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1. Pathogenesis of Corona Virus:
Tissue tropism in man. They cause SevereAcute Respiratory Syndrome
(SARS). Corona virus family contains 11 recognizedwhich are divided into
five groups on basisof antigenic structure of N and M peplomer protein.
Corona viruses have tropism forrespiratory and gastrointestinal tract
epithelial cells.
Introduction to Corona:-
Viruses:Corona viruses (Corona,
meaning crown) arespherical (100-
150 nm indiam.),pleomorphicshape
d peplomers (spikes) on the surface.
CoVID-19 started infecting people
in the city of Wuhan, China in
mid-December of 2019. Within a
month, more than ten thousand
people were infected and
hundreds had died. The death
rate was about 16% in the first
two weeks but reduced to about
4% by mid-February and
currently stands at about 2%. The
initial outbreak caused many
people to die who would have
survived if they had received
medical treatment.
Unfortunately, the Wuhan
medical system was unable
to treat the extremely large
number of seriously ill
people seeking help. Simply
put, the large number of
seriously ill people greatly
exceeded hospital capacity.
Consequently, many people
who needed basic care for
dehydration and fever could
not find care. China now
reports a death rate of 0.7%
outside of Hubei Province.