SURVEILLANCE:
ā¢ A reporter is contacted at regular intervals to specifically ask about the occurrence of diseases under
surveillance.
ļ 2.SENTINEL SURVEILLANCE:
ā¢ The reporting is from the sources(doctors ,hospitals ,etc) that are likely to see the cases of disease
under surveillance.
ļ 3.PASSIVE SURVEILLANCE:
ā¢ This is routine reporting in which the reporter initiates the case reports.
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41. TRANSMISSION OF INFECTIOUS DISEASE
Dynamicsofdisease
transmission:
1.Sourece &
Reservoir
2.Modes of
Transmission
3.Susceptible
host.
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42. TRANSMISSION OF INFECTIOUS DISEASE
ļ¶MECHANISM OF TRANMISSION/Dynamics of disease transmission:
ā¢ The mechanism of communicable disease transmission is mainly related to
āCHAIN OF INFECTION", it consist of;
1) Source & Reservoir,
2) Modes of Transmission,
3) Susceptible host.
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44. TRANSMISSION OF INFECTIOUS DISEASE(cont..)
ļ¶SOURCE:
ā¢ Is defines as the person,animal,object or substance from which an infectious
agent passes or is disseminated to the host.
ļ¶RESERVOIR:
ā¢ Is defined asā any person,animal,arthropod,plant,soil or substance (or
combination of these)ā in which an infectious agent lives & multiplies.
ļ¶Reservoir may be of three types:
A. Human reservoir
B. Animal reservoir
C. Reservoir in non-living things.
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45. TRANSMISSION OF INFECTIOUS DISEASE(cont..)
ļ¶HUMAN RESERVOIR:
ā¢ The important source or reservoir of infection for humans is a man himself.
ā¢ In human reservoir 2 things should be noted:-
I. CASES:
ļ§ May be defined as a person in the population or study group identified as having the
particular disease, health disorder or condition.
II. CARRIERS:
ļ§ A carrier is defined as an infected person or animal that harbors a specific infectious agent in
the absence of discrbile clinical disease & serve as a potential source of infection for others.
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46. CLASSIFICATION OF CARRIERS
A. By TYPE:
I. Incubatory Carriers: are those who shed the infectious agent during the
incubation period of disease E.g,measles, mumps, polio.
II. Convalescent Carriers:-are those who continue to shed the disease agent
during the convalescent period. E.g. typhoid fever, dysentery, cholera,
whooping cough, diphtheria.
III. Healthy Carriers:-are those who emerges from subclinical cases .The are
victims of subclinical infection who have developed carriers state without
suffering from overt disease. E.g. poliomyelitis, meningitis, cholera, diphtheria
& salmonellosis.
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47. CLASSIFICATION OF CARRIERS (contā¦)
B. By DURATION:
1.Temporary Carriers:
ļ§ Those who shed the infectious agent for short periods of time.
ā¢ It includes the incubatory, convalescent & healthy carriers.
2.Chronic Carriers:
ļ§ One who excretes the infectious agent for indefinite periods.
ā¢ E.g. typhoid fever, hepatitis B, gonorrhea, dysentery.
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48. CLASSIFICATION OF CARRIERS (contā¦)
C. By PORTAL OF EXIT:
ļ§ They are also classified as urinary, intestinal, respiratory, nasal carriers etc.
ļ§ Skin eruptions open wounds and blood are also portals of exit.
i. Urinary: typhoid, gonorrhea.
ii. Intestinal: cholera, typhoid.
iii. Respiratory: staphylococcal infection.
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49. RESERVOIR (cont..)
2. ANIMAL RESERVOIR:
ļ§ The source of infection may some times be animals and birds.
ļ§ The diseases & infections which are transmissible to men from
vertebrates is called Zoonosis.
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50. RESERVOIR (cont..)
3. RESERVOIR IN NON-LIVING THINGS:
ļ§ Soils & inanimate matter can also act as a reservoirs of infection.
ā¢ E.g. soil may harbors agents that cause tetanus, anthrax.
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52. MODES OF TRANSMISSION
ā¢ Communicable diseases may be transmitted from the reservoir or
source of infection to a susceptible individual in many different ways.
ā¢ The mode of transmission on infectious diseases may be classified as :
A. DIRECT TRANSMISSION.
B. INDIRECT TRANSMISSION.
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53. MODES OF TRANSMISSION (contā¦)
ā¢ DIRECT TRANSMISSION:
I. Direct contact
II. Droplet infection
III. Contact with soil
IV. Inoculation into skin or mucosa
V. Trans placental (vertical transmission)
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54. MODES OF TRANSMISSION (contā¦)
ā¢ INDIRECT TRANSMISSION
I. Vehicle borne
II. Vector borne (mechanical, biological)
III. Air borne (droplet nuclei, dust)
IV. Fomite
V. Unclean hands and fingers
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55. DIRECT TRANSMISSION
ā¢ DIRECT CONTACT:
ā¢ Infection may be transmitted by direct contact from skin to skin of the source
or others person .e.g. by touching, kissing or sexual intercourse.
ā¢ Diseases transmitted includes STD, AIDS, leprosy, skin & eye infection.
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56. DIRECT TRANSMISSION
ā¢ DROPLET INFECTION:
ā¢ This is due to the direct projection of a spray of droplets of saliva & nose
pharyngeal secretion during coughing & sneezing.
ā¢ Diseases transmitted by droplet spread includes many respiratory
infections. E.g. common cold, whooping cough & T.B.
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57. DIRECT TRANSMISSION
ā¢ CONTACT WITH SOIL:
ā¢ The disease agent may be in soil, compost or decaying vegetable matter.
ā¢ Examples of diseases, hook worm, tetanus, mycosis.
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58. DIRECT TRANSMISSION
ā¢ IN OCCULATION INTO SKIN AND MUCOSA:
ā¢ The disease agent may be inoculated directly into the skin or mucosa.
ā¢ E.g. rabies virus by dog bite, hepatitis B & C virus through contaminated needles and
syringes.
ā¢ TRANSPLACENTAL OR VERTICAL TRANSMISSION:
ā¢ In this case the disease agents can be transmitted transplacentally & is
another form of direct transmission.
ā¢ Examples are (TORCH)
ā¢ To= toxoplasma gondii
ā¢ R=rubella virus
ā¢ C= cytomegalo virus
ā¢ H=herpes virus
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59. INDIRECT TRANSMISSION
ā¢ This transmission includes the traditional 5Fās ā Flies, Fingers, Fomites, Food &
Fluidāā.
ā¢ VEHICLE BORNE
ā¢ It implies the transmission of the infectious agent through the agency of water,
food (including raw vegetables, fruits, milk & milk products)
ā¢ E.g. acute diarrhea, typhoid fever, cholera, polio, hep: A.
ā¢ VECTOR BORNE
ā¢ Vector is defined as an arthropod or any living carrier that transports an
infectious agent.
ā¢ Transmission by a vector may be mechanical or biological.
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60. ā¢ AIR BORNE:
ā¢ Droplet Nuclei:
ā¢ Are a type of particles implicated in the spread of air borne infections.
ā¢ They may be formed by:
ā¢ Evaporation of droplets of coughed or sneezed into the air, diseases include T.B, Influenza,
chicken pox, measles.
ā¢ DUST:
ā¢ Some of larger droplets which are expelled during talking, coughing & sneezing settles down
by their sheer weights on the floor , carpets, furniture, cloths etc
ā¢ A Variety of pathogenic bacteria, virus and fungal spores have been found in the dust of hospital
wards.
ā¢ Examples of diseases are pneumonia, T.B etc.
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INDIRECT TRANSMISSION
61. ā¢ Fomite borne, unclean hands &fingers:
ā¢ FOMITES includes:
ā¢ syringes, surgical dressings, towels, drinking glasses, spoons, soiled clothes, books,
cups, pencils, instruments etc.
ā¢ Diseases transmitted = diphtheria, hepatitis A, skin infections.
ā¢ UNCLEAN HANDS:
ā¢ Hands are the most common medium by which pathogen agents are transferred to food
from the bowl etc as well as from other foods.
ā¢ Examples are :
ā¢ -Staphylococcal infection
ā¢ -Typhoid & Para typhoid fever
ā¢ -Gastroenteritis
ā¢ -Dysentery
ā¢ -Hepatitis A
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INDIRECT TRANSMISSION
62. ā¢ Infectivity
ā¢ Pathogenicity
ā¢ Virulence
ā¢Immunogenicity
ā¢ Antigenicstability
ā¢ Survival
ā¢ Weather
ā¢ Housing
ā¢ Geography
ā¢ Occupational setting
ā¢ Air quality
ā¢ Food
Environment
ā¢ Age
ā¢ Sex
ā¢ Genotype
ā¢ Behaviour
ā¢ Nutritional status
ā¢ Health status
Host
Agent
Factors Influencing Disease Transmission
64. 3.SUSCEPTIBLE HOST.
ā¢ Susceptibility means a likelihood of a person getting a disease, for successful
transmission, the Infectious agent must have following stages:
i. The infectious agent must find a portal of entry.
ii. The organism must reach the appropriate tissues for its multiplication & survival.
iii. The disease agent must find a way out of the body to reach a new host(if there is
no portal of exit, the infection becomes a dead-end infection as in Rabies,
Bubonic plague & Tetanus).
iv. The organism must survive in the external environment for sufficient period till a
new host is found.
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66. PREVENTATION AND CONTROL OF THE COMMUNICABLE DISEASES
ā¢ The principle of prevention & control of diseases comes under following
headings:-
1. NOTIFICATION:-
ā¢ The immediate notice of this infection by the health officer as an authority. So
that they take measures for preventing the further spread of diseases.
2. EARLY DIAGNOSIS:-
ā¢ The physician must take a tentative diagnosis & advises isolation measures.
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67. PREVENTATION AND CONTROL OF THE COMMUNICABLE DISEASES (cont
3. ISOLATION:
ļ§ It is meant the separation of person suffering from communicable disease
from the rest of the family to prevent the transmission from the sick to the
healthy.
ā¢ QUARANTINE:-
ā¢ Isolation of healthy travelers (who do not possess any certificate of having
been immunized) from an infected area for at least the longest incubation
period of disease.
ā¢ DISEASE PERIOD OF QUARANTINE
ā¢ Cholera, plague, yellow fever 5days,6days,6day
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68. PREVENTATION AND CONTROL OF THE COMMUNICABLE DISEASES (cont..)
4.DESTRUCTION OF INFECTING AGENTS:-
ā¢ The destruction of pathogenic micro-organisms called disinfection & those
substances which destroy pathogenic material are called disinfectants, germicides
& bactericides.
5. INCREASING THE RESISTANCE OF THE SUSCEPTIBLE BY IMMUNIZATION:-
ā¢ It is very powerful measure for the control of communicable diseases & the
infection.
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69. PREVENTATION AND CONTROL OF THE COMMUNICABLE DISEASES (cont..)
6. BEHAVIORAL CHANGE:- (Health Education)
ā¢ Its purpose is to inform the community, about the principle of preventive
medicine & public health.
7. INVESTIGATION OF AN ATTACK OF ILLNESS:-
Responsibility of an health officer .
ā¢ To learn exact date of illness.
ā¢ To search the source of infection
ā¢ To search the history of any recent illness in the family or neighbors.
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