SlideShare a Scribd company logo
1 of 31
Cibernetica, modelli computazionali e tecnologie
                        informatiche
       per lo studio dei processi di cognizione sociale

              Nature, Nurture and Future
                  8 Dicembre 2009


                   Eye tracking & Vision Applications Lab (EVA Lab) Department of
                          Neurological Neurosurgical and Behavioral Science
12/01/2013                             University of Siena, Italy
                                                                                    1
Overview
•   Cibernetica
•   Knowledge Engineering
•   Biomedical Engineering
•   Neuronal Machine




               Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013     Neurological Neurosurgical and Behavioral Science University of   2
                                         Siena, Italy
Cibernetica
 La cibernetica è la scienza che studia i fenomeni
      di autoregolazione (controlli automatici e
    controlli adattativi) e comunicazione (teoria
     dell'informazione - IT), sia negli organismi
         naturali quanto nei sistemi artificiali.

                                                                                 Norbert Wiener



               Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013     Neurological Neurosurgical and Behavioral Science University of                3
                                         Siena, Italy
Knowledge Engineering
                                                       Example
 Data                                                  … --- …
 Information                                           SOS
 Knowledge                                             emergency alert

                              • Biomedical System
             Data             • Telecomunication System
                              • Storage System


                              • Storage System
  Information                 • Data Mining & Search Engine
                              • Image , Signal Processing




   Knowledge                  • Knowledge Based Storage
                              • Automatic, Adaptive, Complex Control


                    Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013          Neurological Neurosurgical and Behavioral Science University of   4
                                              Siena, Italy
Ingegneria Biomedica (una volta Bio
                Ingegneria)
                                                             Estrarre dati
                        Costruire
                                                               (sistemi
                         sistemi
                                                              biomedici)




                                                                           Produrre
             Emulare                                                     Informazione
              sistemi                                                      (Signal &
             naturali                                                        Image
                                                                          Processing)


                                         Modellare
                                          sistemi
                                          naturali


                  Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013        Neurological Neurosurgical and Behavioral Science University of       5
                                            Siena, Italy
Biomedical System




              Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013    Neurological Neurosurgical and Behavioral Science University of   6
                                        Siena, Italy
fMRI




             Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013   Neurological Neurosurgical and Behavioral Science University of   7
                                       Siena, Italy
Eye Tracking
EOG                                            Pupil Tracking




             Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013   Neurological Neurosurgical and Behavioral Science University of   8
                                       Siena, Italy
EEG & Evocated Potential
Signal Decomposition                                EEG




                  Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013        Neurological Neurosurgical and Behavioral Science University of   9
                                            Siena, Italy
Active System
tDCS                                           TMS




             Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013   Neurological Neurosurgical and Behavioral Science University of   10
                                       Siena, Italy
IT & LIFE

              Data 2 Information




             Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013   Neurological Neurosurgical and Behavioral Science University of   11
                                       Siena, Italy
Search Engine – Patent DB




                  Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013        Neurological Neurosurgical and Behavioral Science University of   12
                                            Siena, Italy
Tele Riabilitazione : Eracle Project

In loco rehabilitation

     Tele-rehabilitation

             Remote help desk

               Social Area


                   Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013         Neurological Neurosurgical and Behavioral Science University of   13
                                             Siena, Italy
Decision Making - NeuroEconomic

• Game Theory
• The subject was asked
  to choose between two
  sign according to
  previous chooses
    – Overconfident
    – Bayesian



                                                           [Innocenti & Rufa 2010]

1/12/2013         EVA – EYE TRACKING - STIMULUS INTEGRATED SEMI AUTOMATIC
                                       CASE BASE SYSTEM
                                                                                     14
Knowlede Management nelle
              Scienze della Vita




               Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013     Neurological Neurosurgical and Behavioral Science University of   15
                                         Siena, Italy
Algoritmi per la Diagnosi
                                                        • Ipertensione
                                                          endocranica idiopatica




[Tornese 2007]




                      Eye tracking & Vision Applications Lab (EVA Lab) Department of
    12/01/2013        Neurological Neurosurgical and Behavioral Science University of   16
                                                Siena, Italy
Biomedical System
• “More 60% of our Barin
  works on vision …”:

     – Image Processing
     – Attention
     – Working memory
     – Memory
     – Visual-Spatial
       exploration
     – Eye Movement
     – Intention                                        The focus of attention is jointly determined by stimulus salience and
     – Decision                                         top-down control signals. IOR is implemented by a mechanism that
                                                        reduces the salience of stimuli at recently explored spatial locations.



                    Eye tracking & Vision Applications Lab (EVA Lab) Department of
 12/01/2013         Neurological Neurosurgical and Behavioral Science University of                                  17
                                              Siena, Italy
EVA – EYE TRACKING - STIMULUS INTEGRATED
      SEMI AUTOMATIC CASE BASESYSTEM
                         • Test the cognitive
                           system by multi-
                           stimulus
                         • Diagnosis by Case
                           Base




              Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013    Neurological Neurosurgical and Behavioral Science University of   18
                                        Siena, Italy
EVA – EYE TRACKING - STIMULUS INTEGRATED SEMI
              AUTOMATIC CASE BASESYSTEM
                                                       Case Base                                   University
                                                                                                    of Siena
                                                                                                     Patent

                                            Analysis
                                          (Indicators)

                                                                                             Diagnosis
Vision Cognitive
      Task
                                                                                           Rehabilitation



                   STIMULUS INTEGRATED SEMI AUTOMATIC CASE
                                 BASE SYSTEM

                         Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013               Neurological Neurosurgical and Behavioral Science University of                        19
                                                   Siena, Italy
Mean Sequence
• Diagnosis SCA2
• Vp=Vmax (1 – exp(A/C))




  [Leigh 2004]




                 Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013       Neurological Neurosurgical and Behavioral Science University of   20
                                           Siena, Italy
Nauronal Machine

              Model of Brain and ….




               Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013     Neurological Neurosurgical and Behavioral Science University of   21
                                         Siena, Italy
Working Memory & Visual Search
• Working memory :
     – is a theoretical construct
       that refers to the
       structures and processes
       used for temporarily
       storing and manipulating
       information.
• Visual Search
     – memory maintains the
       information in order to
       allow past experience to
       guide future behaviors
                      Eye tracking & Vision Applications Lab (EVA Lab) Department of
 12/01/2013           Neurological Neurosurgical and Behavioral Science University of   22
                                                Siena, Italy
Early Model of saccade System




        Neural network


                         Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013               Neurological Neurosurgical and Behavioral Science University of   23
                                                   Siena, Italy
Cerebellum as adaptive control




             [Ito 2008]




                                                                     [2007 T. Yamazaki]


                 Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013       Neurological Neurosurgical and Behavioral Science University of          24
                                           Siena, Italy
A real-time spiking cerebellum model
          for learning robot control
[Carrillo 2008]




                  Eye tracking & Vision Applications Lab (EVA Lab) Department of
  12/01/2013      Neurological Neurosurgical and Behavioral Science University of   25
                                            Siena, Italy
Visual Search
                                            Planning fixations




                                                                               Priority map   Frontal area




                                                                     Internal intention

                          [Itti 2000]




             Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013   Neurological Neurosurgical and Behavioral Science University of                            26
                                       Siena, Italy
Eye Movements & Attention
• Eye movements
    – Sequences of fixation and
      saccade
    – The sequences of saccade-
      and-fixation enable humans
      to receive a continuous flow
                                                                      Peripheral attention
      of information from the                                         Saccadic eye movements
      world.
                                                                            Overlapped region
• Attention
    – Attention is the process of
      selecting a few relevant
      perceptive stimuli by filtering
      of negligible aspect of the
      environment
                        Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013              Neurological Neurosurgical and Behavioral Science University of         27
                                                  Siena, Italy
Break Away from Fixations




                  Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013        Neurological Neurosurgical and Behavioral Science University of   28
                                            Siena, Italy
Break Away from Fixations Model



[Veneri 2010]

                              100
                                                                                                 100

                              200
                                                                                                 200

                              300
                                                                                                 300

                              400
                                                                                                 400

                              500
                                                                                                 500

                              600
                                                                                                 600

                              700
                                                                                                 700

                                    100   200   300   400   500   600   700   800   900   1000
                                                                                                       100   200   300   400   500   600   700   800   900   1000




                Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013      Neurological Neurosurgical and Behavioral Science University of                                                                                29
                                          Siena, Italy
Decisione Making
• Decision making:
    – can be regarded as
      an outcome of
      mental processes
      (cognitive process)
      leading to the
      selection of a course
                                                       Basic connectivity framework. Dotted arrows represent external
      of action among                                  inputs to the model. Abbreviations: 5-HT, dorsal raphe serotonergic
                                                       neurons; ACC, anterior cingulate cortex; AMYG, amygdala; DA,

      several alternatives.                            midbrain dopaminergic neurons; DLPFC, dorsolateral prefrontal
                                                       cortex; OFC, orbitofrontal cortex; VS, ventral striatum.




                  Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013        Neurological Neurosurgical and Behavioral Science University of                                    30
                                            Siena, Italy
References
•   Carrillo R, Ros E, Boucheny C, Coenen O. A real-time spiking           •      1975 – Engel - Visual cospicuity, visual search and fixation
    cerebellum model for learning robot control. Biosystems.                      tendencies of the eye – Vision
    2008;94(1-2):18-27. Available at:                                      •      1976 – Banks et al – Configurational effects in visual information
    http://linkinghub.elsevier.com/retrieve/pii/S0303264708001226.                processing. Perception & Psycophysics
•   Ito M. Control of mental activities by internal models in the          •      1993- Fischer, B., Biscaldi, M., and Otto. Saccadic eye movements
    cerebellum. Nature. (Box 1).                                                  of dyslexic adults. Neuropsychologia, Vol. 31, No 9, pp. 887-906.
•   Karl E. Misulis, Toufic Fakhoury (2001), Spehlmann's Evoked            •      Zhaoping Li 2002, A Saliency Map in Primary Visual Cortex (2002),
    Potential Primer, Butterworth-heinemann                                       Trends in neuroscience
                                                                           •      W. Wolwer 2003 – Trait Characteristic id Impaired Visuomotor
                                                                                  Integration during Trail-Making Test B Performance in
                                                                                  Schozophrenia – Neuropsycobiology
                                                                           •      2004 E.Davis – Visual search attention – Spatial Vision
                                                                           •      2004 R.Leigh – Using saccades as a research tool in clinical
                                                                                  neurosciences – Brain
                                                                           •      2005 B. Machner – cerebellar infarction affects visual search -
                                                                                  Neuroreport
                                                                           •      2006 – Administration and interpretation of the Trail Making Test –
                                                                                  Nature Protocols
                                                                           •      2006 – H. Ojanpaa - Visual search and eye movements in patients
                                                                                  with chronic solvent-induced toxic enecelophaty – NeuroToxicology
                                                                           •      2007 – T. Yamazaki,Shigeru Tanaka - The cerebellum as a liquid
                                                                                  state machine – Neural Network
                                                                           •      2008 G. Jacobson, et Al.- A model of the olivo-cerebellar system as a
                                                                                  temporal pattern generator
                                                                           •      2008 M. Ito - Cerebellar circuitry as a neuronal machine – Nat
                                                                                  neuroscience


                                         Eye tracking & Vision Applications Lab (EVA Lab) Department of
12/01/2013                               Neurological Neurosurgical and Behavioral Science University of                                           31
                                                                   Siena, Italy

More Related Content

Similar to Cibernetica, modelli computazionali e tecnologie informatiche

Enhancement of Multi-Modal Biometric Authentication Based on IRIS and Brain N...
Enhancement of Multi-Modal Biometric Authentication Based on IRIS and Brain N...Enhancement of Multi-Modal Biometric Authentication Based on IRIS and Brain N...
Enhancement of Multi-Modal Biometric Authentication Based on IRIS and Brain N...CSCJournals
 
Biomedical Images.ppt
Biomedical Images.pptBiomedical Images.ppt
Biomedical Images.pptbreenaawan
 
Evaluating Human Visual Search Performance by Monte Carlo methods and Heurist...
Evaluating Human Visual Search Performance by Monte Carlo methods and Heurist...Evaluating Human Visual Search Performance by Monte Carlo methods and Heurist...
Evaluating Human Visual Search Performance by Monte Carlo methods and Heurist...Giacomo Veneri
 
Voice based Application as Medicine Spotter for Visually Impaired
Voice based Application as Medicine Spotter for Visually ImpairedVoice based Application as Medicine Spotter for Visually Impaired
Voice based Application as Medicine Spotter for Visually ImpairedIRJET Journal
 
Giiacomo Veneri PHD Dissertation
Giiacomo Veneri PHD Dissertation Giiacomo Veneri PHD Dissertation
Giiacomo Veneri PHD Dissertation Giacomo Veneri
 
Giacomo Veneri 2012 phd dissertation
Giacomo Veneri 2012 phd dissertationGiacomo Veneri 2012 phd dissertation
Giacomo Veneri 2012 phd dissertationGiacomo Veneri
 
Eye Blink and Hand Gesture detection For Aid of Paralyzed Patients
Eye Blink and Hand Gesture detection For Aid of Paralyzed PatientsEye Blink and Hand Gesture detection For Aid of Paralyzed Patients
Eye Blink and Hand Gesture detection For Aid of Paralyzed PatientsIRJET Journal
 
An efficient system for real time fatigue detection
An efficient system for real time fatigue detectionAn efficient system for real time fatigue detection
An efficient system for real time fatigue detectionAlexander Decker
 
A review of consumer brain computer interface devices
A review of consumer brain computer interface devicesA review of consumer brain computer interface devices
A review of consumer brain computer interface devicesRex Yuan
 
A comparison of multiple wavelet algorithms for iris recognition 2
A comparison of multiple wavelet algorithms for iris recognition 2A comparison of multiple wavelet algorithms for iris recognition 2
A comparison of multiple wavelet algorithms for iris recognition 2IAEME Publication
 
A Document on Artificial Passenger
A Document on Artificial PassengerA Document on Artificial Passenger
A Document on Artificial PassengerMohammed Iqbal
 
Meniscus, the Eye Diagnostic Integrated Facility
Meniscus, the Eye Diagnostic Integrated FacilityMeniscus, the Eye Diagnostic Integrated Facility
Meniscus, the Eye Diagnostic Integrated FacilityKumara Sadana Putra
 
A03640106
A03640106A03640106
A03640106theijes
 

Similar to Cibernetica, modelli computazionali e tecnologie informatiche (20)

Retinal Recognition
Retinal RecognitionRetinal Recognition
Retinal Recognition
 
Enhancement of Multi-Modal Biometric Authentication Based on IRIS and Brain N...
Enhancement of Multi-Modal Biometric Authentication Based on IRIS and Brain N...Enhancement of Multi-Modal Biometric Authentication Based on IRIS and Brain N...
Enhancement of Multi-Modal Biometric Authentication Based on IRIS and Brain N...
 
Biomedical Images.ppt
Biomedical Images.pptBiomedical Images.ppt
Biomedical Images.ppt
 
Evaluating Human Visual Search Performance by Monte Carlo methods and Heurist...
Evaluating Human Visual Search Performance by Monte Carlo methods and Heurist...Evaluating Human Visual Search Performance by Monte Carlo methods and Heurist...
Evaluating Human Visual Search Performance by Monte Carlo methods and Heurist...
 
Voice based Application as Medicine Spotter for Visually Impaired
Voice based Application as Medicine Spotter for Visually ImpairedVoice based Application as Medicine Spotter for Visually Impaired
Voice based Application as Medicine Spotter for Visually Impaired
 
Project oculus
Project oculus Project oculus
Project oculus
 
Giiacomo Veneri PHD Dissertation
Giiacomo Veneri PHD Dissertation Giiacomo Veneri PHD Dissertation
Giiacomo Veneri PHD Dissertation
 
Giacomo Veneri 2012 phd dissertation
Giacomo Veneri 2012 phd dissertationGiacomo Veneri 2012 phd dissertation
Giacomo Veneri 2012 phd dissertation
 
retina
retinaretina
retina
 
Eye Blink and Hand Gesture detection For Aid of Paralyzed Patients
Eye Blink and Hand Gesture detection For Aid of Paralyzed PatientsEye Blink and Hand Gesture detection For Aid of Paralyzed Patients
Eye Blink and Hand Gesture detection For Aid of Paralyzed Patients
 
An efficient system for real time fatigue detection
An efficient system for real time fatigue detectionAn efficient system for real time fatigue detection
An efficient system for real time fatigue detection
 
A review of consumer brain computer interface devices
A review of consumer brain computer interface devicesA review of consumer brain computer interface devices
A review of consumer brain computer interface devices
 
643 648
643 648643 648
643 648
 
V4 n2 139
V4 n2 139V4 n2 139
V4 n2 139
 
K0966468
K0966468K0966468
K0966468
 
A comparison of multiple wavelet algorithms for iris recognition 2
A comparison of multiple wavelet algorithms for iris recognition 2A comparison of multiple wavelet algorithms for iris recognition 2
A comparison of multiple wavelet algorithms for iris recognition 2
 
A Document on Artificial Passenger
A Document on Artificial PassengerA Document on Artificial Passenger
A Document on Artificial Passenger
 
L_3011_62.+1908
L_3011_62.+1908L_3011_62.+1908
L_3011_62.+1908
 
Meniscus, the Eye Diagnostic Integrated Facility
Meniscus, the Eye Diagnostic Integrated FacilityMeniscus, the Eye Diagnostic Integrated Facility
Meniscus, the Eye Diagnostic Integrated Facility
 
A03640106
A03640106A03640106
A03640106
 

More from Giacomo Veneri

Giacomo Veneri Thesis 1999 University of Siena
Giacomo Veneri Thesis 1999 University of SienaGiacomo Veneri Thesis 1999 University of Siena
Giacomo Veneri Thesis 1999 University of SienaGiacomo Veneri
 
Industrial IoT - build your industry 4.0 @techitaly
Industrial IoT - build your industry 4.0 @techitalyIndustrial IoT - build your industry 4.0 @techitaly
Industrial IoT - build your industry 4.0 @techitalyGiacomo Veneri
 
Preparing Java 7 Certifications
Preparing Java 7 CertificationsPreparing Java 7 Certifications
Preparing Java 7 CertificationsGiacomo Veneri
 
Pattern recognition on human vision
Pattern recognition on human visionPattern recognition on human vision
Pattern recognition on human visionGiacomo Veneri
 
From Java 6 to Java 7 reference
From Java 6 to Java 7 referenceFrom Java 6 to Java 7 reference
From Java 6 to Java 7 referenceGiacomo Veneri
 
Bayesain Hypothesis of Selective Attention - Raw 2011 poster
Bayesain Hypothesis of Selective Attention - Raw 2011 posterBayesain Hypothesis of Selective Attention - Raw 2011 poster
Bayesain Hypothesis of Selective Attention - Raw 2011 posterGiacomo Veneri
 
Raw 2009 -THE ROLE OF LATEST FIXATIONS ON ONGOING VISUAL SEARCH A MODEL TO E...
Raw 2009 -THE ROLE OF LATEST FIXATIONS ON ONGOING VISUAL SEARCH  A MODEL TO E...Raw 2009 -THE ROLE OF LATEST FIXATIONS ON ONGOING VISUAL SEARCH  A MODEL TO E...
Raw 2009 -THE ROLE OF LATEST FIXATIONS ON ONGOING VISUAL SEARCH A MODEL TO E...Giacomo Veneri
 
Eracle project poster_session_efns
Eracle project poster_session_efnsEracle project poster_session_efns
Eracle project poster_session_efnsGiacomo Veneri
 
THE ROLE OF LATEST FIXATIONS ON ONGOING VISUAL SEARCH
THE ROLE OF LATEST FIXATIONS ON ONGOING VISUAL SEARCH THE ROLE OF LATEST FIXATIONS ON ONGOING VISUAL SEARCH
THE ROLE OF LATEST FIXATIONS ON ONGOING VISUAL SEARCH Giacomo Veneri
 

More from Giacomo Veneri (13)

Giacomo Veneri Thesis 1999 University of Siena
Giacomo Veneri Thesis 1999 University of SienaGiacomo Veneri Thesis 1999 University of Siena
Giacomo Veneri Thesis 1999 University of Siena
 
Industrial IoT - build your industry 4.0 @techitaly
Industrial IoT - build your industry 4.0 @techitalyIndustrial IoT - build your industry 4.0 @techitaly
Industrial IoT - build your industry 4.0 @techitaly
 
Preparing Java 7 Certifications
Preparing Java 7 CertificationsPreparing Java 7 Certifications
Preparing Java 7 Certifications
 
Pattern recognition on human vision
Pattern recognition on human visionPattern recognition on human vision
Pattern recognition on human vision
 
Advanced java
Advanced javaAdvanced java
Advanced java
 
From Java 6 to Java 7 reference
From Java 6 to Java 7 referenceFrom Java 6 to Java 7 reference
From Java 6 to Java 7 reference
 
Bayesain Hypothesis of Selective Attention - Raw 2011 poster
Bayesain Hypothesis of Selective Attention - Raw 2011 posterBayesain Hypothesis of Selective Attention - Raw 2011 poster
Bayesain Hypothesis of Selective Attention - Raw 2011 poster
 
Raw 2009 -THE ROLE OF LATEST FIXATIONS ON ONGOING VISUAL SEARCH A MODEL TO E...
Raw 2009 -THE ROLE OF LATEST FIXATIONS ON ONGOING VISUAL SEARCH  A MODEL TO E...Raw 2009 -THE ROLE OF LATEST FIXATIONS ON ONGOING VISUAL SEARCH  A MODEL TO E...
Raw 2009 -THE ROLE OF LATEST FIXATIONS ON ONGOING VISUAL SEARCH A MODEL TO E...
 
Eracle project poster_session_efns
Eracle project poster_session_efnsEracle project poster_session_efns
Eracle project poster_session_efns
 
Dal web 2 al web 3
Dal web 2 al web 3Dal web 2 al web 3
Dal web 2 al web 3
 
Il web 2.0
Il web 2.0Il web 2.0
Il web 2.0
 
Giacomo Veneri Thesis
Giacomo Veneri ThesisGiacomo Veneri Thesis
Giacomo Veneri Thesis
 
THE ROLE OF LATEST FIXATIONS ON ONGOING VISUAL SEARCH
THE ROLE OF LATEST FIXATIONS ON ONGOING VISUAL SEARCH THE ROLE OF LATEST FIXATIONS ON ONGOING VISUAL SEARCH
THE ROLE OF LATEST FIXATIONS ON ONGOING VISUAL SEARCH
 

Cibernetica, modelli computazionali e tecnologie informatiche

  • 1. Cibernetica, modelli computazionali e tecnologie informatiche per lo studio dei processi di cognizione sociale Nature, Nurture and Future 8 Dicembre 2009 Eye tracking & Vision Applications Lab (EVA Lab) Department of Neurological Neurosurgical and Behavioral Science 12/01/2013 University of Siena, Italy 1
  • 2. Overview • Cibernetica • Knowledge Engineering • Biomedical Engineering • Neuronal Machine Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 2 Siena, Italy
  • 3. Cibernetica La cibernetica è la scienza che studia i fenomeni di autoregolazione (controlli automatici e controlli adattativi) e comunicazione (teoria dell'informazione - IT), sia negli organismi naturali quanto nei sistemi artificiali. Norbert Wiener Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 3 Siena, Italy
  • 4. Knowledge Engineering Example Data … --- … Information SOS Knowledge emergency alert • Biomedical System Data • Telecomunication System • Storage System • Storage System Information • Data Mining & Search Engine • Image , Signal Processing Knowledge • Knowledge Based Storage • Automatic, Adaptive, Complex Control Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 4 Siena, Italy
  • 5. Ingegneria Biomedica (una volta Bio Ingegneria) Estrarre dati Costruire (sistemi sistemi biomedici) Produrre Emulare Informazione sistemi (Signal & naturali Image Processing) Modellare sistemi naturali Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 5 Siena, Italy
  • 6. Biomedical System Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 6 Siena, Italy
  • 7. fMRI Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 7 Siena, Italy
  • 8. Eye Tracking EOG Pupil Tracking Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 8 Siena, Italy
  • 9. EEG & Evocated Potential Signal Decomposition EEG Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 9 Siena, Italy
  • 10. Active System tDCS TMS Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 10 Siena, Italy
  • 11. IT & LIFE Data 2 Information Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 11 Siena, Italy
  • 12. Search Engine – Patent DB Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 12 Siena, Italy
  • 13. Tele Riabilitazione : Eracle Project In loco rehabilitation Tele-rehabilitation Remote help desk Social Area Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 13 Siena, Italy
  • 14. Decision Making - NeuroEconomic • Game Theory • The subject was asked to choose between two sign according to previous chooses – Overconfident – Bayesian [Innocenti & Rufa 2010] 1/12/2013 EVA – EYE TRACKING - STIMULUS INTEGRATED SEMI AUTOMATIC CASE BASE SYSTEM 14
  • 15. Knowlede Management nelle Scienze della Vita Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 15 Siena, Italy
  • 16. Algoritmi per la Diagnosi • Ipertensione endocranica idiopatica [Tornese 2007] Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 16 Siena, Italy
  • 17. Biomedical System • “More 60% of our Barin works on vision …”: – Image Processing – Attention – Working memory – Memory – Visual-Spatial exploration – Eye Movement – Intention The focus of attention is jointly determined by stimulus salience and – Decision top-down control signals. IOR is implemented by a mechanism that reduces the salience of stimuli at recently explored spatial locations. Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 17 Siena, Italy
  • 18. EVA – EYE TRACKING - STIMULUS INTEGRATED SEMI AUTOMATIC CASE BASESYSTEM • Test the cognitive system by multi- stimulus • Diagnosis by Case Base Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 18 Siena, Italy
  • 19. EVA – EYE TRACKING - STIMULUS INTEGRATED SEMI AUTOMATIC CASE BASESYSTEM Case Base University of Siena Patent Analysis (Indicators) Diagnosis Vision Cognitive Task Rehabilitation STIMULUS INTEGRATED SEMI AUTOMATIC CASE BASE SYSTEM Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 19 Siena, Italy
  • 20. Mean Sequence • Diagnosis SCA2 • Vp=Vmax (1 – exp(A/C)) [Leigh 2004] Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 20 Siena, Italy
  • 21. Nauronal Machine Model of Brain and …. Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 21 Siena, Italy
  • 22. Working Memory & Visual Search • Working memory : – is a theoretical construct that refers to the structures and processes used for temporarily storing and manipulating information. • Visual Search – memory maintains the information in order to allow past experience to guide future behaviors Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 22 Siena, Italy
  • 23. Early Model of saccade System Neural network Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 23 Siena, Italy
  • 24. Cerebellum as adaptive control [Ito 2008] [2007 T. Yamazaki] Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 24 Siena, Italy
  • 25. A real-time spiking cerebellum model for learning robot control [Carrillo 2008] Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 25 Siena, Italy
  • 26. Visual Search Planning fixations Priority map Frontal area Internal intention [Itti 2000] Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 26 Siena, Italy
  • 27. Eye Movements & Attention • Eye movements – Sequences of fixation and saccade – The sequences of saccade- and-fixation enable humans to receive a continuous flow Peripheral attention of information from the Saccadic eye movements world. Overlapped region • Attention – Attention is the process of selecting a few relevant perceptive stimuli by filtering of negligible aspect of the environment Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 27 Siena, Italy
  • 28. Break Away from Fixations Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 28 Siena, Italy
  • 29. Break Away from Fixations Model [Veneri 2010] 100 100 200 200 300 300 400 400 500 500 600 600 700 700 100 200 300 400 500 600 700 800 900 1000 100 200 300 400 500 600 700 800 900 1000 Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 29 Siena, Italy
  • 30. Decisione Making • Decision making: – can be regarded as an outcome of mental processes (cognitive process) leading to the selection of a course Basic connectivity framework. Dotted arrows represent external of action among inputs to the model. Abbreviations: 5-HT, dorsal raphe serotonergic neurons; ACC, anterior cingulate cortex; AMYG, amygdala; DA, several alternatives. midbrain dopaminergic neurons; DLPFC, dorsolateral prefrontal cortex; OFC, orbitofrontal cortex; VS, ventral striatum. Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 30 Siena, Italy
  • 31. References • Carrillo R, Ros E, Boucheny C, Coenen O. A real-time spiking • 1975 – Engel - Visual cospicuity, visual search and fixation cerebellum model for learning robot control. Biosystems. tendencies of the eye – Vision 2008;94(1-2):18-27. Available at: • 1976 – Banks et al – Configurational effects in visual information http://linkinghub.elsevier.com/retrieve/pii/S0303264708001226. processing. Perception & Psycophysics • Ito M. Control of mental activities by internal models in the • 1993- Fischer, B., Biscaldi, M., and Otto. Saccadic eye movements cerebellum. Nature. (Box 1). of dyslexic adults. Neuropsychologia, Vol. 31, No 9, pp. 887-906. • Karl E. Misulis, Toufic Fakhoury (2001), Spehlmann's Evoked • Zhaoping Li 2002, A Saliency Map in Primary Visual Cortex (2002), Potential Primer, Butterworth-heinemann Trends in neuroscience • W. Wolwer 2003 – Trait Characteristic id Impaired Visuomotor Integration during Trail-Making Test B Performance in Schozophrenia – Neuropsycobiology • 2004 E.Davis – Visual search attention – Spatial Vision • 2004 R.Leigh – Using saccades as a research tool in clinical neurosciences – Brain • 2005 B. Machner – cerebellar infarction affects visual search - Neuroreport • 2006 – Administration and interpretation of the Trail Making Test – Nature Protocols • 2006 – H. Ojanpaa - Visual search and eye movements in patients with chronic solvent-induced toxic enecelophaty – NeuroToxicology • 2007 – T. Yamazaki,Shigeru Tanaka - The cerebellum as a liquid state machine – Neural Network • 2008 G. Jacobson, et Al.- A model of the olivo-cerebellar system as a temporal pattern generator • 2008 M. Ito - Cerebellar circuitry as a neuronal machine – Nat neuroscience Eye tracking & Vision Applications Lab (EVA Lab) Department of 12/01/2013 Neurological Neurosurgical and Behavioral Science University of 31 Siena, Italy