Cost of care according to disease-modifying therapy in Mexicans with relapsin...Erwin Chiquete, MD, PhD
Miguel A. Macı´as-Islas • Isaac F. Soria-Cedillo • Merced Velazquez-Quintana •
Victor M. Rivera • Vero´nica I. Baca-Muro • Edith A. Lemus-Carmona • Erwin Chiquete
Limited data exist on the costs of care of
patients with multiple sclerosis (MS) in low- to middleincome
nations. The purpose of this study was to describe
the economic burden associated with care of Mexican
patients with relapsing-remitting MS in a representative
sample of the largest institution of the Mexican public
healthcare system. We analysed individual data of 492
patients (67 % women) with relapsing-remitting MS registered
from January 2009 to February 2011 at the Mexican
Social Security Institute. Direct costs were measured about
the use of diagnostic tests, disease-modifying therapies
(DMTs), symptoms control, medical consultations,
relapses, intensive care and rehabilitation. Four groups
were defined according to DMT alternatives: (1) interferon
beta (IFNb)-1a, 6 million units (MU); (2) IFNb-1a, 12MU;
(3) IFNb-1b, 8MU; and (4) glatiramer acetate. All patients
received DMTs for at least 1 year. The most frequently
used DMT was glatiramer acetate (45.5 %), followed by
IFNb-1a 12MU (22.6 %), IFNb-1b 8MU (20.7 %), and
IFNb-1a 6MU (11.2 %). The mean cost of a specialised
medical consultation was €74.90 (US $107.00). A single
relapse had a mean total cost of €2,505.97 (US $3,579.96).
No differences were found in annualised relapse rates and
costs of relapses according to DMT. However, a significant
difference was observed in total annual costs according to
treatment groups (glatiramer acetate being the most
expensive), mainly due to differences in unitary costs of
alternatives. From the public institutional perspective,
when equipotent DMTs are used in patients with comparable
characteristics, the costs of DMTs largely determine
the total expenses associated with care of patients with
relapsing-remitting MS in a middle-income country.
Cost of care according to disease-modifying therapy in Mexicans with relapsin...Erwin Chiquete, MD, PhD
Miguel A. Macı´as-Islas • Isaac F. Soria-Cedillo • Merced Velazquez-Quintana •
Victor M. Rivera • Vero´nica I. Baca-Muro • Edith A. Lemus-Carmona • Erwin Chiquete
Limited data exist on the costs of care of
patients with multiple sclerosis (MS) in low- to middleincome
nations. The purpose of this study was to describe
the economic burden associated with care of Mexican
patients with relapsing-remitting MS in a representative
sample of the largest institution of the Mexican public
healthcare system. We analysed individual data of 492
patients (67 % women) with relapsing-remitting MS registered
from January 2009 to February 2011 at the Mexican
Social Security Institute. Direct costs were measured about
the use of diagnostic tests, disease-modifying therapies
(DMTs), symptoms control, medical consultations,
relapses, intensive care and rehabilitation. Four groups
were defined according to DMT alternatives: (1) interferon
beta (IFNb)-1a, 6 million units (MU); (2) IFNb-1a, 12MU;
(3) IFNb-1b, 8MU; and (4) glatiramer acetate. All patients
received DMTs for at least 1 year. The most frequently
used DMT was glatiramer acetate (45.5 %), followed by
IFNb-1a 12MU (22.6 %), IFNb-1b 8MU (20.7 %), and
IFNb-1a 6MU (11.2 %). The mean cost of a specialised
medical consultation was €74.90 (US $107.00). A single
relapse had a mean total cost of €2,505.97 (US $3,579.96).
No differences were found in annualised relapse rates and
costs of relapses according to DMT. However, a significant
difference was observed in total annual costs according to
treatment groups (glatiramer acetate being the most
expensive), mainly due to differences in unitary costs of
alternatives. From the public institutional perspective,
when equipotent DMTs are used in patients with comparable
characteristics, the costs of DMTs largely determine
the total expenses associated with care of patients with
relapsing-remitting MS in a middle-income country.
The Essentia is an exclusive collection of properties gathered around a spacious open green private space, overlooking open sky in front as there are no high-rise buildings opposite the complex.
Confira na íntegra a decisão que afastou Eduardo Cunha da CâmaraMaria Santos
O ministro do STF Teori Zavascki determinou nesta quinta-feira o afastamento do presidente da Câmara Eduardo Cunha (PMDB-RJ) não apenas do comando da Câmara, mas também do mandato de deputado federal. O político foi transformado em réu no STF por unanimidade. Cunha é acusado pelos crimes de lavagem de dinheiro e corrupção, por supostamente integrar o esquema de propinas distribuídas na Petrobras. O peemedebista teria recebido US$ 5 milhões da estatal. O político tem o mandato de deputado suspenso e fica fora da linha sucessória da presidência, mas ainda mantém o foro no STF.
Реализация информационных проектов в рамках сотрудничества вузов и органов вл...prasu1995
Авторы: Комиссарова Л.М., Макарова Е.В., Сидорова А.Г.
Статья опубликована в сборнике:
PR в изменяющемся мире: Региональный аспект: сборник статей/ под ред. М.В. Гундарина, А. Г. Сидоровой, Ю. В. Явинской. – Вып. 9. – Барнаул: Изд-во Алт. ун-та, 2011.
Hoje, ser só competente não basta, as empresas estão buscando profissionais megacompetentes. Que transformam problemas em soluções e adversidade em oportunidade. As equipes não podem ser mais ou menos competentes, têm que ser extraordinárias.
The Essentia is an exclusive collection of properties gathered around a spacious open green private space, overlooking open sky in front as there are no high-rise buildings opposite the complex.
Confira na íntegra a decisão que afastou Eduardo Cunha da CâmaraMaria Santos
O ministro do STF Teori Zavascki determinou nesta quinta-feira o afastamento do presidente da Câmara Eduardo Cunha (PMDB-RJ) não apenas do comando da Câmara, mas também do mandato de deputado federal. O político foi transformado em réu no STF por unanimidade. Cunha é acusado pelos crimes de lavagem de dinheiro e corrupção, por supostamente integrar o esquema de propinas distribuídas na Petrobras. O peemedebista teria recebido US$ 5 milhões da estatal. O político tem o mandato de deputado suspenso e fica fora da linha sucessória da presidência, mas ainda mantém o foro no STF.
Реализация информационных проектов в рамках сотрудничества вузов и органов вл...prasu1995
Авторы: Комиссарова Л.М., Макарова Е.В., Сидорова А.Г.
Статья опубликована в сборнике:
PR в изменяющемся мире: Региональный аспект: сборник статей/ под ред. М.В. Гундарина, А. Г. Сидоровой, Ю. В. Явинской. – Вып. 9. – Барнаул: Изд-во Алт. ун-та, 2011.
Hoje, ser só competente não basta, as empresas estão buscando profissionais megacompetentes. Que transformam problemas em soluções e adversidade em oportunidade. As equipes não podem ser mais ou menos competentes, têm que ser extraordinárias.
