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Which of the following is true about replication?
The lagging strand is synthesized in a continuous fashion and the leading strand is not
Helicase unwinds RNA
Primases lay down the primers on the lagging strand
Topoisomerase unwinds DNA
Solution
The only correct statement among the four in the given question is 'Topoisomerase unwinds
DNA'.
Explanation for others are; leading strand is synthesized in continuous fashion whereas lagging
strand is not, helicase unwinds DNA (which is double stranded) not the RNA (which is single
stranded), primases lay down the primers on both, the leading as well as the lagging strands.

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