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Brain and CranialBrain and Cranial
NervesNerves
TerminologyTerminology
 HemispheresHemispheres
 Gyrus (Gyri)Gyrus (Gyri)
 Sulcus (Sulci)Sulcus (Sulci)
 Longitudinal FissureLongitudinal Fissure
 VentriclesVentricles
– CSFCSF
Anatomy of the BrainAnatomy of the Brain
 CerebrumCerebrum
 CerebellumCerebellum
 DiencephalonDiencephalon
– ThalamusThalamus
– HyothalamusHyothalamus
 Brain StemBrain Stem
– MidbrainMidbrain
– PonsPons
– MedullaMedulla
oblongataoblongata
CerebrumCerebrum
 AnatomyAnatomy
– Frontal lobeFrontal lobe
– Parietal lobeParietal lobe
– Occipital lobeOccipital lobe
– Precentral gyrusPrecentral gyrus
– Postcentral gyrusPostcentral gyrus
 FunctionsFunctions
– Sensory cortexSensory cortex
– Motor cortexMotor cortex
– EmotionEmotion
– IntellectualIntellectual
processesprocesses
– AuditoryAuditory
– VisualVisual
– SpeechSpeech
CerebellumCerebellum
 AnatomyAnatomy
– HemispheresHemispheres
 FunctionsFunctions
– Compares intendedCompares intended
movement withmovement with
what is actuallywhat is actually
happeninghappening
– Smooth,Smooth,
coordinatedcoordinated
movementsmovements
– Posture/balancePosture/balance
Brain StemBrain Stem
 AnatomyAnatomy
– Medulla oblongataMedulla oblongata
– PonsPons
– MidbrainMidbrain
 FunctionsFunctions
– MedullaMedulla
 Relays motor andRelays motor and
sensory informationsensory information
 Regulates heartbeat,Regulates heartbeat,
breathing and bloodbreathing and blood
vessel dilationvessel dilation
– PonsPons
 Control breathingControl breathing
Protective CoveringsProtective Coverings
(Meninges)(Meninges)
 Dura materDura mater
Dense connective tissueDense connective tissue
 ArachnoidArachnoid
Nonvascular connective tissueNonvascular connective tissue
 Pia materPia mater
Highly vascularHighly vascular
Covers surface of the brain and spinal cord andCovers surface of the brain and spinal cord and
invaginates along cortical surface to forminvaginates along cortical surface to form
perivascular spacesperivascular spaces
Cerebral Spinal FluidCerebral Spinal Fluid
 Formed in the choroid plexusFormed in the choroid plexus
 Reabsorbed into saggittal sinus byReabsorbed into saggittal sinus by
arachnoid villiarachnoid villi
 Protects brain against concussiveProtects brain against concussive
traumatrauma
 removes waste productsremoves waste products
Foramen of Monro
Cranial NervesCranial Nerves
 I:I: OlfactoryOlfactory
 II:II: OpticOptic
 III:III: OculomotorOculomotor
 IV:IV: TrochlearTrochlear
 V:V: TrigeminalTrigeminal
 VI:VI: AbducensAbducens
 VII: FacialVII: Facial
 VIII:VestibulocochlearVIII:Vestibulocochlear
– AcousticAcoustic
 IX:IX: GlossopharyngealGlossopharyngeal
 X:X: VagusVagus
 XI:XI: AccessoryAccessory
 XII: HypoglossalXII: Hypoglossal
http://www.gwc.maricopa.edu/class/bio201/cn/cranial.htm
MnemonicMnemonic
 OnOn
 OldOld
 Olympus’Olympus’
 TowerTower
 TopTop
 AA
 FinFin
 AndAnd
 GermanGerman
 ViewedViewed
 AA
 HopHop
MNEMONICMNEMONIC
 OLFACTORYOLFACTORY
 OPTICOPTIC
 OCULOMOTOROCULOMOTOR
 TROCHLEARTROCHLEAR
 TRIGEMINALTRIGEMINAL
 ABDUCENSABDUCENS
 FACIALFACIAL
 VESTIBULOCOCHLEVESTIBULOCOCHLE
ARAR
 GLOSSOPHARYNGEGLOSSOPHARYNGE
ALAL
 VAGUSVAGUS
 ACCESSORYACCESSORY

 OHOH
 ONCEONCE
 ONEONE
 TAKESTAKES
 THETHE
 ANATOMYANATOMY
 FINALFINAL
 VERYVERY
 GOODGOOD
 VACATIONVACATION
 A-HEADA-HEAD
CN I: OLFACTORYCN I: OLFACTORY
 Cranial nerve ICranial nerve I
 Function:Function:
– smellsmell
 Clinical test forClinical test for
damage:damage:
– determine whetherdetermine whether
a person can smella person can smell
something aromaticsomething aromatic
CN II: OPTICCN II: OPTIC
 Cranial nerve IICranial nerve II
 Function:Function:
– visionvision
 Clinical test forClinical test for
damage:damage:
– tests peripheral visiontests peripheral vision
and visual acuityand visual acuity
 Effects of damage:Effects of damage:
– blindness in part or all ofblindness in part or all of
the visual fieldthe visual field
CNIII: OCULOMOTORCNIII: OCULOMOTOR
 Cranial nerve IIICranial nerve III
 Function:Function:
– eye movements, opening ofeye movements, opening of
eyelid, constriction of pupil,eyelid, constriction of pupil,
focusing, proprioceptionfocusing, proprioception
 Clinical tests for injury:Clinical tests for injury:
– differences in pupil size;differences in pupil size;
pupillary response to light; eyepupillary response to light; eye
trackingtracking
 Effects of damageEffects of damage
– dropping eyelid, dilated pupil,dropping eyelid, dilated pupil,
double visiondouble vision
CNIV: TROCHLEARCNIV: TROCHLEAR
 Cranial nerve IVCranial nerve IV
 Function: eye movementsFunction: eye movements
and proprioceptionand proprioception
 Clinical test for injury: abilityClinical test for injury: ability
to rotate eye inferolaterallyto rotate eye inferolaterally
 Effects of damage – doubleEffects of damage – double
vision, patient tilts headvision, patient tilts head
toward affected sidetoward affected side
CN V: TRIGEMINALCN V: TRIGEMINAL
 Cranial nerve VCranial nerve V
 Function: sensory nerve of theFunction: sensory nerve of the
faceface
 Clinical test for injury:Clinical test for injury:
– corneal reflex; sense ofcorneal reflex; sense of
touch, pain, and temperature;touch, pain, and temperature;
clench teeth; move mandibleclench teeth; move mandible
side to sideside to side
 Effects of damage:Effects of damage:
– loss of sensation andloss of sensation and
impaired chewingimpaired chewing
CN VI: ABDUCENS ANDCN VI: ABDUCENS AND
CN VII: FACIALCN VII: FACIAL
 Cranial Nerve VICranial Nerve VI
 Function: EyeFunction: Eye
movementsmovements
 Clinical test: lateral eyeClinical test: lateral eye
movementmovement
 Effects of damage:Effects of damage:
inability to rotate eyeinability to rotate eye
laterally; at rest – eyelaterally; at rest – eye
rotates mediallyrotates medially
because of action ofbecause of action of
antagonistic musclesantagonistic muscles
 Cranial Nerve VIICranial Nerve VII
 Function: facialFunction: facial
expression; sense ofexpression; sense of
tastetaste
 Clinical test: motorClinical test: motor
functions – close eyes,functions – close eyes,
smile, whistle, frown,smile, whistle, frown,
raise eyebrows; tasteraise eyebrows; taste
 Effects of damage:Effects of damage:
inability to control facialinability to control facial
muscles; distortedmuscles; distorted
sense of tastesense of taste
CN VIII:CN VIII:
VESTIBULOCOCHLEARVESTIBULOCOCHLEAR
 Cranial Nerve VIIICranial Nerve VIII
 Function: hearing and equilibriumFunction: hearing and equilibrium
 Clinical tests: test hearing, balance,Clinical tests: test hearing, balance,
and ability to walk a straight lineand ability to walk a straight line
 Effects of damage: deafness,Effects of damage: deafness,
dizziness, nausea, loss of balance,dizziness, nausea, loss of balance,
and nystagmusand nystagmus
CN IX:CN IX:
GLOSSOPHARANGEALGLOSSOPHARANGEAL
AND CN X: VAGUSAND CN X: VAGUS Cranial Nerve IXCranial Nerve IX
 Function: swallowing,Function: swallowing,
salivation, gagging; touch,salivation, gagging; touch,
pressure, taste, and painpressure, taste, and pain
sensations from tongue,sensations from tongue,
pharynx, and outer earpharynx, and outer ear
 Clinical tests: gag reflex,Clinical tests: gag reflex,
swallowing, and coughingswallowing, and coughing
 Effects of damage: difficultyEffects of damage: difficulty
swallowingswallowing
 Cranial Nerve XCranial Nerve X
 Function: swallowing; taste;Function: swallowing; taste;
speech; respiratory, CV, andspeech; respiratory, CV, and
GI regulation; sensations ofGI regulation; sensations of
hunger, fullness, andhunger, fullness, and
intestinal discomfortintestinal discomfort
 Clinical tests: test withClinical tests: test with
cranial nerve IXcranial nerve IX
 Effects of damage:Effects of damage:
hoarseness or loss of voice;hoarseness or loss of voice;
impaired swallowing and GIimpaired swallowing and GI
motilitymotility
CN XI: ACCESSORYCN XI: ACCESSORY
ANDAND
CN XII: HYPOGLOSSALCN XII: HYPOGLOSSAL Cranial Nerve XICranial Nerve XI
 Function: swallowing; head,Function: swallowing; head,
neck, and shoulderneck, and shoulder
movementsmovements
 Clinical tests: rotate headClinical tests: rotate head
and shrug shoulders againstand shrug shoulders against
resistanceresistance
 Effects of damage: impairedEffects of damage: impaired
movement of head, neck,movement of head, neck,
and shoulders; paralysis ofand shoulders; paralysis of
sternocleidomastoidsternocleidomastoid
 Cranial Nerve XIICranial Nerve XII
 Function: tongue movementsFunction: tongue movements
of speech, foodof speech, food
manipulation, and swallowingmanipulation, and swallowing
 Clinical test: tongue functionClinical test: tongue function
 Effects of damage: difficultyEffects of damage: difficulty
in speech and swallowing;in speech and swallowing;
atrophy of tongue; inability toatrophy of tongue; inability to
stick out (protrude) tonguestick out (protrude) tongue

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Brain and cranial nerves

  • 1. Brain and CranialBrain and Cranial NervesNerves
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  • 3. TerminologyTerminology  HemispheresHemispheres  Gyrus (Gyri)Gyrus (Gyri)  Sulcus (Sulci)Sulcus (Sulci)  Longitudinal FissureLongitudinal Fissure  VentriclesVentricles – CSFCSF
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  • 6. Anatomy of the BrainAnatomy of the Brain  CerebrumCerebrum  CerebellumCerebellum  DiencephalonDiencephalon – ThalamusThalamus – HyothalamusHyothalamus  Brain StemBrain Stem – MidbrainMidbrain – PonsPons – MedullaMedulla oblongataoblongata
  • 7. CerebrumCerebrum  AnatomyAnatomy – Frontal lobeFrontal lobe – Parietal lobeParietal lobe – Occipital lobeOccipital lobe – Precentral gyrusPrecentral gyrus – Postcentral gyrusPostcentral gyrus  FunctionsFunctions – Sensory cortexSensory cortex – Motor cortexMotor cortex – EmotionEmotion – IntellectualIntellectual processesprocesses – AuditoryAuditory – VisualVisual – SpeechSpeech
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  • 11. CerebellumCerebellum  AnatomyAnatomy – HemispheresHemispheres  FunctionsFunctions – Compares intendedCompares intended movement withmovement with what is actuallywhat is actually happeninghappening – Smooth,Smooth, coordinatedcoordinated movementsmovements – Posture/balancePosture/balance
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  • 13. Brain StemBrain Stem  AnatomyAnatomy – Medulla oblongataMedulla oblongata – PonsPons – MidbrainMidbrain  FunctionsFunctions – MedullaMedulla  Relays motor andRelays motor and sensory informationsensory information  Regulates heartbeat,Regulates heartbeat, breathing and bloodbreathing and blood vessel dilationvessel dilation – PonsPons  Control breathingControl breathing
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  • 19. Protective CoveringsProtective Coverings (Meninges)(Meninges)  Dura materDura mater Dense connective tissueDense connective tissue  ArachnoidArachnoid Nonvascular connective tissueNonvascular connective tissue  Pia materPia mater Highly vascularHighly vascular Covers surface of the brain and spinal cord andCovers surface of the brain and spinal cord and invaginates along cortical surface to forminvaginates along cortical surface to form perivascular spacesperivascular spaces
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  • 22. Cerebral Spinal FluidCerebral Spinal Fluid  Formed in the choroid plexusFormed in the choroid plexus  Reabsorbed into saggittal sinus byReabsorbed into saggittal sinus by arachnoid villiarachnoid villi  Protects brain against concussiveProtects brain against concussive traumatrauma  removes waste productsremoves waste products
  • 24. Cranial NervesCranial Nerves  I:I: OlfactoryOlfactory  II:II: OpticOptic  III:III: OculomotorOculomotor  IV:IV: TrochlearTrochlear  V:V: TrigeminalTrigeminal  VI:VI: AbducensAbducens  VII: FacialVII: Facial  VIII:VestibulocochlearVIII:Vestibulocochlear – AcousticAcoustic  IX:IX: GlossopharyngealGlossopharyngeal  X:X: VagusVagus  XI:XI: AccessoryAccessory  XII: HypoglossalXII: Hypoglossal http://www.gwc.maricopa.edu/class/bio201/cn/cranial.htm
  • 25. MnemonicMnemonic  OnOn  OldOld  Olympus’Olympus’  TowerTower  TopTop  AA  FinFin  AndAnd  GermanGerman  ViewedViewed  AA  HopHop
  • 26. MNEMONICMNEMONIC  OLFACTORYOLFACTORY  OPTICOPTIC  OCULOMOTOROCULOMOTOR  TROCHLEARTROCHLEAR  TRIGEMINALTRIGEMINAL  ABDUCENSABDUCENS  FACIALFACIAL  VESTIBULOCOCHLEVESTIBULOCOCHLE ARAR  GLOSSOPHARYNGEGLOSSOPHARYNGE ALAL  VAGUSVAGUS  ACCESSORYACCESSORY   OHOH  ONCEONCE  ONEONE  TAKESTAKES  THETHE  ANATOMYANATOMY  FINALFINAL  VERYVERY  GOODGOOD  VACATIONVACATION  A-HEADA-HEAD
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  • 28. CN I: OLFACTORYCN I: OLFACTORY  Cranial nerve ICranial nerve I  Function:Function: – smellsmell  Clinical test forClinical test for damage:damage: – determine whetherdetermine whether a person can smella person can smell something aromaticsomething aromatic
  • 29. CN II: OPTICCN II: OPTIC  Cranial nerve IICranial nerve II  Function:Function: – visionvision  Clinical test forClinical test for damage:damage: – tests peripheral visiontests peripheral vision and visual acuityand visual acuity  Effects of damage:Effects of damage: – blindness in part or all ofblindness in part or all of the visual fieldthe visual field
  • 30. CNIII: OCULOMOTORCNIII: OCULOMOTOR  Cranial nerve IIICranial nerve III  Function:Function: – eye movements, opening ofeye movements, opening of eyelid, constriction of pupil,eyelid, constriction of pupil, focusing, proprioceptionfocusing, proprioception  Clinical tests for injury:Clinical tests for injury: – differences in pupil size;differences in pupil size; pupillary response to light; eyepupillary response to light; eye trackingtracking  Effects of damageEffects of damage – dropping eyelid, dilated pupil,dropping eyelid, dilated pupil, double visiondouble vision
  • 31. CNIV: TROCHLEARCNIV: TROCHLEAR  Cranial nerve IVCranial nerve IV  Function: eye movementsFunction: eye movements and proprioceptionand proprioception  Clinical test for injury: abilityClinical test for injury: ability to rotate eye inferolaterallyto rotate eye inferolaterally  Effects of damage – doubleEffects of damage – double vision, patient tilts headvision, patient tilts head toward affected sidetoward affected side
  • 32. CN V: TRIGEMINALCN V: TRIGEMINAL  Cranial nerve VCranial nerve V  Function: sensory nerve of theFunction: sensory nerve of the faceface  Clinical test for injury:Clinical test for injury: – corneal reflex; sense ofcorneal reflex; sense of touch, pain, and temperature;touch, pain, and temperature; clench teeth; move mandibleclench teeth; move mandible side to sideside to side  Effects of damage:Effects of damage: – loss of sensation andloss of sensation and impaired chewingimpaired chewing
  • 33. CN VI: ABDUCENS ANDCN VI: ABDUCENS AND CN VII: FACIALCN VII: FACIAL  Cranial Nerve VICranial Nerve VI  Function: EyeFunction: Eye movementsmovements  Clinical test: lateral eyeClinical test: lateral eye movementmovement  Effects of damage:Effects of damage: inability to rotate eyeinability to rotate eye laterally; at rest – eyelaterally; at rest – eye rotates mediallyrotates medially because of action ofbecause of action of antagonistic musclesantagonistic muscles  Cranial Nerve VIICranial Nerve VII  Function: facialFunction: facial expression; sense ofexpression; sense of tastetaste  Clinical test: motorClinical test: motor functions – close eyes,functions – close eyes, smile, whistle, frown,smile, whistle, frown, raise eyebrows; tasteraise eyebrows; taste  Effects of damage:Effects of damage: inability to control facialinability to control facial muscles; distortedmuscles; distorted sense of tastesense of taste
  • 34. CN VIII:CN VIII: VESTIBULOCOCHLEARVESTIBULOCOCHLEAR  Cranial Nerve VIIICranial Nerve VIII  Function: hearing and equilibriumFunction: hearing and equilibrium  Clinical tests: test hearing, balance,Clinical tests: test hearing, balance, and ability to walk a straight lineand ability to walk a straight line  Effects of damage: deafness,Effects of damage: deafness, dizziness, nausea, loss of balance,dizziness, nausea, loss of balance, and nystagmusand nystagmus
  • 35. CN IX:CN IX: GLOSSOPHARANGEALGLOSSOPHARANGEAL AND CN X: VAGUSAND CN X: VAGUS Cranial Nerve IXCranial Nerve IX  Function: swallowing,Function: swallowing, salivation, gagging; touch,salivation, gagging; touch, pressure, taste, and painpressure, taste, and pain sensations from tongue,sensations from tongue, pharynx, and outer earpharynx, and outer ear  Clinical tests: gag reflex,Clinical tests: gag reflex, swallowing, and coughingswallowing, and coughing  Effects of damage: difficultyEffects of damage: difficulty swallowingswallowing  Cranial Nerve XCranial Nerve X  Function: swallowing; taste;Function: swallowing; taste; speech; respiratory, CV, andspeech; respiratory, CV, and GI regulation; sensations ofGI regulation; sensations of hunger, fullness, andhunger, fullness, and intestinal discomfortintestinal discomfort  Clinical tests: test withClinical tests: test with cranial nerve IXcranial nerve IX  Effects of damage:Effects of damage: hoarseness or loss of voice;hoarseness or loss of voice; impaired swallowing and GIimpaired swallowing and GI motilitymotility
  • 36. CN XI: ACCESSORYCN XI: ACCESSORY ANDAND CN XII: HYPOGLOSSALCN XII: HYPOGLOSSAL Cranial Nerve XICranial Nerve XI  Function: swallowing; head,Function: swallowing; head, neck, and shoulderneck, and shoulder movementsmovements  Clinical tests: rotate headClinical tests: rotate head and shrug shoulders againstand shrug shoulders against resistanceresistance  Effects of damage: impairedEffects of damage: impaired movement of head, neck,movement of head, neck, and shoulders; paralysis ofand shoulders; paralysis of sternocleidomastoidsternocleidomastoid  Cranial Nerve XIICranial Nerve XII  Function: tongue movementsFunction: tongue movements of speech, foodof speech, food manipulation, and swallowingmanipulation, and swallowing  Clinical test: tongue functionClinical test: tongue function  Effects of damage: difficultyEffects of damage: difficulty in speech and swallowing;in speech and swallowing; atrophy of tongue; inability toatrophy of tongue; inability to stick out (protrude) tonguestick out (protrude) tongue

Editor's Notes

  1. Largest of the cranial nerves Blinking in response to light touch to the eyeball
  2. Can be fatal if vagus nerve is damaged – 2 routes
  3. Paralysis will cause head to turn toward injured side