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URINARY TRACT INFECTION
NAME: JOSHUA GEORGE
CLASS: 3RD PHARMD
DEMOGRAPHIC DETAILS
• NAME: xyz
• AGE: 64yrs
• SEX: female
• WARD: Nephrology
• REASON FOR ADMISSION: C/O fever with chills, burning micturition,
pain in abdomen{these complaints was there from 5-6days}, vomiting
{since 4 days}, decrease In appetite{since 5 days}
VITAL SIGNS
DATE 13/2/21 14/2/21 15/2/21 16/2/21
TEMP (°F) 99 98.5 98.5 98.5
BP (mmHg) 130/70 120/60 120/60 120/60
PULSE RATE (BPM) 90 90 90 90
RESP. RATE 22 22 22 22
LABORATORY INVESTGATION
TEST TEST VALUE NORMAL VALUE
CRP >320mg/dl <10mg/dl
FBS 100mg/dl <100mg/dl
SERUM CREATININE 1.30 mg/dl 0.8-1.2mg/dl
SPECIFIC GRAVITY 1.005 1.002-1.003
PUS CELLS 6-8/hpf 0-2hpf
SERUM SODIUM 133mmol/l 135-145mmol/l
SERUM CHLORINE 95mmol/l 96-106mmol/l
SERUM CALCIUM 8.9mg/dl 8-10mg/dl
MAGNESIUM 2.4mg/dl 1.7-2.2mg/dl
BUN 9mmol/l 2.5-7.1mmol/l
RBC 10-12/hpf 0-3/hpf
EPITHELIAL CELL 3-4/hpf 2-3/hpf
OTHER INVESTIGATION
• ULTRA SOUND ABDOMEN AND PELVIS: Moderate fatty infiltration of
liver
• URINE APPEARANCE: Slight turbid, proteinuria, glycosuria,
haematuria
DIAGNOSIS
• URINARY TRACT INFECTION{UTI}
TREATMENT GOAL
• Eradicate the infection
• prevent urosepsis
• reduce the likelihood of renal damage
PHARMACOLOGICAL TREATMENT
S.NO PRESCRIBED DRUGS DOSE, ROA DATES OF TREATMENT
T.NAME GENERIC NAME
INJ.PIPTAZ PIPERCILLIN+TAZOBA
CTOM
4.5g (IV)
TAB.SILODAL SILODOSIL 6mg/PO (0-0-1)
TAB.DOMSTAL DOMPERIDONE 10mg/PO(1-0-1)
TAB.BUSCOPAN HYOSINE BUTYL
BROMIDE
10mg/PO(1-0-1)
INJ.PARACETAMOL ACETAMINOPHEN 1g (IV) (1-0-1)
INJ.PANTOPRAZOL PANTOPRAZOL
✔ ✔ ✔
✔ ✔ ✔
✔ ✔ ✔
✔ ✔
✔ ✔ ✔ ✔
✔ ✔ ✔ ✔
13/2/21 14/2/21 15/2/21 16/2/21
1.
2.
3.
4.
5.
6. 40mg(IV) (1-0-0)
ADVERSE EFFECTS
• PIPTAZ: rash, pururitis, constipation,headache,diarrhea,
nausea,vomiting
• SILODAL: orthostatic hypotension, dizziness, headache,nasal
congestion
• DOMSTAL: dizziness, headache
• BUSCOPAN: constipation,dry mouth,blurred vision, increased HR
• PCM: constipation,liver failure,pruritis
• PANTOP: abdominal pain, diarrhea, headache, gastritis,
thrombocytopenia
PATIENT COUNSELLING
• We should ask them to wipe from front to back after urinating or a
bowel movement.
• Using hygienic garments
• They should drink plenty of fluids.
• Regular follow up with RFT.
• Educate the patient about the importance of Medication adherence
especially the antibiotic regimen.
PHARMACIST INTERVENTION
• Urine culture test has to be conducted ( to check for causative
organism is Gram +ve or Gram –ve)
• Treatment with Narrow spectrum antibiotics
• HBA1C to be ordered and addition of oral hypoglycaemic agent
Urinary Tract infection: Case study

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Urinary Tract infection: Case study

  • 1. URINARY TRACT INFECTION NAME: JOSHUA GEORGE CLASS: 3RD PHARMD
  • 2. DEMOGRAPHIC DETAILS • NAME: xyz • AGE: 64yrs • SEX: female • WARD: Nephrology • REASON FOR ADMISSION: C/O fever with chills, burning micturition, pain in abdomen{these complaints was there from 5-6days}, vomiting {since 4 days}, decrease In appetite{since 5 days}
  • 3. VITAL SIGNS DATE 13/2/21 14/2/21 15/2/21 16/2/21 TEMP (°F) 99 98.5 98.5 98.5 BP (mmHg) 130/70 120/60 120/60 120/60 PULSE RATE (BPM) 90 90 90 90 RESP. RATE 22 22 22 22
  • 4. LABORATORY INVESTGATION TEST TEST VALUE NORMAL VALUE CRP >320mg/dl <10mg/dl FBS 100mg/dl <100mg/dl SERUM CREATININE 1.30 mg/dl 0.8-1.2mg/dl SPECIFIC GRAVITY 1.005 1.002-1.003 PUS CELLS 6-8/hpf 0-2hpf SERUM SODIUM 133mmol/l 135-145mmol/l SERUM CHLORINE 95mmol/l 96-106mmol/l SERUM CALCIUM 8.9mg/dl 8-10mg/dl MAGNESIUM 2.4mg/dl 1.7-2.2mg/dl BUN 9mmol/l 2.5-7.1mmol/l RBC 10-12/hpf 0-3/hpf EPITHELIAL CELL 3-4/hpf 2-3/hpf
  • 5. OTHER INVESTIGATION • ULTRA SOUND ABDOMEN AND PELVIS: Moderate fatty infiltration of liver • URINE APPEARANCE: Slight turbid, proteinuria, glycosuria, haematuria
  • 7. TREATMENT GOAL • Eradicate the infection • prevent urosepsis • reduce the likelihood of renal damage
  • 8. PHARMACOLOGICAL TREATMENT S.NO PRESCRIBED DRUGS DOSE, ROA DATES OF TREATMENT T.NAME GENERIC NAME INJ.PIPTAZ PIPERCILLIN+TAZOBA CTOM 4.5g (IV) TAB.SILODAL SILODOSIL 6mg/PO (0-0-1) TAB.DOMSTAL DOMPERIDONE 10mg/PO(1-0-1) TAB.BUSCOPAN HYOSINE BUTYL BROMIDE 10mg/PO(1-0-1) INJ.PARACETAMOL ACETAMINOPHEN 1g (IV) (1-0-1) INJ.PANTOPRAZOL PANTOPRAZOL ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ 13/2/21 14/2/21 15/2/21 16/2/21 1. 2. 3. 4. 5. 6. 40mg(IV) (1-0-0)
  • 9. ADVERSE EFFECTS • PIPTAZ: rash, pururitis, constipation,headache,diarrhea, nausea,vomiting • SILODAL: orthostatic hypotension, dizziness, headache,nasal congestion • DOMSTAL: dizziness, headache • BUSCOPAN: constipation,dry mouth,blurred vision, increased HR • PCM: constipation,liver failure,pruritis • PANTOP: abdominal pain, diarrhea, headache, gastritis, thrombocytopenia
  • 10. PATIENT COUNSELLING • We should ask them to wipe from front to back after urinating or a bowel movement. • Using hygienic garments • They should drink plenty of fluids. • Regular follow up with RFT. • Educate the patient about the importance of Medication adherence especially the antibiotic regimen.
  • 11. PHARMACIST INTERVENTION • Urine culture test has to be conducted ( to check for causative organism is Gram +ve or Gram –ve) • Treatment with Narrow spectrum antibiotics • HBA1C to be ordered and addition of oral hypoglycaemic agent