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‫الرحيم‬ ‫الرحمن‬ ‫هللا‬ ‫بسم‬
Glandular epithelium
Dr. Sara Yousif Alshreef
⦿A gland is a single cell or a mass of epithelial cells
adapted for secretion.
⦿Glands are composed predominantly of epithelial
tissue with supporting connective tissue
⦿Embryological development is from tiny
invaginations (infoldings) or evaginations
(outfoldings) of membranous epithelia.
⦿There are two types of glands depending on how
the cells release the substances they produce:
 Exocrine glands
 Endocrine glands
⦿Exocrine glands have ducts (tubes) to take the
secretion away from the gland to the site of its
function.
⦿secrete their products into ducts that empty onto the
surface of covering and lining epithelium such as the
skin surface or the lumen of a hollow organ
⦿ Salivary glands, for example, secrete saliva that is
carried by ducts to the oral cavity. Sweat glands
secrete sweat that is transported by ducts to the skin
surface.
⦿Exocrine glands within the skin include oil (sebaceous)
glands, sweat glands, and mammary glands. Exocrine
glands within the digestive system include the salivary
and pancreatic glands
⦿On the basis of their structures exocrine glands are
classified as
 Unicellular glands: Unicellular glands are single-
celled glands, such as goblet cells . That occur
within most epithelial tissues. Goblet cells are
found in the epithelial linings of the respiratory
and digestive systems
 Multicellular glands: As the name implies, the
glands composed of both secretory cells and cells
that form the walls of the ducts
Mucin
Goblet
cell
Lamina
propria
EPI
.Tissue
⦿Multicellular glands are further
classified on basis of three criteria:
(1) Structure of Ducts:
(2) Shape of the secretory portion:
(3) Method of release of product
⦿ Classification based on Structure of Ducts
 Simple: If the duct of the gland does not
branch, it is a simple gland
 Compound: If the duct branches, it is a
compound gland.
Classification based on shape of Secretory portion
• A:Tubular Gland:
• if the secretory portion resembles a tube then this will
called as Tubular gland.
• B: Acinar glands:
• In this case the secretory portion resembles a flask or
a dilated Sac and the Sac will be called as Acinus or
Alveolor.
• C: Tubuloacinar glands:
• Multicellular glands with a secretory portion that
resembles both a tube and a flask are termed as
tubuloacinar glands.
Classification based on mode of release
⦿Merocrine gland:
⦿ synthesize their secretions on ribosomes attached to
rough ER; process and package them at the Golgi
complex; and release them from the cell in secretory
vesicles via exocytosis
⦿Examples include tear glands, pancreas, gastric glands.
Apocrine glands:
⦿accumulate their secretory product at the apical
surface of the secreting cell. Then, that portion of
the cell pinches off by exocytosis from the rest of
the cell to release the secretion. The remaining
part of the cell repairs itself and repeats the
process
⦿Examples are Mammary glands and some sweat
gland. Provides nourishment to infant and regulate
body temperature.
Holocrine gland
⦿accumulate a secretory product in their cytosol. As
the secretory cell matures, it ruptures and
becomes the secretory product.
⦿Because the cell ruptures in this mode of secretion,
the secretion contains large amounts of lipids from
the plasma membrane and intracellular
membranes.
⦿The sloughed off cell is replaced by a new cell.
⦿Example is sebaceous gland which release thick
secretion to prevent skin from drying.
Glands are classified not only by their structure but also by
nature of their secretions.
⦿ Serous glands produce relatively thin, watery fluids such
as perspiration, milk, tears, and digestive juices.
⦿ Mucous glands, found in the tongue and roof of the mouth
among other places, secrete a glycoprotein called mucin.
After it is secreted, mucin absorbs water and forms the
sticky product mucus.
⦿ Mixed glands, such as the two pairs of salivary glands,
contain both serous and mucous cells and produce a
mixture of the two types of secretions.
⦿ Cytogenic glands release whole cells. The only examples
of these are the testes and ovaries, which produce sperm
and egg cells.
glands - called “ductless glands”
⦿Endocrine
discharge their secretions into the intracellular
where it diffuses into
fluid,
These secretions are hormones,
the blood stream.
or chemical
messengers, which regulate many bodily functions.
Glandular epithelium.pdf

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Glandular epithelium.pdf

  • 1. ‫الرحيم‬ ‫الرحمن‬ ‫هللا‬ ‫بسم‬ Glandular epithelium Dr. Sara Yousif Alshreef
  • 2. ⦿A gland is a single cell or a mass of epithelial cells adapted for secretion. ⦿Glands are composed predominantly of epithelial tissue with supporting connective tissue ⦿Embryological development is from tiny invaginations (infoldings) or evaginations (outfoldings) of membranous epithelia. ⦿There are two types of glands depending on how the cells release the substances they produce:  Exocrine glands  Endocrine glands
  • 3. ⦿Exocrine glands have ducts (tubes) to take the secretion away from the gland to the site of its function. ⦿secrete their products into ducts that empty onto the surface of covering and lining epithelium such as the skin surface or the lumen of a hollow organ ⦿ Salivary glands, for example, secrete saliva that is carried by ducts to the oral cavity. Sweat glands secrete sweat that is transported by ducts to the skin surface. ⦿Exocrine glands within the skin include oil (sebaceous) glands, sweat glands, and mammary glands. Exocrine glands within the digestive system include the salivary and pancreatic glands
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  • 5. ⦿On the basis of their structures exocrine glands are classified as  Unicellular glands: Unicellular glands are single- celled glands, such as goblet cells . That occur within most epithelial tissues. Goblet cells are found in the epithelial linings of the respiratory and digestive systems  Multicellular glands: As the name implies, the glands composed of both secretory cells and cells that form the walls of the ducts
  • 7. ⦿Multicellular glands are further classified on basis of three criteria: (1) Structure of Ducts: (2) Shape of the secretory portion: (3) Method of release of product ⦿ Classification based on Structure of Ducts  Simple: If the duct of the gland does not branch, it is a simple gland  Compound: If the duct branches, it is a compound gland.
  • 8. Classification based on shape of Secretory portion • A:Tubular Gland: • if the secretory portion resembles a tube then this will called as Tubular gland. • B: Acinar glands: • In this case the secretory portion resembles a flask or a dilated Sac and the Sac will be called as Acinus or Alveolor. • C: Tubuloacinar glands: • Multicellular glands with a secretory portion that resembles both a tube and a flask are termed as tubuloacinar glands.
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  • 11. Classification based on mode of release ⦿Merocrine gland: ⦿ synthesize their secretions on ribosomes attached to rough ER; process and package them at the Golgi complex; and release them from the cell in secretory vesicles via exocytosis ⦿Examples include tear glands, pancreas, gastric glands.
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  • 13. Apocrine glands: ⦿accumulate their secretory product at the apical surface of the secreting cell. Then, that portion of the cell pinches off by exocytosis from the rest of the cell to release the secretion. The remaining part of the cell repairs itself and repeats the process ⦿Examples are Mammary glands and some sweat gland. Provides nourishment to infant and regulate body temperature.
  • 14. Holocrine gland ⦿accumulate a secretory product in their cytosol. As the secretory cell matures, it ruptures and becomes the secretory product. ⦿Because the cell ruptures in this mode of secretion, the secretion contains large amounts of lipids from the plasma membrane and intracellular membranes. ⦿The sloughed off cell is replaced by a new cell. ⦿Example is sebaceous gland which release thick secretion to prevent skin from drying.
  • 15. Glands are classified not only by their structure but also by nature of their secretions. ⦿ Serous glands produce relatively thin, watery fluids such as perspiration, milk, tears, and digestive juices. ⦿ Mucous glands, found in the tongue and roof of the mouth among other places, secrete a glycoprotein called mucin. After it is secreted, mucin absorbs water and forms the sticky product mucus. ⦿ Mixed glands, such as the two pairs of salivary glands, contain both serous and mucous cells and produce a mixture of the two types of secretions. ⦿ Cytogenic glands release whole cells. The only examples of these are the testes and ovaries, which produce sperm and egg cells.
  • 16. glands - called “ductless glands” ⦿Endocrine discharge their secretions into the intracellular where it diffuses into fluid, These secretions are hormones, the blood stream. or chemical messengers, which regulate many bodily functions.