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VieCell
Biotech
VieCell Biotech is a contemporary biotech
company committed in the development of novel cell
therapeutics derived from blood and various fetal
tissues. Our research and development team pursues
cutting edge research in regenerative application of
stem cells from various sources and provides a
complete solution to diseases which are not able to
cure by conventional treatments. Our broad area of
expertise includes providing leading technology in
bringing unique therapy, aesthetic and anti-ageing
cosmetics applications. Considering regenerative
medicine is the only potential alternative of the future,
we here in VieCell continuously committed in bringing
full proof technology for the same.
Focusing on
VieCell approach for ailments is a multi-centric
application by combining traditional medicine with
modern regenerative medicine.
VieCell is committed in bringing unique and innovative
therapeutic stem cell solutions for vary rare and
incurable diseases through intensive clinical research.
Our competent R&D team is developing for novel stem
celltechnologies to pipeline robust next generation
products.
Our fundamental grail is to provide medical service in a
safe, caring and affordable ways without compromising
the quality of the treatment.
Regeneration Through Stem Cells
MESENCHYMAL STEM CELLS (MSCs)
Stem cells are undifferentiated biological cells that can differentiate
into specialized cells
 First isolated by Friedenstein et al in 1974
 Fibroblastoid cells - spindle-shaped
 Adherent to tissue culture glass or plastic
 High growth potential
Sources for Stem cells
Φ Bone marrow
Φ Umbilical cord tissue and blood
Φ Peripheral blood
Φ Placenta
Φ Adipose
Φ Dental pulp
Φ Amniotic
• The body is made up of about 200 different kinds of
specialised cells such as muscle cells, nerve cells, fat cells
and skin cells
• All cells in the body come from stem cells
• A stem cell is a cell that is not yet specialised
• The process of specialisation is called differentiation
TYPES OF STEM CELLS
Mesenchymal stem cells
/Adult stem cells (MSC)
Embryonic stem cells (ESC)
Induced Pluripotent Stem Cells (iPSC)
MESENCHYMAL STEM CELLS POTENTIALITIES
MECHANISM OF ACTION OF MSCS
MIGRATION OF MSCs TO THE SITE OF INJURY
*Malaysian J Pathol 2013 35, 1 : 17 – 32
DISEASES TREATABLE WITH MSCs
• Osteoarthritis
• Avascular Necrosis (AVN)
• Tendinitis
• Ankylosing Spondylitis
• Rheumatoid Arthritis
• Sports Injuries
• Osteoporosis
• Autism
• DMD
• Multiple sclerosis
• Epilepsy
• Spinal cord Injury
• Ataxia
• Motor neuron diseases
• Cerebral palsy
• Parkinson
• Alzheimer’s
• Neuropathy
• Spinal Muscular Atrophy
• Scleroderma
• Myasthenia gravis
• Diabetes Type I
• Diabetes Type II
• Diabetic Foot Ulcer
• Diabetic Neuropathy
• Diabetic Retinopathy
Orthopaedic
Third Title
• Cardiovascular
• Stroke
• Liver-COPD, Liver Cirrhosis
• Kidney- Kidney Failure
• Erectile Dysfunction
• Endometrium thickening
Metabolic Disorders Neurological Conditions
Organ Related Impotence
• Chris Hyunchul Jo, et. al., Intra-articular injection of mesenchymal stem cells for the
treatment of Osteoarthritis of the knee: A Proof-of-concept clinical trial. (2014), Stem
Cells;32:1254-1266.
Osteoarthritis
• Peter Connick, et. al., Autologous mesenchymal stem cells for the treatment of secondary
progressive multiple sclerosis: an open-label phase 2a proof-of-concept study. (2012), Lancet
Neurol; 11: 150–56.
Multiple Sclerosis
• Alok Sharma, et. al., Autologous Bone Marrow Mononuclear Cell Therapy for Autism: An Open
Label Proof of Concept Study. (2013), Stem Cells International; Article ID 623875, 13Pages.
Autism
• Yun-An Tsai, et. al., Treatment of Spinocerebellar Ataxia With Mesenchymal Stem Cells: A
Phase I/IIa Clinical Study. (2017), Cell Transplantation, Vol. 26, pp. 503–512.
Ataxia
• Liya Lin, et. al., Bone marrow mesenchymal stem cells (BMSCs) improved functional
recovery of spinal cord injury partly by promoting axonal regeneration. (2018). Neurochemistry
International, 115,80-84.
Spinal Cord Injury
PUBLICATIONS SUPPORTING STEM CELL THERAPY
• Julien Freitag, et. al., Effect of autologous adipose-derived mesenchymal stem cell therapy
in the treatment of a post-traumatic chondral defect of the knee. (2017), BMJ Case Rep.2017;
1-8
Sports Injury
PUBLICATIONS SUPPORTING STEM CELL THERAPY
• Jianxia Hu, et. al., Long term effects of the implantation of Wharton’s jelly-derived mesenchymal
stem cells from the umbilical cord for newly-onset type 1 diabetes mellitus. (2013), Endocrine
Journal; 60 (3), 347-357.
Diabetes Type I
• Liu, et al., A preliminary evaluation of efficacy and safety of Wharton’s jelly mesenchymal stem
cell transplantation in patients with type 2 diabetes mellitus. (2014), Stem Cell Research &
Therapy, 5:57.
Diabetes Type II
S. Kirana, et. al., Autologous stem cell therapy in the treatment of limb ischaemia induced
chronic tissue ulcers of diabetic foot patients. (2012), Int J Clin Pract,66, 4, 384–393
Diabetic Foot Ulcer
• Sibel Çağlar Okur, et. al., The Effect of Umbilical Cord-derived Mesenchymal Stem Cell
Transplantation in a Patient with Cerebral Palsy: A Case Report. (2018), Int J Stem Cells.; 11(1):
141–147.
Cerebral Palsy
• Hlebokazov F., Treatment of refractory epilepsy patients with autologous mesenchymal stem
cells reduces seizure frequency: An open label study. (2017), Adv Med Sci.;62(2):273-279.
Epilepsy
The hope for millions of patients
lies in the advancement of
Stem Cell Technology
And the realization of this hope
is tied deeply into the efforts of
VieCell Biotech

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VieCell Biotech

  • 1. VieCell Biotech VieCell Biotech is a contemporary biotech company committed in the development of novel cell therapeutics derived from blood and various fetal tissues. Our research and development team pursues cutting edge research in regenerative application of stem cells from various sources and provides a complete solution to diseases which are not able to cure by conventional treatments. Our broad area of expertise includes providing leading technology in bringing unique therapy, aesthetic and anti-ageing cosmetics applications. Considering regenerative medicine is the only potential alternative of the future, we here in VieCell continuously committed in bringing full proof technology for the same. Focusing on VieCell approach for ailments is a multi-centric application by combining traditional medicine with modern regenerative medicine. VieCell is committed in bringing unique and innovative therapeutic stem cell solutions for vary rare and incurable diseases through intensive clinical research. Our competent R&D team is developing for novel stem celltechnologies to pipeline robust next generation products. Our fundamental grail is to provide medical service in a safe, caring and affordable ways without compromising the quality of the treatment. Regeneration Through Stem Cells
  • 2.
  • 3. MESENCHYMAL STEM CELLS (MSCs) Stem cells are undifferentiated biological cells that can differentiate into specialized cells  First isolated by Friedenstein et al in 1974  Fibroblastoid cells - spindle-shaped  Adherent to tissue culture glass or plastic  High growth potential Sources for Stem cells Φ Bone marrow Φ Umbilical cord tissue and blood Φ Peripheral blood Φ Placenta Φ Adipose Φ Dental pulp Φ Amniotic
  • 4. • The body is made up of about 200 different kinds of specialised cells such as muscle cells, nerve cells, fat cells and skin cells • All cells in the body come from stem cells • A stem cell is a cell that is not yet specialised • The process of specialisation is called differentiation
  • 5. TYPES OF STEM CELLS Mesenchymal stem cells /Adult stem cells (MSC) Embryonic stem cells (ESC) Induced Pluripotent Stem Cells (iPSC)
  • 6. MESENCHYMAL STEM CELLS POTENTIALITIES
  • 8. MIGRATION OF MSCs TO THE SITE OF INJURY *Malaysian J Pathol 2013 35, 1 : 17 – 32
  • 9. DISEASES TREATABLE WITH MSCs • Osteoarthritis • Avascular Necrosis (AVN) • Tendinitis • Ankylosing Spondylitis • Rheumatoid Arthritis • Sports Injuries • Osteoporosis • Autism • DMD • Multiple sclerosis • Epilepsy • Spinal cord Injury • Ataxia • Motor neuron diseases • Cerebral palsy • Parkinson • Alzheimer’s • Neuropathy • Spinal Muscular Atrophy • Scleroderma • Myasthenia gravis • Diabetes Type I • Diabetes Type II • Diabetic Foot Ulcer • Diabetic Neuropathy • Diabetic Retinopathy Orthopaedic Third Title • Cardiovascular • Stroke • Liver-COPD, Liver Cirrhosis • Kidney- Kidney Failure • Erectile Dysfunction • Endometrium thickening Metabolic Disorders Neurological Conditions Organ Related Impotence
  • 10. • Chris Hyunchul Jo, et. al., Intra-articular injection of mesenchymal stem cells for the treatment of Osteoarthritis of the knee: A Proof-of-concept clinical trial. (2014), Stem Cells;32:1254-1266. Osteoarthritis • Peter Connick, et. al., Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study. (2012), Lancet Neurol; 11: 150–56. Multiple Sclerosis • Alok Sharma, et. al., Autologous Bone Marrow Mononuclear Cell Therapy for Autism: An Open Label Proof of Concept Study. (2013), Stem Cells International; Article ID 623875, 13Pages. Autism • Yun-An Tsai, et. al., Treatment of Spinocerebellar Ataxia With Mesenchymal Stem Cells: A Phase I/IIa Clinical Study. (2017), Cell Transplantation, Vol. 26, pp. 503–512. Ataxia • Liya Lin, et. al., Bone marrow mesenchymal stem cells (BMSCs) improved functional recovery of spinal cord injury partly by promoting axonal regeneration. (2018). Neurochemistry International, 115,80-84. Spinal Cord Injury PUBLICATIONS SUPPORTING STEM CELL THERAPY • Julien Freitag, et. al., Effect of autologous adipose-derived mesenchymal stem cell therapy in the treatment of a post-traumatic chondral defect of the knee. (2017), BMJ Case Rep.2017; 1-8 Sports Injury
  • 11. PUBLICATIONS SUPPORTING STEM CELL THERAPY • Jianxia Hu, et. al., Long term effects of the implantation of Wharton’s jelly-derived mesenchymal stem cells from the umbilical cord for newly-onset type 1 diabetes mellitus. (2013), Endocrine Journal; 60 (3), 347-357. Diabetes Type I • Liu, et al., A preliminary evaluation of efficacy and safety of Wharton’s jelly mesenchymal stem cell transplantation in patients with type 2 diabetes mellitus. (2014), Stem Cell Research & Therapy, 5:57. Diabetes Type II S. Kirana, et. al., Autologous stem cell therapy in the treatment of limb ischaemia induced chronic tissue ulcers of diabetic foot patients. (2012), Int J Clin Pract,66, 4, 384–393 Diabetic Foot Ulcer • Sibel Çağlar Okur, et. al., The Effect of Umbilical Cord-derived Mesenchymal Stem Cell Transplantation in a Patient with Cerebral Palsy: A Case Report. (2018), Int J Stem Cells.; 11(1): 141–147. Cerebral Palsy • Hlebokazov F., Treatment of refractory epilepsy patients with autologous mesenchymal stem cells reduces seizure frequency: An open label study. (2017), Adv Med Sci.;62(2):273-279. Epilepsy
  • 12. The hope for millions of patients lies in the advancement of Stem Cell Technology And the realization of this hope is tied deeply into the efforts of VieCell Biotech

Editor's Notes

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  2. <number> Stem cell are..…….specialized cells.
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