Poster presentation at Florida Geriatric Society Symposium on August 5-6, 2017 at Orlando, Florida, USA. Diabetic neuropathy prevalence. Symptom of numbness, tingling, pain and swelling in lower extremities is due an inflammatoary process caused by a range of chemical mediators. The chemical mediators are derived from leukocytes, macrophages, platelets, endothelium, nerves and plasma. These mediators can be blocked by phytochemicals extracted from spices and herbs with massage oils.