Map macmillan learning Indicate whether each of the following substances is soluble or insoluble in body fluids Soluble Insoluble glycogen phospholipids Carbon dioxide, CO2 Ca2 testosterone arginine glucose Solution Ans. # Soluble in body fluid: Glycogen, phospholipids, CO 2 , Ca 2+ , arginine, glucose # Insoluble in body fluid – Testosterone. # Glucose is a poly-hydroxy aldose. The O and H-atoms of –OH group in glucose forms hydrogen bonds with water molecules. Thus, glucose is soluble in water. # Glycogen is a polymer of glucose. Because of numerous polar –OH groups exposed to the surface, glycogen is also soluble in water. # CO 2 is converted into H 2 CO 3 – both non-enzymatically as well as enzymatically in the body fluid. The resultant carbonic acid and bicarbonate ions are highly soluble in water, CO 2 (g) + H 2 O <-----> H 2 CO 3 (aq) <---------> H + (aq) + HCO 3 - (aq) # Ca 2+ ions are highly soluble in water due to ionic interactions between Ca 2+ ions and water molecules in the body fluid. # Arginine is a basic amino acid, it has polar groups as well as positively charged side chain at physiological pH. SO, it’s also soluble in the aqueous environment of the body fluid. # Testosterone has a bulky, non-polar steroid nucleus, and is insoluble in body fluid or water. .

1. Map macmillan learning Indicate whether each of the following substances is soluble or
insoluble in body fluids Soluble Insoluble glycogen phospholipids Carbon dioxide, CO2 Ca2
testosterone arginine glucose
Solution
Ans. # Soluble in body fluid: Glycogen, phospholipids, CO 2 , Ca 2+
, arginine, glucose
# Insoluble in body fluid – Testosterone.
# Glucose is a poly-hydroxy aldose. The O and H-atoms of –OH group in glucose forms
hydrogen bonds with water molecules. Thus, glucose is soluble in water.
# Glycogen is a polymer of glucose. Because of numerous polar –OH groups exposed to the
surface, glycogen is also soluble in water.
# CO 2 is converted into H 2 CO 3 – both non-enzymatically as well as enzymatically in the
body fluid. The resultant carbonic acid and bicarbonate ions are highly soluble in water,
CO 2 (g) + H 2 O <-----> H 2 CO 3 (aq) <---------> H +
(aq) + HCO 3
-
(aq)
# Ca 2+
ions are highly soluble in water due to ionic interactions between Ca 2+
ions and water
molecules in the body fluid.
# Arginine is a basic amino acid, it has polar groups as well as positively charged side chain at
physiological pH. SO, it’s also soluble in the aqueous environment of the body fluid.
# Testosterone has a bulky, non-polar steroid nucleus, and is insoluble in body fluid or water.