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Conversational interfaces for
                        clinical information systems




                                                                     January 2011
                                                   VAL9000, Inc.
                                       SM
Simplifying the practice of medicine               Richard Koffler
                                                   rk@val9000.com
                                                   (310) 807-5786

                                                   Dr. Val Nenov
                                                   val@val9000.com
                                                                       1
                                                   January 2011
Five keys to doctor-friendly
electronic medical records
1.   Intuitive, unobtrusive, easy,
     without training hassles

2.   Quick: In, out, done!

3.   Accessible everywhere:
     At point of care, on the
     road, between offices, at
     home, etc.

4.   Available immediately
                                     Is this a productive use




                                                                January 2011
     when needed, no delays
                                      of the doctor’s time?
5.   Always accurate: No
     follow-up human proofing

     Anything else is
     unproductive, and takes                                      2
     time from seeing patients
     and practicing medicine
Mobile apps nice but very imperfect

              Low-productivity user interfaces
              • Cramped screens; cumbersome to navigate, find, retrieve
                       Click-swipe-type-click-swipe-click-swipe-…
              • Every app behaves differently, training headaches
              • User can’t multitask: Distractive to use while doing other things




              One more thing to carry
              • Cramped-screen smartphones fit in pocket, but tablets don’t
              • Prone to forgetting, losing, dropping in sink, etc.
              • And useless when battery dies




                                                                                    January 2011
              Endless chasing after platform obsolescence
              • Explosion of operating systems, hardware, apps, etc.
              • Impossible to get all doctors and nurses to carry the same device
                                                                                      3
Our piece of the solution


                                            EMR
                                            HIS
                                            PHR
                                            etc.




                                                   January 2011
       No apps. No keyboards. No screens.
         Just pick up any phone and talk.
                                                     4
           From anywhere at any time.
For example

          Anything need my attention?                              Real-time
                                                                   data exchange

                      Mary Smith presents headaches

                What are her vitals?
                                                                  Nursing
                                                               documentation
                      BP 140 over 95. Temp 101. RR 22.            system

                                                              Bedside monitor
              Order an MRI of the brain
                                                                  Radiology
                                                                 information
                       Patient had a CT of the brain in




                                                                                   January 2011
                                                                   system
                           May. Proceed anyway?
                                                               Personal health
                        Yes                                        records

                                                              Insurance records
                     Patient is allergic to ionic contrast.
                     Non-ionic requires authorization.         Care protocols        5
                              Proceed anyway?
Conversation snippets
    Patient follow-up

    • MD             What patients require my immediate attention?
    • VAL 9000       John Doe, 55, stroke patient, room 1413, …
    • MD             Do you have his latest test results?
    • VAL 9000       Yes, except for radiology. Would you like to order an MRI?
    • MD             No, thanks. Order full blood test and consultation with neurology
    • VAL 9000       Would you like me to notify you when the results are available?
    • MD             Yes please

    Order tests

    • MD             Order an MR of the brain
    • VAL 9000       With contrast?




                                                                                         January 2011
    • MD             Yes
    • VAL 9000       Patient appears to be allergic. Non-ionic contrast requires
                     insurance authorization. Do you want to order contrast anyway?

    Review results

    • MD             When was last blood test and what was abnormal?
    • VAL 9000       July 21 8am non-HDL C was 145, normal is 50 to 130                    6
Conversation snippets
    Prescribe meds

    • MD             Prescribe Zocor 20 milligrams
    • VAL 9000       May I substitute with generic simvastatin?
    • MD             Yes, go ahead

    Dictate notes

    • MD             Dictate note
    • VAL 9000       Ready for dictation
    • MD             Patient presented with severe abdominal pain…

    Schedule consults

    • MD             Order infectious-disease consult




                                                                                 January 2011
    • VAL 9000       Done. Want to add notes or instructions?
    • MD             Yes. Patient presented with abdominal pain…

    Collaborate with other doctors, nurses, assistants

    • VAL 9000       You have a message from Dr Brown
    • MD             What is it?                                                   7
    • VAL 9000       Hi. I examined patient for a possible infectious disease…
Why voice?

             No special training:
             Users already know how to talk “medical”



             Quick, targeted data access:
             No click-click-type-click-click-swipe-type-type…



             Ubiquitous: Phones everywhere,




                                                                January 2011
             but keyboards & screens not always available



             Multi-tasking: Use while giving care, walking,
             driving, operating, etc.                             8
VAL9000’s key features

               Complements existing clinical information systems
               • Spoken conversations replace keyboards and displays
               • Doesn’t store data: Retrieves from and saves to existing systems
                 •Knows which systems to read from and write to
               • Tasks: Timely & complete charting, submission of care plans, order
                 entry, e-prescribing, insurance approvals, workflows, alarms, alerts, etc.


               Natural to use, quick, accurate, unobtrusive, polite
               • Eliminates burden of learning multiple clinical systems: just ask
               • Plain English: Speak normally, no training needed
                 •Understands meaning, intent, jargon, acronyms, abbreviations, etc.
                 •Handles accents, enunciation, pronunciation, etc.




                                                                                              January 2011
               • Anticipates requests and suggests actions


               Conveniently ubiquitous and secure
               • Just pick up any phone & talk anywhere any time
               • 100% voice driven using any phone: Landline, cell, VoIP, SIP                   9
               • No keyboards, displays, mobile apps
               • Server-based intrinsically secure: Like two people having a conversation
How is VAL9000 different from Nuance Dragon Solutions

  NUANCE’s goal:
  Produce text documents

  • Action: Dictate instead of typing    • One-way speech-
                                           to-text dictation
    • Limited to one-way task of         • Requires human
      dictating text reports               proofing for 100%
                                           accuracy
    • Doesn’t:
      • Handle clinical workflows
      • Retrieve data
      • Save structured data




                                                                                        January 2011
  • Primary metric: Speech-recognition
    accuracy ‒ and still needs human
    proofing
  • Requires software on computer or
    mobile + high-quality microphones
                                                                                        10
                                                      • Offline (not real-time) tools
                                                        to extract some structured
                                                        data from text reports
How is VAL9000 different from Nuance Dragon Solutions

  VAL9000’s goal:
  Simplify practice of medicine


  • Action: Workflow optimization with           • Two-way spoken
                                                   conversations:
    two-way spoken interactions with               find & save
    clinical information systems                   structured data

   • Replace keyboards & displays with           • Self-proofing
                                                   throughout
     speech recognition + artificial               conversations
     intelligence + clinical workflows
                                                              SYMPTOM CONSTIPATION




                                           CLINICAL SYSTEMS
   • Finds & saves structured clinical                        SYMPTOM NO DIARRHEA
     data: results, notes, orders, etc.                       ON MEDICATION MONOPRIL 10MG




                                                                                                 January 2011
   • Automatically assembles text                             FAMILY HISTORY DIABETES MELLITUS
     documents from structured data                           INTAKE BP 112 70
                                                              INTAKE RR 18
   • Manages alarms, alerts, follow-ups
  • Primary metric: Correctly understand
    and respond to user’s intent
                                                 • Automatic                                     11
  • No equipment or installable software           report creation
    needed: Call & talk from any phone             only when
                                                   needed
It’s working at

     Four piloted applications since 2006

     • Bedside data capture
     • Verbal order entry
     • Care-coordination and patient rounds phone service
     • Assets & personnel tracking via hospital-wide WiFi network


     Eight system interfaces

     • Radiology, oncology, pathology, lab, pharmacy (HL7, SOAP)




                                                                    January 2011
     • Bedside monitors (Unity Network)
     • Nursing documentation system (Essentris, Clinicomp)
     • Cisco Wireless Location Manager


                                                                    12
Benefits: Efficient, convenient, immediate turnaround

    Productive on-the-go data retrieval and entry

    • No paper charts or click-click-type-click-type-type-click-click…
    • No paper scribbling or remembering for later:
      Immediate entry of care plans, orders, Rx
    • Real-time compliance with workflow & care protocols


    Collaboration among providers (and patients)

    • Communication “through medical record” instead of interruptive
      phone calls, voicemail, “phone tag”




                                                                         January 2011
    Less time learning new systems



                                                                         13
ROI: Hard-dollar savings
Gives MD’s and RN’s more time to see patients

Eliminates or reduces data-entry clerks and scribes

Reduces need for multi-system portals, mobile apps

SaaS: No CapX or added infrastructure

Helps comply with meaningful-use requirements

Keeps logs for productivity & efficiency assessment




                                                      January 2011
                                                      14
System architecture




                                                                                              EMR
                                                                                              HIS
                                                        RULES
                                                       ENGINE                                 PHR
               •   ASR                                                   • HL7
               •   NLP (CLP)                •   User profiles            • Web services       UCS
               •   TTS                      •   Workflows                • Custom
               •   Telephony                •   Templates                                     etc.
                                            •   Care protocols
                                            •   Alerts
                     CONVERSATION                                            DATA INTERFACE




                                                                                                     January 2011
                        ENGINE                                                  ENGINE




           •       Uses off-the-shelf speech-recognition and speech-synthesis components
           •       Artificial-intelligence technology incorporated in all engines                    15
           •       HIPAA compliance shared by all engines
System interfaces

    Interoperates using standard interface protocols

    • HL7
    • Web services
    • Custom

    Interoperates with multiple systems

    • Automatically routes data to/from data repositories (e.g., EMR, RIS,
      HIS, LIS) and real-time devices (e.g., bedside monitors)




                                                                             January 2011
                                                                             16
Voice user interface

    “Free form”, natural conversations

    • Users speak as they always do: No retraining required
      • Automatically handles accents, enunciation, pronunciation, etc.
    • Understands meaning, intent, jargon, acronyms, abbreviations, etc.
    • Verbal algebra, unit conversions, clinical calculators, date algebra

    Adaptable “verbosity” and hand-holding

    • Smart, silent, audio, verbose

    Multiple languages




                                                                             January 2011
    • Could understand 4 (EN, ES, FR, DE); speaks 7 (+ CN, IT, JP)

    User identification and authentication

    • Voice-print, name & PIN, caller ID                                     17
Frictionless implementation



                         We take care
                         of the rest
                         • Rules & profiles
                         • Data-exchange
Customer selects           interfaces             When ready, customer
initial application(s)   • Telephony interfaces   adds applications
                         • Test and tweak
                         • Go live
                         • Analyze, tweak,
                           optimize




                                                                         January 2011
                                                                         18
Price
Hosted, in the cloud = No CapX or additional IT infrastructure


Implementation fee + three SaaS options


                    Per session         Per port         Per minute

                   • Cents to        • $100 to         • 10¢ ‒ 20¢
                     dollars           $1000             per minute
                     per session       per month




                                                                      January 2011
                                                                      19
MedVox: Consumer version of VAL 9000


                      Patients




 Emergency
                                         Caregivers
 room staff
                      SECURE
                     ACCESS OF
                     PERSONAL
                      HEALTH
                     RECORDS




                                                      January 2011
         Emergency
                                 Doctors &
          response
                                  nurses
           medics




                                                      20
Three to five years from now


                     Smarter rules,
                                                    More medical
                      workflows,
                                                    applications
                      templates




                                                                    Deeper real-time
 More intelligent,
                                                                     integration with
    versatile
                                                                   clinical information
  conversations
                                                                          systems
                                      INTELLIGENT
                                        MEDICAL




                                                                                          January 2011
                                       ASSISTANTS




                                                                                          21
About us

• Computer science                   • Inventor: VAL 9000
  (MS UC Berkeley, BS MIT)
                                     • Micro-electronics
• Career launching and growing IT      (MS Prague Polytechnic),
  startups                             computer science, neuroscience
                                       (PhDs UCLA)
 • Co-founder of highly successful
   healthcare IT & telemedicine      • Research: clinical information
   venture                             systems, clinical trials, neural
                                       networks, artificial intelligence,
                                       natural language processing
                                     • Founder and CTO of highly
                                       successful provider of EMR portals
                                       on handheld devices




                                                                            January 2011
Richard Koffler                      Dr. Val Nenov
CEO                                  CTO

                                                                            22
Conversational interfaces for
                     clinical information systems


                                       SM
                                                     VAL9000, Inc.
Simplifying the practice of medicine
                                                     Richard Koffler




                                                                       January 2011
                                                     rk@val9000.com
                                                     (310) 807-5786
                                                     Dr. Val Nenov
                                                     val@val9000.com
                                                                       23
                                                     January 2011

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Val9000 Conversational Interfaces for Clinical Information Systems

  • 1. Conversational interfaces for clinical information systems January 2011 VAL9000, Inc. SM Simplifying the practice of medicine Richard Koffler rk@val9000.com (310) 807-5786 Dr. Val Nenov val@val9000.com 1 January 2011
  • 2. Five keys to doctor-friendly electronic medical records 1. Intuitive, unobtrusive, easy, without training hassles 2. Quick: In, out, done! 3. Accessible everywhere: At point of care, on the road, between offices, at home, etc. 4. Available immediately Is this a productive use January 2011 when needed, no delays of the doctor’s time? 5. Always accurate: No follow-up human proofing Anything else is unproductive, and takes 2 time from seeing patients and practicing medicine
  • 3. Mobile apps nice but very imperfect Low-productivity user interfaces • Cramped screens; cumbersome to navigate, find, retrieve Click-swipe-type-click-swipe-click-swipe-… • Every app behaves differently, training headaches • User can’t multitask: Distractive to use while doing other things One more thing to carry • Cramped-screen smartphones fit in pocket, but tablets don’t • Prone to forgetting, losing, dropping in sink, etc. • And useless when battery dies January 2011 Endless chasing after platform obsolescence • Explosion of operating systems, hardware, apps, etc. • Impossible to get all doctors and nurses to carry the same device 3
  • 4. Our piece of the solution EMR HIS PHR etc. January 2011 No apps. No keyboards. No screens. Just pick up any phone and talk. 4 From anywhere at any time.
  • 5. For example Anything need my attention? Real-time data exchange Mary Smith presents headaches What are her vitals? Nursing documentation BP 140 over 95. Temp 101. RR 22. system Bedside monitor Order an MRI of the brain Radiology information Patient had a CT of the brain in January 2011 system May. Proceed anyway? Personal health Yes records Insurance records Patient is allergic to ionic contrast. Non-ionic requires authorization. Care protocols 5 Proceed anyway?
  • 6. Conversation snippets Patient follow-up • MD What patients require my immediate attention? • VAL 9000 John Doe, 55, stroke patient, room 1413, … • MD Do you have his latest test results? • VAL 9000 Yes, except for radiology. Would you like to order an MRI? • MD No, thanks. Order full blood test and consultation with neurology • VAL 9000 Would you like me to notify you when the results are available? • MD Yes please Order tests • MD Order an MR of the brain • VAL 9000 With contrast? January 2011 • MD Yes • VAL 9000 Patient appears to be allergic. Non-ionic contrast requires insurance authorization. Do you want to order contrast anyway? Review results • MD When was last blood test and what was abnormal? • VAL 9000 July 21 8am non-HDL C was 145, normal is 50 to 130 6
  • 7. Conversation snippets Prescribe meds • MD Prescribe Zocor 20 milligrams • VAL 9000 May I substitute with generic simvastatin? • MD Yes, go ahead Dictate notes • MD Dictate note • VAL 9000 Ready for dictation • MD Patient presented with severe abdominal pain… Schedule consults • MD Order infectious-disease consult January 2011 • VAL 9000 Done. Want to add notes or instructions? • MD Yes. Patient presented with abdominal pain… Collaborate with other doctors, nurses, assistants • VAL 9000 You have a message from Dr Brown • MD What is it? 7 • VAL 9000 Hi. I examined patient for a possible infectious disease…
  • 8. Why voice? No special training: Users already know how to talk “medical” Quick, targeted data access: No click-click-type-click-click-swipe-type-type… Ubiquitous: Phones everywhere, January 2011 but keyboards & screens not always available Multi-tasking: Use while giving care, walking, driving, operating, etc. 8
  • 9. VAL9000’s key features Complements existing clinical information systems • Spoken conversations replace keyboards and displays • Doesn’t store data: Retrieves from and saves to existing systems •Knows which systems to read from and write to • Tasks: Timely & complete charting, submission of care plans, order entry, e-prescribing, insurance approvals, workflows, alarms, alerts, etc. Natural to use, quick, accurate, unobtrusive, polite • Eliminates burden of learning multiple clinical systems: just ask • Plain English: Speak normally, no training needed •Understands meaning, intent, jargon, acronyms, abbreviations, etc. •Handles accents, enunciation, pronunciation, etc. January 2011 • Anticipates requests and suggests actions Conveniently ubiquitous and secure • Just pick up any phone & talk anywhere any time • 100% voice driven using any phone: Landline, cell, VoIP, SIP 9 • No keyboards, displays, mobile apps • Server-based intrinsically secure: Like two people having a conversation
  • 10. How is VAL9000 different from Nuance Dragon Solutions NUANCE’s goal: Produce text documents • Action: Dictate instead of typing • One-way speech- to-text dictation • Limited to one-way task of • Requires human dictating text reports proofing for 100% accuracy • Doesn’t: • Handle clinical workflows • Retrieve data • Save structured data January 2011 • Primary metric: Speech-recognition accuracy ‒ and still needs human proofing • Requires software on computer or mobile + high-quality microphones 10 • Offline (not real-time) tools to extract some structured data from text reports
  • 11. How is VAL9000 different from Nuance Dragon Solutions VAL9000’s goal: Simplify practice of medicine • Action: Workflow optimization with • Two-way spoken conversations: two-way spoken interactions with find & save clinical information systems structured data • Replace keyboards & displays with • Self-proofing throughout speech recognition + artificial conversations intelligence + clinical workflows SYMPTOM CONSTIPATION CLINICAL SYSTEMS • Finds & saves structured clinical SYMPTOM NO DIARRHEA data: results, notes, orders, etc. ON MEDICATION MONOPRIL 10MG January 2011 • Automatically assembles text FAMILY HISTORY DIABETES MELLITUS documents from structured data INTAKE BP 112 70 INTAKE RR 18 • Manages alarms, alerts, follow-ups • Primary metric: Correctly understand and respond to user’s intent • Automatic 11 • No equipment or installable software report creation needed: Call & talk from any phone only when needed
  • 12. It’s working at Four piloted applications since 2006 • Bedside data capture • Verbal order entry • Care-coordination and patient rounds phone service • Assets & personnel tracking via hospital-wide WiFi network Eight system interfaces • Radiology, oncology, pathology, lab, pharmacy (HL7, SOAP) January 2011 • Bedside monitors (Unity Network) • Nursing documentation system (Essentris, Clinicomp) • Cisco Wireless Location Manager 12
  • 13. Benefits: Efficient, convenient, immediate turnaround Productive on-the-go data retrieval and entry • No paper charts or click-click-type-click-type-type-click-click… • No paper scribbling or remembering for later: Immediate entry of care plans, orders, Rx • Real-time compliance with workflow & care protocols Collaboration among providers (and patients) • Communication “through medical record” instead of interruptive phone calls, voicemail, “phone tag” January 2011 Less time learning new systems 13
  • 14. ROI: Hard-dollar savings Gives MD’s and RN’s more time to see patients Eliminates or reduces data-entry clerks and scribes Reduces need for multi-system portals, mobile apps SaaS: No CapX or added infrastructure Helps comply with meaningful-use requirements Keeps logs for productivity & efficiency assessment January 2011 14
  • 15. System architecture EMR HIS RULES ENGINE PHR • ASR • HL7 • NLP (CLP) • User profiles • Web services UCS • TTS • Workflows • Custom • Telephony • Templates etc. • Care protocols • Alerts CONVERSATION DATA INTERFACE January 2011 ENGINE ENGINE • Uses off-the-shelf speech-recognition and speech-synthesis components • Artificial-intelligence technology incorporated in all engines 15 • HIPAA compliance shared by all engines
  • 16. System interfaces Interoperates using standard interface protocols • HL7 • Web services • Custom Interoperates with multiple systems • Automatically routes data to/from data repositories (e.g., EMR, RIS, HIS, LIS) and real-time devices (e.g., bedside monitors) January 2011 16
  • 17. Voice user interface “Free form”, natural conversations • Users speak as they always do: No retraining required • Automatically handles accents, enunciation, pronunciation, etc. • Understands meaning, intent, jargon, acronyms, abbreviations, etc. • Verbal algebra, unit conversions, clinical calculators, date algebra Adaptable “verbosity” and hand-holding • Smart, silent, audio, verbose Multiple languages January 2011 • Could understand 4 (EN, ES, FR, DE); speaks 7 (+ CN, IT, JP) User identification and authentication • Voice-print, name & PIN, caller ID 17
  • 18. Frictionless implementation We take care of the rest • Rules & profiles • Data-exchange Customer selects interfaces When ready, customer initial application(s) • Telephony interfaces adds applications • Test and tweak • Go live • Analyze, tweak, optimize January 2011 18
  • 19. Price Hosted, in the cloud = No CapX or additional IT infrastructure Implementation fee + three SaaS options Per session Per port Per minute • Cents to • $100 to • 10¢ ‒ 20¢ dollars $1000 per minute per session per month January 2011 19
  • 20. MedVox: Consumer version of VAL 9000 Patients Emergency Caregivers room staff SECURE ACCESS OF PERSONAL HEALTH RECORDS January 2011 Emergency Doctors & response nurses medics 20
  • 21. Three to five years from now Smarter rules, More medical workflows, applications templates Deeper real-time More intelligent, integration with versatile clinical information conversations systems INTELLIGENT MEDICAL January 2011 ASSISTANTS 21
  • 22. About us • Computer science • Inventor: VAL 9000 (MS UC Berkeley, BS MIT) • Micro-electronics • Career launching and growing IT (MS Prague Polytechnic), startups computer science, neuroscience (PhDs UCLA) • Co-founder of highly successful healthcare IT & telemedicine • Research: clinical information venture systems, clinical trials, neural networks, artificial intelligence, natural language processing • Founder and CTO of highly successful provider of EMR portals on handheld devices January 2011 Richard Koffler Dr. Val Nenov CEO CTO 22
  • 23. Conversational interfaces for clinical information systems SM VAL9000, Inc. Simplifying the practice of medicine Richard Koffler January 2011 rk@val9000.com (310) 807-5786 Dr. Val Nenov val@val9000.com 23 January 2011