The video shows the band Muse performing their song "Uprising" while riding on a pickup truck through a model city at night. Teddy bears later terrorize the city but are defeated by fire. The darkly-lit video portrays the band's rebellious image against being controlled. It targets audiences aged 13-35 through its rock genre and lyrics about protest. Visuals of the band in the small-scale city represent their lower power facing opposition from the larger teddy bears.