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What exactly are Chromosomes,
DNA and Genes?
Introduction to Genetics
Introduction to Genetics Video
Chromosome
• 46 inside every cell
• Chromosomes are in
the cell in pairs.   Dad’s Chromosome Mom’s Chromosome

• One came from mom and one came from dad.
DNA - deoxyribonucleic (say: dee-ox-
see-ri-bo-nyoo-clay-ik) acid
• Long strands of genetic code
• Makes up chromosomes in plants and animals

                                      DNA
Genes
• Tiny pieces of DNA that are instructions for
  specific traits
Traits
• Things that you inherit from your parents
• Examples: Hair color, eye color and having
  freckles or not
• Through sexual reproduction you inherited a set
  of traits
Traits
• Pairs of letters are used to define genes in your
  body
• CAPTIAL LETTERS are used to represent
  DOMINANT genes
• lower case letters are used to represent recessive
  genes
• Dominant trait: If you receive even one of these
  in the pair, you will get a specific trait.
• Recessive trait: You have to have two of these in
  the pair to get a specific trait
Genotypes
• The letter associated with the gene
 ▫ Example: W (dominant widow’s peak) w (recessive no
   widow’s peak)
Phenotypes
• This is the "outward, physical manifestation“
• The actual physical trait
 ▫ Example: You have a widow’s peak.
Allele
• Allele: The single letter such as the a or the A.
Heterozygous – having two different
alleles
  • AA
  • bb
Homozygous – having the same alleles

 • Aa
 • Bb
Purebred or Hybrid?
• Purebred: AA or aa
• Hybrid: Aa
Practice:
B – brown hair                b – red hair

My genes: Bb

        What color hair will I have?

 Is Bb the phenotype or the genotype?

      Are my genes heterozygous or
              homozygous?
Practice:
A – attached earlobe    a – unattached earlobe

My genes: aa

               What will my earlobes do?

  Is attached earlobe the phenotype or the
                  genotype?

          Is my genotype homozygous or
                   heterozygous?
Practice:
D – dimples        d – no dimples

My genes: DD


               Do I have dimples or not?

                What is the genotype?

         Is my genotype heterozygous or
                  homozygous?
Quiz
F – freckles      f – no freckles

My genes: FF


               Do I have freckles or not?

               What is the phenotype?

                What is the genotype?

   Is my genotype heterozygous or homozygous?

      Which parent carried the dominant gene?
Mom              Dad has
has               brown eyes
blue              (BB or Bb)
eyes              Therefore, Dad must
(bb)              have the Bb genotype,
                  because he must have
                  given her the “b” allele.
       Daughter   His “b” allele is masked
                  by his “B”/dominant

         has      allele.
What is a PUNNETT SQUARE?
• A tool to predict the probability of certain
  traits in offspring that shows the different
  ways alleles can combine
• A way to show
 phenotype & genotype
• A chart that shows
all the possible
combinations of alleles
that can result when
genes are crossed
Punnett Squares Video
Using a PUNNETT SQUARE
 To set up a Punnett square, draw a large
  square, and then divide it into 4 equal
  sections (also squares). It should look
  something like this:
Using a PUNNETT SQUARE
• Now you need two parents to mate, ones with
  a known genotype

• For example, Brown hair (genotype BB) and
  blonde hair (genotype Bb). BB x Bb

• In this scenario, the Mom has brown hair.
  The dad blonde hair.
Using a PUNNETT SQUARE
 Place one of the parents on top, and one on the
   left. You should get a something similar to
   this:

               B            b
     B

     B
Using a PUNNETT SQUARE
• The two-letter combinations are the possible
  genotypes of offspring

• They are: BB, Bb, BB, and Bb genotypes

• From this it is possible to determine the
  probability (chance) that a baby will have a
  brown phenotype (2/4 or 50%) or a blonde
  phenotype (2/4 or 50%)
Does it work with animals and plants?
• Yes, all of this works the same way in
  determining the outcome of combining animals
  and plants.
•How can we relate this to
 selective breeding?
•How can we relate this to
 genetic engineering?

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Genetics introduction

  • 1. What exactly are Chromosomes, DNA and Genes? Introduction to Genetics
  • 3. Chromosome • 46 inside every cell • Chromosomes are in the cell in pairs. Dad’s Chromosome Mom’s Chromosome • One came from mom and one came from dad.
  • 4. DNA - deoxyribonucleic (say: dee-ox- see-ri-bo-nyoo-clay-ik) acid • Long strands of genetic code • Makes up chromosomes in plants and animals DNA
  • 5. Genes • Tiny pieces of DNA that are instructions for specific traits
  • 6. Traits • Things that you inherit from your parents • Examples: Hair color, eye color and having freckles or not • Through sexual reproduction you inherited a set of traits
  • 7. Traits • Pairs of letters are used to define genes in your body • CAPTIAL LETTERS are used to represent DOMINANT genes • lower case letters are used to represent recessive genes • Dominant trait: If you receive even one of these in the pair, you will get a specific trait. • Recessive trait: You have to have two of these in the pair to get a specific trait
  • 8.
  • 9. Genotypes • The letter associated with the gene ▫ Example: W (dominant widow’s peak) w (recessive no widow’s peak)
  • 10. Phenotypes • This is the "outward, physical manifestation“ • The actual physical trait ▫ Example: You have a widow’s peak.
  • 11. Allele • Allele: The single letter such as the a or the A.
  • 12. Heterozygous – having two different alleles • AA • bb
  • 13. Homozygous – having the same alleles • Aa • Bb
  • 14. Purebred or Hybrid? • Purebred: AA or aa • Hybrid: Aa
  • 15. Practice: B – brown hair b – red hair My genes: Bb What color hair will I have? Is Bb the phenotype or the genotype? Are my genes heterozygous or homozygous?
  • 16. Practice: A – attached earlobe a – unattached earlobe My genes: aa What will my earlobes do? Is attached earlobe the phenotype or the genotype? Is my genotype homozygous or heterozygous?
  • 17. Practice: D – dimples d – no dimples My genes: DD Do I have dimples or not? What is the genotype? Is my genotype heterozygous or homozygous?
  • 18. Quiz F – freckles f – no freckles My genes: FF Do I have freckles or not? What is the phenotype? What is the genotype? Is my genotype heterozygous or homozygous? Which parent carried the dominant gene?
  • 19. Mom Dad has has brown eyes blue (BB or Bb) eyes Therefore, Dad must (bb) have the Bb genotype, because he must have given her the “b” allele. Daughter His “b” allele is masked by his “B”/dominant has allele.
  • 20. What is a PUNNETT SQUARE? • A tool to predict the probability of certain traits in offspring that shows the different ways alleles can combine • A way to show phenotype & genotype • A chart that shows all the possible combinations of alleles that can result when genes are crossed
  • 22. Using a PUNNETT SQUARE To set up a Punnett square, draw a large square, and then divide it into 4 equal sections (also squares). It should look something like this:
  • 23. Using a PUNNETT SQUARE • Now you need two parents to mate, ones with a known genotype • For example, Brown hair (genotype BB) and blonde hair (genotype Bb). BB x Bb • In this scenario, the Mom has brown hair. The dad blonde hair.
  • 24. Using a PUNNETT SQUARE Place one of the parents on top, and one on the left. You should get a something similar to this: B b B B
  • 25. Using a PUNNETT SQUARE • The two-letter combinations are the possible genotypes of offspring • They are: BB, Bb, BB, and Bb genotypes • From this it is possible to determine the probability (chance) that a baby will have a brown phenotype (2/4 or 50%) or a blonde phenotype (2/4 or 50%)
  • 26. Does it work with animals and plants? • Yes, all of this works the same way in determining the outcome of combining animals and plants. •How can we relate this to selective breeding? •How can we relate this to genetic engineering?