Fertility Road Magazine

HEALTH
AND SAFETY
How your 9-5 could be
affecting your fertility
ALL CHANGE
Why switching fertility
clinics could be the
best move you make
FERTILITY
JOURNEYS
Your chance for free
fertility treatment
with Klinnik Hausken
DRMARILYNGLENVILLE • BEHINDTHESCENES…WITHACONSULTANTANDROLOGIST • GLOBALSURROGACY:UPDATE
UK£3.95,US$10.99,CAN$10.99
ISSUE30JAN-FEB2016
PRINTEDINTHEUK
FertilityRoad
SUPPORTING YOU ON YOUR FERTILITY JOURNEY WWW.FERTILITYROAD.COM
FERTILITYFITMAKE 2016 YOUR HEALTHIEST YEAR YET
4 REASONSFOR FERTILITYOPTIMISM
IN 2016

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06 FertilityRoad WWW.FERTILITYROAD.COM
January/February2016Issue30
Welcome to the first issue of Fertility Road for 2016, and what a year this
could be!
Of course, it’s usual for optimism to dominate your thoughts at the start of a new year - there’s
a sense that anything is possible, and this wave of positivity provides the perfect conditions for
starting or extending a family.With that in mind, we look at four reasons for fertility optimism
in this issue, as well as presenting a host of other features which, we hope, will energise you for
your journey ahead.
We’ve got an update on our Fertility Journeys, pieces on fitness, clinics and the work/life
balance, plus we’ve been granted insider access to find out how one of the specialists at the
University College London Hospital operates at the front line of fertility science.
All that remains is to wish you every success for the year ahead.We have some exciting
developments on the way, all designed to inform and inspire, but we’re only as good and as
relevant as you, our readers, make us, so please continue to send in your feedback, thoughts,
stories and ideas – we love hearing from you.
The Fertility Road team
fertilityroad fertilityroadmag
Publisher
Tone Jarvis
tone@fertilityroad.com
Managing Editor
James Evans
editor@fertilityroad.com
Managing Director
PJ Mack
Art Editor
Richard Porter
Advertising
sales@fertilityroad.com
UK 020 7183 9882
US (323) 892-8486
Accounts Manager
Lynsey Jackman
lynsey@fertilityroad.com
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Published by
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FertilityRoadisnowavailableto
readacrossalltabletsandmobile
devicesfertilityroad.com/digital
Some of our writers
Lucy MillerA Level 3 fitness trainer and former competitive gymnast, Lucy is
Fitness Editor for Health & Fitness magazine and an expert in strength, health and
wellbeing. She has a huge wealth of experience in managing the fitness of children,
as well as their parents!
Liz Parry is a journalist and editor specialising in holistic health and wellbeing. She
has written for a number of national newspapers, magazines and websites including
The Guardian,The Ecologist, Psychologies, Natural Health and High 50.
Camilla Davies Camilla has a deep interest in fertility matters, particularly
when it comes to new and exciting advances in reproductive technology. She is
passionate about documenting the journey to parenthood, from pre-conception up
to the moment of birth and beyond.
Jessica Hepburn Jessica is author of memoir ThePursuitofMotherhood, which
documents her long and heartbreaking journey to have her own biological baby.Through
writing,her aim is to raise awareness of infertility,improve diagnosis and treatment,and help
women see that, whatever the result, their attempt to create a life can be life-enhancing.
Kate Brian A former Channel Four News journalist, Kate is the author of The
Complete Guide to IVF and Precious Babies. She’s the London representative for
Infertility Network UK and Editor of the Journal of Fertility Counselling. Kate’s
children were both IVF babies, and she specialises in writing about fertility.
Lucy Cuthew is an editor and author, specialising in children’s and young adult
fiction. She is the author of Horrible Love Story, a novel for teenagers, out this year. She
has written over 30 books for children. She is interested in the relationship between
words and emotions, and wrote her way through her own fertility journey, having had
twins through IVF.

FertilityRoad 07WWW.FERTILITYROAD.COM
Contents
17 FERTILITY FIT 2016
Time to make those positive lifestyle
changes for 2016 – let’s go!
25 FERTILITY JOURNEYS
We’re delighted to welcome our latest
Fertility Journeys partner, and our first
from Scandinavia, as Klinnik Hausken
open their doors offering free IVF
treatment to a Fertility Road couple.
35 ALL CHANGE
We explore the logic behind switching
fertility clinics, speaking to couples who
have had mixed experiences having
made a change.
42 FERTILITY HEALTH
AND SAFETY
We revisit the science that says
mismanaging your work/life balance
could be profoundly bad for your
chances of conceiving. So close that
Excel spreadsheet and read this!
48 FOUR REASONS FOR
FERTILITY OPTIMISM
In a world seemingly obsessed with
statistics, we’re putting forward four
very simple reasons why the benefit of
having optimism in your fertility is not
a theory, but a fact!
53 SURROGACY –
WHERE IS IT GOING?
An update on the global situation
surrounding surrogacy from guest
writer Sam Everingham.
58 A STORY TO TELL
Author Lucy Cuthew reveals the
inspiration and perspiration behind
creative writing for fertility, whilst
inviting others to put pen to paper.
62 BEHIND THE SCENES…
WITH A CONSULTANT
ANDROLOGIST
Fertility Road’s Kate Brian is granted
exclusive access to the University
College Hospital London to spend
a day with Consultant Andrologist
Asif Muneer.
17
35 50
FERTILITY
FIVER
LOUISE BROWN
EXCLUSIVE
The daughter of IVF on the
birth of her second child
YOUR
PRE-CONCEPTION
MAKEOVER
How to physically and
mentally fine-tune
your fertility aims
LOSS ADJUSTER
How Fertility Road
readers have overcome
the heartbreak of
failed pregnancies
FertilityRoad
THE WORLD’S NUMBER 1 FERTILITY MAGAZINE
YOUR JOURNEY TO PREGNANCY AND PARENTING WWW.FERTILITYROAD.COM
9BESPOKE
FERTILITY GUIDES
law, hypnotherapy,
books, holistic, web
and more
SACRAL MASSAGE • LETTER FROM THE HEART • WIN A FREE ONE-TO-ONE FERTILITY CONSULTATION
FERTILITY
FIVER
FORAWHY GETTING
PREGNANT NEEDN’T
COST THE EARTH
SEP-OCT2013
£3.95/€4.95
SUBSCRIBE
Takeout an annual subscription to
FertilityRoadfor just £5.99, a saving
of33%. For more information on this
offervisit
fertilityroad.com/digital
40
FIGHTING FIT?
Revealed: the myths
and the magic of
fertility and pregnancy
fitness regimes
CLOCK WATCHING
Dr. Jean Twenge on the
research that’s offering
new hope to millions
of couples
PICTURE THIS
How a brush with art
can help ease the pain
of infertility
FertilityRoad
THE WORLD’S NUMBER ONE FERTILITY MAGAZINE
YOUR JOURNEY TO PREGNANCY AND PARENTING WWW.FERTILITYROAD.COM
7BESPOKE
FERTILITYGUIDES
Science, social, web,
product reviews, holistic ,homecare and travel
INFERTILITY NETWORK UK • SURROGACY • FERTILITY RESOURCES GUIDE
ABATH,ABOOK,AMEAL,AMANTRA...READERSREVEAL
THETHINGSTHATKEEPTHEIRSPIRITSHIGH
NOV/DEC2013
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ULTIMATE
FERTILITYFINDS
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News, Views and Reviews
and
Helping Couples
to Conceive,
Naturally…
Female Fertility Support
Natural supplements to help with cycle regularity,
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Male Fertility Enhancement
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Ovulation Prediction
A variety of tools to help accurately pinpoint
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Male Fertility Enhancement
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If ordering from outside the UK or EU,
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News, Views and Reviews
Your favourite fertility
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TECHNOLOGYANDINDIVIDUALCARE.
We use the latest technology together with
an approach that focus on individual care. This
enables us to deliver great results also in the
more “difficult” cases where every step in the
treatment process must be individually tailored
to your unique needs.
EMBRYOGLUE-ATNOEXTRACOST.
All our couples at Klinikk Hausken benfit from the
use of EmbryoGlue technology to enhance im-
plantation of the most viable embryo. This service
is without any additional cost.
EMBRYOSCOPE®
TIME-LAPSETECHNOLOGY.
We are a European pioneer in the use of Embryo-
Scope®
. At no extra cost all our couples benefit
from our in-house experience with de-selection
parameters and kinetic behavior.
www.klinikkhausken.no

We’re delighted to welcome our newest Fertility Journeys partner into the fold – brilliant Scandinavian IVF leaders Klinnik Hausken. They’re
offering free treatment to a couple and numerous associated benefits including free testing, flights and accommodation.
Please read on to find out more about, as well as finding out how our existing partners and couples are getting on.
FERTILITY JOURNEYS 2015
...WITH FERTILITY GLOW
HOLISTIC FERTILITY
We’re delighted to announce that holistic programme creators Fertility Glow are now ready to offer a second
Fertility Road reader the chance to be a part of their new course. Founder and acclaimed holistic fertility expert
Kim Sjoblad talks us through the process.
The Fertility Glow Programme begins with a
comprehensive individual assessment, guiding
each couple through the eight-week step-by-
step journey, where they will learn to transform
mind, body and spirit. From the comfort of
their own homes, Fertility Glow participants
will receive weekly videos teaching them about
nutrition, how to deal with stress, and lifestyle
changes that can optimise their fertility.
In addition, participants will receive resources,
action guides, recipes and worksheets, custom-
designed to guide each participant on the path
towards overcoming any challenges that may
arise throughout their pregnancy journey.
I coach couples on the many holistic ways to
improve overall health and provide options for
preconception.Within my teachings, I connect
women and couples with the best holistic
approaches to achieve conception and to
sustain a long, healthy life.
As discussed, we are now taking
applications for a second Fertility Road
reader to work with Kim on her Fertility
Glow Programme with all costs paid. Each
programme lasts for eight weeks with the
next set to commence in the next two
months. If you are keen to be considered,
please email editor@fertilityroad.com,
outlining where you are on your fertility
journey at present.We welcome applicants
of all ages, from all backgrounds and at
any point along the fertility journey -
names and supporting information will be
passed to Kim for selection.
For more information on Kim Sjoblad, her
incredible story regarding fertility success,
and The Fertility Glow programme, please
visit kimsjoblad.com.

...WITH IVF SPAIN
At IVF Spain we are proud to announce that,
once again, we will be part of the exciting
project Fertility Journeys.This has been a
hugely original, inspirational, global project
that we have endorsed fully, and to sign
up for a third year is a privilege.After all,
we know how important it is for people
with fertility problems to fulfil their dream
of becoming parents. Considering that
treatment is provided free of charge for one
lucky couple, we hope that the economic
factors which control so much of our lives
should not always be a barrier to starting or
extending a family.
So for the third year, and together with the
support of the IVF Spain Foundation, a new
family will have the opportunity to start an
egg donation fertility treatment working with
the medical team of Dr Aizpurua.The IVF
Spain Foundation is a non-profit organisation
established by the IVF Spain fertility clinic
in 2012.The foundation focuses its efforts
on two essential aspects: supporting families
through the ‘Amadrina’ (sponsoring) social
programme, and committing to research,
training and teaching. Under the chairmanship
of Dr Jon Aizpurua, the multidisciplinary team –
committed to both causes – collaborates on a
daily basis for the IVF Spain Foundation to play
a significant role with families being helped.
The couple we have been supporting through
the journey,Anita and Simon, recently travelled
to Spain in order to make their latest visit to the
IVF Spain fertility clinic.They are very excited
about the treatment and are looking forward to
a happy conclusion – namely being able to form
the family they have always dreamed of.
They were due to come to IVF Spain on December
28 – when this piece was going to press – for an
echography and then on January 5, 2016 for their
embryo transfer.The doctors and the entire team
EGG DONATION
have put all their effort and hope into achieving
successful implantation and, of course, fulfilling
Anita and Simon’s dream.
IVF Spain pays special attention to providing
comfortable patient care. People sometimes
think that begins and ends with specialists, but
the reality is the attention to detail goes right
the way down to furniture distribution, the
colours used in each room and other elements
of decoration. Everything has been chosen
carefully following the Feng Shui principle
in order to make couples feel as settled and
relaxed as possible.We complement this with
holistic treatments such as acupuncture. These
kinds of treatments have been scientifically
demonstrated to improve responses to fertility
medication and, ultimately, increase pregnancy
rates. After all, a comfortable state of mind
promotes blood flow and relaxes patients
before and after treatment, thus significantly
reducing stress.
For our first update we visit our official clinic partners IVF Spain, following Anita and Simon’s challenging journey
with the Alicante-based experts.

But our attention to detail goes even
further.The therapeutic, technological and
biotechnological equipment found at IVF Spain
is exceptional compared to most Spanish clinics,
and as a result the clinic ranks among the most
advanced in Europe.We have a flow cytometer
for semen analysis, genetic tests to analyse the
endometrial receptivity, preconception genetic
testing to avoid monogenic diseases, protamine
tests to improve male fertility, specific genetic
screening protocols that improve the chances of
pregnancy, technologies to predict the viability
of embryos and many other technologies that
ensure our visitors are in the best and most
experienced hands.
IVF Spain devotes all its effort to obtaining and
retaining the best pregnancy rates and does not
hesitate when it comes to improving progress
and scientific knowledge.This line of action
has meant the consolidation of IVF Spain as a
globally regarded reference point in research
applied to assisted reproduction, as evidenced by
the recognition and the impact their scientific
work has had throughout 2015.
During the annual meeting of the American
Society of Reproductive Medicine – one of the
fertility world’s most important conferences,
where the latest developments in assisted
reproduction are disclosed – IVF Spain attracted
great interest with two revealing scientific
studies. Each study has demonstrated that the
use of the growth hormone on patients with
poor prognosis improves the implantation rate,
based on the use of a protamine ratio as a new
marker for male infertility.
Another important event for IVF Spain has been
its recent participation in the most important
national meeting on embryology organised by
the Association for the Study of Reproductive
Biology (ASEBIR), where the reproduction clinic
has been recognised for excellence in scientific
innovation by the Scientific and Organising
Committee. Out of the 11 presented studies
two important procedures were awarded the
highest honour:
EMBRYOBANKINGWITHPGS
Thanks to this technique embryos are generated
and accumulated after several cycles (usually
two to four) and ultimately analysed using
the Preimplantation Genetic Screening (PGS).
Its function is to detect both numerical and
structural chromosomal alterations with the
aim of transferring embryos with a normal
chromosomal content.The chromosomal
alterations increase with age, hence it is advisable
to apply the PGS to patients older than 38 years.
SPERMVITRIFICATION
Unlike traditional freezing, through this process
we achieve an improvement in survival of the
semen sample after cryopreservation.This
improvement allows patients to use the sample
obtained during the first visit.This way it is
possible to achieve better results and, hence, it
prevents the male partner from travelling the day
of the embryo transfer.
The aim of focusing on innovation and
technological advances in fertility lies in the need
to offer patients the highest pregnancy rates –
70% to 85% depending on the type of treatment
and placing the clinic above the Spanish average
according to the data provided by the SEF
(Spanish Fertility Society) – as well as providing
a satisfactory solution to the most complex and
difficult cases.
Repeated miscarriages, implantation failure
and male fertility factors are the primary
causes of not achieving pregnancy. Detection
is as important as applying an appropriate
treatment for each patient, hence IVF Spain has
a mechanism for an early detection of factors
that constitute the cause for not achieving a
successful pregnancy.
In short, in most cases, having a multidisciplinary
team at our disposal, capable of implementing
the advances in reproductive medicine, makes
a difference when trying to achieve the desired
pregnancy.
On behalf of the entire IVF Spain, we wish you
every success and happiness for 2016 and we
would like to send you our best wishes, that in
the year ahead all families can fulfil their dream
of conceiving a healthy baby.

Klinikk Hausken writes…
Individualised care together with the newest
technology and years of expertise makes
for a winning combination in getting great
results for our valued clients.We pride
ourselves on listening to our clients as the
answers often lie with the client and not
in the test results alone.And as one of the
pioneers in Europe to successfully implement
the EmbryoScope to its full potential with
amazing results, all our clients get free use
of this revolutionary technology.Although
Klinikk Hausken (KH) is the largest private
IVF clinic in Norway we are small compared
to any UK clinic.That’s why our clients
feel they have been seen and heard after
receiving treatment at the clinic.
With a strong legacy connected to IVF and over
20 years’ experience Dr Jon Hausken founded
Klinikk Hausken in 2006. Over the years the clinic
has become the largest private IVF clinic not just
based on number of clients, but also on birth
success rates.When Dr Hausken founded the
company he had a strong view on how the clinic
should be run. Basing the core values on individual
care, innovation and simplified treatment plans Dr
Hausken and his team have made the clinic a‘safe
haven’ for couples seeking IVF treatment.
OUR DOCTORS
KH’s practice is led by Medical Director and
founder Dr Jon Hausken. He completed his
MD in 1989 specialising in obstetrics and
gynecology in 1995. From then on he has
worked as both Head of the IVF and Birthing
Unit at Haugesund Hospital until he left to
start Klinikk Hausken in 2006, in doing so
carrying on his father’s legacy as an innovator
within the field of IVF. Dr Hausken is also the
Director of the Nordic Fertility Society (NFS)
and the national society (NOFAB).
Dr Arne Schwennicke joined the KH team of
doctors in 2008 after two years as Head of the
IVF unit at Haugesund Hospital. He specialised
...WITH KLINIKK HAUSKEN
IVF TREATMENT, SCANDINAVIA
It’s time to welcome our newest Fertility Journeys partner, Klinikk Hausken, and
to invite you to apply to work with them for free over the coming year.
Dr Godtlibsen completed her MD in 2002 and
has since worked at NHS equivalent hospitals in
Bergen, Stavanger and Haugesund specialising
in obstetrics and gynecology. She joined the
Stavanger branch in 2015.
So to summarise there is no doubt our patients
are in good hands whilst receiving treatment at
Klinikk Hausken.
OUR TEAM
Although KH is the largest private IVF clinic in
Norway we are small compared to any UK clinic.
That’s why our clients feel they have been seen
and heard after receiving treatment at the clinic.
All our clients will be given a named nurse who
will be a couple’s point of call throughout the
treatment process.
In addition, our clients get direct access to
their doctor to make sure they feel safe during
treatment. Our international contact is also at
Dr Jon Hausken
Klinikk Hausken have always been the pioneers in
adapting cutting edge technologies within IVF. We
maintain our focus on innovative treatments and
technologies designed to maximise success rates for
our couples. With innovation as the key word, Klinikk
Hausken in 2010 began implementing the revolutionary
EmbryoScope® Time-Lapse imaging technology.
in gynecology and obstetrics between 2000 and
2006 after completing his MD in 2001.
In addition, we are so happy to welcome our two
new colleagues to the KH team, Dr Holst-Larsen
and Dr Grete Dale Godtlibsen, both IVF experts
with years of experience in the field.
Dr Holst-Larsen completed his MD in 1998
and has since worked as both Head of the IVF
and birthing units in Stavanger and Haugesund
Hospital. He joined the KH team in 2014.
hand if our clients have any queries or concerns
regarding travel arrangements, appointments etc.
At every turn the KH team is there to ensure you
receive the individualised care KH is all about.
EMBRYOLOGY AND INNOVATION
Klinikk Hausken have always been the pioneers
in adapting cutting edge technologies within IVF.
We maintain our focus on innovative treatments
and technologies designed to maximise success
rates for our couples.With innovation as the
key word, Klinikk Hausken in 2010 began

KLINIKK HAUSKEN’S FERTILITY
JOURNEY – WHAT’S ON OFFER
Klinikk Hausken is really excited in joining
this year’s Fertility Journeys project. Our
team is ready to help the chosen couple
on their road to parenthood through the
use of IVF treatment. Medical Director Dr
Jon Hausken and his dedicated team will
guide the selected couple throughout their
treatment cycle.
The clinic will cover all costs in connection
with the IVF treatment as well as all travel
expenses and accommodation. If donor
sperm is needed Klinikk Hausken will also
cover these expenses. In the event of
surplus embryos the clinic will cryo preserve
these at no extra cost.And if the couple
need to use the cryo preserved embryos
due to a negative result on the fresh cycle,
Klinikk Hausken are similarly prepared to
cover any cost connected to this cycle.
The outline above also includes travel and
accommodation expenses.
If the couple gives birth on the fresh cycle
they are free to use the cryo preserved
embryos for sibling treatment at their
own expense.The embryos will be cryo
preserved for five years according to
Norwegian Law.
If you would like us to help you on your
Fertility Journey please apply by e-mailing
editor@fertilityroad.com detailing why
you would like to be chosen, and outlining
where you are on your fertility journey.We
welcome applicants between 20 and 40
years old, from all backgrounds and at any
point along your fertility journey.
implementing the revolutionary EmbryoScope®
Time-Lapse imaging technology.
We were the first clinic in Norway, as well as
one of the pioneers in Europe, to successfully
implement this novel concept.
Upon receiving its EmbryoScope, Klinikk
Hausken, led by IVF Laboratory Director
Shabana Sayed, began a series of in-house
trials to confirm its safety and efficacy.This
resulted in an algorithm which has allowed us
to achieve a relative increase in live birth rates
per embryo transferred by a remarkable 24%. It
uses, in addition to the traditional morphology,
deselection parameters and kinetic behavior of
embryos to select the most viable embryo.
The benefits of this technology has resulted
in Klinikk Hausken implementing the use of
EmbryoScope in all of our clinics and, more
importantly, has meant we can provide this
revolutionary technology to all couples without
any additional cost.
We strongly believe that time is of the essence
when trying to achieve a pregnancy.This is one
of the reasons why we use EmbryoGlue as the
standard embryo transferring media for all our
couples, irrespective of it being their first, second,
third, fourth or fifth attempt.
To enhance implantation of the most viable
embryo in the uterus, EmbryoGlue has been used
in all our couples from 2010.This transferring
solution acts as an adhesive assisting in successful
implantation and, subsequently, a healthy
pregnancy.This again reinforces Klinikk Hausken’s
approach of providing optimal care to all our
couples at no extra cost.
OUR CLIENTS
Most of our clients have already been through
a few rounds of fertility treatment by the
time they seek treatment at our clinic. Our
UK clients have usually been through the NHS
funded attempt or other privately funded
treatment.This is why KH specialise in ‘difficult’
cases, making sure no stone is left unturned to
optimise every step of the treatment process.
We pride ourselves on listening to our patients
as the answers often lie with the patient and
not in test results alone. Individualised care
together with the newest technology and years
of expertise makes for a winning combination in
getting great results for our valued clients.
MADE IN THE LAND OF THE VIKINGS
By having your treatment in Norway you won’t
just get excellent care in all aspects of your
treatment, but you will get an adventure. Come
see the beautiful fjords and mountains Norway
has to offer - Klinikk Hausken has three
branches set along the beautiful west coast.
You will find us in Stavanger, Haugesund and
Bergen. Each base is run with the same vision
Dr Hausken had when he first started his IVF
clinic. Find out more by visiting our website at
klinikkhausken.no/en/travel-information-2.
CONTACTING KLINIKK HAUSKEN
Klinikk Hausken’s team is available via email,
telephone and through our online webpage
form. Please go to klinikkhausken.no/en for
more information.

...WITH LISTER FERTILITY CLINIC
Dr Thum writes…
Following on from the last issue Christina has
been matched with a recipient and started
another egg sharing IVF treatment.After
going through the data obtained from her
last stimulation cycle, I have modified her
stimulation protocol slightly; hopefully it will
help to achieve a better outcome.
At Lister we routinely invite couples to come back
for a follow-up appointment after a failed cycle.
We will use the information that we obtained
from their last failed cycle to tailor a better
stimulation protocol for a future treatment cycle.
In Christina’s case I agreed that she should have an
endometrium scratch to enhance implantation.
Christina started her treatment cycle in
November – she had 13 days of injection for
stimulation and during that stimulation period
she attended the Lister clinic five times to
monitor her follicular growth, and she was
subsequently ready for egg collection in mid-
November. Her response to the stimulation
in this cycle was very good: she had more
follicles than in her previous cycle.At Lister
we routinely monitor the patient’s oestrogen,
LH and progesterone levels during stimulation
cycles.We would only proceed to do vaginal egg
collection when the blood test levels are at the
optimum level with satisfactory follicular size.
After 13 days of stimulation Christina’s
oestrogen levels were very good and had
a good number of follicles. However, her
progesterone levels were elevated. From our
data and medical publications it shows that if
the progesterone levels are elevated before egg
collection the chances of achieving a pregnancy
are significantly lower.This is most likely due
to the endometrium maturation being out
of synchronisation with the implantation of
embryo.Therefore I advised Christina to proceed
with egg collection but to freeze all the embryos
at two pronuclear stage, instead of having
fresh embryo transfer. From our experience
of performing frozen embryo transfer in this
situation the chances of achieving a pregnancy
is as good as when having fresh embryo transfer.
Christina produced 13 eggs – she donated
six eggs and kept the rest for her own use.
ICSI was performed on six eggs, five achieved
fertilisation and four embryos were frozen at
the two pronuclear stage. The egg collection
was uneventful and Christina had a speedy
recovery from the procedure.
Christina was understandably upset that she did
not have a fresh embryo transfer. I invited her to
come for a follow-up appointment to discuss the
future plan for her frozen embryo transfer which
will be done on her natural cycle. Christina is keen
to get on with the treatment and I agreed that
we would try to have this done in December… so,
by the time you read this.
Christina called the nurses at the beginning of
December when her period started – she had
a baseline scan to assess her lining and her
ovaries in view of planning for frozen embryo
transfer in this natural cycle.The scan showed
a satisfactory endometrium but her ovaries
were still quite swollen from her egg collection.
Christina was sent home and would go on to
book another scan on day 10 of her cycle.The
scan on day 10 still showed that her lining has
not developed yet. I suggested that we continue
to monitor her cycle and hopefully we can do
the frozen embryo transfer in this cycle; if not
we will do it in her next cycle.
Christina has four embryos in storage which
appear to be good quality embryos and I think
she has a good chance to achieve a positive
outcome for her forthcoming frozen embryo
transfer treatment. If that is not the case, I will
continue to work with the couple to help them
achieve their goal.
EGG SHARING
Christina produced 13 eggs - she donated
six eggs and kept the rest for her own
use. ICSI was performed on six eggs, five
achieved fertilisation and four embryos were
frozen at the two pronuclear stage.

Christina writes...
We are now about to embark on our second
round of IVF – we have been matched
very quickly and cannot wait to get things
started again!
As we have already gone through the procedure
once before we feel more confident as we
know what to expect.
After things didn’t work out the first time, we
had our follow-up appointment with Dr Thum
which we found very useful. He was able to
look at our last cycle and modify this new one
to suit our needs better as there was data to
look at. Upon looking at our last cycle Dr Thum
made changes which will hopefully give us the
positive outcome we so desperately want.
Dr Thum increased our dose of medicated
injections as he now knows how I respond to
them without overstimulating me, and also
said we should have the endometrium scratch
to help with implantation.When we left we
felt reassured that Dr Thum was making all the
changes he could to help us this time round.
The first step into our IVF cycle was to
have the scratch performed. This was quite
uncomfortable but only lasted for a few
seconds, and it was worth all the pain as it’s
another step closer to making our dream come
true. Once this was done we were called in to
collect our bag of medication and start the
injections the next day.
As we have done the process before the
injections felt okay and quite normal. To be
honest, it becomes part of a nightly routine.We
had our routine scans throughout to check that
the follicles were growing nicely, which they
were. After 13 days stimulating we were ready
for egg collection; we couldn’t believe how
quickly it came around and that this was really
happening again. For some reason we felt quite
relaxed through the whole process this time; I
think it’s because we knew what to expect at
each scan.
On the day before we were booked in for
egg collection we were called by Dr Thum
who advised that everything looked great.
We had more follicles this time, though
unfortunately my progesterone level was
slightly raised which meant that while we could
go ahead with the scheduled egg collection
the transfer would have to be postponed as
my chances would have been significantly
lower if we were to proceed straight away. On
that note Dr Thum did the best thing for us
and decided we do a ‘freeze all’ cycle so my
eggs would be protected and we could still use
them, albeit it at a later date.
I was a bit upset but realised this was the best
thing for us to do and was happy DrThum checked
the levels so our eggs would not be wasted.
Egg collection went well with 13 eggs
collected – we gave six away and kept seven
for ourselves.We were really happy that we
had more this time. I had no issues with the
procedure and went home a few hours later.
We had the call the following day advising
us that four were fertilised with ICSI and
were frozen for us the same day. This was
an amazing achievement for us: during the
last cycle, only one had fertilised, so you can
imagine how relieved and happy we were.
I wanted to move on to the next step as quickly
as possible. I felt a bit empty and wanted my
eggs back where they belonged so Dr Thum
agreed that we would start on my next period.
I was called in to go through the procedure as
we haven’t done a frozen transfer before. It all
seemed quite straightforward with no daily
injections involved and a few scans to monitor
my lining as this was a natural frozen transfer.
When my period started I went to Lister for
my baseline scan to see how everything was
looking. It was okay but my ovaries were still
quite inflamed from the egg collection and a
few bruises were seen, so I was told to come
back to see if they reduced as we really wanted
to go ahead whilst not risking losing our
precious embryos.When we went back for our
day 10 scan it still showed large ovaries and my
lining had not thickened enough to continue
with the frozen embryo transfer. Again, this
was quite upsetting but you cannot rush these
things – I have realised that now. The body
needs time to heal and my embryos need to be
put back into the best environment possible.
We really want this to work this time round so
to wait a few more weeks to my next period is
the best thing for them.
Our journey continues but we are so close and
we know that Dr Thum has done everything
he can to make this work, and of course, we
remain very optimistic and excited.
I was called in to go
through the procedure
as we haven’t done a
frozen transfer before.
It all seemed quite
straightforward with
no daily injections
involved and a few
scans to monitor my
lining as this was a
natural frozen transfer.

Founded in 1989 with the goal of building
the best fertility programme possible, ORM is
globally recognised for its consistently high
live birth success rates, individualised care,
and innovation leadership. In 1999, ORM’s
innovation led it to utilise the expertise of Intel
clean room facility engineers, to develop its
pioneering embryology laboratory clean room,
one of the ﬁrst in the world. More recently, this
same drive to embrace the latest technologies
to achieve the best outcomes has been behind
ORM’s commitment to making industry-
leading genetic screening and testing available
to its patients.
ADVANCED GENETICS AT ORM
The understanding of genetics and the variety
of tests available are both expanding rapidly.We
believe that our patients should feel empowered
to make informed decisions based on the latest
technology and with accurate, up-to-date, and
easy to understand information. Separating it
from most other clinics, ORM has an in-house
state-of-the-art genomics programme.We have
a team of highly-experienced, full-time, genetics
counsellors who work with patients and are
involved in the screening of every egg donor in
ORM’s in-house programme. ORM is also one
of the only IVF clinics in the USA that has an on
site genetics laboratory.
When it comes to genetic screening and testing
it is important for patients to understand their
options and the differences between pre-embryo
creation and post-embryo creation screening
and testing.
PRE-EMBRYO CREATION
With pre-embryo creation it is possible to
gather genetic history-focused data and
conduct recessive carrier gene screening on
each individual contributing eggs and sperm
for the creation of embryos.
By collecting and analysing family genetic history,
ORM’s genetics counsellors help identify areas that
may warrant further investigation and/or testing.
Through a saliva or blood sample it is possible to
screen whether individuals contributing eggs and
sperm for the creation of embryos are carriers
for a recessive genetic disease.
The person being tested may not suffer from the
disease being tested, but still be a carrier.
About 35% of people who we test at ORM are
carriers for recessive genetic diseases. If both
people contributing eggs and sperm are carriers
for the same disease then there is an increased risk
that a baby would develop that genetic disease.To
...WITH OREGON REPRODUCTIVE MEDICINE
DONOR EGG IVF
The application period for Oregon Reproductive Medicine’s Fertility Journey – a donor
egg IVF cycle working with an ORM egg donor – has now closed and the team is
evaluating all the applications received. While this is ongoing, we share details of the
genetic screening and testing that ORM is a leader in making available for patients.
minimise this risk for patients, we automatically
test everyone who is contributing eggs and sperm
for 100 recessive carrier genetic diseases.This is a
signiﬁcantly more comprehensive process than is
standard among many clinics.
The results of this pre-embryo creation genetic
screening are available to patients before they
commence their cycle and/or select a donor if
that is part of their treatment and helps them
make informed choices.
POST-EMBRYO CREATION
Pre-implantation genetic screening (PGS) and
pre-implantation genetic diagnosis (PGD) are
the two forms of post-embryo creation genetic
screening which patients should understand.
PGS involves the testing of embryos to determine
whether they carry the correct number of
chromosomes to develop into a healthy pregnancy
and baby. Embryos with the incorrect number of
chromosomes will typically not develop, resulting
in a failed IVF cycle or miscarriage, or a baby
with one of several conditions – most of which
are incompatible with life but which also include
Down Syndrome.The most advanced form of
PGS involves testing all of the chromosomes by a
technique known as Comprehensive Chromosome
Screening (CCS).At ORM we utilise the most
newest, powerful version of this technique called
Next-Generation Sequencing (NGS).
The formation of abnormal embryos (not
possessing the correct number of chromosomes)
is a natural phenomenon – around 25% of
embryos from a young woman’s eggs will be
naturally abnormal and this rate increases with
the age of a woman’s eggs.These embryos will
not make healthy babies and in most cases
miscarry or do not implant at all. Because of
this, CCS is a form of standardised genetic
screening that is appropriate for every patient to
consider as part of their IVF treatment and as a
means to optimise the chances for success.
Pre-Embryo
Creation
Genetic History
Evaluation
Recessive Carrier
Gene Screening
Post-Embryo
Creation
Pre-implantation
Genetic Screening (PGS)
Pre-implantation
Genetic Diagnosis (PGS)

OREGON REPRODUCTIVE MEDICINE
ORM’s global practice is led by Dr John Hesla and Dr Brandon
Bankowski, who have helped patients from over 40 countries create
their families. Both completed their training at the Johns Hopkins
Hospital – ranked as the number one in the USA for over 20 years in a
row – and are recognised internationally for their professional excellence
and commitment to improving their patients’ reproductive care.
Dr Hesla joined ORM in 1999 when he co-founded its IVF programme
and was instrumental in building ORM’s pioneering embryology
laboratory clean room, one of the first in the world. Dr Bankowski joined
ORM in 2005 and he co-founded its industry-leading in-house genomics
programme. Both strive to help patients achieve the best success while
caring for the genetic health of their family.
ORM moved into its new state-of-the-art Fertility Center located
in vibrant downtown Portland in autumn 2015. It is home to our
100-strong ORM family of doctors, nurses, embryologists, genetic
counsellors, psychologists, patient co-ordinators, donor co-ordinators,
and financial counsellors among others.This world-class facility
comprises 25,000 square feet and four floors of patient care facilities.
ORM’s Fertility Center houses its embryology and genetics laboratories,
and increased space for ORM’s fertility services and treatments,
including IVF, egg donation, surrogacy, advanced genetic screening, as
well as comprehensive fertility counselling, acupuncture, community
education and proactive fertility care.
ORM’s new Fertility Center builds on our commitment to achieve the
highest success rates while providing a customised, compassionate
patient experience.
We look forward to welcoming you to ORM in Portland and to help you
build your family!
PGD involves the testing of embryos to
determine whether a patient-specific genetic or
chromosomal disorder is present. PDG testing is
therefore customised and is only appropriate in
certain circumstances with select patients.
COMPREHENSIVE CHROMOSOME
SCREENING (CCS)
In every IVF cycle embryos are first examined
under the microscope in order to select the best-
looking ones. In addition to this visual inspection
of the embryos, it is possible to count the number
of chromosomes in each embryo. Chromosomes
are packages of genes, or DNA, which are present
in every cell of a person. Normally, there are 46
chromosomes (23 pairs) in each cell. Embryos
with the correct number of chromosomes have
the best potential for implanting and resulting in
a successful pregnancy.
Abnormalities in chromosome number (extra or
missing chromosomes) are the most common
cause of failed implantation in IVF cycles and
miscarriages, and are the only type of problem
that becomes more common as women get older.
CCS is the term for this type of testing.This
process involves the precise laser removal from an
embryo of about five cells that would otherwise
develop into the placenta at the blastocyst (day
Dr John HeslaDr Brandon Bankowski
The ORM team
five to six) stage.The biopsied cells are laboratory
tested using advanced technology to determine
the number of chromosomes present.The
embryos are generally frozen for future transfer
while the testing is being performed, but in select
circumstances (based on the development of the
embryos and availability of an in-house genetics
testing laboratory as is the case at ORM) it is
possible to complete the testing and transfer the
selected embryo(s) prior to freezing.
Transferring only embryos with the correct
number of chromosomes can often improve
the chances of a successful pregnancy and
also decrease the chance of suffering through
a miscarriage or having a baby born with a
disorder linked to a chromosomal abnormality.
CCS can be especially helpful for patients who are:
• Women 35 years of age or older using their
own eggs
• Couples who have a history of repeated
miscarriage
• Couples who have had a pregnancy or baby
with a chromosomal abnormality
• Couples who have had multiple failed IVF cycles
However, embryos with an incorrect number of
chromosomes are very common, can occur at any
age, and are not related to one’s family history so
CCS is an option for all patients undergoing IVF.
New research shows that CCS can improve the
implantation rates of embryos from egg donors who
are in their twenties. Currently, at ORM over 80% of
IVF patients now choose CCS as part of their cycle.
CCS USING NEXT-GENERATION
SEQUENCING (NGS)
CCS using NGS technology is the most advanced
form of this screening. Compared to conventional
technology, NGS involves the attachment of several
hundred thousand genetic probes to each biopsied
cell. NGS technology delivers the greatest accuracy
and speed for CCS procedures. ORM’s in-house
genetics laboratory employs NGS technology.
CCS is a form of
standardised genetic
screening that is
appropriate for every
patient to consider
as part of their IVF
treatment and as a
means to optimise the
chances for success.

Quote reference
Do you need IVF? If so, you may be able to help yourself and
another woman. By sharing your eggs, you could receive
standard IVF treatment free at The Lister Fertility Clinic,
one of London’s top fertility centres.
t: 020 7881 4036
e: eggdonation@lfclinic.com
w: www.needivf.co.uk
Need IVF but
can’t afford it?
If you’re 21-35, need IVF
and are happy to share
your eggs, please contact
The Lister Fertility Clinic
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Where can I do surrogacy? What about egg donation? Do I need a lawyer? What are the US options? What
are the Mexico options? Can I do surrogacy in Ukraine? Surrogacy in Greece? What does an agency do?
What are the latest IVF advances? PGD Testing? Where do I go for support? Where do I start? Does my
name go on the birth certificate? How do I tell my child? What does my surrogate expect? Can I use my
own embryos? How do I choose an IVF clinic? What is Traditional surrogacy? What is gestational surrogacy?
Can I get insurance? How do I obtain a passport? Can my sister be my surrogate? Can my mother be my
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A newborn baby cries while it is held by a nurse in the
Neonatal Intensive Care Unit of the Mofid Children’s
Hospital in Tehran, Iran. Having curbed birth rates for two
decades, Iran is once again promoting a baby boom to help
make up for its greying population, but experts say it is
difficult to encourage Iranians to have more children under
a sanctions-hit economy and rapid inflation.

IVF IN BARBADOS =
SUCCESS!
Many UK coupes are heading to the Caribbean island
of Barbados for successful fertility treatment.
Why?
INDIVIDUALISED CARE
Increasing YOUR success rates
RELAXING ENVIRONMENT
on site spa so YOU are at your optimum to undergo IVF
HIGH SUCCESS RATES
80% for women under 35, giving YOU the BEST chance of success
LOW COST
under £4000 for full IVF cycle, making treatment affordable for YOU
DONOR EGGS
Excellent donor egg programme, especially for Afro Caribbean
couples
JCI ACCREDITATION
assuring YOU of world class standards
At Barbados Fertility Centre it's all about YOU,
so call us TODAY and take charge of YOUR treatment.
001 246 435 7467
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