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SBC322 Ecological and 
Evolutionary Genomics 
y.wurm@qmul.ac.uk
This changes 
454 
everything. 
Illumina 
Solid... 
Any lab can 
sequence 
anything!
How does this change affect us 
regarding ecology & evolution 
research?
Novel approaches for 
• relationships between species 
• relationships within species 
• species distributions 
• life histories 
• biodiversity assessments 
• evolutionary histories 
• identifying genes & mechanisms underlying 
• phenotypes (behaviors, morphologies, physiologies…) 
• constraints 
• responses to changing environments 
•…
Very exciting.
Aims (1/2) 
To understand and critically evaluate: 
• research questions 
• methods 
• experimental designs 
• applications 
in ecological and evolutionary genomics.
Aims (2/2) 
Improving skills: 
•critically reading scientific literature 
•understanding interdisciplinary science 
•oral scientific communication (formal & informal) 
•written scientific communication (blog & exam) 
Understanding: 
•the peer review process for scientific publication
Science-driven.
Interactive 
• Small groups - informal presentations 
• Formal presentations in pairs 
• Blog posts 
• Peer review
ok?
Yannick Wurm 
YW 
Christophe Eizaguirre 
CE
Main themes 
1. Methods 
2. Social evolution 
3. Conservation 
4. Genome dynamics 
5. Speciation
SBC322 Ecological and Evolutionary Genomics Schedule 23/09/Date Time Room Teaching Title 
1 2014-9-23 Tuesday 9:00 Eng. 3.24 YW Course overview + How to read a paper 
13:00 Eng. 3.25 YW Genomics Methods in Ecology & Evolution 
2 2014-9-30 Tuesday 9:00 Eng. 3.24 YW Genomics Methods explained (by you!) 
13:00 Eng. 3.25 YW Research papers: Theme 1 introduction 
3 2014-10-7 Tuesday 9:00 Eng. 3.24 YW Research papers Theme 1 explained (by you!) 
13:00 Eng. 3.25 CE Research Talk: Conservation Genomics in Turtles + Theme 2 introduction 
2014-10-9 Thursday 15:00 Scape 1.02 YW Methods recap (informal) & Organising blogging 
16:00 Scape 1.02 YW (continued) 
4 2014-10-14 Tuesday 9:00 Eng. 3.24 CE Informal Q&A session about the Theme 2 papers & presentations (only obligatory for presenters) 
13:00 Fogg 3.15 Labjolly 3.15 Research Talk: Invited Seminar - Andre Moura – University of Lincoln 
5 2014-10-21 Tuesday 9:00 Eng. 3.24 CE Research Papers Theme 2 - two student paper presentations (2 students per group) 
13:00 Eng. 3.25 YW Research Talk: Genome dynamics underlying social evolution + Theme 3 introduction 
6 2014-10-28 Tuesday 9:00 Eng. 3.24 YW Informal Q&A session about the Theme 2 papers & presentations (only obligatory for presenters) 
13:00 Eng. 3.25 CE Theme 2 - student paper presentations 
7 Reading week 
8 2014-11-11 Tuesday 9:00 Eng. 3.24 YW Research Papers Theme 2 - four student paper presentations (2 students per group) 
13:00 Eng. 3.25 YW (continued) 
2014-11-13 Thursday 15:00 Scape 1.02 CE Workshop: R class MHC and parasites for instance 
16:00 Scape 1.02 CE (continued) 
17:00 Scape 1.02 CE (continued) 
Week
Reading a paper 
Sequence of events: 
• Title 
• Abstract 
• Figures 
• Main text 
• (iterate)
Additional Guidelines 
• Read critically 
• authors aren’t always correct. 
• Instead, be suspicious 
• Read creatively 
• what are the good ideas? 
• what improvements could make important differences? 
• Make notes 
• underline/annotate/markup key points 
• questions/ambiguities/criticisms 
• After first read, summarise in 1-2 sentences 
• then extend summary 
• Compare to other works
Reading a paper / notes 
• a one or two sentence summary of the paper. 
• a deeper, more extensive outline of the main 
points of the paper, including for example 
assumptions 
• made, arguments presented, data analyzed, and 
conclusions drawn. 
• any limitations or extensions you see for the 
ideas in the paper. 
• your opinion of the paper; primarily, the 
quality of the ideas and its potential impact.
Methods papers

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2014 09-23-sbc322-intro

  • 1. SBC322 Ecological and Evolutionary Genomics y.wurm@qmul.ac.uk
  • 2.
  • 3. This changes 454 everything. Illumina Solid... Any lab can sequence anything!
  • 4. How does this change affect us regarding ecology & evolution research?
  • 5. Novel approaches for • relationships between species • relationships within species • species distributions • life histories • biodiversity assessments • evolutionary histories • identifying genes & mechanisms underlying • phenotypes (behaviors, morphologies, physiologies…) • constraints • responses to changing environments •…
  • 7. Aims (1/2) To understand and critically evaluate: • research questions • methods • experimental designs • applications in ecological and evolutionary genomics.
  • 8. Aims (2/2) Improving skills: •critically reading scientific literature •understanding interdisciplinary science •oral scientific communication (formal & informal) •written scientific communication (blog & exam) Understanding: •the peer review process for scientific publication
  • 10. Interactive • Small groups - informal presentations • Formal presentations in pairs • Blog posts • Peer review
  • 11. ok?
  • 12. Yannick Wurm YW Christophe Eizaguirre CE
  • 13. Main themes 1. Methods 2. Social evolution 3. Conservation 4. Genome dynamics 5. Speciation
  • 14.
  • 15. SBC322 Ecological and Evolutionary Genomics Schedule 23/09/Date Time Room Teaching Title 1 2014-9-23 Tuesday 9:00 Eng. 3.24 YW Course overview + How to read a paper 13:00 Eng. 3.25 YW Genomics Methods in Ecology & Evolution 2 2014-9-30 Tuesday 9:00 Eng. 3.24 YW Genomics Methods explained (by you!) 13:00 Eng. 3.25 YW Research papers: Theme 1 introduction 3 2014-10-7 Tuesday 9:00 Eng. 3.24 YW Research papers Theme 1 explained (by you!) 13:00 Eng. 3.25 CE Research Talk: Conservation Genomics in Turtles + Theme 2 introduction 2014-10-9 Thursday 15:00 Scape 1.02 YW Methods recap (informal) & Organising blogging 16:00 Scape 1.02 YW (continued) 4 2014-10-14 Tuesday 9:00 Eng. 3.24 CE Informal Q&A session about the Theme 2 papers & presentations (only obligatory for presenters) 13:00 Fogg 3.15 Labjolly 3.15 Research Talk: Invited Seminar - Andre Moura – University of Lincoln 5 2014-10-21 Tuesday 9:00 Eng. 3.24 CE Research Papers Theme 2 - two student paper presentations (2 students per group) 13:00 Eng. 3.25 YW Research Talk: Genome dynamics underlying social evolution + Theme 3 introduction 6 2014-10-28 Tuesday 9:00 Eng. 3.24 YW Informal Q&A session about the Theme 2 papers & presentations (only obligatory for presenters) 13:00 Eng. 3.25 CE Theme 2 - student paper presentations 7 Reading week 8 2014-11-11 Tuesday 9:00 Eng. 3.24 YW Research Papers Theme 2 - four student paper presentations (2 students per group) 13:00 Eng. 3.25 YW (continued) 2014-11-13 Thursday 15:00 Scape 1.02 CE Workshop: R class MHC and parasites for instance 16:00 Scape 1.02 CE (continued) 17:00 Scape 1.02 CE (continued) Week
  • 16.
  • 17. Reading a paper Sequence of events: • Title • Abstract • Figures • Main text • (iterate)
  • 18. Additional Guidelines • Read critically • authors aren’t always correct. • Instead, be suspicious • Read creatively • what are the good ideas? • what improvements could make important differences? • Make notes • underline/annotate/markup key points • questions/ambiguities/criticisms • After first read, summarise in 1-2 sentences • then extend summary • Compare to other works
  • 19. Reading a paper / notes • a one or two sentence summary of the paper. • a deeper, more extensive outline of the main points of the paper, including for example assumptions • made, arguments presented, data analyzed, and conclusions drawn. • any limitations or extensions you see for the ideas in the paper. • your opinion of the paper; primarily, the quality of the ideas and its potential impact.