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Pinaka XT
Dr Vijayant Govinda Gupta
Andrologist and Urologist
New Delhi India
Dr Vijayant G Gupta
• MBBS UCMS DU
• MS MAMC DU
• MCh Urology PGI Chandigarh
• Pvt Practice Since 2016
• Andrology Fellowships
• Denver, New York, Istanbul,
Seoul, Guangzhou, HongKong
Govinda Medicenter
• Largest Volume Andrology Practice in
New Delhi
• Highest Number of Penile Implants in
India
• Highest Number of Circumcisions in
India
35 Countries in 1 Clinic in 1 Year
Pinaka XT
Something for Everyone
Nano Curcumin
Curcumin is the major yellow pigment found in ordinary turmeric
Erectile Dysfunction
• Improves Blood Flow
• Repairs Circulation / Tissue
• Prevents inflammation
• Improves effect of Sildenafil /
Tadalafil
• Adjuvant to PRP and LiSWT
Molecular signalling of a novel curcumin derivative
versus Tadalafil in erectile dysfunction.
Abdel Aziz MT1, Rezq AM1, Atta HM1,2, Fouad
H1, Zaahkouk AM3, Ahmed HH1, Sabry D1, Yehia HM3.
Curcumin-Loaded Nanoparticles Treat Erectile
Dysfunction in a Rat Model of Type-2 Diabetes.
Draganski A1, Tar MT2, Villegas G2, Friedman JM1, Davies
KP3.
Sperm Count (Male Infertility)
• Improves Sperm Count
• Improves Sperm Motility
Curcumin nanomicelle improves semen parameters,
oxidative stress, inflammatory biomarkers, and
reproductive hormones in infertile men: A randomized
clinical trial. 2018
Alizadeh F1, Javadi M1, Karami AA2, Gholaminejad
F1, Kavianpour M3, Haghighian HK1.
Gynecology
• Endometriosis
• Pelvic inflammatory
Disease
• PCOD – Help in weight
Loss and Diabetes Control
The effects of curcumin supplementation on glycemic
status, lipid profile and hs-CRP levels in
overweight/obese women with polycystic ovary
syndrome: A randomized, double-blind, placebo-
controlled clinical trial.
Sohaei S1, Amani R2, Tarrahi MJ3, Ghasemi-Tehrani H4.
Curcumin and endometriosis: Review on potential
roles and molecular mechanisms.
Arablou T1, Kolahdouz-Mohammadi R2.
Ortho
• Osteoarthritis
Curcumin slows osteoarthritis progression and relieves osteoarthritis-associated pain
symptoms
Zhuo Zhang,
# Daniel J. Leong,
# Lin Xu, Zhiyong He, Angela Wang, Mahantesh Navati, Sun J. Kim, David M. Hirsh, John A. Hardin, Neil J. Cobelli, Joel M.
Friedman, and Hui B. Sun
Piperine
• Enhances the
bioavailability and
action of
Nanocurcumin
Omega 3 Fatty Acids
Studies suggest that by lowering oxidative stress and reducing
the degree of cavernosal fibrosis, omega-3 fatty acids protect
from erectile dysfunction
Corporal fibrosis is the main underlying etiology for ED in the
majority of patients
Regardless of age or etiology, 66% to 75% of cases of ED are
caused by corporal fibrosis and ultimately, CVOD. Therefore, if
the cause of CVOD itself can be prevented, then ED could
become a preventable condition. The results of our study
strengthen the evidence that omega-3 fatty acids work mainly
through its anti-oxidant and anti-inflammatory properties and
have an ameliorative function on fibrotic changes of
cavernosum tissue.
Effects of Omega-3 Fatty Acids on Erectile
Dysfunction
Ji Sung Shim, Dae Hee Kim, Jae Hyun Bae, and Du Geon Moon
Male Infertility
Female Infertility
L Arginine
• Precursor to NOS
• Improves ED
• Improves Effect of tadalafil
• Improves Exercise capacity
• Improves Antioxidant effect
L Carnitine
L Arginine plus Yohimbine can help Wpmen
Achieve Orgasm
Zinc and Selenium

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Pinaka XT - Nutraceutical for Erectile Dysfunction

  • 1. Pinaka XT Dr Vijayant Govinda Gupta Andrologist and Urologist New Delhi India
  • 2. Dr Vijayant G Gupta • MBBS UCMS DU • MS MAMC DU • MCh Urology PGI Chandigarh • Pvt Practice Since 2016 • Andrology Fellowships • Denver, New York, Istanbul, Seoul, Guangzhou, HongKong
  • 3. Govinda Medicenter • Largest Volume Andrology Practice in New Delhi • Highest Number of Penile Implants in India • Highest Number of Circumcisions in India
  • 4. 35 Countries in 1 Clinic in 1 Year
  • 6. Nano Curcumin Curcumin is the major yellow pigment found in ordinary turmeric
  • 7.
  • 8. Erectile Dysfunction • Improves Blood Flow • Repairs Circulation / Tissue • Prevents inflammation • Improves effect of Sildenafil / Tadalafil • Adjuvant to PRP and LiSWT Molecular signalling of a novel curcumin derivative versus Tadalafil in erectile dysfunction. Abdel Aziz MT1, Rezq AM1, Atta HM1,2, Fouad H1, Zaahkouk AM3, Ahmed HH1, Sabry D1, Yehia HM3. Curcumin-Loaded Nanoparticles Treat Erectile Dysfunction in a Rat Model of Type-2 Diabetes. Draganski A1, Tar MT2, Villegas G2, Friedman JM1, Davies KP3.
  • 9. Sperm Count (Male Infertility) • Improves Sperm Count • Improves Sperm Motility Curcumin nanomicelle improves semen parameters, oxidative stress, inflammatory biomarkers, and reproductive hormones in infertile men: A randomized clinical trial. 2018 Alizadeh F1, Javadi M1, Karami AA2, Gholaminejad F1, Kavianpour M3, Haghighian HK1.
  • 10. Gynecology • Endometriosis • Pelvic inflammatory Disease • PCOD – Help in weight Loss and Diabetes Control The effects of curcumin supplementation on glycemic status, lipid profile and hs-CRP levels in overweight/obese women with polycystic ovary syndrome: A randomized, double-blind, placebo- controlled clinical trial. Sohaei S1, Amani R2, Tarrahi MJ3, Ghasemi-Tehrani H4. Curcumin and endometriosis: Review on potential roles and molecular mechanisms. Arablou T1, Kolahdouz-Mohammadi R2.
  • 11. Ortho • Osteoarthritis Curcumin slows osteoarthritis progression and relieves osteoarthritis-associated pain symptoms Zhuo Zhang, # Daniel J. Leong, # Lin Xu, Zhiyong He, Angela Wang, Mahantesh Navati, Sun J. Kim, David M. Hirsh, John A. Hardin, Neil J. Cobelli, Joel M. Friedman, and Hui B. Sun
  • 12.
  • 13. Piperine • Enhances the bioavailability and action of Nanocurcumin
  • 14. Omega 3 Fatty Acids Studies suggest that by lowering oxidative stress and reducing the degree of cavernosal fibrosis, omega-3 fatty acids protect from erectile dysfunction Corporal fibrosis is the main underlying etiology for ED in the majority of patients Regardless of age or etiology, 66% to 75% of cases of ED are caused by corporal fibrosis and ultimately, CVOD. Therefore, if the cause of CVOD itself can be prevented, then ED could become a preventable condition. The results of our study strengthen the evidence that omega-3 fatty acids work mainly through its anti-oxidant and anti-inflammatory properties and have an ameliorative function on fibrotic changes of cavernosum tissue. Effects of Omega-3 Fatty Acids on Erectile Dysfunction Ji Sung Shim, Dae Hee Kim, Jae Hyun Bae, and Du Geon Moon
  • 17.
  • 18.
  • 19. L Arginine • Precursor to NOS • Improves ED • Improves Effect of tadalafil • Improves Exercise capacity • Improves Antioxidant effect
  • 20.
  • 21.
  • 23.
  • 24.
  • 25.
  • 26. L Arginine plus Yohimbine can help Wpmen Achieve Orgasm