This presentation discusses neonatal abstinence syndrome, which occurs when a newborn experiences withdrawal symptoms from exposure to addictive drugs in the womb. The presenter outlines the incidence, types, etiology, symptoms, exams/tests used for diagnosis, and management approaches for NAS. Regarding management, non-pharmacological interventions like swaddling and minimal stimulation are recommended initially. If symptoms are severe, pharmacological therapy using morphine, methadone or clonidine may be used. The roles of nurses in assessing exposed newborns, monitoring withdrawal, and coordinating multidisciplinary care are also reviewed. The presenter emphasizes the importance of prevention through screening, education, and treatment programs for pregnant women with substance use
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Neonatal abstinence syndrome
1. A PRESENTATION ON
NEONATAL ABSTINANCE
SYNDROME
BY
Mr VINU.K.S
ASSISSTANT PROFESSOR
PEDIATRIC DEPATMENT
NAINCY COLLEGE OF NURSING
NAINITAL
2. Neonatal abstinence syndrome
Neonatal abstinence syndrome (NAS) is a group of
problems that occur in a newborn who was exposed to
addictive opiate drugs while in the mother’s womb
8. Symptoms
The symptoms of neonatal abstinence syndrome depend
on:
The type of drug the mother used
How the body breaks down and clears the drug
How much of the drug she was taking
How long she used the drug
Whether the baby was born full-term or early (premature)
9. CNS dysfunction includes the following
features:
High-pitched cry
Restlessness, with sleep duration less than 1-3 hours after
feeding
Hyperactive reflexes
Jitteriness
Tremors
Hypertonia
Myoclonic jerks
Generalized convulsions
10. Metabolic, vasomotor, and respiratory
disturbances include the following features
Sweating
Fever
Mottling
Frequent yawning
Respiratory rate greater than 60 breaths per minute
without retractions
Sneezing (>3 times per interval)
Apnoea
Nasal flaring
11. GI dysfunction includes the following
features:
Excessive (frantic) sucking
Poor feeding
Hyperphagia, usually associated with poor weight gain
Regurgitation or projectile vomiting
Loose or watery stools
12. Alcohol-specific symptoms include the
following:
Neonates also exhibit irritability,
tremors,
seizures,
Opisthotonos, and abdominal distention.
13. Exams and Tests
History collection
Physical examination
Toxicology (drug) screen of urine and of first bowel
movements (meconium).
Finnegan scoring system
15. NAS Scoring Protocol
Initiate scoring within 2 hours of admission
Infants should not be awakened to obtain a score
Infants at risk of opiate withdrawal are assessed for signs
of withdrawal ½ to 1 hour after each feed
The scoring chart is designed for term infants.
Allowances must be made for infants who are preterm
16. Management
Treatment depends on :
the drug involved
The infants overall health and abstinence score
Whether the baby was born full-term or premature
17. Non-Pharmacologic Interventions NAS
TLC ( tender loving care )
Swaddling
Rocking
Minimal sensory or environmental stimulation
Maintain temperature stability
High caloric feed
Breastfeeding
19. Pharmacologic therapy NAS
Begin when 2-3 consecutive Finnegan scores are ≥8 or
when the sum of 3 consecutive Finnegan scores is ≥24
Based upon toxicology and clinical presentation initiate
drug therapy
20. Pharmacologic therapy NAS
Morphine or methadone are first-line opiates
Clonidine is a first line or adjunctive therapy used in
combo with an opiate for poly-substance exposure
21. Role of nurse
Assess the women prenatally.
Identify the prenatal substance use of women.
Identify women’s need.
Assessment of baby by using Finnegan scale for
withdrawal symptom.
22. Role of nurse
Assess the maternal well being and parenting skills.
Circulate the planned discharge plan to a multidisciplinary
care team.
Medical and psycho social assessment of mother and baby
23. Prevention During Preconception period:
Promote awareness of effects of parental substance use.
No use of alcohol and opioids when planning and during
pregnancy.
Discuss all medicines and alcohol and tobacco use with
your health care provider
24. Prevention During Antenatal period:
Screening for pregnant women to identify the substance
abuse
provide the enhanced the referral services if necessary.
25. Prevention At birth:
Use consistent and effective protocols for identification of
substance exposed newborns
Make assurance for developmental child welfare services.
Editor's Notes
NAS due to prenatal or maternal use of substances that result in withdrawal symptoms in the newborn
postnatal NAS secondary to discontinuation of medications such as fentanyl or morphine used for pain therapy in the newborn.
Myoclonic jerks – sudden muscle contraction
Apnoea- temporary cessation of breath, specially during sleep.
Mottling – blotching of skin
Nasal flaring – widening of nostrils while breathing.
Opisthotonos – backward arching of head, neck and spine due to muscle spasm
History collection - Many other conditions can produce the same symptoms as neonatal abstinence syndrome. To help make a diagnosis, the health care provider will ask questions about the mother's drug use. The mother may be asked about which drugs she took during pregnancy, and when she last took them. The mother's urine may be screened for drugs as well.
Finnegan scoring system Neonatal abstinence syndrome scoring system, which assigns points based on each symptom and its severity. The infant's score can help determine treatment.
The optimal treatment for NAS has not been established. Primary treatment of neonatal symptoms related to prenatal substance exposure should be supportive because pharmacologic therapy can prolong hospitalization and exposes the infant to additional agents that are often not necessary. However, pharmacotherapy for infants with more severe expression of NAS is necessary to allow them to feed, sleep, gain weight, and interact with caregivers. Opioids are currently considered the first-line therapy. Second-line therapy has been phenobarbital. Phenobarbital has been effective for the treatment of opioid withdrawal seizures and polydrug exposure.
Clonidine – alpha 2 adrenergic agonist ,which will stimulate the alpha 2 receptors in brain which reduce the peripheral vascular resistance and thus decrease the BP
Methadone – its mu opioid antagonist
Morphin-pail reliever.
Should do the medical and psycho social assessment of mother and baby before discharge that indicate a stable condition.