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_________________________________
* Corresponding author:
N.Junior Sundresh,
Associate Professor of Surgery,
Raja Muthiah Medical College & Hospital,
Chidambaram. -
Tamilnadu.
E.Mail: juniorsundresh@yahoo.com
Available Online at: www.ijrpp.com
FIND OUT THE PREVALANCE OF VARIOUS
DISEASES PRODUCING
*1
N.Junior sundresh, 2
S.Narendran,
1
Associate Professor of Surgery
University, Chidambaram.
2
Emeritus Professor of Surgery,
University, Chidambaram.
3
Professor of Surgery Raja Muthiah Medical College &
Chidambaram.
_____ _______________________________
ABSTRACT
Non variceal upper G.I bleeding is the bleeding from a source proximal to the ligament of teres. Advances in
medical technology particulars the increased availability and application or diagnostic and the operatic endoscopy
have been instrumented in evaluated and successful treatment of patients with major bleeding. This study aims to
find out various non-variceal diseases producing upper G.I. bleeds and the various modalities of treatment.
Keywords: Non variceal upper G.I bleeding
_____________________________________________________
INTRODUCTION
Upper GI bleeding is defined as bleeding from a
source proximal to the ligament of teres. It is
common and potentially deadly condition
accounting for approximately 85% of hospital
admissions for G.I. bleeding upper GI bleeding
presents as hematemesis and it melena. Numerous
advances in medical technology, particularly the
improved availability and applications of diagnostic
and therapeutic endoscopy have been instrumental
in the evaluation and successful treatment of
patients with major bleeding.
_________________________________
Raja Muthiah Medical College & Hospital,
Available Online at: www.ijrpp.com Print ISSN : 2278 - 2648
Online ISSN: 2278 - 2656
(Research article)
FIND OUT THE PREVALANCE OF VARIOUS NON-VARICEAL
DISEASES PRODUCING UPPER GI BLEEDING
S.Narendran, 3
M.Ramanathan
Surgery, Raja Muthiah Medical College & Hospital, Annamalai
Professor of Surgery, Raja Muthiah Medical College & Hospital, Annamalai
Raja Muthiah Medical College & Hospital, Annamalai University
______________________________________________________________
Non variceal upper G.I bleeding is the bleeding from a source proximal to the ligament of teres. Advances in
technology particulars the increased availability and application or diagnostic and the operatic endoscopy
have been instrumented in evaluated and successful treatment of patients with major bleeding. This study aims to
es producing upper G.I. bleeds and the various modalities of treatment.
bleeding, hematemesis, Melena
__________________________________________________________________________________________
Upper GI bleeding is defined as bleeding from a
source proximal to the ligament of teres. It is
common and potentially deadly condition
approximately 85% of hospital
admissions for G.I. bleeding upper GI bleeding
elena. Numerous
advances in medical technology, particularly the
improved availability and applications of diagnostic
e been instrumental
in the evaluation and successful treatment of
The main aim of the study is,
 To find out the prevalence of various non
variceal diseases producing upper GI bleed.
 To study the various modalities of
treatment and also to study those cases
which will require emergency surgery with
special attention to endoscopy.
 To plan the mode of management with
respect to non-variceal upper GI bleeding in
the future.
International Journal of
Research in Pharmacology and
Pharmacotherapeutics
46
(Research article)
VARICEAL
Muthiah Medical College & Hospital, Annamalai
Raja Muthiah Medical College & Hospital, Annamalai
Hospital, Annamalai University,
_______________________________
Non variceal upper G.I bleeding is the bleeding from a source proximal to the ligament of teres. Advances in
technology particulars the increased availability and application or diagnostic and the operatic endoscopy
have been instrumented in evaluated and successful treatment of patients with major bleeding. This study aims to
es producing upper G.I. bleeds and the various modalities of treatment.
________________________
To find out the prevalence of various non-
variceal diseases producing upper GI bleed.
To study the various modalities of
treatment and also to study those cases
which will require emergency surgery with
special attention to endoscopy.
To plan the mode of management with
variceal upper GI bleeding in
Journal of
Research in Pharmacology and
Pharmacotherapeutics
47
N.Sundresh et et al / Int. Jour. of Res. in Pharmacology and Pharmacotherapeutics Vol-1[1] 2012 [46-51]
www.ijrpp.com
.Materials and Methods
Forty seven cases of upper bleeding were admitted
during the period of 3 years of study in RMMCH,
Chidambaram. As soon as the patient is admitted a
detailed history is taken from the close relatives of
the patient to understand the nature and amount of
blood loss during the history taking itself. All
relevant investigations were done.
Results
Out of the 47 patients, majority of cases (around 16)
were from the age group 41-50 years. Minimum age
incidence was found in the age group 11-20 years
out of the 47 patients 36 were male and 11 were
female, the male: female ratio being 3:1 the most
common mode of presentation was haematemesis,
and least was melena. Erosive gastritis was the most
common etiological factor. Most of the cases were
managed conservatively.
Discussion
The total of 47 patients studied, majority was in the
age group of 41-50 years with male prominence.
Haematemesis is the predominant presenting
symptom with the introduction of upper GI
endoscopy. Source of bleeding can be detected in
more than 90% of cases. The introduction of proton
pump inhibitors and availability of easily endoscopic
management has brought down the complication
and need for survey in peptic ulcer disease. Through
the necessity of emergency surgery has considerably
reduced it is still preferred to be the important life-
saving produce for those patients who do not
respond to conjunctive line of management.
Table: 1
Age Incidence
Age in Years No. of cases Percentage
11 – 20 1 21.2 %
21 – 30 6 12.76 %
31 – 40 10 21.27 %
41 – 50 16 34.04 %
51 – 60 8 17.02 %
61 – 70 4 8.51 %
71 – 80 2 4.25 %
48
N.Sundresh et et al / Int. Jour. of Res. in Pharmacology and Pharmacotherapeutics Vol-1[1] 2012 [46-51]
www.ijrpp.com
Table: 2
Sex Incidence
Sex No. of cases Percentage
Male 36 76.59 %
Female 11 23.4 %
Table: 3
Presenting Symptom
Symptom No. of Cases Percentage
Haematemesis 32 68.08 %
Melena 3 6.38 %
Haematemesis and melena 12 25.53 %
Table: 4
Presenting Symptom
Lesions Identified No. of Cases Percentage
Erosive gastritis 29 61.70 %
Duodenal ulcer 10 21.27 %
Gastric ulcer 2 4.25%
Mallory – Weiss tear 2 4.25%
Carcinoma stomach 2 4.25%
Dieulafoy’s lesion 1 2.12%
Necrotizing pancreatitis 1 2.12%
49
N.Sundresh et et al / Int. Jour. of Res. in Pharmacology and Pharmacotherapeutics Vol-1[1] 2012 [46-51]
www.ijrpp.com
Table: 5
Diagnosis and Outcome
Diagnosis No. of Cases Conservative Surgery Mortality
Erosive gastritis 29 100 % - -
Duodenal ulcer 10 80 % 20 % 10 %
Gastric ulcer 2 100 % - -
CA stomach 2 100 % - -
Mallory – Weiss tear 2 100 % - -
Dieulafoy’s lesion 1 100 % - -
Necrotising Pancreatitis 1 100 % - -
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Non variceal upper gi bleeding ijrpp

  • 1. _________________________________ * Corresponding author: N.Junior Sundresh, Associate Professor of Surgery, Raja Muthiah Medical College & Hospital, Chidambaram. - Tamilnadu. E.Mail: juniorsundresh@yahoo.com Available Online at: www.ijrpp.com FIND OUT THE PREVALANCE OF VARIOUS DISEASES PRODUCING *1 N.Junior sundresh, 2 S.Narendran, 1 Associate Professor of Surgery University, Chidambaram. 2 Emeritus Professor of Surgery, University, Chidambaram. 3 Professor of Surgery Raja Muthiah Medical College & Chidambaram. _____ _______________________________ ABSTRACT Non variceal upper G.I bleeding is the bleeding from a source proximal to the ligament of teres. Advances in medical technology particulars the increased availability and application or diagnostic and the operatic endoscopy have been instrumented in evaluated and successful treatment of patients with major bleeding. This study aims to find out various non-variceal diseases producing upper G.I. bleeds and the various modalities of treatment. Keywords: Non variceal upper G.I bleeding _____________________________________________________ INTRODUCTION Upper GI bleeding is defined as bleeding from a source proximal to the ligament of teres. It is common and potentially deadly condition accounting for approximately 85% of hospital admissions for G.I. bleeding upper GI bleeding presents as hematemesis and it melena. Numerous advances in medical technology, particularly the improved availability and applications of diagnostic and therapeutic endoscopy have been instrumental in the evaluation and successful treatment of patients with major bleeding. _________________________________ Raja Muthiah Medical College & Hospital, Available Online at: www.ijrpp.com Print ISSN : 2278 - 2648 Online ISSN: 2278 - 2656 (Research article) FIND OUT THE PREVALANCE OF VARIOUS NON-VARICEAL DISEASES PRODUCING UPPER GI BLEEDING S.Narendran, 3 M.Ramanathan Surgery, Raja Muthiah Medical College & Hospital, Annamalai Professor of Surgery, Raja Muthiah Medical College & Hospital, Annamalai Raja Muthiah Medical College & Hospital, Annamalai University ______________________________________________________________ Non variceal upper G.I bleeding is the bleeding from a source proximal to the ligament of teres. Advances in technology particulars the increased availability and application or diagnostic and the operatic endoscopy have been instrumented in evaluated and successful treatment of patients with major bleeding. This study aims to es producing upper G.I. bleeds and the various modalities of treatment. bleeding, hematemesis, Melena __________________________________________________________________________________________ Upper GI bleeding is defined as bleeding from a source proximal to the ligament of teres. It is common and potentially deadly condition approximately 85% of hospital admissions for G.I. bleeding upper GI bleeding elena. Numerous advances in medical technology, particularly the improved availability and applications of diagnostic e been instrumental in the evaluation and successful treatment of The main aim of the study is,  To find out the prevalence of various non variceal diseases producing upper GI bleed.  To study the various modalities of treatment and also to study those cases which will require emergency surgery with special attention to endoscopy.  To plan the mode of management with respect to non-variceal upper GI bleeding in the future. International Journal of Research in Pharmacology and Pharmacotherapeutics 46 (Research article) VARICEAL Muthiah Medical College & Hospital, Annamalai Raja Muthiah Medical College & Hospital, Annamalai Hospital, Annamalai University, _______________________________ Non variceal upper G.I bleeding is the bleeding from a source proximal to the ligament of teres. Advances in technology particulars the increased availability and application or diagnostic and the operatic endoscopy have been instrumented in evaluated and successful treatment of patients with major bleeding. This study aims to es producing upper G.I. bleeds and the various modalities of treatment. ________________________ To find out the prevalence of various non- variceal diseases producing upper GI bleed. To study the various modalities of treatment and also to study those cases which will require emergency surgery with special attention to endoscopy. To plan the mode of management with variceal upper GI bleeding in Journal of Research in Pharmacology and Pharmacotherapeutics
  • 2. 47 N.Sundresh et et al / Int. Jour. of Res. in Pharmacology and Pharmacotherapeutics Vol-1[1] 2012 [46-51] www.ijrpp.com .Materials and Methods Forty seven cases of upper bleeding were admitted during the period of 3 years of study in RMMCH, Chidambaram. As soon as the patient is admitted a detailed history is taken from the close relatives of the patient to understand the nature and amount of blood loss during the history taking itself. All relevant investigations were done. Results Out of the 47 patients, majority of cases (around 16) were from the age group 41-50 years. Minimum age incidence was found in the age group 11-20 years out of the 47 patients 36 were male and 11 were female, the male: female ratio being 3:1 the most common mode of presentation was haematemesis, and least was melena. Erosive gastritis was the most common etiological factor. Most of the cases were managed conservatively. Discussion The total of 47 patients studied, majority was in the age group of 41-50 years with male prominence. Haematemesis is the predominant presenting symptom with the introduction of upper GI endoscopy. Source of bleeding can be detected in more than 90% of cases. The introduction of proton pump inhibitors and availability of easily endoscopic management has brought down the complication and need for survey in peptic ulcer disease. Through the necessity of emergency surgery has considerably reduced it is still preferred to be the important life- saving produce for those patients who do not respond to conjunctive line of management. Table: 1 Age Incidence Age in Years No. of cases Percentage 11 – 20 1 21.2 % 21 – 30 6 12.76 % 31 – 40 10 21.27 % 41 – 50 16 34.04 % 51 – 60 8 17.02 % 61 – 70 4 8.51 % 71 – 80 2 4.25 %
  • 3. 48 N.Sundresh et et al / Int. Jour. of Res. in Pharmacology and Pharmacotherapeutics Vol-1[1] 2012 [46-51] www.ijrpp.com Table: 2 Sex Incidence Sex No. of cases Percentage Male 36 76.59 % Female 11 23.4 % Table: 3 Presenting Symptom Symptom No. of Cases Percentage Haematemesis 32 68.08 % Melena 3 6.38 % Haematemesis and melena 12 25.53 % Table: 4 Presenting Symptom Lesions Identified No. of Cases Percentage Erosive gastritis 29 61.70 % Duodenal ulcer 10 21.27 % Gastric ulcer 2 4.25% Mallory – Weiss tear 2 4.25% Carcinoma stomach 2 4.25% Dieulafoy’s lesion 1 2.12% Necrotizing pancreatitis 1 2.12%
  • 4. 49 N.Sundresh et et al / Int. Jour. of Res. in Pharmacology and Pharmacotherapeutics Vol-1[1] 2012 [46-51] www.ijrpp.com Table: 5 Diagnosis and Outcome Diagnosis No. of Cases Conservative Surgery Mortality Erosive gastritis 29 100 % - - Duodenal ulcer 10 80 % 20 % 10 % Gastric ulcer 2 100 % - - CA stomach 2 100 % - - Mallory – Weiss tear 2 100 % - - Dieulafoy’s lesion 1 100 % - - Necrotising Pancreatitis 1 100 % - - REFERENCE 1. Gilbert, D.A. et al. "The National ASGE survey on upper Gl bleeding. III. Endoscopy in upper grastrointestinal bleeding" Gastrointest. Endosc. 27: 94-102. 2. Silverstein, F.G. et al. "The National ASGE Survey on UGI bleeding. I. Study design and baseline data". Gastrointest. Endosc. 1981.27:73-9. . 3. Eastwood, G.I. "Does the patient with upper GI bleeding benefit from endoscopy?" Dig. Dis. Sic. 1981. 26: 225. 4. Savary, P.J., Miller et a. "Hand book and Atlas of Endoscopy" 1978. 5. Atkinson, ML, Bottrill, M.B. and Edwards A.T., "Mucosal tears at the esophagus gastric junction: Gut 1961; 2: 1-11. 6. Jordan, S.M and Kiefer E.D. "Complications of peptic ulcer; their prognostic significance." JAMA 1934; 103: 2004-7. 7. Mathewson K., Pugh, S., Northfield T.C. "Which peptic ulcer patients bleed?" Gut 1988; 29: 70-4. 8. Swain Paul, C. "Pathophysiology of bleeding lesions" Gastroinest. Endosc. 1990; 36: 521- 23. 9. Hunt, P.S., Hansky, J., Korman, MG. "Mortality in patients with haematemesis and melena; a prospective study" Br. Med. J. 1979; 1: 1238-1240. 10. Karvoner, Al et al. "Gastric mucosal erosions: AN endoscopic, histological and functional study". Scand. J. Gastroenterol, 1983; 18: 1051. 11. Somerville K et al. "Non-steroidal anti- inflammtory drugs and bleeding peptic ulcer" Lancet 1986 ; 1: 462. 12. Lud et al. "Gastric aspiration in localization of gastrointestinal haemorhage" JAMA 1979; 241: 576-578. 13. Cottonm P.B. et a; "early endoscopy of oesophagus, stomach and duodenum in patients with haematemesis ad melaena." Arch. Surg. 1973; 197: 13-7. 14. Thomas G.E. et al. "Survey of management of acute upper GI haemorrhage." J.R. Soc. Med. 1978; 73: 90-5. 15. Foster et al. "Stigmata of recent haemorrhage in diagnosis and prognosis of upper GI he Br. Med. J. 1978, 1: 1173-1177. 16. Laurence, BH et al "Endoscopic laser photocoagulation for bleeding peptic ulcers". Lancet 1980; 1: 124-5. 17. Alam, P. et al "Randomised study of massive bleeding from peptic ulceration". Ann. Surg 1965; 162: 561-577.
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