1. Selective gut decontamination with oral and rectal antibiotics can decrease mortality and need for laparotomy in severe acute pancreatitis. 2. Indications for surgery in severe acute pancreatitis include infected necrosis, pancreatic abscess, local complications, bleeding, bowel perforation, and portal vein thrombosis. 3. Several surgical techniques are used to treat infected necrosis including open packing, zipper techniques, and closed lavage methods, but there is no consensus on the best approach.