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ALL ABOUT ESSENTIAL OIL
Volatile Oils
• Essential oils
• volatilize and distilled in steam
• chemically and physically different from fixed
oils
– not glyceryl esters of fatty acids
– do not leaves permanent grease spot in paper
– not saponified with alkali
– not become rancid but on exposure to air and light
becomes oxidized and resinify
• frequently associated with other substances like
gums, resins
Volatile Oils
• they are secreted by oil glands, oil cells, secretory
ducts, glandular hairs, modified parenchyma
cells, oil tubes (vittae), lysigenous or
schizogenous passages
• Use: therapeutically - administered by inhalation
(eucalyptus oil), orally (peppermint oil), gargle
and mouthwash (thymol oil), transdermal
(lavender, rosemary, bergamot - aromatherapy)
• with phenol content - antiseptic, carminative
(clove, thyme) antispasmodic
• anti-bacterial, food preservative
Volatile Oils
• generally mixtures of hydrocarbons and
oxygenated compounds derived from
hydrocarbons
• the odor and taste is mainly determined by the
oxygenated constituents which is immiscible in
water but more soluble in alcohol
• many of them are terpenoids in origin with some
containing aromatic derivatives
Volatile Oils
• Evaluation
– preliminary examination: odor and taste
• taste, if diluted with a sugar solution in ethanol as
prescribed by BP)
– Physical measurements: optical rotation, relative
density, refractive index
– to determine individual proportions of components -
Gas Chromatography
– volatile oil content in crude drugs - determined by
distillation (clavenger method)
Volatile Oils
• Methods of obtaining volatile oils
1. Direct steam distillation
- disadv: hydrolysis of certain components
decomposition at high temperatures
2. Expression - those that cannot be distilled due to
decomposition
a. ecuelle method
b. sponge method
3. Enfleurage - fat absorbs oil
4. Extraction - solvent systems and distilled at 50oC
5. Rectification - second distillation in steam and
frees oil from resin and other impurities
Volatile Oils
• volatile oils’ chemical constituents are divided
into 2 classes based on their biosynthetic
origin:
– 1. Terpenoid derivatives - acetate - mevalonic acid
pathway
– 2. Aromatic compounds - shikimmic acid - phenyl
propanoid pathway
• many volatile oils are largely monoterpenoids
and others phenylterpenoids
• constituents are responsible for their
characteristic odor, taste, flavor and therapeutic
properties
Oil of Turpentine
Synonym: spirit of turpentine, rectified oil of
turpentine
Origin: rectified volatile oil distilled from the
oleoresin of Pinus palustris (Pinaceae)
Constituents: terpene ((+), (-)α,(-) β – pinene,
camphene)
Use: externally – counterirritant, rubefacient
- fragrance, flavor, vitamins, insecticide
Note: - rarely given internally
- for inhalation – terebene is preferred (terebene is
prepared from oil of turpentine and cols sulfuric
acid --- converts pinene to inactive diterpene
(±limonene)
Ma. Asuncion S. Cobar:
Hydrocarbons
Canada turpentine
Synonym: Canada balsam
Origin: oleoresin from the stem of Abies
balsamea (Pinaceae)
Constituent: contains 23 – 24% volatile oil
Use: use as microscopic mount
Note:
Oil occurs in schizogenous ducts and large
cavities
Pumilio Oil
Synonym: Dwarf Mountain Pine oil
Origin: oil obtained from the fresh leaves of Pinus
mago var. pumilio (Pineaceae)
Constituents: terpenes and sesquiterpenes (L-
camphene, β – pinene, dipentene, borneol,
cadinene, monoterpene with bornyl acetate
Use:
- decongestant inhalant
- prep. of compound thymol glycerin
- constituent of Zinc undecenoate dusting powder
Oil of Cade
Origin: oil obtained from the destructive distillation
of the woody portions of Juniperus oxycedras
(Cupressaceae)
Constituent: sesquiterpene – cadinene
- phenolic compounds – guaiacol, ethyl guaiacol
and cresol
Use: veterinary purposes (skin diseases)
Cubeb NF X (1955)
Synonym: tailed pepper, java pepper, cubeba
Origin: dreid nearly full – grown but unripe fruit of
Piper cubeba (Piperaceae)
Constituents:
- 20 – 28% volatile oil containing terpenes and
sesquiterpenes
- cubebin – inodorous crystalline substance
- cubebic acid – white amorphous substance
- Amorphous resin
Use: stimulant, carminative, condiment
Pepper NF V (1926)
Synonym: Black pepper, Malisa, Paminta
Origin: dried unripe fruits of Piper nigrum
(Piperaceae)
Constituents:
- terpene – limonene, sabinene, camphene, β –
bisabolene, β – caryophylene, β – pinene,
thujone
- alkaloids – piperine and piperitine (pungency)
Use: once used in the treatment of gonorrhea and
chronic bronchitis
- condiment
Pepper
Note:
- stimulate thermal receptors and increases secretion
of saliva and gastric mucosa
- may ease the nicotine withdrawal syndrome during
smoking
white pepper – removal of the outer part of the pericarp
Lupulin (Humulus NF VII 1942)
Synonym: lupulinic Glands, Hop Strobile,
lupulin (drug), common hops
Origin: glandular hairs separated from the
strobile of Humulus lupulus (Cannabinaceae
Constituents:
- humulene – α – acids (phlorogluctinol
derivative)
- lupulone – β - acid
- 2 – methyl – 3 – butene – 2 ol (sedative –
hypnotic property
Lupulin
Use:
- bitter tonic, mild anti – bacterial (gm +)
- sedative (treat neuralgia, insomnia, nervous tension
etc.)
- mild diuretic, appetite stimulant, digestive aid
- Preserve beer
Adverse Effect: CNS – sedation; Resp. – bronchial irritation;
Skin – contact dermatitis
Interactions: CNS depressants – additive
Phenothiazine – type antipsychotic - additive
Peppermint NF18(1995)
Synonym: Brandy Mint, Menta Inglesa
Origin: dried leaves of Mentha piperita (Lamiaceae)
Constituents:
- oil distilled with steam from the fresh leaves,
partially or wholly dementholized
- menthol, menthone, acetaldehyde, deimethyl
sulfide, isovaleric aldehyde, pinene, limonene,
terpinene, piperitone, pulegone, carvone
- 2 – acetyl – 4 – isopropenyl pyridine - odor
Use: Pharmaceutical aid(flavor), carminative,
stimulant, counterirritant
- commercial importance, flavor for
confectionery(chewing gum)
Ma. Asuncion S. Cobar:
Alcohol
Peppermint
– Antibacterial, antiviral
– Enteric – antispasmodic, antiflatulence
Interactions: Cal. Blockers -  effect
• Adverse:
– gallstones, obstructed bile ducts, gall bladder
inflammation, severe liver damage
– Face and nostrils of infants and children
Note:
Japanese Peppermint (Mentha canadensis var.
piperascens) contains 70-90% menthol
- higher in menthol yield but inferior in flavor
compared to peppermint oil
Peppermint
Menthol
- used as topical antipruritic in burns and
sunburn preparations
- counterirritant, antiseptic, stimulant
- internally, depressant effect to the heart
Cardamon NF 14 (1985)
Synonym: Ceylon or Malabar cardamon
Origin: dried nearly ripe fruit of Elettaria
cardamomum var. minuscula (Zingiberaceae)
- dried ripe seeds recently removed from the
capsules of Elettaria cardamomum
(Zingiberaceae)
Constituents:
- volatile oil – linalol and terpenes
- cineol ,  - terponyl acetate
Use:
- flavoring agent in curries, cake, manufacture of
liqueurs
- form of Cpd. Tincture of Cardamon
- anti- viral
Sage
Synonym: Garden sage Dalmatian sage, meadow
sage
Origin: dried leaves of Salvia officinalis
(Lamiaceae)
Constituents: 50% thujone with cineole, borneol,
diterpenes, camphor
Use: infusion: mouthwash, gargle (antiseptic and
astringent)
- topical – itching – insect bite, herpes lesions,
shingles, psoriasis
- vaginal douche – yeast infection
- Prevent hair loss and preserve hair color
Sage
– Has cholinergic activity – treatment of
Alzheimer’s disease
– Mild antioxidant property
• Adverse: seizure
• Interaction: disufiram
– Those with epileptic history
Savin
Synonym: Savin Tops, Horse Savin Tops
Origin: young shoots of Juniperus sabina
(Cupressaceae)
Constituent:
- terpene alcohol – sabinol
- podophyllotoxin, coumarin, savinin
Use: powerful irritant both internally and externally
Sandalwood Oil NF 7 (1942)
Synonym: white sandalwood
Origin: heartwood of Santalinum album
(Santalaceae)
Constituent:
- sesquiterpene – α, β – santalol
Use:
- mainly used in perfumery
- urinary antiseptic, stimulant, treatment of
bronchitis
Note: chemoprotective action on liver carcinogenesis
(mice)
Juniper NF 10 (1955)
Synonym: Horse savin berries, juniper berries
Origin: dried ripe fruits of Juniperus communis
(Cupressaceae)
Constituents: volatile oil contains α - pinene,
camphene, sesquiterpene – cadinene,
terpin –4-ol
Uses: diuretic, atiseptic, UTI, kidney stones
- falvoring agent – gin, bitters, liqueurs
Note:
prolonged use of commercial oil causes kidney damage due
to high terpene and low proportion of terpin - 4-ol
Juniper NF 10 (1955)
Adverse: kidney failure
Interactions:
Antidiabetics – potentiation
antihypertensives – interfere with blood pressure
diuretics – potentiation – hypokalemia
ginseng, fenugreek – additive
Cucumber, dandelion, horsetail - additive
Coriander oil NF 11(1960)
Synonym: culantro, Uansoy, Fruto de Cilantro,
Chinese parsley
Origin: dried nearly ripe fruit of Coriandrum
sativum (Apiaceae)
Constituents:
volatile oil contains (+) linalool (coriandrol),
small amts of α - pinene, γ- terpinene, limonene,
p-cymene
Use:
spice, flavoring agent, carminative, enhance
appetite, treat dyspepsia, diarrhea
treatment of cough, chest pain, fever and measles
Coriander oil
- aromatherapy – soothing effect, improve blood
circulation
Note:
unripe fruit has a mousy odor
Adverse: anaphylactic reactions
Interactions: sun exposure - risk of photosensitivity
Otto of Rose NF 8 (1947)
Synonym: Rose oil Attar of Rose, Oleum Rosae
Origin: dried fresh flowers of Rosa gallica, R.
damascens, R. centifolia (Rosaceae)
Constituents:
volatile oil contains geraniol, (-) citronellol,
nerol, 2-phenylethanol
Use:
perfume
Note: oil id semi – solid, liquid portion - alcohols
Geranium
Synonym: Malvarosa
Origin: the whole plant except the roots of
Pelargonium graveolens (Geraniaceae)
Constituents:
volatile oil contains geraniol, citronellol,
limonene
Use: antidepressant, antiseptic, fingicidal, styptic
flavoring agent
Note: - Indian or Turkish geranium (Palmarosa)
- citronella oil
- freshly cutted or partially dried leaves of Cymbopogon
winterianus, C. nardus (Poaceae)
- citronellol, geraniol
- perfume, insect repellant
Lavender Oil NF XVI (1985)
Synonym: Lavanda, Espliego , Foreign oil
Origin: fresh flowering tops Lavandula officinalis,
L. augustifolia (Lamiaceae)
Constituents: volatile oil contains linalyl acetate,
linalool, cineol, terpin-4-ol
Use: perfume, toiletry (to mask disagreeable odor)
- pharmaceutically in the anti-arthropod prep.
(Gamma Benzene Hexachloride)
- treatment of flatulent dyspepsia
- topically - rheumatic pain
- aromatherapy
Ma. Asuncion S. Cobar:
Ester
Lavender
oil exert sedative effect orally, topically and inhaled
doses (non-toxic – up to 5g/kg)
Adverse – respiratory depression
Interaction: CNS depressants – potentiate
alcohol - potentiate
Ma. Asuncion S. Cobar:
Ester
Rosemary
Synonym: Hoja de Romero, Romero, compass
plant, polar plant
Origin: Flowering tops of leafy twigs of
Rosmarinus officinalis (Lamiaceae)
Constituents: fresh sample, the volatile oil contains
cineole, borneol, camphor, bornyl acetate, linalol
- leaves contain triterpene alcohols (α, β -
amyrin), rosmarinic acid, diosmin
Use: perfumery, component of soap liniment
- aromatherapy
- insect repellant
Rosemary Oil – NF XII (1985)
Rosemary
Note:
oil is adulterated with Spanish eucalyptus oil, camphor oil,
turpentine fractions
Adverse: seizures at high doses
Interactions: sunlight – topical cream
Valerian
Synonym: Summer Heliotrope, All Heal Root
Origin: dried rhizome and roots of Valeriana
officinalis (Valerianaceae)
Constituents:
volatile oil contains bornyl acetate, bornyl
isovalerate, valerenic acid, valerenolic acid,
acetoxyvalerenolic acid, bornyl valerate
valeric acid
- lipo - iridoid principle - valepotriate
Use: tea, carminative, antispasmodic (nervous
disorders, perfume
Allied drugs:
1. Indian Valerian - Valeriana wallichii
2. Japanese Valerian - Valeriana augustifolia
Valerian
Interactions:
barbiturates, benzodiazepine – additive
hops, kava, passion flower - potentiate
Oleum Valerianae USP VI (1882)
Gaultheria
Synonym: Wintergreen, Boxberry, Teaberry
Origin: dried leaves of Gaultheria procumbens
(Ericaceae)
Constituents:
volatile oil contains methyl salicylate
Use: diuretic, astringent, stimulant, rheumatoid
arthritis
- used in diarrhea
Note:
- methyl salicylate can be obtained from Betula lenta
(Betulaceae)
- enzymatic hydrolysis of gaultherin – methyl salicylate
Gaultheria
Methyl salicylate NF 18 (1995)
Adverse: pulmonary edema and collapse, renal failure,
liver failure, metabolic acidosis
Intrerations:
Anticoagulants, antiplatelets - bleeding
Antidiabetics, salicylates - hypoglycemic
Bergamot
Synonym:
Origin: rind of the fresh fruit of Citrus aurantium
var. bergania (Rutaceae)
Constituent: linalyl acetate, linalol
Use: used aromatically for stress related conditions
- anti-depressant, antiseptic
- combined with eucalyptus and carrier oil to
relieve symptoms of shingles and cold sores
- suppresses irritation caused by chicken pox
Note:
- oil is phototoxic
Bergamot oil NF XI (1960)
Cinnamon NF XVI(1985)
Synonym: Corteza de Canela
Origin: dried bark of the stem and branches of
Cinnamomum zeylanicum (Ceylon Cinnamon), C.
cassia or aromaticum (Cassia Cinnamon), C.
Laureirii (Saigon Cinnamon) (Lauraceae)
Constituents:
volatile oil contains cinnamic aldehyde, limonene,
p-cymene, linalool, β - caryophylene, eugenol and
mannitol
Use: flavoring agent, carminative, pungent aromatic,
antiseptic, powerful germicide against
Aspergillus
Cassia oil – NF 14(1985)
Ceylon oil – NF 11 (1960)
Ma. Asuncion S. Cobar:
Aldehyde
Sweet Orange USP 15(1955)
Synonym: Naranja Dulce, Naranja de Valencia
Origin: fresh outer rind of the non-artificially
colored ripe fruit of Citrus aurantium var.
sinensis (Rutaceae)
Constituents:
violexanthin, D - limonene, citral, citronellal
Use: flavoring agent, carminative
Caution: do not use oil with terebinthinate odor
Orange Flower Oil – C. aurantium partially
expanded flower
Bitter Orange
Synonym: Neroli Oil
Origin: fresh outer rind of the non-artificially colored
ripe fruit of Citrus aurantium var. amara
(Rutaceae)
Constituents:
flavone glycosides – naringin, neohesperidin
Vol oil – limonene, jasmone, linalyl acetate,
geranyl acetate, citronellyl acetate
Uses:
Stimulate appetite and digestion,
relieve flatulence, Antifungal, gargle
Lemon Peel
Synonym: limon
Origin: yellow outer rind of the fresh ripe fruit of
Citrus limon (Rutaceae)
Constituents:
terpene (limonene), aldehyde (citral, citronellal)
Coumarins, flavonoids (rutin, hesperidin)
Use: flavor, stimulant, stomachic, perfume
Note: oil is prepared from hand method, machine or
distilled
adulterant: oil of turpentine
Lemongrass BPC 1968
Synonym: tanglad, citronella, fevergrass
Origin: whole plant of Cymbopogon citratus /nardus
(Poaceae)
Constituents:
citral, citronellal, myrcene, geraniol
cymbopogol
Use:
flavor, antispasmodic, analgesic, treatment of
nervous and GI disorders
Mosquito repellant, mask fishy odor
Food additive
Bitter Almond oil NF X (1955)
Origin: dried ripe kernel (deprived of fixed oil) of
Prunus amygdalus var. amara (Rosaceae)
Constituents:
benzaldehyde, HCN
Use:
sedative, cough remedies
- not taken internally
Bitter Oil is intended for medicinal use and neither
it or its solution be used or sold as flavoring agent
Spearmint NF 14 (1985)
Synonym: ordinary garden mint, Lamb or Mackerel
Mint, Hierba buena (Mentha arvensis)
Origin: dried leaves and flowering tops of Mentha
spicata (M. viridis), M. cardiaca (Lamiaceae)
Constituents:
(-) carvone, (-)limonene, phellandrene
Use:
carminative, stimulant, nervine, corrective,
flavoring agent
Note: oil formation depends on age, time of
collection, chemical varieties or hybridization
Ma. Asuncion S. Cobar:
Ketone
Caraway NF 14 (1985)
Synonym: Alcarahueya, Karawya, Carum
Origin: dried ripe fruit(cremocarp) of Carum carvi
(Apiaceae)
Constituents:
(+) carvone, terpene (d-limonene or carvene)
dihydrocarvone, carveol, deihydrocarveol
Use:
culinary purpose, flavor, carminative, weak
antispasmodic
promote lactation, stimulate appetite
Dill
Synonym:dill herb, dill weed
Origin: dried ripe fruit(cremocarp) of Anethum
graveolens (Apiaceae)
Constituents:
carvone, limonene
Use:
carminative, flavor, used in infant’s gripe water
antispasmodic, bacteriostatic
- avoid sun exposure
Buchu NF X (1955)
Synonym: Bucco, Bucha
Origin: dried leaves of Barosma betulina, B.
crenulata, B. serratifolia (Rutaceae)
Constituents:
volatile oil contains pulegone, limonene,
menthone, diosmin
in distilled oil - diosphenol (buchu camphor)
formed at room temperature
Use:
diuretic, urinary antiseptic, carminative, cystitis
Adverse: stomach, bowel and kidney irritation
Interaction: anticoagulants - enhanced
Absinthium NF 4 (1916)
Synonym: green ginger, absinthe, Wormwood
Origin: dried leaves and flowering tops of Artemisia
absinthium (Asteraceae)
Constituents:
volatile oil contains thujone anf flavones
bitter principles: absinthine, artabsin (lactone
sesquiterpene)
artabsinolide A,B,C
Use: promote appetite, strengthening effect in the
treatment of colds and influenza, expulsion of
roundworms
Lovage
Synonym: lavose, maggi plant, sea parsley
Origin: dried rhizome and roots of Levisticum
officinale (Apiaceae)
Constituents:
volatile oil contains, Ligusticum lactone,
ligustilide, 3-butylphthalide
Use:
herbal remedy, antimicrobial, treatment of
dyspepsia, cystitis, mouthwash (tonsilitis)
stimulates salivation and gastric secretion
diuretic (pedal edema)
Interaction: anticoagulants, warfarin – potentiate
sunlight
Matricaria
Synonym: Flor de Manzanilla, Rosas de Japon,
German or Hungarian Chamomile
Origin: dried flower heads of Matricaria recutita
(Asteraceae)
Constituents:
contains a blue volatile oil mainly of
sesquiterpenes α - bisabolol, chamazulene and
farnesene
Use:
anti-inflammatory, spasmolytic property, ulcer -
protective property
Tea – sedation and relaxation
Interaction: warfarin
Matricaria
Allied drug:
Tanacetum parthenium, Chrysanthenum
parthenium or feverfew USP 7 !894)
- also known as bachelor’s button
- parthenolide (germacronolide)
- inhibits protaglandin synthesis, platelet
aggregation, release of serotonin from
platelets etc.
Thyme NFX (1955)
Synonym: Common or Garden Thyme, Tremocillo
Origin: dried leaves and flowering tops of Thymus
vulgaris (Lamiaceae)
Constituents:
thymol, carvacrol, rosmarinic acid
Uses:
antiseptic, antitussive, expectorant, spasmolytic,
condiment, antibacterial
Oil – NF 12(1965)
Ma. Asuncion S. Cobar:
Phenol
Clove NF 11 (1960)
Synonym: Clavo de Especia, Clavo aromatico,
Clavillo
Origin: the dried flower buds of Syzygium
aromaticum (Eugenia caryophyllus) (Myrtaceae)
Constituents:
volatile oil contains eugenol(phenol) with
acetyleugenol, sesquiterpene (α, and β - caryo -
phyllene), eugenyl acetate
Use: flavoring agent, stimulant, aromatic and
antiseptic
dental analgesic, antibacterial (gm + and - )
Clove NF 11 (1960)
• store in well – filled, air – tight container
protected from light and heat
Adverse: liver failure, pulmonary toxicity
Interactions: inhibit platelet aggregation
Myrcia Oil NF 11 (1060)
Synonym: Bay Oil
Origin: leaves of Pimenta racemosa (Myrtaceae)
Constituents:
eugenol, methyl eugenol, chavicol
Use:
perfume, Constituent of Cpd. Myrcia Spirit (Bay
Rum), pharmaceutical necessity
Ajowan
Synonym: Carum capticum
Origin: dried seeds of Trachyspermum ammi
(Apiaceae)
Constituent: Thymol
Uses:
carminative, diuretic, stomach disorder, chest
infections, epilepsy, hypotensive
Allspice NF V (1926)
Synonym: pimiento, Jamaican pepper, clove pepper
Origin: dried nearly ripe fruit of Pimenta dioica /
officinalis (Myrtaceae)
Constituents:
eugenol, caryophyllene, cineole, leviphellandrene
Use:
condiment (enhance the taste of food)
dental analgesic, aid in indigestion
massage oil (aromatherapy)
analgesic – arthritis, muscle spasm
Anise
Synonym: Aniseed, Matalahuga
Origin: dried ripe fruits (cremocarp) of Pimpinella
anisum (Apiaceae)
Constituents:
volatile oil contains anethole, chavicol, methyl
ether
Use: flavor, aromatic stimulant, carminative,
treatment of coughs and colds
Note: allied drug - Star Anise
Ma. Asuncion S. Cobar:
Phenolic Ether
Star Anise
A) Chinese Star- anise
- Sanke’
- dried fruits of Illicium verum (Magnoliaceae -
Illiciaceae)
- fruit has 8 follicles
- constituent: anethole
- use: flavoring agent, carminative
Star Anise
b) Japanese Star - anise
- Shikimmi
- dried fruit of Illicium religiosum
(Magnoliaceae)
- 2 follicles are smaller like a beak
- anthole, skimmin, skimmic acid
- no use due to its toxicity
Fennel
Synonym: Sweet Fennel fruit, Haras, Anis
Origin: dried ripe fruit of Foeniculum vulgare
var. dulce (Apiaceae)
Constituents:
volatile oil contains anethole, fenchone
Use:
aromatic stimulant, corrective of purgatives
Adulterant: Bitter Fennel (Foeniculum
vulgare var. vulgare) a, small fruit with no
anethole but with fenchone and phellandrene
Cajeput
Origin: fresh leaves of Melaleuca leucodendron
(Myrtaceae)
Constituents:
cineole, terpineol, terpineol acetate
Use:
used internally and externally as a stimulant
treatment of several parasitic conditions
Camphor
Synonym: Natural camphor
Origin: wood of Cinnamomum camphora
(Lauraceae)
Constituents:
volatile oil contains camphor, safrole, borneol,
heliotropic
Use:
externally as a rubefacient
internally - mild antiseptic and carminative
formerly used in the manufacture of celluloid
Camphor
Synthetic camphor - American turpentine
Allied drugs:
1. Borneo camphor - Drybalanops aromatico
(Dipterocarpaceae)
2. Ngai camphor - Blumea balsamifera
(Asteraceae)
3. Artemisia - levorotaory camphor
Parsley
Synonym: garden parsley, persely
Origin: the whole plant of Petroselinum sativum
(Apiaceae)
Constituents:
apiole (dimethylsafrole), apigenin (flavonol
glycoside)
Use:
condiment
treatment of indigestion, flatulence and dyspepsia
Nutmeg
Synonym: Myristica, Nuez de Banda
Origin: dried kernel of Myristica fragrans
(Myristicaceae) deprived of its seed coat and
arillode and with or without thin coating of
lime.
Consituents:
volatile oil contains myristicin, elemicin, safrole,
eugenol, d-camphene, dipentene
Use: flavoring agent, carminative, condiment
Indian medicine, used in the treatment of infantile
diarrhea
Nutmeg
Mace (Banda mace)
- dried arillus or arillode of Myristica fragrans
(Myristicaceae)
- contains volatile oil similar to nutmeg and
phenolic compounds - dihydrodiisoeugenol and
5’ - methoxydehydrodiisoeugenol
- significant antibacterial property
Note: Nutmeg is known for its psychoactive and
hallucinogenic properties
Sassafras
Synonym: Agûe Tree
Origin: dried bark of the roots of Sassfras albidum
or variifolium (Lauraceae)
Constituents:
safrole, tannic acid --- sassafrid red, terpenes
Use:
carminative, aromatic, stimulant, flavor,
corrective
Chenopodium
Synonym: American Wormseed. Alpaseotes
Origin: dried fruit of Chenopodium ambrosoides
var. anthelmintica (Chenopodiaceae)
Constituents:
ascaridole, unsaturated terpene peroxide
Use:
anthelmintic (roundworms, hookworms and
intestinal ameobae)
Ma. Asuncion S. Cobar:
Oxide/ Peroxide
Eucalyptus
Synonym: Blue Gum leaves, Gum wood, Fever
Tree
Origin: the dried scythe - shaped leaf of Eucalyptus
globulus (Myrtaceae)
Constituents:
volatile oil contains, cineole, phellandrene
Use:
alleviate symptoms of nasopharyngeal infections,
treat coughs and decongestant
internally and externally - expectorant
externally : treat sore muscles and rheumatism
Tea - Tree Oil
Synonym: paperbark tree
Origin: dried leaves and terminal branches of
Melaleuca alternifolia (Myrtaceae)
Constituents
cineole and terpin - 4 -ol
Use:
antiseptic (skin diseases), anti-fungal
THANK YOU
VISHNU MOHAN M
9995638126

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ESSENTIAL OIL VISHNU MOHAN 9995638126 ].ppt

  • 2. Volatile Oils • Essential oils • volatilize and distilled in steam • chemically and physically different from fixed oils – not glyceryl esters of fatty acids – do not leaves permanent grease spot in paper – not saponified with alkali – not become rancid but on exposure to air and light becomes oxidized and resinify • frequently associated with other substances like gums, resins
  • 3. Volatile Oils • they are secreted by oil glands, oil cells, secretory ducts, glandular hairs, modified parenchyma cells, oil tubes (vittae), lysigenous or schizogenous passages • Use: therapeutically - administered by inhalation (eucalyptus oil), orally (peppermint oil), gargle and mouthwash (thymol oil), transdermal (lavender, rosemary, bergamot - aromatherapy) • with phenol content - antiseptic, carminative (clove, thyme) antispasmodic • anti-bacterial, food preservative
  • 4. Volatile Oils • generally mixtures of hydrocarbons and oxygenated compounds derived from hydrocarbons • the odor and taste is mainly determined by the oxygenated constituents which is immiscible in water but more soluble in alcohol • many of them are terpenoids in origin with some containing aromatic derivatives
  • 5. Volatile Oils • Evaluation – preliminary examination: odor and taste • taste, if diluted with a sugar solution in ethanol as prescribed by BP) – Physical measurements: optical rotation, relative density, refractive index – to determine individual proportions of components - Gas Chromatography – volatile oil content in crude drugs - determined by distillation (clavenger method)
  • 6. Volatile Oils • Methods of obtaining volatile oils 1. Direct steam distillation - disadv: hydrolysis of certain components decomposition at high temperatures 2. Expression - those that cannot be distilled due to decomposition a. ecuelle method b. sponge method 3. Enfleurage - fat absorbs oil 4. Extraction - solvent systems and distilled at 50oC 5. Rectification - second distillation in steam and frees oil from resin and other impurities
  • 7. Volatile Oils • volatile oils’ chemical constituents are divided into 2 classes based on their biosynthetic origin: – 1. Terpenoid derivatives - acetate - mevalonic acid pathway – 2. Aromatic compounds - shikimmic acid - phenyl propanoid pathway • many volatile oils are largely monoterpenoids and others phenylterpenoids • constituents are responsible for their characteristic odor, taste, flavor and therapeutic properties
  • 8.
  • 9. Oil of Turpentine Synonym: spirit of turpentine, rectified oil of turpentine Origin: rectified volatile oil distilled from the oleoresin of Pinus palustris (Pinaceae) Constituents: terpene ((+), (-)α,(-) β – pinene, camphene) Use: externally – counterirritant, rubefacient - fragrance, flavor, vitamins, insecticide Note: - rarely given internally - for inhalation – terebene is preferred (terebene is prepared from oil of turpentine and cols sulfuric acid --- converts pinene to inactive diterpene (±limonene) Ma. Asuncion S. Cobar: Hydrocarbons
  • 10. Canada turpentine Synonym: Canada balsam Origin: oleoresin from the stem of Abies balsamea (Pinaceae) Constituent: contains 23 – 24% volatile oil Use: use as microscopic mount Note: Oil occurs in schizogenous ducts and large cavities
  • 11. Pumilio Oil Synonym: Dwarf Mountain Pine oil Origin: oil obtained from the fresh leaves of Pinus mago var. pumilio (Pineaceae) Constituents: terpenes and sesquiterpenes (L- camphene, β – pinene, dipentene, borneol, cadinene, monoterpene with bornyl acetate Use: - decongestant inhalant - prep. of compound thymol glycerin - constituent of Zinc undecenoate dusting powder
  • 12. Oil of Cade Origin: oil obtained from the destructive distillation of the woody portions of Juniperus oxycedras (Cupressaceae) Constituent: sesquiterpene – cadinene - phenolic compounds – guaiacol, ethyl guaiacol and cresol Use: veterinary purposes (skin diseases)
  • 13. Cubeb NF X (1955) Synonym: tailed pepper, java pepper, cubeba Origin: dreid nearly full – grown but unripe fruit of Piper cubeba (Piperaceae) Constituents: - 20 – 28% volatile oil containing terpenes and sesquiterpenes - cubebin – inodorous crystalline substance - cubebic acid – white amorphous substance - Amorphous resin Use: stimulant, carminative, condiment
  • 14. Pepper NF V (1926) Synonym: Black pepper, Malisa, Paminta Origin: dried unripe fruits of Piper nigrum (Piperaceae) Constituents: - terpene – limonene, sabinene, camphene, β – bisabolene, β – caryophylene, β – pinene, thujone - alkaloids – piperine and piperitine (pungency) Use: once used in the treatment of gonorrhea and chronic bronchitis - condiment
  • 15. Pepper Note: - stimulate thermal receptors and increases secretion of saliva and gastric mucosa - may ease the nicotine withdrawal syndrome during smoking white pepper – removal of the outer part of the pericarp
  • 16. Lupulin (Humulus NF VII 1942) Synonym: lupulinic Glands, Hop Strobile, lupulin (drug), common hops Origin: glandular hairs separated from the strobile of Humulus lupulus (Cannabinaceae Constituents: - humulene – α – acids (phlorogluctinol derivative) - lupulone – β - acid - 2 – methyl – 3 – butene – 2 ol (sedative – hypnotic property
  • 17. Lupulin Use: - bitter tonic, mild anti – bacterial (gm +) - sedative (treat neuralgia, insomnia, nervous tension etc.) - mild diuretic, appetite stimulant, digestive aid - Preserve beer Adverse Effect: CNS – sedation; Resp. – bronchial irritation; Skin – contact dermatitis Interactions: CNS depressants – additive Phenothiazine – type antipsychotic - additive
  • 18. Peppermint NF18(1995) Synonym: Brandy Mint, Menta Inglesa Origin: dried leaves of Mentha piperita (Lamiaceae) Constituents: - oil distilled with steam from the fresh leaves, partially or wholly dementholized - menthol, menthone, acetaldehyde, deimethyl sulfide, isovaleric aldehyde, pinene, limonene, terpinene, piperitone, pulegone, carvone - 2 – acetyl – 4 – isopropenyl pyridine - odor Use: Pharmaceutical aid(flavor), carminative, stimulant, counterirritant - commercial importance, flavor for confectionery(chewing gum) Ma. Asuncion S. Cobar: Alcohol
  • 19. Peppermint – Antibacterial, antiviral – Enteric – antispasmodic, antiflatulence Interactions: Cal. Blockers -  effect • Adverse: – gallstones, obstructed bile ducts, gall bladder inflammation, severe liver damage – Face and nostrils of infants and children Note: Japanese Peppermint (Mentha canadensis var. piperascens) contains 70-90% menthol - higher in menthol yield but inferior in flavor compared to peppermint oil
  • 20. Peppermint Menthol - used as topical antipruritic in burns and sunburn preparations - counterirritant, antiseptic, stimulant - internally, depressant effect to the heart
  • 21. Cardamon NF 14 (1985) Synonym: Ceylon or Malabar cardamon Origin: dried nearly ripe fruit of Elettaria cardamomum var. minuscula (Zingiberaceae) - dried ripe seeds recently removed from the capsules of Elettaria cardamomum (Zingiberaceae) Constituents: - volatile oil – linalol and terpenes - cineol ,  - terponyl acetate Use: - flavoring agent in curries, cake, manufacture of liqueurs - form of Cpd. Tincture of Cardamon - anti- viral
  • 22. Sage Synonym: Garden sage Dalmatian sage, meadow sage Origin: dried leaves of Salvia officinalis (Lamiaceae) Constituents: 50% thujone with cineole, borneol, diterpenes, camphor Use: infusion: mouthwash, gargle (antiseptic and astringent) - topical – itching – insect bite, herpes lesions, shingles, psoriasis - vaginal douche – yeast infection - Prevent hair loss and preserve hair color
  • 23. Sage – Has cholinergic activity – treatment of Alzheimer’s disease – Mild antioxidant property • Adverse: seizure • Interaction: disufiram – Those with epileptic history
  • 24. Savin Synonym: Savin Tops, Horse Savin Tops Origin: young shoots of Juniperus sabina (Cupressaceae) Constituent: - terpene alcohol – sabinol - podophyllotoxin, coumarin, savinin Use: powerful irritant both internally and externally
  • 25. Sandalwood Oil NF 7 (1942) Synonym: white sandalwood Origin: heartwood of Santalinum album (Santalaceae) Constituent: - sesquiterpene – α, β – santalol Use: - mainly used in perfumery - urinary antiseptic, stimulant, treatment of bronchitis Note: chemoprotective action on liver carcinogenesis (mice)
  • 26. Juniper NF 10 (1955) Synonym: Horse savin berries, juniper berries Origin: dried ripe fruits of Juniperus communis (Cupressaceae) Constituents: volatile oil contains α - pinene, camphene, sesquiterpene – cadinene, terpin –4-ol Uses: diuretic, atiseptic, UTI, kidney stones - falvoring agent – gin, bitters, liqueurs Note: prolonged use of commercial oil causes kidney damage due to high terpene and low proportion of terpin - 4-ol
  • 27. Juniper NF 10 (1955) Adverse: kidney failure Interactions: Antidiabetics – potentiation antihypertensives – interfere with blood pressure diuretics – potentiation – hypokalemia ginseng, fenugreek – additive Cucumber, dandelion, horsetail - additive
  • 28. Coriander oil NF 11(1960) Synonym: culantro, Uansoy, Fruto de Cilantro, Chinese parsley Origin: dried nearly ripe fruit of Coriandrum sativum (Apiaceae) Constituents: volatile oil contains (+) linalool (coriandrol), small amts of α - pinene, γ- terpinene, limonene, p-cymene Use: spice, flavoring agent, carminative, enhance appetite, treat dyspepsia, diarrhea treatment of cough, chest pain, fever and measles
  • 29. Coriander oil - aromatherapy – soothing effect, improve blood circulation Note: unripe fruit has a mousy odor Adverse: anaphylactic reactions Interactions: sun exposure - risk of photosensitivity
  • 30. Otto of Rose NF 8 (1947) Synonym: Rose oil Attar of Rose, Oleum Rosae Origin: dried fresh flowers of Rosa gallica, R. damascens, R. centifolia (Rosaceae) Constituents: volatile oil contains geraniol, (-) citronellol, nerol, 2-phenylethanol Use: perfume Note: oil id semi – solid, liquid portion - alcohols
  • 31. Geranium Synonym: Malvarosa Origin: the whole plant except the roots of Pelargonium graveolens (Geraniaceae) Constituents: volatile oil contains geraniol, citronellol, limonene Use: antidepressant, antiseptic, fingicidal, styptic flavoring agent Note: - Indian or Turkish geranium (Palmarosa) - citronella oil - freshly cutted or partially dried leaves of Cymbopogon winterianus, C. nardus (Poaceae) - citronellol, geraniol - perfume, insect repellant
  • 32. Lavender Oil NF XVI (1985) Synonym: Lavanda, Espliego , Foreign oil Origin: fresh flowering tops Lavandula officinalis, L. augustifolia (Lamiaceae) Constituents: volatile oil contains linalyl acetate, linalool, cineol, terpin-4-ol Use: perfume, toiletry (to mask disagreeable odor) - pharmaceutically in the anti-arthropod prep. (Gamma Benzene Hexachloride) - treatment of flatulent dyspepsia - topically - rheumatic pain - aromatherapy Ma. Asuncion S. Cobar: Ester
  • 33. Lavender oil exert sedative effect orally, topically and inhaled doses (non-toxic – up to 5g/kg) Adverse – respiratory depression Interaction: CNS depressants – potentiate alcohol - potentiate Ma. Asuncion S. Cobar: Ester
  • 34. Rosemary Synonym: Hoja de Romero, Romero, compass plant, polar plant Origin: Flowering tops of leafy twigs of Rosmarinus officinalis (Lamiaceae) Constituents: fresh sample, the volatile oil contains cineole, borneol, camphor, bornyl acetate, linalol - leaves contain triterpene alcohols (α, β - amyrin), rosmarinic acid, diosmin Use: perfumery, component of soap liniment - aromatherapy - insect repellant Rosemary Oil – NF XII (1985)
  • 35. Rosemary Note: oil is adulterated with Spanish eucalyptus oil, camphor oil, turpentine fractions Adverse: seizures at high doses Interactions: sunlight – topical cream
  • 36. Valerian Synonym: Summer Heliotrope, All Heal Root Origin: dried rhizome and roots of Valeriana officinalis (Valerianaceae) Constituents: volatile oil contains bornyl acetate, bornyl isovalerate, valerenic acid, valerenolic acid, acetoxyvalerenolic acid, bornyl valerate valeric acid - lipo - iridoid principle - valepotriate Use: tea, carminative, antispasmodic (nervous disorders, perfume Allied drugs: 1. Indian Valerian - Valeriana wallichii 2. Japanese Valerian - Valeriana augustifolia
  • 37. Valerian Interactions: barbiturates, benzodiazepine – additive hops, kava, passion flower - potentiate Oleum Valerianae USP VI (1882)
  • 38. Gaultheria Synonym: Wintergreen, Boxberry, Teaberry Origin: dried leaves of Gaultheria procumbens (Ericaceae) Constituents: volatile oil contains methyl salicylate Use: diuretic, astringent, stimulant, rheumatoid arthritis - used in diarrhea Note: - methyl salicylate can be obtained from Betula lenta (Betulaceae) - enzymatic hydrolysis of gaultherin – methyl salicylate
  • 39. Gaultheria Methyl salicylate NF 18 (1995) Adverse: pulmonary edema and collapse, renal failure, liver failure, metabolic acidosis Intrerations: Anticoagulants, antiplatelets - bleeding Antidiabetics, salicylates - hypoglycemic
  • 40. Bergamot Synonym: Origin: rind of the fresh fruit of Citrus aurantium var. bergania (Rutaceae) Constituent: linalyl acetate, linalol Use: used aromatically for stress related conditions - anti-depressant, antiseptic - combined with eucalyptus and carrier oil to relieve symptoms of shingles and cold sores - suppresses irritation caused by chicken pox Note: - oil is phototoxic Bergamot oil NF XI (1960)
  • 41. Cinnamon NF XVI(1985) Synonym: Corteza de Canela Origin: dried bark of the stem and branches of Cinnamomum zeylanicum (Ceylon Cinnamon), C. cassia or aromaticum (Cassia Cinnamon), C. Laureirii (Saigon Cinnamon) (Lauraceae) Constituents: volatile oil contains cinnamic aldehyde, limonene, p-cymene, linalool, β - caryophylene, eugenol and mannitol Use: flavoring agent, carminative, pungent aromatic, antiseptic, powerful germicide against Aspergillus Cassia oil – NF 14(1985) Ceylon oil – NF 11 (1960) Ma. Asuncion S. Cobar: Aldehyde
  • 42. Sweet Orange USP 15(1955) Synonym: Naranja Dulce, Naranja de Valencia Origin: fresh outer rind of the non-artificially colored ripe fruit of Citrus aurantium var. sinensis (Rutaceae) Constituents: violexanthin, D - limonene, citral, citronellal Use: flavoring agent, carminative Caution: do not use oil with terebinthinate odor Orange Flower Oil – C. aurantium partially expanded flower
  • 43. Bitter Orange Synonym: Neroli Oil Origin: fresh outer rind of the non-artificially colored ripe fruit of Citrus aurantium var. amara (Rutaceae) Constituents: flavone glycosides – naringin, neohesperidin Vol oil – limonene, jasmone, linalyl acetate, geranyl acetate, citronellyl acetate Uses: Stimulate appetite and digestion, relieve flatulence, Antifungal, gargle
  • 44. Lemon Peel Synonym: limon Origin: yellow outer rind of the fresh ripe fruit of Citrus limon (Rutaceae) Constituents: terpene (limonene), aldehyde (citral, citronellal) Coumarins, flavonoids (rutin, hesperidin) Use: flavor, stimulant, stomachic, perfume Note: oil is prepared from hand method, machine or distilled adulterant: oil of turpentine
  • 45. Lemongrass BPC 1968 Synonym: tanglad, citronella, fevergrass Origin: whole plant of Cymbopogon citratus /nardus (Poaceae) Constituents: citral, citronellal, myrcene, geraniol cymbopogol Use: flavor, antispasmodic, analgesic, treatment of nervous and GI disorders Mosquito repellant, mask fishy odor Food additive
  • 46. Bitter Almond oil NF X (1955) Origin: dried ripe kernel (deprived of fixed oil) of Prunus amygdalus var. amara (Rosaceae) Constituents: benzaldehyde, HCN Use: sedative, cough remedies - not taken internally Bitter Oil is intended for medicinal use and neither it or its solution be used or sold as flavoring agent
  • 47. Spearmint NF 14 (1985) Synonym: ordinary garden mint, Lamb or Mackerel Mint, Hierba buena (Mentha arvensis) Origin: dried leaves and flowering tops of Mentha spicata (M. viridis), M. cardiaca (Lamiaceae) Constituents: (-) carvone, (-)limonene, phellandrene Use: carminative, stimulant, nervine, corrective, flavoring agent Note: oil formation depends on age, time of collection, chemical varieties or hybridization Ma. Asuncion S. Cobar: Ketone
  • 48. Caraway NF 14 (1985) Synonym: Alcarahueya, Karawya, Carum Origin: dried ripe fruit(cremocarp) of Carum carvi (Apiaceae) Constituents: (+) carvone, terpene (d-limonene or carvene) dihydrocarvone, carveol, deihydrocarveol Use: culinary purpose, flavor, carminative, weak antispasmodic promote lactation, stimulate appetite
  • 49. Dill Synonym:dill herb, dill weed Origin: dried ripe fruit(cremocarp) of Anethum graveolens (Apiaceae) Constituents: carvone, limonene Use: carminative, flavor, used in infant’s gripe water antispasmodic, bacteriostatic - avoid sun exposure
  • 50. Buchu NF X (1955) Synonym: Bucco, Bucha Origin: dried leaves of Barosma betulina, B. crenulata, B. serratifolia (Rutaceae) Constituents: volatile oil contains pulegone, limonene, menthone, diosmin in distilled oil - diosphenol (buchu camphor) formed at room temperature Use: diuretic, urinary antiseptic, carminative, cystitis Adverse: stomach, bowel and kidney irritation Interaction: anticoagulants - enhanced
  • 51. Absinthium NF 4 (1916) Synonym: green ginger, absinthe, Wormwood Origin: dried leaves and flowering tops of Artemisia absinthium (Asteraceae) Constituents: volatile oil contains thujone anf flavones bitter principles: absinthine, artabsin (lactone sesquiterpene) artabsinolide A,B,C Use: promote appetite, strengthening effect in the treatment of colds and influenza, expulsion of roundworms
  • 52. Lovage Synonym: lavose, maggi plant, sea parsley Origin: dried rhizome and roots of Levisticum officinale (Apiaceae) Constituents: volatile oil contains, Ligusticum lactone, ligustilide, 3-butylphthalide Use: herbal remedy, antimicrobial, treatment of dyspepsia, cystitis, mouthwash (tonsilitis) stimulates salivation and gastric secretion diuretic (pedal edema) Interaction: anticoagulants, warfarin – potentiate sunlight
  • 53. Matricaria Synonym: Flor de Manzanilla, Rosas de Japon, German or Hungarian Chamomile Origin: dried flower heads of Matricaria recutita (Asteraceae) Constituents: contains a blue volatile oil mainly of sesquiterpenes α - bisabolol, chamazulene and farnesene Use: anti-inflammatory, spasmolytic property, ulcer - protective property Tea – sedation and relaxation Interaction: warfarin
  • 54. Matricaria Allied drug: Tanacetum parthenium, Chrysanthenum parthenium or feverfew USP 7 !894) - also known as bachelor’s button - parthenolide (germacronolide) - inhibits protaglandin synthesis, platelet aggregation, release of serotonin from platelets etc.
  • 55. Thyme NFX (1955) Synonym: Common or Garden Thyme, Tremocillo Origin: dried leaves and flowering tops of Thymus vulgaris (Lamiaceae) Constituents: thymol, carvacrol, rosmarinic acid Uses: antiseptic, antitussive, expectorant, spasmolytic, condiment, antibacterial Oil – NF 12(1965) Ma. Asuncion S. Cobar: Phenol
  • 56. Clove NF 11 (1960) Synonym: Clavo de Especia, Clavo aromatico, Clavillo Origin: the dried flower buds of Syzygium aromaticum (Eugenia caryophyllus) (Myrtaceae) Constituents: volatile oil contains eugenol(phenol) with acetyleugenol, sesquiterpene (α, and β - caryo - phyllene), eugenyl acetate Use: flavoring agent, stimulant, aromatic and antiseptic dental analgesic, antibacterial (gm + and - )
  • 57. Clove NF 11 (1960) • store in well – filled, air – tight container protected from light and heat Adverse: liver failure, pulmonary toxicity Interactions: inhibit platelet aggregation
  • 58. Myrcia Oil NF 11 (1060) Synonym: Bay Oil Origin: leaves of Pimenta racemosa (Myrtaceae) Constituents: eugenol, methyl eugenol, chavicol Use: perfume, Constituent of Cpd. Myrcia Spirit (Bay Rum), pharmaceutical necessity
  • 59. Ajowan Synonym: Carum capticum Origin: dried seeds of Trachyspermum ammi (Apiaceae) Constituent: Thymol Uses: carminative, diuretic, stomach disorder, chest infections, epilepsy, hypotensive
  • 60. Allspice NF V (1926) Synonym: pimiento, Jamaican pepper, clove pepper Origin: dried nearly ripe fruit of Pimenta dioica / officinalis (Myrtaceae) Constituents: eugenol, caryophyllene, cineole, leviphellandrene Use: condiment (enhance the taste of food) dental analgesic, aid in indigestion massage oil (aromatherapy) analgesic – arthritis, muscle spasm
  • 61. Anise Synonym: Aniseed, Matalahuga Origin: dried ripe fruits (cremocarp) of Pimpinella anisum (Apiaceae) Constituents: volatile oil contains anethole, chavicol, methyl ether Use: flavor, aromatic stimulant, carminative, treatment of coughs and colds Note: allied drug - Star Anise Ma. Asuncion S. Cobar: Phenolic Ether
  • 62. Star Anise A) Chinese Star- anise - Sanke’ - dried fruits of Illicium verum (Magnoliaceae - Illiciaceae) - fruit has 8 follicles - constituent: anethole - use: flavoring agent, carminative
  • 63. Star Anise b) Japanese Star - anise - Shikimmi - dried fruit of Illicium religiosum (Magnoliaceae) - 2 follicles are smaller like a beak - anthole, skimmin, skimmic acid - no use due to its toxicity
  • 64. Fennel Synonym: Sweet Fennel fruit, Haras, Anis Origin: dried ripe fruit of Foeniculum vulgare var. dulce (Apiaceae) Constituents: volatile oil contains anethole, fenchone Use: aromatic stimulant, corrective of purgatives Adulterant: Bitter Fennel (Foeniculum vulgare var. vulgare) a, small fruit with no anethole but with fenchone and phellandrene
  • 65. Cajeput Origin: fresh leaves of Melaleuca leucodendron (Myrtaceae) Constituents: cineole, terpineol, terpineol acetate Use: used internally and externally as a stimulant treatment of several parasitic conditions
  • 66. Camphor Synonym: Natural camphor Origin: wood of Cinnamomum camphora (Lauraceae) Constituents: volatile oil contains camphor, safrole, borneol, heliotropic Use: externally as a rubefacient internally - mild antiseptic and carminative formerly used in the manufacture of celluloid
  • 67. Camphor Synthetic camphor - American turpentine Allied drugs: 1. Borneo camphor - Drybalanops aromatico (Dipterocarpaceae) 2. Ngai camphor - Blumea balsamifera (Asteraceae) 3. Artemisia - levorotaory camphor
  • 68. Parsley Synonym: garden parsley, persely Origin: the whole plant of Petroselinum sativum (Apiaceae) Constituents: apiole (dimethylsafrole), apigenin (flavonol glycoside) Use: condiment treatment of indigestion, flatulence and dyspepsia
  • 69. Nutmeg Synonym: Myristica, Nuez de Banda Origin: dried kernel of Myristica fragrans (Myristicaceae) deprived of its seed coat and arillode and with or without thin coating of lime. Consituents: volatile oil contains myristicin, elemicin, safrole, eugenol, d-camphene, dipentene Use: flavoring agent, carminative, condiment Indian medicine, used in the treatment of infantile diarrhea
  • 70. Nutmeg Mace (Banda mace) - dried arillus or arillode of Myristica fragrans (Myristicaceae) - contains volatile oil similar to nutmeg and phenolic compounds - dihydrodiisoeugenol and 5’ - methoxydehydrodiisoeugenol - significant antibacterial property Note: Nutmeg is known for its psychoactive and hallucinogenic properties
  • 71. Sassafras Synonym: Agûe Tree Origin: dried bark of the roots of Sassfras albidum or variifolium (Lauraceae) Constituents: safrole, tannic acid --- sassafrid red, terpenes Use: carminative, aromatic, stimulant, flavor, corrective
  • 72. Chenopodium Synonym: American Wormseed. Alpaseotes Origin: dried fruit of Chenopodium ambrosoides var. anthelmintica (Chenopodiaceae) Constituents: ascaridole, unsaturated terpene peroxide Use: anthelmintic (roundworms, hookworms and intestinal ameobae) Ma. Asuncion S. Cobar: Oxide/ Peroxide
  • 73. Eucalyptus Synonym: Blue Gum leaves, Gum wood, Fever Tree Origin: the dried scythe - shaped leaf of Eucalyptus globulus (Myrtaceae) Constituents: volatile oil contains, cineole, phellandrene Use: alleviate symptoms of nasopharyngeal infections, treat coughs and decongestant internally and externally - expectorant externally : treat sore muscles and rheumatism
  • 74. Tea - Tree Oil Synonym: paperbark tree Origin: dried leaves and terminal branches of Melaleuca alternifolia (Myrtaceae) Constituents cineole and terpin - 4 -ol Use: antiseptic (skin diseases), anti-fungal
  • 75. THANK YOU VISHNU MOHAN M 9995638126