USAHA Annual Meeting Providence Rhode Island USA 27-30 October 2019 Presentations\2019\USAHA_Annual meeting of the US Animal Health Association

1. Annual meeting of the United States Animal
Health Association
Committee on Global Animal Health and
Trade
PRAGMATIST tool and other risk assessment
and analysis activities
Fabrizio Rosso – Deputy Executive Secretary EuFMD

2. ExCom and Member States
39 Member States
Executive Committee
One of the first Commissions of the Food
and Agriculture Organization
established in 1954
 Established to support member countries in the
European region to prevent and/or control FMD
 Funded by Member States and the European
Commission
An eight-member Executive Committee with one
Chairperson, two Vice-Chairs, and 1 observer –
selected by the Commission at the General Session –
governs the Commission between the Sessions. The
current membership of the Executive Committee
(2019-2021) is as follow:
• Martin Blake, Ireland (Vice President)
• JeanLuc Angot, France (Vice President)
• Lajos Bognar (Hungary)
• Zoran Atanasov (North Macedonia)
• Nihat Pakdil (Turkey)
• Valentin Almansa (Spain)
• Olev Kalda (Estonia)
• Henrik Roest (Netherlands)
• Chrysoula Dile (Greece)

3. 1) Improve readiness for FMD crisis
management by member states
2) Reduce risk to Members from the FMD
situation in the European Neighborhood
3) Greater implementation of the Global
Strategy for the control of FMD
At all times maintain availability of
expertise required for emergency response
Three Pillars

4. https://www.youtube.com/watch?v=7uT_5njwmS4
Face-to-face and On-line training
programme

5. Global headline events (2017-2019)
Pool 1
Pool 2
Pool 3
Pool 4
Pool 6
Pool 5
Pool 7
South Africa (Limpopo)
Serotype SAT 2
Initially within the protection zone
Jan 2019: spill-over into surv. zone
leading to suspended status
Colombia
Serotype O
2018: 8 new outbreaks
Links to Venezuela
Central Zambia
Comoros
O/EA-2
East Mediterranean
O/ME-SA/PanAsia-2QOM-15
O/EA-3
A/ASIA/G-VII
Serotype SAT 2
North Africa
A/AFRICA in 2017
O/EA-3 in 2018/19
Southeast
and East Asia
O/ME-SA/Ind-2001e
Pakistan
O/ME-SA/Ind-2001e
Ag O/PanAsia-2
Turkey
O/ME-SA/PanAsia-2QOM-15
A/ASIA/G-VII

6. Risk to EuFMD Members from the European neighbourhood
FMDV
Type
FMDV
Topotype
Region Country
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
FMDV
Type
FMDV
Topotype
Region Country
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
Middle East Egypt Egypt
Algeria ISRAEL
Tunisia Palestine
Egypt Algeria
ISRAEL Libya
Palestine Mauritania
Afghanistan Morocco
Armenia Egypt
IRAN IRAQ
Kazakhstan ISRAEL
Russia Jordan
Turkey Palestine
Afghanistan Algeria
IRAN Libya
IRAQ Morocco
Turkey Tunisia
Egypt Afghanistan
Oman Georgia
Palestine IRAN
North Africa Libya Kazakhstan
Mauritania Russia
Turkey
O SEA West Eurasia Russia
Middle East
North Africa
O ME-SA
Middle East
North Africa
West Eurasia
SAT2 SAT2VII
Middle East
O
O EA-3
Asia1 Asia1ASIA West Eurasia
A
A AFRICA North AFrica
A ASIA
Middle East
West EurasiaRegion Type O Type A Type SAT2 Type Asia1 period
Middle East 68% 44% 36% -
84 months
(2012-2018)
North Africa 22% 5% 2% -
110 months
(2011 – 2019)
WestEurasia
(TCC , Turkey, Russia)
80% 84% - 42%
108 months
(2011 – 2018)

7. North Africa (Algeria, Mauritania) and most
countries in West Africa have reported an epizootic
of FMD in the 2018, with closely related strains of
serotype O (EA-3 topotype). In 2018-2019 the
epizootic affected Tunisia and Morocco.
Sufficient attention should be given to initiatives
on livestock prices, movements and risk mapping
in these areas and to improve primary surveillance
and early detection systems
FMD in West and North Africa
WRL: FMD Genotyping Report
Epidemiological links
Lateral flow device
deployment

8. Improved early warning for FMD and Similar TADs
Component Objective: Develop and implement integrated disease surveillance programs
focused on specific risk hubs, in order to provide updated risk information, optimize the
veterinary service resources and improve the effectiveness of control measures
implemented.
1. Identification risk hot-spots for
FAST diseases and development
of risk maps
2. Implementation of regular risk
based surveillance (RBS) for
multiple diseases
3. Regular participation in multi-
country risk information sharing
systems for FAST diseases

9. ExCom97
Weights to risk factors
Network analysisData management
qualitative risk mapping methodology at the country-level
Livestock mobility
Environmental features
Human and animal
population densities
Outcomes of surveillance
and control activities
GIS integration

10. Algeria
• 2018 FMD outbreaks
• Units at different level of risk
• 70% outbreaks at H and VH risk areas
Negligible
Low
High
Very high
Tunisia
• FMD outbreaks (period 2014-2018)
• Units at different level of risk
• 64% outbreaks at H and VH risk areas
Nodes and links
Work in progress… Work in progress…
Morocco
Work in progress…
Collection and analysis of
relevant data related with
animal mobility and other
FMD risk factors

11. Regional cooperation between
Transcaucasia and neighbouring countries
(statement of intention) Improved system for immediate and monthly
reporting of FMD outbreaks
Monthly reporting
level of implementation of the vaccination programmes
Risk information sharing
Sharing results of immunogenicity studies
2017-2019
Studies on retrospective analysis of market price and
animal movements

12. Thrace: coordinated surveillance activities
High-risk area for the introduction of exotic
diseases into Europe
BulgariaGreece Turkey
Current objectives of surveillance:
•increase confidence of freedom
•increase the likelihood of early detection of incursion

13. FMD RVF BEF LSD SGP PPR
Fever Fever Fever Fever Fever Fever
Depression Depression Depression Depression Depression Depression
Vescicles Vescicles/ulcers Erosive lesions
Drooling Drooling Drooling Drooling Drooling
Nasal discharge Nasal discharge Nasal discharge Nasal discharge
Lameness Lameness
Death young Death young Death (possible) Death
Abortion Abortion Abortion Abortion Abortion
Milk drop Milk drop Milk drop
Bloody diarrhea Cutaneous nodules Papules Diarrhea
Integrated approach allows for more synergies through
connecting and integrating different aspects and activities to be
the most effective.
Similar signs and symptoms
Same actors/stakeholders
FAST surveillance

14. Timely information sharing
Different providers (national and
international)
Different users with different
interests and exposed to different
risks
Importance to provide risk
information in time, to different
providers and to interested users
Use of the information
E.g. Prioritisation of Antigen Management with
International Surveillance Tool (PRAGMATIST)

15. Currently an excel spreadsheet, soon a WebApplication with 3 main sections:
(i) Source Area Score, (ii) Lineage Score and (iii) Vaccine effficacy
PRAGMATIST : The tool
Source area score: end-user’s
prioritization
Which region(s) is likely to be source of
FMDV?
Lineage distribution score: based on GMR records and
expert opinions from Ref. Lab and incl. GIFPs’
**need for more timely data in FMD endemic regions**
Relative prevalence of FMD virus lineages in each of
the source area
Source area score and lineage distribution score
combined to issue a lineage score
The higher the score, the more probable that this strain could a threat to enter
the free country in question
𝑙𝑖𝑛𝑒𝑎𝑔𝑒 𝑠𝑐𝑜𝑟𝑒 =
𝑠𝑜𝑢𝑟𝑐𝑒 𝑎𝑟𝑒𝑎 1
𝑠𝑜𝑢𝑟𝑐𝑒 𝑎𝑟𝑒𝑎 𝑛
(𝑙𝑖𝑛𝑒𝑎𝑔𝑒 𝑑𝑖𝑠𝑡𝑟𝑖𝑏𝑢𝑡𝑖𝑜𝑛 𝑠𝑐𝑜𝑟𝑒 ∗ 𝑠𝑜𝑢𝑟𝑐𝑒 𝑎𝑟𝑒𝑎 𝑠𝑐𝑜𝑟𝑒)

16. Currently an excel spreadsheet, soon a WebApplication with 3 main sections:
(i) Source Area Score, (ii) Lineage Score and (iii) Vaccine effficacy
PRAGMATIST : The tool
Vaccine data: most updated data from
VNTesting at WRLFMD
**need for more data from vaccine
manufacturer and sample submission from
non FMD free countries **
Manager Tool Summary
Compiling information from the 3 sections in a
user-friendly interface
Which strains are the most important to
maintain in my vaccine bank?

18. Animal health security through
Better preparedness and reduced
risk from fmd and similar Tads
(‘’HOLD-FAST””)

20. Our links
You tube : https://www.youtube.com/channel/UCCD9aTo3VPnXVu69ML5fXkw
Twitter https://twitter.com/eufmd
Instagram: https://www.instagram.com/eufmd/?hl=it
Soundcloud (podcast) : https://soundcloud.com/eufmd
Flickr: https://www.flickr.com/photos/eufmd/albums
Elearning: https://eufmdlearning.works/
Linkedin https://www.linkedin.com/company/the-european-commission-for-the-
control-of-foot-and-mouth-disease-eufmd/?viewAsMember=true