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Development of Basophils Hematopoiesis.pdf
- 1. 10 µm
Basophil #2
Histology Guide
CHAPTER 8 - HEMATOPOIESIS Share
MH 034bhr Bone Marrow Smear
asophilic Metamyelocyte
yelocyte matures into a basophilic
12 to 17 µm diameter)
ted, kidney shaped (50% of cell) of mostly
n
ges from blue-gray to pink-gray
ophilic, specific granules
c granules
able of mitosis
amyelocyte (60x) [+]
Band Basophil
The basophilic metamyelocyte matures into a band basophil.
Smaller cells (10 to 12 µm diameter)
Nucleus is elongated and often has a horseshoe-like ("U")
appearance that contains heterochromatin
Cytoplasm is a pale blue-pink
Many very basophilic, specific granules
Few azurophilic granules
No longer capable of mitosis
No band basophil is found on this slide.
Basophil
The band basophil develops into a mature basophil. Basophils
mediate inflammatory responses.
Rare white blood cells (<1%)
Smaller cells (10 to 12 µm diameter)
Nucleus bilobed or S-shaped
Cytoplasm is a pale blue-pink
Many very basophilic, specific granules
Few azurophilic granules
No longer capable of mitosis
Examples:
Basophil #1 (60x) [+]
Basophil #2 (60x) [–]
Basophil #3 (60x) [+]
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© 2005-2023. T. Clark Brelje and Robert L. Sorenson
66 x 66 µm
60x