2. ‹#›
About StemGenn Therapeutics
• Stemgenn Therapeutics is a leading Cell therapy &
Regenerative medicine services company that supports
the development and commercialization of cellular
therapies and stem cell research. Stemgenn provides
cGMP-compliant cell manufacturing and consulting
services that address regulatory, financial, technical,
process, training and quality system strategies. Services
include a full spectrum of support and consulting related
to process and product development, validation, due
diligence evaluations, tissue collection, processing, and
storage, product manufacturing, distribution and
transportation.
3. ‹#›
Why StemGenn Therapeutics?
• As Stem cell have inherent properties to self renew and
differentiation into other cell types. They are multi potent
and found within our body.
• No side effects: as it's found in patient's own tissues or
blood, chances of rejection and infection is negligible.
• World class clinicians and experts from Regenerative
Medicine.
• Cost Effectiveness: autologous stem cell transplant is very
much affordable.
• Non- Surgical Procedure & convenient.
• Proven Results.
4. ‹#›
The Management & Medical Advisory Board
• Mr. Prabhu Mishra : CEO, Co-Founder
• Ms. Richa Jha : MD, Co-Founder
• Ms. Shreyashi Gangopadhyay: Director- Business Development
• Dr. Sharda Jain : Chairman- Global StemGenn ( Medical Advisory board StemGenn)
• Dr. H S Bedi :Director- Cardio Vascular, CMC Ludhiana.( Med. Adv. Board, StemGenn)
• Dr. Satish Totey: Stem Cell Scientist over 35 years Experiences. ( MAB- StemGenn)
• Dr. Roopam Jain: MD Transfusion Medicine, Assoc. Professor. (MAB )
5. ‹#›
Life Style Disease:
• Globally , diabetes, obesity, liver cirrhosis and
cardiovascular diseases , ageing are affecting the health
and well-being of hundreds of millions of people. These
diseases are no longer confined to the developed world
as millions of people in developing countries are
adopting a westernized lifestyle and are being affected
by these diseases .
• 'Lifestyle' diseases the world's biggest killer.
6. ‹#›
Which Diseases Falls in Lifestyle diseases:
• Lifestyle diseases or diseases of longevity or diseases of civilization are
:diseases that appear to increase in frequency as countries become more
industrialized and people live longer.
• They can include Alzheimer's disease, Arthritis, atherosclerosis, asthma,
some kinds of cancer, chronic liver disease or cirrhosis, chronic
obstructive pulmonary disease, Type 2 diabetes, heart disease, metabolic
syndrome, chronic renal failure, osteoporosis, stroke, depression and
obesity.
• Some commenters maintain a distinction between diseases of longevity
and diseases of civilization. Certain diseases, such as diabetes, dental
caries or asthma appear at greater rates in young populations living in
the "western" way; their increased incidence is not related to age, so the
terms cannot accurately be used interchangeably for all diseases.]
7. ‹#›
Diabetes Type 1 & Type 2
The Diabetes affects more people and causes more
deaths each year than breast cancer and AIDS combined.
The American Diabetes Association estimates that 16
million people, 5.9% of the U.S. population are affected
with Diabetes.
Over sixty two million diabetic people presently
diagnosed with the disease in India (5% of the India
population).
It is predicted that by 2030 DM could afflict up to 79.4
million people in India, whereas China (42.3 million) and
also the USA (30.3 million).
8. ‹#›
What exactly is diabetes?
abnormally high levels of glucose in the blood
Potential complications include blindness, stroke, kidney failure, nerve disease, poor circulation, and amputation
• Type 1 Diabetes
juvenile-on set
typically affects children and young adults
immune system attacks and destroys beta cells in the islets of Langerhans of the pancreas that
normally produce insulin
glucose does not enter the cells and therefore accumulates in the blood
90-100% loss in beta cell mass
Type 2 Diabetes
adult-onset diabetes
typically affects older, sedentary, and overweight individuals with a family history of diabetes.
body cannot use insulin effectively
due to insulin resistance, glucose accumulates in the blood
30-50% loss in beta cell mass
9. ‹#›
Stem cell
Stem cell
( unlimited
cell division )
Specialized cell
(e.g., white blood cell)
Undifferentiated / unspecialized
cells
Undifferentiated cells can
differentiate to yield major
specialized cell
types or organs.
Self-renewal property is to
maintain and repair the tissue.
Thus they have potential to replace
cell tissue damaged by severe
illnesses.
Stem Cells and their
Characteristics:
10. ‹#›
Stem Cell Source: Embryonic and Adult . In Adult: Cord Blood,
Peripheral Blood, Bone Marrow, Fat, Brain , etc.
11. ‹#›
Procedure Of Stem cell Therapy
• 1. Counseling
• 2. selection of Patient
• 3. Required Test as: CBC, LFT, KFT, Serum Creatinine, USG
Abdomen, HbA1c, C-Peptide, Sugar Charting , Echo, TMT, PFT ,Viral
Markers and General Physician evaluation.
• 4. Collection Of Bone Marrow/ PBSC( By Apheresis) /
Lipoaspiration of Fat
• 5. Processing of cells.
• 6. Infusion Of Cells .
• 7. Post Follow up care & Instructions.
• 8. Nutrients, Supplements & Exercise.