In the dynamic realm of medical diagnostics, the convergence of technology and pathology has given rise to transformative methodologies, among which digital pathology stands out as a pioneering force. Traditional pathology, reliant on physical slides, is undergoing a paradigm shift with the integration of digital solutions. This article explores the intersection of digital pathology and Immunohistochemistry-Pathology Reporting System (IHC-PRS), shedding light on their synergistic potential in advancing diagnostic precision.