Framework Use in Clinical Research

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Health & Medicine

RE-AIM
Reach
Efficacy
Advocate
Implement
Maintenance
Framework Use in Clinical Research

Theory vs. Model vs. Framework: Nilsen
• Theory: principles, statements to explain things of the world;
explanatory and descriptive
• Model: a narrowed theory; descriptive
• Framework: structure, overview, outline of descriptive
categories

Pre-RE-AIM
• Impact of interventions
• I = R * E
• Missing aspects public health impact
• Did not take setting into consideration

RE-AIM
• Reach: Individual level measurement; participation out of
population
• Efficacy: Biological, behavioral outcomes, and QOL to measure
success
• Adoption: representation in the settings
• Implementation: individual (adherence) and setting (protocol
deviations)
• Maintenance: post study sustainability

RE-AIM1999 •- Public Health
- Evaluation
- All 5 are equally
important but may be
weighted differently
- Internal/External
validity
- Individual
interventions
Overtime
- Used in planning,
progress, report results
- Used outside of public
health
- Confusion over term
use
- Not all dimensions
used

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Framework Use in Clinical Research

1. RE-AIM Reach Efficacy Advocate Implement Maintenance Framework Use in Clinical Research

2. Theory vs. Model vs. Framework: Nilsen • Theory: principles, statements to explain things of the world; explanatory and descriptive • Model: a narrowed theory; descriptive • Framework: structure, overview, outline of descriptive categories

3. Pre-RE-AIM • Impact of interventions • I = R * E • Missing aspects public health impact • Did not take setting into consideration

4. Nilsen, P 2015

5. RE-AIM • Reach: Individual level measurement; participation out of population • Efficacy: Biological, behavioral outcomes, and QOL to measure success • Adoption: representation in the settings • Implementation: individual (adherence) and setting (protocol deviations) • Maintenance: post study sustainability

6. RE-AIM1999 •- Public Health - Evaluation - All 5 are equally important but may be weighted differently - Internal/External validity - Individual interventions Overtime - Used in planning, progress, report results - Used outside of public health - Confusion over term use - Not all dimensions used

Editor's Notes

Confuse reach and adoption

Framework Use in Clinical Research

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Editor's Notes