Phenotypic Expression Varies• Complete Dominance• Codominance• Incomplete Dominance• Sex-Linked    X-linked: gene lies on...
Phenotypic Expression Varies• Complete Dominance• Codominance• Incomplete Dominance• Sex-Linked    X-linked: gene lies on...
Phenotypic Expression Varies• Complete Dominance• Codominance• Incomplete Dominance• Sex-Linked    X-inactivation disable...
Practice• Sex-linked practice “Pipe Cleaner  babies and genetic traits”. Complete  and glue to page ___ of your notebook• ...
X Linked Genetics in the Calico Cat Calico is a coat color found in cats, which is caused by a SEX-LINKED, CODOMINANT alle...
Phenotypic Expression Varies• Complete Dominance• Codominance• Incomplete Dominance• Sex-Linked• Polygenic Traits    Cont...
Pedigree Rules• What is a pedigree?• *A pedigree is a chart that shows all  family members and how they are  related. It f...
– Boys                     Shaded-  Phenotype                           being  “traced”– Girls                X   deceased...
• Draw a pedigree for your immediate  family (mom, dad, step parents,  siblings, etc)
Trait
Trait
Trait        traits
Trait        traits
Trait
Trait
Pedigrees• Graphically shows the  lineage of a disorder in  a particular family• Be able to tell if  disorder is  dominant...
Pedigrees• Autosomal: Not sex-linked                              Where would a gene                              be if it...
Pedigrees• Autosomal: Not sex-linked                              Autosomal Dominant                                   How...
Pedigrees    Autosomal Recessive         How can we tell?
Pedigrees               Sex-Linked                How can we tell?     Is the X-linked dominant or recessive?
Pedigree Analysis Case Study•   Read family information•   Put family name at the top of your whiteboard•   Make a pedigre...
Genetics model 2012 fieldspart 4
Genetics model 2012 fieldspart 4
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Genetics model 2012 fieldspart 4

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Genetics model 2012 fieldspart 4

  1. 1. Phenotypic Expression Varies• Complete Dominance• Codominance• Incomplete Dominance• Sex-Linked  X-linked: gene lies on X chromosome (males only have one copy of the gene)  Y-linked: gene lies on Y chromosome (only males have the gene)  Contributes to younger Hemophilia mortality rate in males• Polygenic Traits
  2. 2. Phenotypic Expression Varies• Complete Dominance• Codominance• Incomplete Dominance• Sex-Linked  X-linked: gene lies on X chromosome (males only have one copy of the gene)  Y-linked: gene lies on Y chromosome (only males have the gene)  Contributes to younger mortality rate in males• Polygenic Traits Hemophilia
  3. 3. Phenotypic Expression Varies• Complete Dominance• Codominance• Incomplete Dominance• Sex-Linked  X-inactivation disables one x- chromosome in each cell (females and males each only use one x-chromosome)  can lead to unique phenotypes in females• Polygenic Traits
  4. 4. Practice• Sex-linked practice “Pipe Cleaner babies and genetic traits”. Complete and glue to page ___ of your notebook• OR, do sex linked handout
  5. 5. X Linked Genetics in the Calico Cat Calico is a coat color found in cats, which is caused by a SEX-LINKED, CODOMINANT allele. B = black, R = orange, and BR = calico. The following genotypes are possible; Female cats can be black XBXB, orange XRXR, or calico XBXR Male cats can be black XBY or orange XRY
  6. 6. Phenotypic Expression Varies• Complete Dominance• Codominance• Incomplete Dominance• Sex-Linked• Polygenic Traits  Controlled by more than one gene  Most common type of expression
  7. 7. Pedigree Rules• What is a pedigree?• *A pedigree is a chart that shows all family members and how they are related. It follows certain rules and shows genotypes and phenotypes.
  8. 8. – Boys Shaded- Phenotype being “traced”– Girls X deceased Marriage same level=same generation Mating w/o marriage Carrier (heterozygous) Kids Adopted
  9. 9. • Draw a pedigree for your immediate family (mom, dad, step parents, siblings, etc)
  10. 10. Trait
  11. 11. Trait
  12. 12. Trait traits
  13. 13. Trait traits
  14. 14. Trait
  15. 15. Trait
  16. 16. Pedigrees• Graphically shows the lineage of a disorder in a particular family• Be able to tell if disorder is dominant, recessive, or sex-linked from a pedigree• Be able to predict the chance that an indicated couple will have a child with the disorder
  17. 17. Pedigrees• Autosomal: Not sex-linked Where would a gene be if it was Human Chromosomes autosomal? Where would it be if it was sex-linked? What gender is this person?
  18. 18. Pedigrees• Autosomal: Not sex-linked Autosomal Dominant How can we tell? Human Chromosomes
  19. 19. Pedigrees Autosomal Recessive How can we tell?
  20. 20. Pedigrees Sex-Linked How can we tell? Is the X-linked dominant or recessive?
  21. 21. Pedigree Analysis Case Study• Read family information• Put family name at the top of your whiteboard• Make a pedigree for the entire family• Label names of all family members that you know• Make a key for the possible genotypes and phenotypes of your trait. Label as many individual genotypes on the pedigree that you can.• Shade in the people that have the trait• Identify the Patterns in the Pedigree and write the following answers on your whiteboard: – Is the trait dominant or recessive? – Does the trait show up in every generation? Or, does the trait skip a generation? – Does the trait affect males/females equally? Or, Does the trait only affect males? Or, only females? – Does your trait fit our model? (why or why not?) If not, what rule(s) need to change, or what new rules do you need to explain how this trait is inherited?• YOUR PATTERN SHOULD SUPPORT YOUR ANSWER.•

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