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When to perform
Tricuspid valve
Surgery?
Julien Dreyfus MD and
David Messika-Zeitoun MD, PhD
Bichat Hospital, Paris, France
When to perform Tricuspid valve Surgery?
• A case by the ESC Working Group on Valvular Heart Disease
When to perform Tricuspid valve Surgery?
• 55 year old female

• No cardiovascular risk factors
• Rheumatic mitral stenosis
• In 2008 she underwent successful percutaneous mitral valve
commissurotomy
• Referred in 2013 with shortness of breath

• Physical examination
•
•
•
•
•

NYHA functional class III
Diastolic murmur at the apex
Systolic murmur increasing during inspiration
Right congestive heart failure
Atrial fibrillation
The Mitral Valve
Watch
video

Watch
video

Watch video

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Watch video

Mitral valve area =
1.3 cm²

Mean Gradient = 10 mm Hg
The Tricuspid Valve

Watch
video

Watch
video
What is you management strategy?

1.Repeat percutaneous mitral commissurotomy

2.Isolated mitral valve replacement

3.Combined
mitral
valve
replacement
tricuspid surgery (repair or replacement)

+

4.More
echocardiographic
needed

is

information
What is you management strategy?

1.Repeat percutaneous mitral commissurotomy

2.Isolated mitral valve replacement

3.Combined
mitral
valve
replacement
tricuspid surgery (repair or replacement)

+

4.More
echocardiographic
needed

is

information
What is you management ?

1.Repeat percutaneous mitral commissurotomy
One commissure is completely open and MR
grade is > 2 - mitral commissurotomy should
no be performed
2.Isolated mitral valve replacement Severe
tricuspid valve disease. Correction of leftsided disease does not cure the right side
3.Combined mitral valve replacement +
tricuspid surgery (repair or replacement)
4.More
echocardiographic
needed

information

is
Same patient but
different tricuspid
disease…
Watch video
What is you management strategy?

1.Repeat percutaneous mitral commissurotomy

2.Isolated mitral valve replacement

3.Combined
mitral
valve
replacement
tricuspid surgery (repair or replacement)

+

4.More
echocardiographic
needed

is

information
What is you management strategy?

1.Repeat percutaneous mitral commissurotomy

2.Isolated mitral valve replacement

3.Combined
mitral
valve
replacement
tricuspid surgery (repair or replacement)

+

4.More
echocardiographic
needed

is

information
Tricuspid annular
diameter
Limitations of surgical strategy based only on
degree of TR
1. After isolated mitral valve replacement, 30-50% of patients
develop moderate or severe late TR despite absent or mild
TR at baseline
Dreyfus G. Ann Thoarc Surg 2005; 79:127-132
Porter A. J Heart Valve Dis 1999; 8:57-62
Izumi C. J Heat Valve Dis 2002; 11:353-6

Predictive factors for the development of late severe TR
- Age
Ruel M. J Thorac Cardiovasc Surg 2004; 128:278-83
Song H. Circulation 2007; 116:I246-50
- Female gender
Kim HK. Circulation 2005; 112:I14-9
- Atrial fibrillation
Matsuyama. Ann Thorac Surg 2003; 75: 1826-8
Porter A. J Heart Valve Dis 1999; 8:57-62
- Pulmonary hypertension
Vincens JJ. Circulation 1995; 92:II 137-42
- Rheumatic disease
Levine MJ. Circulation 1989; 79:1061-7
Limitations of surgical strategy based only on
degree of TR
1. After isolated mitral valve replacement, 30-50% of patients
develop moderate or severe late TR despite absent or mild
TR at baseline
2. Occurrence of moderate / severe late TR is associated with
increased morbidity (congestive heart failure) and
mortality
Limits of a surgical strategy only based on TR
degree
1. After isolated mitral valve replacement, 30-50% of patients
develop moderate or severe late TR despite absent or mild
TR at baseline
2. Occurrence of moderate / severe late TR is associated with
increased morbidity (congestive heart failure) and
mortality
3. Surgery for isolated severe TR carries high morbidity and
high mortality
Limits of a surgical strategy only based on TR
degree
1. After isolated mitral valve replacement, 30-50% of patients
develop moderate or severe late TR despite absent or mild
TR at baseline
2. Occurrence of moderate / severe late TR is associated with
increased morbidity (congestive heart failure) and
mortality
3. Surgery for isolated severe TR carries high morbidity and
high mortality
Tricuspid annular diameter has been proposed as a more
sensitive parameter to guide surgical indications for
associated tricuspid valve surgery and to improve long-term
morbidity and mortality
Strategy based on annular diameter
• In 311 patients who underwent mitral valve repair a
tricuspid annuloplasty was performed only if the tricuspid
annular diameter measured during surgery was greater
than twice the normal size (> 70 mm) regardless of the
grade of regurgitation.

Anteroseptal
commissure

Dreyfus GD et al. Ann Thorac Surg 2005; 79:127-32

Anteroposterior
commissure
Strategy based on annular diameter
• In 311 patients who underwent mitral valve repair a
tricuspid annuloplasty was performed only if the tricuspid
annular diameter was greater than twice the normal size (>
70 mm) regardless of the grade of regurgitation.

• This strategy prevented the occurrence of
severe late TR and improved the functional
status
irrespective
of
the
grade
of
regurgitation.

Dreyfus GD et al. Ann Thorac Surg 2005; 79:127-32
Comparison of a strategy based on TR degree
alone OR TR degree and annular diameter
• First cohort:
2002-2004.
Associated TR
surgery if TR ≥
grade 3

• Second cohort:
2004-2006.
Associated TR
surgery if TR ≥
grade 3 OR
annular diameter
≥ 40 mm

Van de Veire NR. J Thorac Cardiovasc Surg 2011;141:1431-9
Comparison of a strategy based on TR degree
alone and TR degree and annular diameter

• A strategy based on TR degree and
tricuspid
annular
diameter
for
combined tricuspid valve surgery was
associated with the absence of
worsening of TR and the absence of
negative right ventricular remodelling
(enlargement)

Van de Veire NR. JTCVS J Thorac Cardiovasc Surg 2011;141:1431-9
Associated tricuspid annuloplasty
during mitral valve repair /
replacement should be
considered in patients with
tricuspid annular dilatation
despite the absence of significant
TR to prevent the occurrence of
right ventricular dysfunction and
advanced heart failure
TV annuloplasty adds little time
to the surgery and is associated
with very few complications
Guidelines on the management of valvular
heart disease (version 2012)

Vahanian et al. European Heart Journal 2012; 33(19):2451-2496
The best projection in which tricuspid annular diameter should be
assessed remains debated but measurements are usually performed in
the apical 4-chamber view.
TAKE HOME MESSAGES

• During left-sided valve surgery,
combined tricuspid valve surgery
(annuloplasty or replacement)
should be considered if TR grade
> 2/4 or tricuspid annular
diameter ≥ 40mm or ≥ 21mm/m²
of body surface area - especially if
predictors of occurrence of late TR
are present (age, female gender,
atrial fibrillation, pulmonary
hypertension or rheumatic
disease)
Join the ESC Working Group
on Valvular Heart Disease
and take part in its
activities !

Membership is FREE!

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When to perform Tricuspid valve Surgery?

  • 1. When to perform Tricuspid valve Surgery? Julien Dreyfus MD and David Messika-Zeitoun MD, PhD Bichat Hospital, Paris, France
  • 2. When to perform Tricuspid valve Surgery? • A case by the ESC Working Group on Valvular Heart Disease
  • 3. When to perform Tricuspid valve Surgery? • 55 year old female • No cardiovascular risk factors • Rheumatic mitral stenosis • In 2008 she underwent successful percutaneous mitral valve commissurotomy • Referred in 2013 with shortness of breath • Physical examination • • • • • NYHA functional class III Diastolic murmur at the apex Systolic murmur increasing during inspiration Right congestive heart failure Atrial fibrillation
  • 4. The Mitral Valve Watch video Watch video Watch video Watch video Watch video Mitral valve area = 1.3 cm² Mean Gradient = 10 mm Hg
  • 6. What is you management strategy? 1.Repeat percutaneous mitral commissurotomy 2.Isolated mitral valve replacement 3.Combined mitral valve replacement tricuspid surgery (repair or replacement) + 4.More echocardiographic needed is information
  • 7. What is you management strategy? 1.Repeat percutaneous mitral commissurotomy 2.Isolated mitral valve replacement 3.Combined mitral valve replacement tricuspid surgery (repair or replacement) + 4.More echocardiographic needed is information
  • 8. What is you management ? 1.Repeat percutaneous mitral commissurotomy One commissure is completely open and MR grade is > 2 - mitral commissurotomy should no be performed 2.Isolated mitral valve replacement Severe tricuspid valve disease. Correction of leftsided disease does not cure the right side 3.Combined mitral valve replacement + tricuspid surgery (repair or replacement) 4.More echocardiographic needed information is
  • 9. Same patient but different tricuspid disease… Watch video
  • 10. What is you management strategy? 1.Repeat percutaneous mitral commissurotomy 2.Isolated mitral valve replacement 3.Combined mitral valve replacement tricuspid surgery (repair or replacement) + 4.More echocardiographic needed is information
  • 11. What is you management strategy? 1.Repeat percutaneous mitral commissurotomy 2.Isolated mitral valve replacement 3.Combined mitral valve replacement tricuspid surgery (repair or replacement) + 4.More echocardiographic needed is information
  • 13. Limitations of surgical strategy based only on degree of TR 1. After isolated mitral valve replacement, 30-50% of patients develop moderate or severe late TR despite absent or mild TR at baseline Dreyfus G. Ann Thoarc Surg 2005; 79:127-132 Porter A. J Heart Valve Dis 1999; 8:57-62 Izumi C. J Heat Valve Dis 2002; 11:353-6 Predictive factors for the development of late severe TR - Age Ruel M. J Thorac Cardiovasc Surg 2004; 128:278-83 Song H. Circulation 2007; 116:I246-50 - Female gender Kim HK. Circulation 2005; 112:I14-9 - Atrial fibrillation Matsuyama. Ann Thorac Surg 2003; 75: 1826-8 Porter A. J Heart Valve Dis 1999; 8:57-62 - Pulmonary hypertension Vincens JJ. Circulation 1995; 92:II 137-42 - Rheumatic disease Levine MJ. Circulation 1989; 79:1061-7
  • 14. Limitations of surgical strategy based only on degree of TR 1. After isolated mitral valve replacement, 30-50% of patients develop moderate or severe late TR despite absent or mild TR at baseline 2. Occurrence of moderate / severe late TR is associated with increased morbidity (congestive heart failure) and mortality
  • 15. Limits of a surgical strategy only based on TR degree 1. After isolated mitral valve replacement, 30-50% of patients develop moderate or severe late TR despite absent or mild TR at baseline 2. Occurrence of moderate / severe late TR is associated with increased morbidity (congestive heart failure) and mortality 3. Surgery for isolated severe TR carries high morbidity and high mortality
  • 16. Limits of a surgical strategy only based on TR degree 1. After isolated mitral valve replacement, 30-50% of patients develop moderate or severe late TR despite absent or mild TR at baseline 2. Occurrence of moderate / severe late TR is associated with increased morbidity (congestive heart failure) and mortality 3. Surgery for isolated severe TR carries high morbidity and high mortality Tricuspid annular diameter has been proposed as a more sensitive parameter to guide surgical indications for associated tricuspid valve surgery and to improve long-term morbidity and mortality
  • 17. Strategy based on annular diameter • In 311 patients who underwent mitral valve repair a tricuspid annuloplasty was performed only if the tricuspid annular diameter measured during surgery was greater than twice the normal size (> 70 mm) regardless of the grade of regurgitation. Anteroseptal commissure Dreyfus GD et al. Ann Thorac Surg 2005; 79:127-32 Anteroposterior commissure
  • 18. Strategy based on annular diameter • In 311 patients who underwent mitral valve repair a tricuspid annuloplasty was performed only if the tricuspid annular diameter was greater than twice the normal size (> 70 mm) regardless of the grade of regurgitation. • This strategy prevented the occurrence of severe late TR and improved the functional status irrespective of the grade of regurgitation. Dreyfus GD et al. Ann Thorac Surg 2005; 79:127-32
  • 19. Comparison of a strategy based on TR degree alone OR TR degree and annular diameter • First cohort: 2002-2004. Associated TR surgery if TR ≥ grade 3 • Second cohort: 2004-2006. Associated TR surgery if TR ≥ grade 3 OR annular diameter ≥ 40 mm Van de Veire NR. J Thorac Cardiovasc Surg 2011;141:1431-9
  • 20. Comparison of a strategy based on TR degree alone and TR degree and annular diameter • A strategy based on TR degree and tricuspid annular diameter for combined tricuspid valve surgery was associated with the absence of worsening of TR and the absence of negative right ventricular remodelling (enlargement) Van de Veire NR. JTCVS J Thorac Cardiovasc Surg 2011;141:1431-9
  • 21. Associated tricuspid annuloplasty during mitral valve repair / replacement should be considered in patients with tricuspid annular dilatation despite the absence of significant TR to prevent the occurrence of right ventricular dysfunction and advanced heart failure TV annuloplasty adds little time to the surgery and is associated with very few complications
  • 22. Guidelines on the management of valvular heart disease (version 2012) Vahanian et al. European Heart Journal 2012; 33(19):2451-2496 The best projection in which tricuspid annular diameter should be assessed remains debated but measurements are usually performed in the apical 4-chamber view.
  • 23. TAKE HOME MESSAGES • During left-sided valve surgery, combined tricuspid valve surgery (annuloplasty or replacement) should be considered if TR grade > 2/4 or tricuspid annular diameter ≥ 40mm or ≥ 21mm/m² of body surface area - especially if predictors of occurrence of late TR are present (age, female gender, atrial fibrillation, pulmonary hypertension or rheumatic disease)
  • 24. Join the ESC Working Group on Valvular Heart Disease and take part in its activities ! Membership is FREE!