CBD has been widely used for various medical conditions ranging from pain relief to epilepsy. However, its mechanism of action has yet to be defined. Current concepts are presented in these slides.

2. Routes of administration of CBD
● Oral Consumption
○ CBD Oil/Tinctures
○ CBD Capsules/Pills
● Edibles
○ CBD-infused Foods
● Inhalation
○ CBD vaping
● Topical Applications
○ CBD Creams/Lotions
● Transdermal Patches
● Sublingual Sprays
● Rectal Suppositories

3. CBD and Pain Relief Mechanisms
Current concepts of how CBD may provide pain
relief and the mechanisms behind its effects
https://chat.openai.com/c/f9b7e75d-32d9-4450-8e8f-863be1d94bf2

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Introduction to CBD and Pain
Relief Mechanisms
CBD has gained attention for its potential
therapeutic properties, including pain relief
CBD (cannabidiol) is a compound found in
the cannabis plant

5. ● CBD has anti-inflammatory properties
● Inflammation is a key component of many
types of pain
Anti-Inflammatory Effects
● CBD could potentially alleviate pain
associated with conditions like arthritis

6. Interaction with Endocannabinoid
System (ECS)
● The body has an endocannabinoid
system (ECS) composed of
receptors (CB1 and CB2) and
endocannabinoids
● ECS plays a role in maintaining
homeostasis, including pain
regulation
● CBD is thought to interact with the
ECS, potentially leading to pain
relief

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02
03
Impact release and
uptake of
neurotransmitters like
serotonin and
dopamine
Neurotransmitter Modulation
CBD might influence
neurotransmitter
signaling
Play roles in pain
perception, mood, and
overall well-being

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02
03
TRPV1 Receptor Modulation
CBD's interaction with TRPV1 might
contribute to its pain-relieving effects
CBD affects the TRPV1 receptor
TRPV1 receptor is involved in pain
perception and temperature regulation

9. ● CBD could impact the way pain signals are
processed by the nervous system
● Influence the "gate control theory of pain"
Pain Gate Control
● Non-painful input can close the "gates" for
painful input, reducing pain perception

10. Peripheral Nerve Endings
● CBD may influence the function of TRPV1
receptors on peripheral nerve endings
● Activation of these receptors can lead to pain
and inflammation
● CBD's interaction with these receptors might
help in dampening pain signals
CBD

11. 01
02
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Some components of
CBD may have effects
on the central nervous
system
Central Nervous System Effects
Topical CBD might
permeate the skin and
reach the bloodstream
These effects could
contribute to pain relief

12. Thank you
Any Questions
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