This document provides strategies for strengthening needs statements in grant proposals using data and research. It outlines four strategies: 1) using specific and local data; 2) presenting data in an easy-to-follow way from "big to small"; 3) citing relevant research; and 4) helping the reader follow the argument and draw conclusions. Examples are provided for each strategy to illustrate how to incorporate compelling local data, cluster and sequence information clearly, support needs with outside studies, and explicitly state the implications of the presented evidence.