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Anesthesia Review
Anesthesia and Analgesia textbook
McCurnin’s Chapter 29: Veterinary
Anesthesia
Anesthesia - Terms
 Analgesia: pain relief.
 General anesthesia: unconsciousness and insensibility
to feeling and pain induced by administration of
anesthetic agents (given alone or in combination).
 Local anesthesia: loss of sensation in a localized body
part or region induced by administration of a drug or
other agent without the loss of consciousness.
 Premedication: administration of an agent(s) before
induction of general anesthesia to: calm/relax the patient,
ease induction + recovery, minimize adverse effects,
reduce amount of general anesthetic, muscle relaxation,
pain control.
Anesthesia – Terms
 Sedation: state of calm or drowsiness.
 Tranquilization: state of relaxation and reduced anxiety.
 Neuroleptanalgesia: state of profound sedation and
analgesia produced by simultaneous administration of an
opioid and a tranquilizer.
 Drug-based anesthetics: liquid agents injected into the
patient (or applied to a specific area – “local”) to induce
anesthesia (“general”).
 Inhalant anesthetic: liquid agents vaporized in oxygen
and administered via an anesthetic breathing system.
Patient Preparation
 Due to risk of nausea/vomiting caused by anesthetic
agents, patients must be fasted prior to anesthetic
procedures.
 Dogs and cats: withhold food for 8 – 12 hours prior,
water for 2 – 4 hours. Note: Neonates and patients <2kg
should NOT be fasted due to risk for hypoglycemia.
 Full patient history must be obtained.
 Complete physical exam must be performed: note ANY
and ALL abnormalities to the veterinarian.
 Diagnostic testing (at least CBC/Chem) should be
performed.
 Do not preemptively write up the anesthetic protocol for
a patient. Always consult with the veterinarian.
Protocol
 Anesthetic protocols will differ by veterinarian and
procedure type. Consult before calculating a protocol for
your patient.
 Considerations:
 Estimated length of procedure
 Patient age: neonates, geriatric
 Diagnostic testing results
 Patient’s demeanor: fractious, stoic, anxious
 Body condition score (BCS): obesity, cachexia
 Breed and species: Sighthounds, brachycephalic
 Overall patient health: high or extreme disease/risk factor such
as GDV, head trauma, organ failure, sepsis, internal
hemorrhage/rupture
Common Pre-medications
 Buprenorphine (Buprenex): partial agonist opioid; analgesic
and sedative. Effective in cats.
 Butorphanol (Torbugesic, Torbutrol): mixed agonist-
antagonist opioid; analgesic, sedative, and cough
suppressant. Effective in dogs when combined with
Acepromazine.
 Hydromorphone: agonist opioid; analgesia. Can cause
vomiting, nausea, hypersalivation, shivering.
 Naloxone: Reversal agent for opioids – have in stock! NOT
given as a pre-med, but rather, to reverse adverse effects of
opioids.
 Acepromazine: sedation ONLY. Cannot be reversed – use
with caution, especially in patients with seizure history. Used
as a pre-med only when combined with analgesic medications
Anesthetic Agents
 Alpha-2 Agonists:
 Often used for short, minimal procedures or in DKT
combination for fractious feline patient induction.
 Cause sedation, analgesia, and muscle relaxation.
 Side effects: severe bradycardia, hypotension, cardiac
arrhythmia, possible heart block.
 Examples:
 Dexmedetomidine (DexDomitor), reversed with
Atipamezole (Antisedan).
 Xylazine, reversed with Yohimbine.
Anesthetic Agents
 Propofol:
 Ultra-short-acting IV anesthetic: quick induction, quick
recovery.
 High end dose: 6mg/kg. Do not give entire dose IV: give
enough to intubate (“to effect”).
 Can cause transient excitement and apnea.
 Ketamine-Diazepam (“Ket-Val”):
 IV anesthetic combination = 1:1 volume ratio.
 Give entire dose IV slowly.
 Quick induction; prolonged recovery.
 Can cause hypersalivation and muscle tremors.
Controlled Drugs
 Some pre-meds and anesthetic agents are controlled
substances, but NOT all anesthetic drugs are considered
controlled drugs. Ex: alpha-2 agonists and Propofol do
not needed to be logged.
 The Controlled Substance Log in the hospital MUST
include:
 Date, owner’s and patient’s names, and address (or identification
number), starting volume, ending volume, amount used, and
initials/signature of the person who removed the drug from
inventory.
 The following veterinary drugs MUST be logged:
 Hydromorphone, Morphine, Buprenorphine, Butorphanol,
Ketamine, Fentanyl, Phenobarbital, Pentobarbital (Euthanasia
solution), Diazepam (Valium), Telazol, Hydrocodone.
Anesthetic Equipment
 Endotracheal tubes: placed inside the trachea of an
unconscious patient to administer oxygen and inhalant
anesthetic to the patient.
 Laryngoscopes: facilitate the placement of the
endotracheal tube; also allow for full oral cavity and
throat exam.
 Masks: used to administer oxygen and inhalant
anesthetic to patients that are NOT intubated.
 Anesthetic (Induction) Chambers: solid, see-through
boxes used to induce general anesthesia in fractious
patients.
 Anesthetic Machine: delivers oxygen and inhalant
anesthetic agents to patient (general anesthesia).
 LEAK TEST the machine every day prior to use!
Intubation
 Occurs after IV, IM or mask induction: have all supplies
ready!
 3 ET tubes (1 of the ideal size, 1 smaller, 1 larger), roll gauze to
tie in tube, gauze sponge to grasp tongue, cuff inflation syringe
(empty 6ml – 12ml), laryngoscope with appropriate sized blade,
0.1ml syringe of Lidocaine for feline laryngospasm (NO needle!).
 Size choices:
 Cats: 3.0 – 4.5mm
 Most small dogs: 5.0 – 6.5mm,
 Most medium dogs: 6.5 – 8.0mm,
 Most large dogs: 8.0 – 11.0mm
 Brachycephalic and obese patients: Always choose a smaller
tube than you would feel is appropriate.
Intubation
 Intubate gently, do not overinflate the cuff, and verify the
tube is not advanced too far past the thoracic inlet.
 Connect patient to anesthetic machine and turn on gas.
 Verify proper placement via auscultation of both sides of chest.
 Inflate the cuff
 Apply steady pressure to the reservoir bag while
simultaneously filling the cuff slowly.
 Stop inflating the cuff when you can no longer hear air escaping
from the lungs around the tube.
 Relieve pressure on the bag and make sure the pop-off valve is
open.
Intubation
 Possible Complications:
 Patient is waking up.
 Patient has a low pulse oximetry (hypoxia).
 Patient is not breathing properly.
 Verify the ET tube is placed properly:
 Measure the tube to verify it is not advanced too far down into one
of the mainstem bronchi (auscultate for breath sounds).
 Verify the tube is not too thin or too wide in diameter for the
patient’s throat size.
 Verify the cuff is appropriately inflated.
 Verify there is no air leaking from the anesthesia machine tubing
into your patient = “leak check”.
Anesthetic Machines
 Parts of the machine:
 Oxygen supply: can either be E- or H-tanks, or compressed air
 Oxygen flow meter and oxygen flush valve
 Anesthetic vaporizer: usually either Isoflurane or Sevoflurane
 Breathing circuit – rebreathing (patients >7kg) or non-
rebreathing (patients <7 kg)
 Pop-off valve: keep OPEN unless manually “sighing” for patient
 Pressure manometer: do not go above 20cm while “sighing”
 CO2 absorber/granules
 Reservoir bag: 1L (very small dogs/cats) – 5L (very large dogs)
 Scavenging system: either a charcoal F-air canister (passive) or
an outlet pipe into the ceiling or wall of the hospital (active).
Anesthesia Machine
Note: Not all machines will be set up exactly the same way!
Anesthetic Monitoring
 Most important piece of equipment is the monitoring
technician and a stethoscope.
 Vital Signs:
 HR, RR, MM/CRT, EKG, EtCO2, SPO2, BP, Temp. –
do NOT rely on your monitors; always visually and
manually check your patient.
 Many vital signs will be lower or slower than normal
due to anesthesia, but should not be dangerously so
for extended time.
 Check reflexes, eye position, and pupil size regularly:
refer to McCurnin’s pgs. 1102 – 1112 for tables and ranges.
Anesthesia Review
 Resources:
 Anesthesia and Analgesia textbook
 McCurnin’s Chapter 29: Veterinary Anesthesia

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Anesthesia review

  • 1. Anesthesia Review Anesthesia and Analgesia textbook McCurnin’s Chapter 29: Veterinary Anesthesia
  • 2. Anesthesia - Terms  Analgesia: pain relief.  General anesthesia: unconsciousness and insensibility to feeling and pain induced by administration of anesthetic agents (given alone or in combination).  Local anesthesia: loss of sensation in a localized body part or region induced by administration of a drug or other agent without the loss of consciousness.  Premedication: administration of an agent(s) before induction of general anesthesia to: calm/relax the patient, ease induction + recovery, minimize adverse effects, reduce amount of general anesthetic, muscle relaxation, pain control.
  • 3. Anesthesia – Terms  Sedation: state of calm or drowsiness.  Tranquilization: state of relaxation and reduced anxiety.  Neuroleptanalgesia: state of profound sedation and analgesia produced by simultaneous administration of an opioid and a tranquilizer.  Drug-based anesthetics: liquid agents injected into the patient (or applied to a specific area – “local”) to induce anesthesia (“general”).  Inhalant anesthetic: liquid agents vaporized in oxygen and administered via an anesthetic breathing system.
  • 4. Patient Preparation  Due to risk of nausea/vomiting caused by anesthetic agents, patients must be fasted prior to anesthetic procedures.  Dogs and cats: withhold food for 8 – 12 hours prior, water for 2 – 4 hours. Note: Neonates and patients <2kg should NOT be fasted due to risk for hypoglycemia.  Full patient history must be obtained.  Complete physical exam must be performed: note ANY and ALL abnormalities to the veterinarian.  Diagnostic testing (at least CBC/Chem) should be performed.  Do not preemptively write up the anesthetic protocol for a patient. Always consult with the veterinarian.
  • 5. Protocol  Anesthetic protocols will differ by veterinarian and procedure type. Consult before calculating a protocol for your patient.  Considerations:  Estimated length of procedure  Patient age: neonates, geriatric  Diagnostic testing results  Patient’s demeanor: fractious, stoic, anxious  Body condition score (BCS): obesity, cachexia  Breed and species: Sighthounds, brachycephalic  Overall patient health: high or extreme disease/risk factor such as GDV, head trauma, organ failure, sepsis, internal hemorrhage/rupture
  • 6. Common Pre-medications  Buprenorphine (Buprenex): partial agonist opioid; analgesic and sedative. Effective in cats.  Butorphanol (Torbugesic, Torbutrol): mixed agonist- antagonist opioid; analgesic, sedative, and cough suppressant. Effective in dogs when combined with Acepromazine.  Hydromorphone: agonist opioid; analgesia. Can cause vomiting, nausea, hypersalivation, shivering.  Naloxone: Reversal agent for opioids – have in stock! NOT given as a pre-med, but rather, to reverse adverse effects of opioids.  Acepromazine: sedation ONLY. Cannot be reversed – use with caution, especially in patients with seizure history. Used as a pre-med only when combined with analgesic medications
  • 7. Anesthetic Agents  Alpha-2 Agonists:  Often used for short, minimal procedures or in DKT combination for fractious feline patient induction.  Cause sedation, analgesia, and muscle relaxation.  Side effects: severe bradycardia, hypotension, cardiac arrhythmia, possible heart block.  Examples:  Dexmedetomidine (DexDomitor), reversed with Atipamezole (Antisedan).  Xylazine, reversed with Yohimbine.
  • 8. Anesthetic Agents  Propofol:  Ultra-short-acting IV anesthetic: quick induction, quick recovery.  High end dose: 6mg/kg. Do not give entire dose IV: give enough to intubate (“to effect”).  Can cause transient excitement and apnea.  Ketamine-Diazepam (“Ket-Val”):  IV anesthetic combination = 1:1 volume ratio.  Give entire dose IV slowly.  Quick induction; prolonged recovery.  Can cause hypersalivation and muscle tremors.
  • 9. Controlled Drugs  Some pre-meds and anesthetic agents are controlled substances, but NOT all anesthetic drugs are considered controlled drugs. Ex: alpha-2 agonists and Propofol do not needed to be logged.  The Controlled Substance Log in the hospital MUST include:  Date, owner’s and patient’s names, and address (or identification number), starting volume, ending volume, amount used, and initials/signature of the person who removed the drug from inventory.  The following veterinary drugs MUST be logged:  Hydromorphone, Morphine, Buprenorphine, Butorphanol, Ketamine, Fentanyl, Phenobarbital, Pentobarbital (Euthanasia solution), Diazepam (Valium), Telazol, Hydrocodone.
  • 10. Anesthetic Equipment  Endotracheal tubes: placed inside the trachea of an unconscious patient to administer oxygen and inhalant anesthetic to the patient.  Laryngoscopes: facilitate the placement of the endotracheal tube; also allow for full oral cavity and throat exam.  Masks: used to administer oxygen and inhalant anesthetic to patients that are NOT intubated.  Anesthetic (Induction) Chambers: solid, see-through boxes used to induce general anesthesia in fractious patients.  Anesthetic Machine: delivers oxygen and inhalant anesthetic agents to patient (general anesthesia).  LEAK TEST the machine every day prior to use!
  • 11. Intubation  Occurs after IV, IM or mask induction: have all supplies ready!  3 ET tubes (1 of the ideal size, 1 smaller, 1 larger), roll gauze to tie in tube, gauze sponge to grasp tongue, cuff inflation syringe (empty 6ml – 12ml), laryngoscope with appropriate sized blade, 0.1ml syringe of Lidocaine for feline laryngospasm (NO needle!).  Size choices:  Cats: 3.0 – 4.5mm  Most small dogs: 5.0 – 6.5mm,  Most medium dogs: 6.5 – 8.0mm,  Most large dogs: 8.0 – 11.0mm  Brachycephalic and obese patients: Always choose a smaller tube than you would feel is appropriate.
  • 12. Intubation  Intubate gently, do not overinflate the cuff, and verify the tube is not advanced too far past the thoracic inlet.  Connect patient to anesthetic machine and turn on gas.  Verify proper placement via auscultation of both sides of chest.  Inflate the cuff  Apply steady pressure to the reservoir bag while simultaneously filling the cuff slowly.  Stop inflating the cuff when you can no longer hear air escaping from the lungs around the tube.  Relieve pressure on the bag and make sure the pop-off valve is open.
  • 13. Intubation  Possible Complications:  Patient is waking up.  Patient has a low pulse oximetry (hypoxia).  Patient is not breathing properly.  Verify the ET tube is placed properly:  Measure the tube to verify it is not advanced too far down into one of the mainstem bronchi (auscultate for breath sounds).  Verify the tube is not too thin or too wide in diameter for the patient’s throat size.  Verify the cuff is appropriately inflated.  Verify there is no air leaking from the anesthesia machine tubing into your patient = “leak check”.
  • 14. Anesthetic Machines  Parts of the machine:  Oxygen supply: can either be E- or H-tanks, or compressed air  Oxygen flow meter and oxygen flush valve  Anesthetic vaporizer: usually either Isoflurane or Sevoflurane  Breathing circuit – rebreathing (patients >7kg) or non- rebreathing (patients <7 kg)  Pop-off valve: keep OPEN unless manually “sighing” for patient  Pressure manometer: do not go above 20cm while “sighing”  CO2 absorber/granules  Reservoir bag: 1L (very small dogs/cats) – 5L (very large dogs)  Scavenging system: either a charcoal F-air canister (passive) or an outlet pipe into the ceiling or wall of the hospital (active).
  • 15. Anesthesia Machine Note: Not all machines will be set up exactly the same way!
  • 16. Anesthetic Monitoring  Most important piece of equipment is the monitoring technician and a stethoscope.  Vital Signs:  HR, RR, MM/CRT, EKG, EtCO2, SPO2, BP, Temp. – do NOT rely on your monitors; always visually and manually check your patient.  Many vital signs will be lower or slower than normal due to anesthesia, but should not be dangerously so for extended time.  Check reflexes, eye position, and pupil size regularly: refer to McCurnin’s pgs. 1102 – 1112 for tables and ranges.
  • 17. Anesthesia Review  Resources:  Anesthesia and Analgesia textbook  McCurnin’s Chapter 29: Veterinary Anesthesia