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Anatomy
Scleral layer
• Tenon capsule : contain elastic tissue and collagenous fibers . From limbus to optic
nerve
• Episclera : vascular layer . In the presence of inflammation this becomes very red
and congested (Episcleritis). Becomes thinner toward the back of the eye
• sclera proper : collagen ꟾ and proteoglycans
• Lamina fusca : innermost part of sclera . Brown because of melanocytes . Contain
collagen and fibroblast and melanocyte. Separated from choroid by perchoroidal
space
Special regions of Sclera
• Scleral sulcus : a furrow on inner surface of ant point of sclera . It houses
Schlemm's canal
• Scleral spur : circular rim in anterior part of sclera lying deep to Schlemm's
canal /a protrusion of the sclera into the anterior chamber.
• Lamina cribrosa : optic nerve passes throw it
Nerve supply to sclera
• Anterior part : long ciliary nerve
• Posterior part : short ciliary nerve
Blue sclera
• Buphthalmia
• High myopia
• Osteogenesis imperfecta
• Thinning of sclera like as necrotizing scleritis
• Marfan’s syndrome
Episcleritis
• Inflammation of episcleral layer
• Clinical manifestation : Red eye , redness disappear after utilization of
phenylephrine drop , foreign body sensation
• No affect on visual acuity
• 2 types : Diffuse . Nodular
Treatment of episcleritis
• Resolve spontaneously
• Systemic evaluation is not recommended except in recurrency
• Cold compress
• Topical and systemic NSAID
(indomethacin 250 TDS or flurbiprofen 300 qd)
• Topical corticosteroid
Scleritis
• Inflammation of scleral proper
• Female > male
• 50% bilateral
• 2 types : anterior (98%) , posterior
Symptoms and sign
• Pain
• Redness
• lacrimation
• Photophobia
• Diminution of vision
• If redness disappear after phenylephrine drop is episcleritis but if still persist
then scleritis
Classification
Anterior diffuse scleritis
Nodular anterior scleritis
Necrotizing scleritis with inflammation
Scleromalacia performance
Scleromalacia performance
• Elderly females with long standing RA
• Thin sclera through which the uveal tissue shines
• Spontaneous perforation rare
• If IOP increased then create anterior staphyloma
Posterior scleritis
• Diagnosis is difficult
• Pain and diminution of vision
• Associated with RA or systemic vasculitis
Lab test
• CBC , ESR , ANA , RF , ANCA
• Ig , serum proteins
• Uric Acid
• PPD
• VDRL , FTA-ABS
• CXR for sarcoidosis , Wegener , TB
• Paranasal sinus CT for Wegener
• Lumbosacral and SIJ xray for AS
• fluorescein angiography
Sclera

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Sclera

  • 1.
  • 3. Scleral layer • Tenon capsule : contain elastic tissue and collagenous fibers . From limbus to optic nerve • Episclera : vascular layer . In the presence of inflammation this becomes very red and congested (Episcleritis). Becomes thinner toward the back of the eye • sclera proper : collagen ꟾ and proteoglycans • Lamina fusca : innermost part of sclera . Brown because of melanocytes . Contain collagen and fibroblast and melanocyte. Separated from choroid by perchoroidal space
  • 4.
  • 5.
  • 6.
  • 7. Special regions of Sclera • Scleral sulcus : a furrow on inner surface of ant point of sclera . It houses Schlemm's canal • Scleral spur : circular rim in anterior part of sclera lying deep to Schlemm's canal /a protrusion of the sclera into the anterior chamber. • Lamina cribrosa : optic nerve passes throw it
  • 8.
  • 9.
  • 10. Nerve supply to sclera • Anterior part : long ciliary nerve • Posterior part : short ciliary nerve
  • 11. Blue sclera • Buphthalmia • High myopia • Osteogenesis imperfecta • Thinning of sclera like as necrotizing scleritis • Marfan’s syndrome
  • 12. Episcleritis • Inflammation of episcleral layer • Clinical manifestation : Red eye , redness disappear after utilization of phenylephrine drop , foreign body sensation • No affect on visual acuity • 2 types : Diffuse . Nodular
  • 13.
  • 14. Treatment of episcleritis • Resolve spontaneously • Systemic evaluation is not recommended except in recurrency • Cold compress • Topical and systemic NSAID (indomethacin 250 TDS or flurbiprofen 300 qd) • Topical corticosteroid
  • 15. Scleritis • Inflammation of scleral proper • Female > male • 50% bilateral • 2 types : anterior (98%) , posterior
  • 16. Symptoms and sign • Pain • Redness • lacrimation • Photophobia • Diminution of vision • If redness disappear after phenylephrine drop is episcleritis but if still persist then scleritis
  • 22. Scleromalacia performance • Elderly females with long standing RA • Thin sclera through which the uveal tissue shines • Spontaneous perforation rare • If IOP increased then create anterior staphyloma
  • 23. Posterior scleritis • Diagnosis is difficult • Pain and diminution of vision • Associated with RA or systemic vasculitis
  • 24.
  • 25. Lab test • CBC , ESR , ANA , RF , ANCA • Ig , serum proteins • Uric Acid • PPD • VDRL , FTA-ABS • CXR for sarcoidosis , Wegener , TB • Paranasal sinus CT for Wegener • Lumbosacral and SIJ xray for AS • fluorescein angiography