Malaria originated in West and Central Africa and later spread worldwide. Approximately half of the world's population is at risk of contracting malaria, with most cases and deaths occurring in sub-Saharan Africa. Malaria has had devastating impacts on global populations, causing up to 1 million deaths annually, especially among young children in Africa. Looking to the future, efforts are underway to develop vaccines and continue distributing mosquito nets, but climate change may allow malaria to spread into new regions.