1. NATURAL COURSE
OF HIV/AIDS
By
ES NYEMBE

2. Stage 1 - Primary
• Short, flu-like illness - occurs one to six weeks after
infection
• Mild symptoms
• Infected person can infect other people

4. Stage 2 - Asymptomatic

6. Stage 4 - HIV AIDS
 The immune system
weakens too much as CD4
cells decrease in number.

7. TB & HIV CO-INFECTION
TB is the most common opportunistic infection in HIV and the first cause of
mortality in HIV infected patients (10-30%)
10 million patients co-infected in the world.
Immunosuppression induced by HIV modifies the clinical presentation of
TB :
1.
2.
3.
Subnormal clinical and roentgen presentation
High rate of MDR/XDR
High rate of treatment failure and relapse (5% vs < 1% in HIV)