15. Melorheostosis It is usually apparent in early childhood and even in the first few days of life. About 50% of persons affected will develop the symptoms by the time they are 20 years of age. On x-rays, the disease's sclerotic bone lesions looks like wax dripping down the side of a candle. Hence its name; which is derived from the greek melos "limb" and rhein "to flow".