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ECHOCARDIOGRAPHIC
EVALUATION OF AORTIC
STENOSIS
Dr. Kazi Abul Fazal Ferdous
IMO, CCU, DMCH
Normal Aortic valve
īļ Three cusps, crescent shaped 3
commissures 3 sinuses supported by
fibrous annulus
īļ3.0 to 4.0 cm2
2D Echo-Long axis view
Diastole Systole
2D Echo-Short axis view
Diastole Systole
Y or inverted Mercedes-Benz
2D - Apical five chamber view
2D – Suprasternal view
AORTIC STENOSIS
īļMost common :-
īƒ˜Bicuspid aortic valve with calcification
īƒ˜Senile or Degenerative calcific AS
īƒ˜Rheumatic AS
īļLess common:-
īƒ˜Congenital
īƒ˜Type 2 Hyperlipoproteinemia
EAE/ASE recommendations for Echocardiographic assessment of valve
stenosis, European Journal of Echocardiography 2009
CLASSIFICATION OF
AORTIC STENOSIS
Aortic sclerosis
īļ About 25% of all adults over age 65 yrs have aortic valve sclerosis.
īļ Thickened calcified cusps with preserved mobility.
īļ No significant obstruction to LV outflow.
īļ Typically associated with peak doppler velocity of < 2.5 m/sec.
īļ In Cardiovascular Health Study ,for group of patients â‰Ĩ 65
yrs,the aortic valve was normal in 70% of cases,sclerotic in 29% and
stenotic in 2%.
JACC.1997;29(3):630-4.
īļ In Euro Heart Survey of 4910 pts in 25 countries,AS was the most
frequent lesion,accounting for 43% of patients with VHD.
Eur Heart J.2003;24(13):1231-43.
Calcific Aortic Stenosis
īļ 10-15% of aortic sclerosis patients progress to severe
AS.
īļ Nodular calcific masses on aortic side of cusps.
īļ No commissural fusion.
īļ Free edges of cusps are not involve
īļ Stellate- shaped systolic orifice.
d.
Cosmi et al,Arch Int Med 2002;162(20):2345-7.
Calcific Aortic Stenosis
īļ Plax (Parasternal long axis) view
showing echogenic and immobile
aortic valve.
īļ Marked increase in echogenicity.
īļ Reduced systolic opening.
Calcific Aortic Stenosis
īļ Parasternal short-axis view
showing calcified aortic valve
leaflets. Immobility of the
cusps results in only a slit like
aortic valve orifice in systole.
īļ Used for valve area
(planimetry).
Imp points.
ī‚§ Directly planimetered aortic valve areas should be interpreted with
caution because of the complex anatomy of the orifice and calcific
shadowing and reverberation, even with 3D imaging.
ī‚§ Direct measurement of valve area on imaging reflects anatomic
valve area, whereas the doppler data provide functional area.
Bicuspid Aortic valve
Bicuspid Aortic Valve (BAV)
ī‚§ Accounts for 2/3rd of cases of severe AS in adults < 70 yrs.
ī‚§ 1/3rd of cases in adults > 70 yrs of age.
ī‚§ Severe AS of a BAV is difficult to be differentiated from that of
tricuspid one.
ī‚§ Usual view for differentiation is PARASTERNAL SHORT AXIS
VIEW at the level of great vessels in systole.
ī‚§ PARASTERNAL Long axis view shows systolic bowing of the
leaflets into aorta – “Dome like”.
ī‚§ M MODE – Eccentric closure line (to be taken at the tips of
bowed leaflets).
īļ Two cusps are seen in systole with only two commissures framing
an elliptical systolic orifice (the fish mouth appearance).
īļ Diastolic images may mimic a tricuspid valve when a raphe is
present.
Bicuspid Aortic valve
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Bicuspid Aortic valve
īļ In children, valve may be stenotic
without extensive calcification.
īļ In adults, stenosis typically is
due to calcific changes, which
often obscures the number of
cusps, making determination of
bicuspid vs. tricuspid valve
M mode of BAV
Types of BAV
FUSION OF
CUSPS
FREQUENCY LEAFLET
CLOSURE
LINE
REMARKS
RIGHT AND
LEFT
70 -80% Anterolateral –
posteromedial
closure line
Larger anterior
leaflet.
RIGHT AND
NONCORONARY
20-30% Anterior –posterior
closure line
Larger
rightward leaflet
LEFT AND
NONCORONARY
1-2% Medial – lateral
closure line
Many bicuspid aortic valves have a raphe in the larger leaflet.
Clear identification of number of leaflets is possible only in systole.
Schaefer et al ,Am J Cardiol 99(5);686-90.2007
Unicuspid aortic valve
ī‚§ Single eccentric orifice
ī‚§ Prominent systolic doming.
ī‚§ Acommisural
ī‚§ unicommisural
Quadricuspid aortic valve
īŽ RAKESH 40Y20150128153142738.avi
Subvalvular aortic stenosis
(1) Thin discrete membrane consisting of endocardial fold and fibrous
tissue.
(2) A fibromuscular ridge
(3) Diffuse tunnel-like narrowing of the LVOT
(4) Accessory or anomalous mitral valve tissue.
Young adults Valve not stenotic
But high gradients think of subvalvular
AS. TEE – confirmation.
Supravalvular Aortic stenosis
īļType I - Thick, fibrous ring above the aortic valve with less
mobility and has the easily identifiable 'hourglass' appearance
of the aorta.
īļ Type II - Thin, discrete fibrous membrane located above the aortic
valve
The membrane usually mobile and may demonstrate doming during
systole.
īļ Type III - Diffuse narrowing
Supravalvular Aortic stenosis
Rheumatic Aortic Stenosis
īļ Characterized by
īƒ˜ Commissural fusion
īƒ˜ Triangular systolic orifice
īƒ˜ Thickening & calcification
īļ Accompanied by rheumatic mitral valve changes.
īļ 30% of patients with MS,aortic valve is also affected in
RHD.
Rheumatic aortic stenosis
īļParasternal short axis view showing commissural
fusion, leaflet thickening and calcification, small
triangular systolic orifice
Differentiation of
Rheumatic vs Calcified AS
RHEUMATIC
AS
CALCIFIC AS
COMMISSURES FUSED FREE
LEAFLETS TIPS TO BASE BASE TO TIPS
ORIFICE TRIANGULAR STELLATE
SHAPEDAGE OF
PATIENT
NO
PARTICULAR
USUALLY
ELDERLYMITRAL
VALVE
30% OF MS CASES MAC +
OTHERS TIPS THICKENED,
CALCIFIED (INEXTREME)
TIPS ARE FREE (CALCIFIC
NODULES CAN BE
PRESENT not at TIPS)
M Mode- Normal aortic valve
īļ Maximal aortic cusp separation (MACS)
Vertical distance between right CC and non CC during systole
M Mode- Aortic Stenosis
Aortic valve area MACS Measurement Predictive value
Normal AVA >2Cm2 Normal MACS >15mm 100%
AVA>1.
0
> 12mm 96%
AVA<
0.75
< 8mm 97%
Gray area 8-12 mm â€Ļ..
DeMaria A N et al. Circulation.Suppl II.
M Mode- Aortic Stenosis
Limitations
ī‚§ Single dimension
ī‚§ Asymmetrical AV involvement
ī‚§ Calcification / thickness
↓ LV systolic functionī‚§
ī‚§ ↓ CO status
M Mode- Aortic Stenosis
M mode of Aortic valve in
LV dysfunction
HOCM
Sub aortic membrane
BAV
Calcific AS
Qualitative information of stenosis
by 2D echo
ī‚§ Thickened calcified cusps that display preserved mobility define
aortic sclerosis (peak doppler velocity of ≤ 2.5 m/sec).
ī‚§ Heavily calcified cusps with little or no mobility suggest severe
aortic
stenosis.
ī‚§ If one cusp is seen to move normally, critical aortic stenosis has
been excluded.ī‚§ Can lead to overestimation of
severity.
To be combined with doppler assessment.
A. Evaluate the anatomy of the
AV
EAE/ASE recommendations for Echocardiographic assessment of valve
stenosis, European Journal of Echocardiography 2009
ECHO EVALUATION OF AORTIC
STENOSIS
RCC
LCCNCC
DIASTOLE
SYSTOL
E
fusion of RCC
and NCC
fusion of
RCC and
LCC
ECHO EVALUATION OF AORTIC
STENOSIS
ECHO EVALUATION OF AORTIC
STENOSIS
ECHO EVALUATION OF AORTIC
STENOSIS
ECHO EVALUATION OF AORTIC
STENOSISB. Determine the aortic valve area by
Continuity Equation
EAE/ASE recommendations for Echocardiographic assessment of valve
stenosis, European Journal of Echocardiography 2009
ECHO EVALUATION OF AORTIC
STENOSISC. Determine the transaortic jet velocity
â€ĸmeasured using continuous-wave (CW) Doppler
Valvular Hear Disease, Chapter 63, Braunwarld’s Heart Disease 10th Edition
2014
ECHO EVALUATION OF AORTIC
STENOSIS
EAE/ASE recommendations for Echocardiographic assessment of valve
stenosis, European Journal of Echocardiography 2009
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Baseline echo
AVA: 0.96 cm2
PIG: 57mmHg
MG: 38 mmHg
EF 31%
PSEUDOSEVERE AORTIC STENOSIS
ī‚§will exhibit an increase in the AVA
ī‚§little change in transvalvular gradient in
response to the increase in transvalvular flow
rate
TRUE SEVERE AORTIC STENOSIS
â€ĸwill have no or minimal increase in
AVA
REST
ī‚§ AVA: 0.96cm2
ī‚§MG 38
ī‚§PIG: 57
ī‚§ EF: 31%
TRUE SEVERE AORTIC STENOSIS
LOW DOSE DOBU
ī‚§AVA: 0.99cm2
ī‚§MG: 51
ī‚§PIG: 76
ī‚§EF: 41% ( 32% inc)
Paradoxical Low flow Low gradient
ASâ€ĸ Elderly female
â€ĸ Associated with HTN,
DM
Echo Characteristicsâ€ĸ Severely thickened and calcified
AV
â€ĸ AVA < 1.0; MVG <40mmHg
â€ĸ EF â‰Ĩ 50%
â€ĸ Small LV cavity size (LVEDD
<47mm, LVEDV <55mL
â€ĸ RWT of >0.5
â€ĸ Impaired global longitudinal strain
<15% ASE’s Comprehensive Echocardiography 2nd ed ,
2016
ECHO EVALUATION OF AORTIC
STENOSISHemodynamic Progression
â€ĸannual decrease in valve area : 0.12 cm2/year
â€ĸannual increase in jet velocity of 0.32 m/sec/year
Follow-up Echo
â€ĸevery year: severe AS
â€ĸevery 1 to 2 years for moderate AS
â€ĸevery 3 to 5 years for mild AS.
Valvular Hear Disease, Chapter 63, Braunwarld’s Heart Disease 10th Edition
2014
THANK
YOU..

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Echocardiographic Assessment of Aortic Stenosis (EAOAS

  • 1. ECHOCARDIOGRAPHIC EVALUATION OF AORTIC STENOSIS Dr. Kazi Abul Fazal Ferdous IMO, CCU, DMCH
  • 2.
  • 3. Normal Aortic valve īļ Three cusps, crescent shaped 3 commissures 3 sinuses supported by fibrous annulus īļ3.0 to 4.0 cm2
  • 4.
  • 5.
  • 6.
  • 7. 2D Echo-Long axis view Diastole Systole
  • 8.
  • 9. 2D Echo-Short axis view Diastole Systole Y or inverted Mercedes-Benz
  • 10.
  • 11.
  • 12. 2D - Apical five chamber view
  • 13.
  • 15.
  • 16.
  • 17. AORTIC STENOSIS īļMost common :- īƒ˜Bicuspid aortic valve with calcification īƒ˜Senile or Degenerative calcific AS īƒ˜Rheumatic AS īļLess common:- īƒ˜Congenital īƒ˜Type 2 Hyperlipoproteinemia EAE/ASE recommendations for Echocardiographic assessment of valve stenosis, European Journal of Echocardiography 2009
  • 19. Aortic sclerosis īļ About 25% of all adults over age 65 yrs have aortic valve sclerosis. īļ Thickened calcified cusps with preserved mobility. īļ No significant obstruction to LV outflow. īļ Typically associated with peak doppler velocity of < 2.5 m/sec. īļ In Cardiovascular Health Study ,for group of patients â‰Ĩ 65 yrs,the aortic valve was normal in 70% of cases,sclerotic in 29% and stenotic in 2%. JACC.1997;29(3):630-4. īļ In Euro Heart Survey of 4910 pts in 25 countries,AS was the most frequent lesion,accounting for 43% of patients with VHD. Eur Heart J.2003;24(13):1231-43.
  • 20.
  • 21. Calcific Aortic Stenosis īļ 10-15% of aortic sclerosis patients progress to severe AS. īļ Nodular calcific masses on aortic side of cusps. īļ No commissural fusion. īļ Free edges of cusps are not involve īļ Stellate- shaped systolic orifice. d. Cosmi et al,Arch Int Med 2002;162(20):2345-7.
  • 22. Calcific Aortic Stenosis īļ Plax (Parasternal long axis) view showing echogenic and immobile aortic valve. īļ Marked increase in echogenicity. īļ Reduced systolic opening.
  • 23. Calcific Aortic Stenosis īļ Parasternal short-axis view showing calcified aortic valve leaflets. Immobility of the cusps results in only a slit like aortic valve orifice in systole. īļ Used for valve area (planimetry).
  • 24. Imp points. ī‚§ Directly planimetered aortic valve areas should be interpreted with caution because of the complex anatomy of the orifice and calcific shadowing and reverberation, even with 3D imaging. ī‚§ Direct measurement of valve area on imaging reflects anatomic valve area, whereas the doppler data provide functional area.
  • 25.
  • 26.
  • 28.
  • 29. Bicuspid Aortic Valve (BAV) ī‚§ Accounts for 2/3rd of cases of severe AS in adults < 70 yrs. ī‚§ 1/3rd of cases in adults > 70 yrs of age. ī‚§ Severe AS of a BAV is difficult to be differentiated from that of tricuspid one. ī‚§ Usual view for differentiation is PARASTERNAL SHORT AXIS VIEW at the level of great vessels in systole. ī‚§ PARASTERNAL Long axis view shows systolic bowing of the leaflets into aorta – “Dome like”. ī‚§ M MODE – Eccentric closure line (to be taken at the tips of bowed leaflets).
  • 30. īļ Two cusps are seen in systole with only two commissures framing an elliptical systolic orifice (the fish mouth appearance). īļ Diastolic images may mimic a tricuspid valve when a raphe is present. Bicuspid Aortic valve
  • 32. Bicuspid Aortic valve īļ In children, valve may be stenotic without extensive calcification. īļ In adults, stenosis typically is due to calcific changes, which often obscures the number of cusps, making determination of bicuspid vs. tricuspid valve
  • 33. M mode of BAV
  • 34. Types of BAV FUSION OF CUSPS FREQUENCY LEAFLET CLOSURE LINE REMARKS RIGHT AND LEFT 70 -80% Anterolateral – posteromedial closure line Larger anterior leaflet. RIGHT AND NONCORONARY 20-30% Anterior –posterior closure line Larger rightward leaflet LEFT AND NONCORONARY 1-2% Medial – lateral closure line Many bicuspid aortic valves have a raphe in the larger leaflet. Clear identification of number of leaflets is possible only in systole. Schaefer et al ,Am J Cardiol 99(5);686-90.2007
  • 35.
  • 36.
  • 37. Unicuspid aortic valve ī‚§ Single eccentric orifice ī‚§ Prominent systolic doming. ī‚§ Acommisural ī‚§ unicommisural
  • 38.
  • 39. Quadricuspid aortic valve īŽ RAKESH 40Y20150128153142738.avi
  • 40.
  • 41. Subvalvular aortic stenosis (1) Thin discrete membrane consisting of endocardial fold and fibrous tissue. (2) A fibromuscular ridge (3) Diffuse tunnel-like narrowing of the LVOT (4) Accessory or anomalous mitral valve tissue. Young adults Valve not stenotic But high gradients think of subvalvular AS. TEE – confirmation.
  • 42. Supravalvular Aortic stenosis īļType I - Thick, fibrous ring above the aortic valve with less mobility and has the easily identifiable 'hourglass' appearance of the aorta.
  • 43. īļ Type II - Thin, discrete fibrous membrane located above the aortic valve The membrane usually mobile and may demonstrate doming during systole. īļ Type III - Diffuse narrowing Supravalvular Aortic stenosis
  • 44. Rheumatic Aortic Stenosis īļ Characterized by īƒ˜ Commissural fusion īƒ˜ Triangular systolic orifice īƒ˜ Thickening & calcification īļ Accompanied by rheumatic mitral valve changes. īļ 30% of patients with MS,aortic valve is also affected in RHD.
  • 45. Rheumatic aortic stenosis īļParasternal short axis view showing commissural fusion, leaflet thickening and calcification, small triangular systolic orifice
  • 46. Differentiation of Rheumatic vs Calcified AS RHEUMATIC AS CALCIFIC AS COMMISSURES FUSED FREE LEAFLETS TIPS TO BASE BASE TO TIPS ORIFICE TRIANGULAR STELLATE SHAPEDAGE OF PATIENT NO PARTICULAR USUALLY ELDERLYMITRAL VALVE 30% OF MS CASES MAC + OTHERS TIPS THICKENED, CALCIFIED (INEXTREME) TIPS ARE FREE (CALCIFIC NODULES CAN BE PRESENT not at TIPS)
  • 47.
  • 48. M Mode- Normal aortic valve
  • 49.
  • 50. īļ Maximal aortic cusp separation (MACS) Vertical distance between right CC and non CC during systole M Mode- Aortic Stenosis Aortic valve area MACS Measurement Predictive value Normal AVA >2Cm2 Normal MACS >15mm 100% AVA>1. 0 > 12mm 96% AVA< 0.75 < 8mm 97% Gray area 8-12 mm â€Ļ.. DeMaria A N et al. Circulation.Suppl II.
  • 51. M Mode- Aortic Stenosis
  • 52. Limitations ī‚§ Single dimension ī‚§ Asymmetrical AV involvement ī‚§ Calcification / thickness ↓ LV systolic functionī‚§ ī‚§ ↓ CO status M Mode- Aortic Stenosis
  • 53. M mode of Aortic valve in LV dysfunction
  • 54. HOCM
  • 56. BAV
  • 58. Qualitative information of stenosis by 2D echo ī‚§ Thickened calcified cusps that display preserved mobility define aortic sclerosis (peak doppler velocity of ≤ 2.5 m/sec). ī‚§ Heavily calcified cusps with little or no mobility suggest severe aortic stenosis. ī‚§ If one cusp is seen to move normally, critical aortic stenosis has been excluded.ī‚§ Can lead to overestimation of severity. To be combined with doppler assessment.
  • 59. A. Evaluate the anatomy of the AV EAE/ASE recommendations for Echocardiographic assessment of valve stenosis, European Journal of Echocardiography 2009 ECHO EVALUATION OF AORTIC STENOSIS RCC LCCNCC DIASTOLE SYSTOL E
  • 60. fusion of RCC and NCC fusion of RCC and LCC ECHO EVALUATION OF AORTIC STENOSIS
  • 61. ECHO EVALUATION OF AORTIC STENOSIS
  • 62. ECHO EVALUATION OF AORTIC STENOSIS
  • 63. ECHO EVALUATION OF AORTIC STENOSISB. Determine the aortic valve area by Continuity Equation EAE/ASE recommendations for Echocardiographic assessment of valve stenosis, European Journal of Echocardiography 2009
  • 64. ECHO EVALUATION OF AORTIC STENOSISC. Determine the transaortic jet velocity â€ĸmeasured using continuous-wave (CW) Doppler Valvular Hear Disease, Chapter 63, Braunwarld’s Heart Disease 10th Edition 2014
  • 65. ECHO EVALUATION OF AORTIC STENOSIS EAE/ASE recommendations for Echocardiographic assessment of valve stenosis, European Journal of Echocardiography 2009
  • 66.
  • 71.
  • 72.
  • 73.
  • 74.
  • 76.
  • 77.
  • 80.
  • 81.
  • 82.
  • 84.
  • 85.
  • 86.
  • 87. Baseline echo AVA: 0.96 cm2 PIG: 57mmHg MG: 38 mmHg EF 31%
  • 88. PSEUDOSEVERE AORTIC STENOSIS ī‚§will exhibit an increase in the AVA ī‚§little change in transvalvular gradient in response to the increase in transvalvular flow rate
  • 89. TRUE SEVERE AORTIC STENOSIS â€ĸwill have no or minimal increase in AVA
  • 90. REST ī‚§ AVA: 0.96cm2 ī‚§MG 38 ī‚§PIG: 57 ī‚§ EF: 31% TRUE SEVERE AORTIC STENOSIS LOW DOSE DOBU ī‚§AVA: 0.99cm2 ī‚§MG: 51 ī‚§PIG: 76 ī‚§EF: 41% ( 32% inc)
  • 91. Paradoxical Low flow Low gradient ASâ€ĸ Elderly female â€ĸ Associated with HTN, DM Echo Characteristicsâ€ĸ Severely thickened and calcified AV â€ĸ AVA < 1.0; MVG <40mmHg â€ĸ EF â‰Ĩ 50% â€ĸ Small LV cavity size (LVEDD <47mm, LVEDV <55mL â€ĸ RWT of >0.5 â€ĸ Impaired global longitudinal strain <15% ASE’s Comprehensive Echocardiography 2nd ed , 2016
  • 92.
  • 93. ECHO EVALUATION OF AORTIC STENOSISHemodynamic Progression â€ĸannual decrease in valve area : 0.12 cm2/year â€ĸannual increase in jet velocity of 0.32 m/sec/year Follow-up Echo â€ĸevery year: severe AS â€ĸevery 1 to 2 years for moderate AS â€ĸevery 3 to 5 years for mild AS. Valvular Hear Disease, Chapter 63, Braunwarld’s Heart Disease 10th Edition 2014