Vert.x is an asynchronous application platform that runs on the JVM and supports multiple programming languages. It uses an event-driven, non-blocking model where event handlers are used to avoid blocking threads. Verticles are deployed units that isolate classloading and contain event loops with event handlers. The event bus allows asynchronous messaging between verticles on the same or different machines. Worker verticles can be used to handle blocking operations so as not to block the event loop.