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W E L C O M E
THE SENSE OF
VISION
A PRESENTATION BY:
MUHAMMMAD SOHAIB
RANA ZAIN ALI
PRESENTED TO:
PROF. WAJIHAASIF
TABLE OF CONTENTS
9/25/2022
COURTESY: ZAIN & SOHAIB 2
 Anatomy of eye
 Neural function of eye
 Photochemistry of vision
COURTESY: ZAIN & SOHAIB 9/25/2022
3
COURTESY: ZAIN & SOHAIB 9/25/2022
4
 Superior oblique muscle
 Inferior oblique muscle
 Superior rectus muscle
 Inferior rectus muscle
COURTESY: ZAIN & SOHAIB
EXTRAOCULAR MUSCLES
9/25/2022
5
COURTESY: ZAIN & SOHAIB 9/25/2022
6
 PRINCIPAL FOCUS
The point on the axis of a lens or mirror to which parallel rays of
light converge or from which they appear to diverge after refraction
or reflection.
 FOCAL LENGTH
Focal length of a lens is the distance between centre of lens and
focal point . Focal point is a point on principal axis , at which light
rays meet after refraction through lens.
COURTESY: ZAIN & SOHAIB 9/25/2022
7
Human eye is composed of four refractive interfaces:
1. The interface between the air and the anterior surface of cornea.
2. The interface between the posterior surface of cornea and the aqueous humor.
3. The interface between the aqueous humor and the anterior surface of the lens.
4. The interface between the posterior surface of the lens and the vitreous humor.
COURTESY: ZAIN & SOHAIB
IMAGE FORMATION IN HUMAN
EYE
9/25/2022
8
ACCOMMODATION
COURTESY: ZAIN & SOHAIB 9/25/2022
9
NEAR SIGHTEDNESS
 FAR SIGHTEDNESS
COURTESY: ZAIN & SOHAIB
DISEASES
9/25/2022
10
 DEUTERANOPIA ( Green )
 PROFTANOPIA ( Red )
 TRITANOPIA ( Blue )
9/25/2022
COURTESY: ZAIN & SOHAIB 11
COLOR BLINDNESS
9/25/2022
COURTESY: ZAIN & SOHAIB 12
1. LAYERS OF RETINA
 Pigmented layer
• Melanin pigment
• Prevent light reflection & enhances visual acuity
• Also stores Vitamin A
• Albinos lack melanin
 Layers of rods and cones
 Outer nuclear layer
 Outer plexiform layer
 Inner nuclear layer
 Inner plexiform layer
 Ganglionic layer
 Layer of optic nerve fibers
 Inner limiting membrane
ANATOMY AND FUNCTIONS OF
RETINA
COURTESY: ZAIN & SOHAIB 9/25/2022
13
SNELLEN EYE CHART
9/25/2022
COURTESY: ZAIN & SOHAIB 14
2. FOVEAL REGION
• Minute area in the centre of retina ( 1 mm2 )
• Cones with slender and long bodies
• Rods are absent
• Blood vessels, ganglion cells, inner nuclear layer of cells and plexiform
layer are displaced aside
• Provides acute and detailed vision
COURTESY: ZAIN & SOHAIB
ANATOMY AND FUNCTIONS OF
RETINA
9/25/2022
15
3. RODS & CONES
• Rods are longer and narrower ( 2 – 5 mm in peripheral retina)
• Cones are shorter and broader ( 5 – 8 mm in peripheral retina )
• Rods contain Rhodopsin
• Cones contain Iodopsin ( color pigment )
 PARTS OF RODS AND CONES
o Outer segment
• Discs of folded cell membrane ( 1000 )
• Photochemical pigment ( 40% )
o Inner segment
• Mitochondria which provides energy
• Other cytoplasmic organelles
o Synaptic body
• Connect to neuronal cells, horizontal and bipolar cells
COURTESY: ZAIN & SOHAIB
ANATOMY AND FUNCTIONS OF
RETINA
9/25/2022
16
COURTESY: ZAIN & SOHAIB
NEURAL FUNCTION OF RETINA
 THE PHOTORECEPTORS ( RODS AND CONES )
• Transmit signals to outer plexiform layer
• Synapse with bipolar and horizontal cells
 THE HORIZONTIAL CELLS
• Transmit signals horizontally from rods and cones to
bipolar cells
 THE BIPOLAR CELLS
• Transmit signals from rods & horizontal cells to inner
plexiform layer
• Synapse with ganglion cells and amacrine cells
 THE AMACRINE CELLS
• Transmit signals from bipolar cells to amacrine cells
 THE GANGLION CELLS
• Transmit output signals from retina through optic
nerve to brain
 THE INTERPLEXIFORM CELLS
• Transmit signals in retrograde direction ( from inner
to outer plexiform layer )
• Inhibitory signals control the lateral spread of signals
by horizontal cells
• Control degree of contrast in the visual image
9/25/2022
17
COURTESY: ZAIN & SOHAIB
PHOTOCHEMISTRY OF VISION
Fig: The rhodopsin - retinal visual cycle
9/25/2022
18
EXCITATION OF ROD WHEN RHODOPSIN IS
ACTIVATED BY LIGHT
• The rod receptor potential is
Hyperpolarization, Not Depolarization
COURTESY: ZAIN & SOHAIB
PHOTOCHEMISTRY OF VISION
9/25/2022
19
COURTESY: ZAIN & SOHAIB 9/25/2022
20
WHY DO WE HAVE TWO EYES?
9/25/2022
COURTESY: ZAIN & SOHAIB 21
COURTESY: ZAIN & SOHAIB 9/25/2022
22

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The sense of vision-1.pptx

  • 1. W E L C O M E THE SENSE OF VISION A PRESENTATION BY: MUHAMMMAD SOHAIB RANA ZAIN ALI PRESENTED TO: PROF. WAJIHAASIF
  • 2. TABLE OF CONTENTS 9/25/2022 COURTESY: ZAIN & SOHAIB 2  Anatomy of eye  Neural function of eye  Photochemistry of vision
  • 3. COURTESY: ZAIN & SOHAIB 9/25/2022 3
  • 4. COURTESY: ZAIN & SOHAIB 9/25/2022 4
  • 5.  Superior oblique muscle  Inferior oblique muscle  Superior rectus muscle  Inferior rectus muscle COURTESY: ZAIN & SOHAIB EXTRAOCULAR MUSCLES 9/25/2022 5
  • 6. COURTESY: ZAIN & SOHAIB 9/25/2022 6
  • 7.  PRINCIPAL FOCUS The point on the axis of a lens or mirror to which parallel rays of light converge or from which they appear to diverge after refraction or reflection.  FOCAL LENGTH Focal length of a lens is the distance between centre of lens and focal point . Focal point is a point on principal axis , at which light rays meet after refraction through lens. COURTESY: ZAIN & SOHAIB 9/25/2022 7
  • 8. Human eye is composed of four refractive interfaces: 1. The interface between the air and the anterior surface of cornea. 2. The interface between the posterior surface of cornea and the aqueous humor. 3. The interface between the aqueous humor and the anterior surface of the lens. 4. The interface between the posterior surface of the lens and the vitreous humor. COURTESY: ZAIN & SOHAIB IMAGE FORMATION IN HUMAN EYE 9/25/2022 8
  • 9. ACCOMMODATION COURTESY: ZAIN & SOHAIB 9/25/2022 9
  • 10. NEAR SIGHTEDNESS  FAR SIGHTEDNESS COURTESY: ZAIN & SOHAIB DISEASES 9/25/2022 10
  • 11.  DEUTERANOPIA ( Green )  PROFTANOPIA ( Red )  TRITANOPIA ( Blue ) 9/25/2022 COURTESY: ZAIN & SOHAIB 11 COLOR BLINDNESS
  • 13. 1. LAYERS OF RETINA  Pigmented layer • Melanin pigment • Prevent light reflection & enhances visual acuity • Also stores Vitamin A • Albinos lack melanin  Layers of rods and cones  Outer nuclear layer  Outer plexiform layer  Inner nuclear layer  Inner plexiform layer  Ganglionic layer  Layer of optic nerve fibers  Inner limiting membrane ANATOMY AND FUNCTIONS OF RETINA COURTESY: ZAIN & SOHAIB 9/25/2022 13
  • 15. 2. FOVEAL REGION • Minute area in the centre of retina ( 1 mm2 ) • Cones with slender and long bodies • Rods are absent • Blood vessels, ganglion cells, inner nuclear layer of cells and plexiform layer are displaced aside • Provides acute and detailed vision COURTESY: ZAIN & SOHAIB ANATOMY AND FUNCTIONS OF RETINA 9/25/2022 15
  • 16. 3. RODS & CONES • Rods are longer and narrower ( 2 – 5 mm in peripheral retina) • Cones are shorter and broader ( 5 – 8 mm in peripheral retina ) • Rods contain Rhodopsin • Cones contain Iodopsin ( color pigment )  PARTS OF RODS AND CONES o Outer segment • Discs of folded cell membrane ( 1000 ) • Photochemical pigment ( 40% ) o Inner segment • Mitochondria which provides energy • Other cytoplasmic organelles o Synaptic body • Connect to neuronal cells, horizontal and bipolar cells COURTESY: ZAIN & SOHAIB ANATOMY AND FUNCTIONS OF RETINA 9/25/2022 16
  • 17. COURTESY: ZAIN & SOHAIB NEURAL FUNCTION OF RETINA  THE PHOTORECEPTORS ( RODS AND CONES ) • Transmit signals to outer plexiform layer • Synapse with bipolar and horizontal cells  THE HORIZONTIAL CELLS • Transmit signals horizontally from rods and cones to bipolar cells  THE BIPOLAR CELLS • Transmit signals from rods & horizontal cells to inner plexiform layer • Synapse with ganglion cells and amacrine cells  THE AMACRINE CELLS • Transmit signals from bipolar cells to amacrine cells  THE GANGLION CELLS • Transmit output signals from retina through optic nerve to brain  THE INTERPLEXIFORM CELLS • Transmit signals in retrograde direction ( from inner to outer plexiform layer ) • Inhibitory signals control the lateral spread of signals by horizontal cells • Control degree of contrast in the visual image 9/25/2022 17
  • 18. COURTESY: ZAIN & SOHAIB PHOTOCHEMISTRY OF VISION Fig: The rhodopsin - retinal visual cycle 9/25/2022 18
  • 19. EXCITATION OF ROD WHEN RHODOPSIN IS ACTIVATED BY LIGHT • The rod receptor potential is Hyperpolarization, Not Depolarization COURTESY: ZAIN & SOHAIB PHOTOCHEMISTRY OF VISION 9/25/2022 19
  • 20. COURTESY: ZAIN & SOHAIB 9/25/2022 20
  • 21. WHY DO WE HAVE TWO EYES? 9/25/2022 COURTESY: ZAIN & SOHAIB 21
  • 22. COURTESY: ZAIN & SOHAIB 9/25/2022 22