This document discusses creating a digital edition of letters written by Vespasiano da Bisticci, an 15th century Florentine copyist, as linked open data. It describes annotating the letters with embedded XML/TEI markup linking to RDF files about persons, manuscripts, and terms. Relationships between these entities are represented in the RDF files to create a knowledge base. The goal is to expose the letters and associated data as linked open data using domain ontologies and existing datasets to weave the information into the larger web of data.