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HIV, AIDS, & Your
 Immune System
    By Daniel Marx
The Immune System
            To be “immune” means
             to be protected.
            Your immune system is
             made up of cells, tissues,
             and organs that work
             together to protect your
             body
            Your body consists of
             white and red blood cells
            White blood cells form
             the immune system
2 Kinds of White Blood Cells
 1) Phagocytes – Chew up
  invading germs
 2) Lymphocytes (B cell) –
  Remember and recognize
  previous invaders (i.e. chicken
  pox)
 It is a type of lymphocyte, or
  “helper T cell” that is involved
  in fighting off HIV
 Antigen - Thing that, when
  introduced into the body,
  triggers the production of an
  antibody by the immune
  system, which will kill the
  antigen that is recognized as a
  foreign invader.
Process of Immune System
What Is HIV?
 “HIV” stands for human immunodeficiency
  virus
 It is a virus that attacks your immune
  system by latching onto Helper T cells
 Uses T cells to reproduce, or “replicate”
 Eventually overwhelms the body and
  becomes AIDS
 Or “autoimmune deficiency syndrome”
HIV Skit!
   I will need 7 volunteers      Instructions:
   Each will take a role:        The Person will just
   • 1 Narrator                   stand there. The
                                   Immune Defenses will
   • 1 Person
                                   stand in front of the
   • 2 Immune Defenses            person, blocking the
   • 1 Disease                    Disease until HIV
   • 1 HIV virus                  pushes them aside. The
   • 1 ARV pill                   ARV can come in and
                                   help the immune system
                                   push HIV back.
How Can You Get HIV??
HIV Incidence and Prevalence, US,
                1977-2006




   (Hall, Song, Rhodes, et al. 2008)
Prevalence Rates




   (Hall, Song, Rhodes, et al. 2008)
Initial Signs of HIV
How Can We Prevent HIV?
   Get Tested!
   Safe Sex (OR) Abstinence
   Avoid sharing needles
   Don’t Share razors or toothbrushes


(Department of Health and Human Services)
http://www.cdc.gov/hiv/resources/brochures/living
withhiv.htm#q8
References
   Center for Disease Control and Prevention (2011). HIV/AIDS. Retrieved from http://
    www.cdc.gov/hiv/.

   Hall HI, Song R, Rhodes P, et al. (2008). Estimation of HIV Incidence in the US. JAMA, 300
    520-529.

   Kim, S., Lagos, C., Lukomnik, J., Molacek, E., Murguia K. (2007). HIV/AIDS Educational Activities
    Lesson Plans. Beyond Traditional Borders Student Project. Retrieved from http://
    www.btb.rice.edu/design.cfm?doc_id=12214.

   The Nemours Foundation. (1995-2011). KidsHealth: HIV & AIDS. Retrieved from
    http://kidshealth.org/kid/health_problems/infection/hiv.html.

    Pantaleo G, Demarest JF, Schacker T, Vaccarezza M, Cohen OJ, Daucher M, Graziosi C, Schnittman
    SS, Quinn TC, Shaw GM, Perrin L, Tambussi G, Lazzarin A, Sekaly RP, Soudeyns H, Corey L, Fauci
    AS. (1997). "The qualitative nature of the primary immune response to HIV infection is a
    prognosticator of disease progression independent of the initial level of plasma viremia". Proc Natl
    Acad Sci U S A. 94 (1): 254–258. doi:10.1073/pnas.94.1.254. PMC 19306. PMID 8990195.

    Kahn, J. O. and Walker, B. D. (1998). "Acute Human Immunodeficiency Virus type 1 infection". N.
    Engl. J. Med. 331 (1): 33–39. doi:10.1056/NEJM199807023390107. PMID 9647878.

   Daar ES, Little S, Pitt J, et al. (2001). "Diagnosis of primary HIV-1 infection. Los Angeles County
    Primary HIV Infection Recruitment Network". Ann. Intern. Med. 134 (1): 25–9. PMID 11187417.

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Hiv, Aids, & Your Immune System, Sped 554

  • 1. HIV, AIDS, & Your Immune System By Daniel Marx
  • 2. The Immune System  To be “immune” means to be protected.  Your immune system is made up of cells, tissues, and organs that work together to protect your body  Your body consists of white and red blood cells  White blood cells form the immune system
  • 3. 2 Kinds of White Blood Cells  1) Phagocytes – Chew up invading germs  2) Lymphocytes (B cell) – Remember and recognize previous invaders (i.e. chicken pox)  It is a type of lymphocyte, or “helper T cell” that is involved in fighting off HIV  Antigen - Thing that, when introduced into the body, triggers the production of an antibody by the immune system, which will kill the antigen that is recognized as a foreign invader.
  • 5. What Is HIV?  “HIV” stands for human immunodeficiency virus  It is a virus that attacks your immune system by latching onto Helper T cells  Uses T cells to reproduce, or “replicate”  Eventually overwhelms the body and becomes AIDS  Or “autoimmune deficiency syndrome”
  • 6. HIV Skit!  I will need 7 volunteers  Instructions:  Each will take a role:  The Person will just  • 1 Narrator stand there. The Immune Defenses will  • 1 Person stand in front of the  • 2 Immune Defenses person, blocking the  • 1 Disease Disease until HIV  • 1 HIV virus pushes them aside. The  • 1 ARV pill ARV can come in and help the immune system push HIV back.
  • 7. How Can You Get HIV??
  • 8. HIV Incidence and Prevalence, US, 1977-2006  (Hall, Song, Rhodes, et al. 2008)
  • 9. Prevalence Rates  (Hall, Song, Rhodes, et al. 2008)
  • 11. How Can We Prevent HIV?  Get Tested!  Safe Sex (OR) Abstinence  Avoid sharing needles  Don’t Share razors or toothbrushes (Department of Health and Human Services) http://www.cdc.gov/hiv/resources/brochures/living withhiv.htm#q8
  • 12. References  Center for Disease Control and Prevention (2011). HIV/AIDS. Retrieved from http:// www.cdc.gov/hiv/.  Hall HI, Song R, Rhodes P, et al. (2008). Estimation of HIV Incidence in the US. JAMA, 300 520-529.  Kim, S., Lagos, C., Lukomnik, J., Molacek, E., Murguia K. (2007). HIV/AIDS Educational Activities Lesson Plans. Beyond Traditional Borders Student Project. Retrieved from http:// www.btb.rice.edu/design.cfm?doc_id=12214.  The Nemours Foundation. (1995-2011). KidsHealth: HIV & AIDS. Retrieved from http://kidshealth.org/kid/health_problems/infection/hiv.html.  Pantaleo G, Demarest JF, Schacker T, Vaccarezza M, Cohen OJ, Daucher M, Graziosi C, Schnittman SS, Quinn TC, Shaw GM, Perrin L, Tambussi G, Lazzarin A, Sekaly RP, Soudeyns H, Corey L, Fauci AS. (1997). "The qualitative nature of the primary immune response to HIV infection is a prognosticator of disease progression independent of the initial level of plasma viremia". Proc Natl Acad Sci U S A. 94 (1): 254–258. doi:10.1073/pnas.94.1.254. PMC 19306. PMID 8990195.  Kahn, J. O. and Walker, B. D. (1998). "Acute Human Immunodeficiency Virus type 1 infection". N. Engl. J. Med. 331 (1): 33–39. doi:10.1056/NEJM199807023390107. PMID 9647878.  Daar ES, Little S, Pitt J, et al. (2001). "Diagnosis of primary HIV-1 infection. Los Angeles County Primary HIV Infection Recruitment Network". Ann. Intern. Med. 134 (1): 25–9. PMID 11187417.